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IEATARLMREEGYAAATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGAESALTRMRALLTEDDPLQA LWLMNSDTALTALNAEFMALANHRKAIGAELKAYAERVRDIETAAATMVLRANGIDLEEYPPVAISMLIA QAARSLCNEKAVGVTQGHDELRAFVQRQLSRLTAPAVASTTSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0847 | - | - | 100% (184) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0367 | - | 4e-42 | 50.57% (176) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0966 | - | 2e-38 | 46.24% (173) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 4e-05 | 37.50% (56) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1588 | - | 8e-75 | 78.86% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 4e-05 | 37.50% (56) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4089c | - | 2e-07 | 41.67% (48) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4693 | - | 1e-39 | 47.98% (173) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6032 | - | 5e-66 | 68.97% (174) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2984 | - | 8e-78 | 79.44% (180) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4875 | - | 3e-07 | 40.00% (60) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5169 | - | 7e-76 | 80.68% (176) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1561|M.bovis_AF2122/97 MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
Rv1534|M.tuberculosis_H37Rv MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
MAV_0847|M.avium_104 -----------------------MIEATARLMREEGYAAATSRRVAAEAG
TH_2984|M.thermoresistible__bu MPTTRQNRRSSDSGSVDTGARSRLIEATAQIMREEGYAAATSRRVAARAG
Mflv_1588|M.gilvum_PYR-GCK MPAAAKSR------PAD--ARGRLIEATAKVMRDEGYAAATSRRVAAEAG
Mvan_5169|M.vanbaalenii_PYR-1 MAASPKGR------GSDPNARQRLIEATARVMRDEGYAAATSRRVAAEAG
MSMEG_6032|M.smegmatis_MC2_155 MARVVKAG-PRTAKDKDAGTRQRLIEATAQVIRDEGYAAATTRRIAAQAG
MMAR_4693|M.marinum_M MTSARRIG------APDAKNRGVLLDTAEELMIEEGYAAVTSRRVASEAG
MAB_4089c|M.abscessus_ATCC_199 MSGRPRRISP---IREGNSTRDEILDASAELFTTDGFAATTTRRIAESVG
MUL_4875|M.ulcerans_Agy99 MTRTQLGRPVG---ASGEETRQRIIVATMQCVSKVGYARATIREIARTAN
:: :: . *: .* :* ..
Mb1561|M.bovis_AF2122/97 LAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEAPLRAL
Rv1534|M.tuberculosis_H37Rv LAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEAPLRAL
MAV_0847|M.avium_104 VKQALVYYYFPTMDDLFVEVLRAGAESALTRMRALLT-----EDDPLQAL
TH_2984|M.thermoresistible__bu VKQALVYYYFPTMDDLFVEVLRTGAEAALERMRTALT-----DDDPLRAL
Mflv_1588|M.gilvum_PYR-GCK VKQALVYYYFPTMDDLFVEVLRVGGESSLEHMRAALT-----NDDPLRAL
Mvan_5169|M.vanbaalenii_PYR-1 VKQALVYYYFPTMDDLFVEVLRAGGESALEHMRAALT-----NDDPLHAL
