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TSARRIGAPDAKNRGVLLDTAEELMIEEGYAAVTSRRVASEAGLKPQLVHYYFRTMEELFLELFRRRAEE GLRAQAQALQSPKPLWALWRLGSDPAFARISMEFMALANHRKALRAEIAHYAERFRDEQRRVITAALQRY GVDSQDVPPVVWTVLMASLSRFLVLEKALGMSGGHAETIELVESYLRRLEGEP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4693 | - | - | 100% (194) | transcriptional regulator |
| M. marinum M | MMAR_0923 | - | 9e-08 | 33.33% (81) | transcriptional regulator |
| M. marinum M | MMAR_5193 | - | 7e-07 | 33.07% (127) | hypothetical protein MMAR_5193 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 2e-05 | 26.70% (191) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2518 | - | 2e-74 | 69.59% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 1e-05 | 26.70% (191) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-05 | 28.57% (70) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2952c | - | 7e-07 | 28.00% (125) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0966 | - | 2e-90 | 81.87% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4779 | - | 7e-80 | 72.68% (194) | regulatory protein |
| M. thermoresistible (build 8) | TH_3070 | - | 7e-80 | 71.65% (194) | PUTATIVE probable regulatory protein |
| M. ulcerans Agy99 | MUL_0675 | - | 2e-07 | 38.33% (60) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4140 | - | 3e-76 | 71.13% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0310|M.bovis_AF2122/97 -----------MGVP--------------AKKKQQQGERSRESILDATER
Rv0302|M.tuberculosis_H37Rv -----------MGVP--------------AKKKQQQGERSRESILDATER
MMAR_4693|M.marinum_M -----------MTSA---------------RRIGAPDAKNRGVLLDTAEE
MAV_0966|M.avium_104 -----------MTSASSGASSGASS---GARRIGAPDAKNRGLLLDAAER
MSMEG_4779|M.smegmatis_MC2_155 -----------MASA---------------RRIGAPDAKNRIVLLDAAEA
TH_3070|M.thermoresistible__bu -----------MASG---------------RRIGTPDAKNRGVLLDAAER
Mflv_2518|M.gilvum_PYR-GCK -----------MAAP---------------RRIGAPDAKNRVVLLDAAEQ
Mvan_4140|M.vanbaalenii_PYR-1 -----------MTSP---------------RRIGAPDAKNRVVLLDAAEQ
MAB_2952c|M.abscessus_ATCC_199 --MYARKNAKVIALGGWSVVVANLEGRASRRTQAQRSAEMRTRLLDATVE
MUL_0675|M.ulcerans_Agy99 -----------------------------MPTAAERGAQTRAALMAAAVA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
. * :: .:
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Rv0302|M.tuberculosis_H37Rv LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
MMAR_4693|M.marinum_M LMIEEGYAAVTSRRVASEAGLKPQLVHYYFRTMEELFLELFRRRAEEGLR
MAV_0966|M.avium_104 LMLEEGYAAVTSRRLASRAGLKPQLVHYYFRTMEELFLEVFRRRAEEGLA
MSMEG_4779|M.smegmatis_MC2_155 LMIDEGYAAVTSRRVAERAGLKPQLVHYYFRTMDDLFLAVFRRRAEEGLA
TH_3070|M.thermoresistible__bu LMLEEGYVAVTSRRVAEKAGLKPQLVHYYFRTMDDLFLEVFRRRAEEGLR
Mflv_2518|M.gilvum_PYR-GCK LLIEEGYAAVTSRRVADRAGLKPQLVHYYFRTMEDLFLAVFHRRAEEGLA
Mvan_4140|M.vanbaalenii_PYR-1 LLIEEGYAAVTSRRVADRAGLKPQLVHYYFRTMEDLFLAVFHRRAEEGLA
MAB_2952c|M.abscessus_ATCC_199 CLVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQRTQ
MUL_0675|M.ulcerans_Agy99 VIAERGWGAATTRMVAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: .*: .. : . .*: :* : : : ..