MSMEG_6032|M.smegmatis_MC2_155 VRSALVYYYFDTLDDLYIAVLRNGADVALERMREAVA-----ADDPLRAL
MMAR_4693|M.marinum_M LKPQLVHYYFRTMEELFLELFRRRAEEGLRAQAQALQ-----SPKPLWAL
MAB_4089c|M.abscessus_ATCC_199 IQQASLYYHFKTKDDILDALLAMTIDQPLHYAALIADR----PEAPVVRL
MUL_4875|M.ulcerans_Agy99 VTSASLYNYFPNKSELIKETIAARADAAMPRLRRAAEG----GGNIVDRI
: :: :* . .:: : : : :
Mb1561|M.bovis_AF2122/97 LQAAV-QATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDIE
Rv1534|M.tuberculosis_H37Rv LQAAV-QATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDIE
MAV_0847|M.avium_104 WLMNS-DTALTALNAEFMALANHRKAIGAELKAYAERVR--------DIE
TH_2984|M.thermoresistible__bu WELNS-DTRLTSLNSEFIALANHRKAIRAELKAYAERVR--------DIE
Mflv_1588|M.gilvum_PYR-GCK WLINS-EAGRTGLNAEFMALANHRKAIRVELKAYAERVR--------DIE
Mvan_5169|M.vanbaalenii_PYR-1 WLINN-DASRTGLNTEFMALANHRKAIRVELRAYAERVR--------DIE
MSMEG_6032|M.smegmatis_MC2_155 WLLNS-DARLSVLNTEFMALANHRKTIGAELKAYSERVR--------DIE
MMAR_4693|M.marinum_M WRLGS-DPAFARISMEFMALANHRKALRAEIAHYAERFR--------DEQ
MAB_4089c|M.abscessus_ATCC_199 YALALGDAAQLAASRWNLGALYLLPDLRAERFSAFRRKRDQLRTHYQELA
MUL_4875|M.ulcerans_Agy99 EAVLDECGELIREYPQLAAFEFAIRAEDGIAVDAQEGSGQLG-----EVG
. :
Mb1561|M.bovis_AF2122/97 AVVVAAQRRGEVVEAPSRMAAYTLAALVG---QLAHRRLNTD--DNVTAA
Rv1534|M.tuberculosis_H37Rv AVVVAAQRRGEVVEAPSRMAAYTLAALVG---QLAHRRLNTD--DNVTAA
MAV_0847|M.avium_104 TAAATMVLRANGIDL-EEYPPVAISMLIA---QAAR-SLCNE--KAVGVT
TH_2984|M.thermoresistible__bu TAAVTVALRARGVDL-DDHPPVAVSMLIA---QIAR-SLCNE--RAVGVT
Mflv_1588|M.gilvum_PYR-GCK TAAVTVALRANGVDL-QEHPPVVVSMLIA---QIAR-SLCNE--DAVGVT
Mvan_5169|M.vanbaalenii_PYR-1 TAAVTVALRANGVDL-DEHPPVVISMLIA---QVAR-SLCNE--VAVGVT
MSMEG_6032|M.smegmatis_MC2_155 TTAVAMVMRTHGIDT-EQYPPVVMSMLLT---QSAR-SLSNE--EAVGVT
MMAR_4693|M.marinum_M RRVITAALQRYGVDS-QDVPPVVWTVLMA---SLSR-FLVLE--KALGMS
MAB_4089c|M.abscessus_ATCC_199 AAACRASMLRAGVERLPFRLVESVIMLRADGDSIAPEALADATLRVVGVT
MUL_4875|M.ulcerans_Agy99 FTAFREIIRGLVEDARRRGELAEQADTAG---AIEAIYALIYGLTELAAT
. : : :
Mb1561|M.bovis_AF2122/97 QVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv QVADFVVSLVLDGLRPRALAVGARGGRAART
MAV_0847|M.avium_104 QGHDELRAFVQRQLSRLTAPAVASTTSA---
TH_2984|M.thermoresistible__bu LGHDELRAFMDRLMTQLGAPARASAPPPAQR
Mflv_1588|M.gilvum_PYR-GCK LGHEEMRAWVDRQLALLAAEPGG--------
Mvan_5169|M.vanbaalenii_PYR-1 LGHDEMRAYVERQLKLLAPVTGG--------
MSMEG_6032|M.smegmatis_MC2_155 QGHAEFRAFVDQILQRFTPTEPAT-------
MMAR_4693|M.marinum_M GGHAETIELVESYLRRLEGEP----------
MAB_4089c|M.abscessus_ATCC_199 GDAGEIEGAARVLLGQLGWPVAIPKR-----
MUL_4875|M.ulcerans_Agy99 LPLDQFHAALSAAKGLIRGTLFRC-------