Mb0310|M.bovis_AF2122/97 AIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPVV
Rv0302|M.tuberculosis_H37Rv AIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAV
MMAR_4693|M.marinum_M AQAQALQSPKPL--WALWRLGSDPAFARISMEFMALANHRKALRAEIAHY
MAV_0966|M.avium_104 VQAQALQSDQPL--WAVWRFGTDPAFTQISMEFMALANHRKDMRAEIAYY
MSMEG_4779|M.smegmatis_MC2_155 AQARALDSPQPL--WALWRFGIDPSATRLTMEIMGVANHRKALRTEIGRY
TH_3070|M.thermoresistible__bu AQEEAFASPQPL--WALWRFGTDPAGTRLTMELMGLANHRPALRAEMARY
Mflv_2518|M.gilvum_PYR-GCK VLSTALRSAQPL--WALWRFSTAPEATRLTMEFMGLANHRKALRAEIVYY
Mvan_4140|M.vanbaalenii_PYR-1 VLSTALASPQPL--WALWRFSTAPEATRLTMEFMGLANHRKALRAEIVYY
MAB_2952c|M.abscessus_ATCC_199 AAIREIARLQGN-PDPVSAVLDFMWEIHQGPIFVATMELWIASRTD-KVL
MUL_0675|M.ulcerans_Agy99 QVLDGLAGDSSS--QGIDRLIDAVSSYDVDDRNQNPAILVFGEMLLAATR
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNN--RQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRV
Mb0310|M.bovis_AF2122/97 AAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGV
Rv0302|M.tuberculosis_H37Rv AAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGV
MMAR_4693|M.marinum_M AERFRDEQRRVITAALQRYG-VDSQDVPPVVWTVLMASLSRFLVLEKALG
MAV_0966|M.avium_104 AERFRDEQQRAVAAALERYG-VQNKDVPPVVWTVLMTSLSRFLVLEQAIG
MSMEG_4779|M.smegmatis_MC2_155 AERFRDEQTKAMTAALDRYG-VNAADVPPIVWTFLATSVSRVMVMEQALG
TH_3070|M.thermoresistible__bu AERFREKERDAIAAILERYG-IDASDVPPVVWAVFAAAVSRMLVMEKAIG
Mflv_2518|M.gilvum_PYR-GCK AERFRQEQNRAISDALQRYG-MVSDDVPPVVWTVFATSVSQALVMERALG
Mvan_4140|M.vanbaalenii_PYR-1 AERFRQEQNRAIADALQRYG-TDFTDVPPVVWTVFATSVSQALVMERALG
MAB_2952c|M.abscessus_ATCC_199 AQQIQRMEPFVNSALAAAIVQLLPEHPAPAELAKIVYTAMDTLRGILIAS
MUL_0675|M.ulcerans_Agy99 YERLRMGLAEILGDYRSTLRQWLADQGGAIDPEATAALMFAAIDGLVLHR
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALIS--ADSRLDPHRARMVAVGLVGISVDCARYW
.: .
Mb0310|M.bovis_AF2122/97 YFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET---------------
Rv0302|M.tuberculosis_H37Rv YFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET---------------
MMAR_4693|M.marinum_M MSGGHAETIELVESYLRRLEGEP---------------------------
MAV_0966|M.avium_104 MSSGHAETVQLVESYLRRLEGEPKPIAGAPSSWTVHQGRIEQSTPLGPSL
MSMEG_4779|M.smegmatis_MC2_155 MSAGHAEVLEFCEGWLRRIEGEPLPIEAAG--------------------
TH_3070|M.thermoresistible__bu MSVGHKEILEFCEDWLRRLEGEPLPASDPDSVASA---------------
Mflv_2518|M.gilvum_PYR-GCK MDTGHAETFAFCEQWIRRFEGEPSPELADGHEMAPAQP------------
Mvan_4140|M.vanbaalenii_PYR-1 MDTGHAETFAFCEEWIRRLEGDPLPPLDQRA-------------------
MAB_2952c|M.abscessus_ATCC_199 FVDGDVERARRRWARASAHLRAVAVAAFPSLG------------------
MUL_0675|M.ulcerans_Agy99 VIDPRLRTLAIRPT-LRRLAGLPTAQTDERTPS-----------------
MLBr_00815|M.leprae_Br4923 LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL------------------
Mb0310|M.bovis_AF2122/97 ------------
Rv0302|M.tuberculosis_H37Rv ------------
MMAR_4693|M.marinum_M ------------
MAV_0966|M.avium_104 DTTTAPSTVRSQ
MSMEG_4779|M.smegmatis_MC2_155 ------------
TH_3070|M.thermoresistible__bu ------------
Mflv_2518|M.gilvum_PYR-GCK ------------
Mvan_4140|M.vanbaalenii_PYR-1 ------------
MAB_2952c|M.abscessus_ATCC_199 ------------
MUL_0675|M.ulcerans_Agy99 ------------
MLBr_00815|M.leprae_Br4923 ------------