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TDAPRRTYGGQSADARRLARRARLLDAAIEVIADNAWRTLTVDRLCADAGLNKRYFYESFATLDDVATAV VDDISEDVRTATMDVAAQRADEPLDQQARAVVDALVRTLVEDPRRGRILLGGVAGSVALHEHRGAVMRGL TAVLVSHARSVHGVELEKDPLAEVAPAFIVGGTADAILAYLDGRARMSLDSLVTALTTLWLITGNGAAEV ARHRLDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1526 | - | - | 100% (218) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4631 | - | 8e-22 | 30.90% (178) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4611 | - | 1e-19 | 30.51% (177) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 5e-16 | 32.49% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 3e-15 | 31.98% (197) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1638 | - | 2e-27 | 39.38% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 2e-20 | 30.68% (176) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 9e-18 | 31.79% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1168 | - | 8e-77 | 65.71% (210) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 3e-21 | 33.16% (196) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 7e-19 | 32.34% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 1e-18 | 32.97% (182) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3142|M.marinum_M ---MFDVRSRNTRWGGRTGAERRAERRQQLIEAATEIWSESG--WAAVTM
MAV_3986|M.avium_104 -------MSSPSRWAGVPLKDRRAERRALLVEAAYRLFGSEG--EAAVSV
Mflv_1526|M.gilvum_PYR-GCK -----MTDAPRRTYGGQSADARRLARRARLLDAAIEVIADNA--WRTLTV
MSMEG_1168|M.smegmatis_MC2_155 --------MSQRSYAGQSAEERRRLRRARLLDAAMDAMCANA--WRAVTV
Mb0281c|M.bovis_AF2122/97 ------MTRSDRPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
Rv0275c|M.tuberculosis_H37Rv ------MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
MUL_1200|M.ulcerans_Agy99 ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
TH_0801|M.thermoresistible__bu MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
MAB_1638|M.abscessus_ATCC_1997 ----MVTKQATGLYGGRTADERRAERRRRLLEAGLEVMASSG--WAATTV
Mvan_0313|M.vanbaalenii_PYR-1 ----------------MSAEERHRNRRTRLIEAATELIGTRG--VAAATV
* ** :.:. ::
MMAR_3142|M.marinum_M RGVCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDMLGEVSALFDERVDR
MAV_3986|M.avium_104 RSVCRECGLNTRYFYESFRDTDDLLGAVYDRVS-EQLEEVIAAAIEQAGD
Mflv_1526|M.gilvum_PYR-GCK DRLCADAGLNKRYFYESFATLDDVATAVVDDISEDVRTATMDVAAQRADE
MSMEG_1168|M.smegmatis_MC2_155 DKLCASAGLNKRYFYENFTHLDSVAAAVIDDIAADVRTAALTALAGAASR
Mb0281c|M.bovis_AF2122/97 RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVP--
Rv0275c|M.tuberculosis_H37Rv RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVP--
MUL_1200|M.ulcerans_Agy99 RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVP--
TH_0801|M.thermoresistible__bu RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAAAP--
MAB_1638|M.abscessus_ATCC_1997 REICKTAGLNTRYFYECFDGLDELLVAVFDWIIEDSIATAGSAMAAADKD
Mvan_0313|M.vanbaalenii_PYR-1 TAVCAESGVTSRYFYQHFSGRDALLRAVYQQLYATFQEVIVDAIPDAGEP
:* *:. ****: * : . . : :
MMAR_3142|M.marinum_M PPIETITAAIAIVVDRIARDPGRAHILLAQHVGSSPLQDRRAVALQ-EAT
MAV_3986|M.avium_104 SLRARTRAGIAAVLGFSSADPRRGRVLFTDAR-TNPVLAARRRATQ-DML
Mflv_1526|M.gilvum_PYR-GCK PLDQQARAVVDALVRTLVEDPRRGRILLGGVAGSVALHEHRGAVMRGLTA
MSMEG_1168|M.smegmatis_MC2_155 PLDEQAAVAMDALVHILLDDPRRARVLLGGVASSPSLQQHREAVMRGLTK
Mb0281c|M.bovis_AF2122/97 -AREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESS--ALF
Rv0275c|M.tuberculosis_H37Rv -AREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESS--ALF
MUL_1200|M.ulcerans_Agy99 -PPEQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESS--ALF
TH_0801|M.thermoresistible__bu -RRDQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESG--ALF
MAB_1638|M.abscessus_ATCC_1997 -SRSQVHAGVVGAVTALTADPRRARVIATEAMGSQRLTRRRMRLT--HYM
Mvan_0313|M.vanbaalenii_PYR-1 -PEVLAYAPIRRLVSMIDNDPRLGRILFVESATEPLLRELRSELMAGFTD
. : : *. .::: : *
MMAR_3142|M.marinum_M QLVVEASRPHLREDADETALRMDTLVAVGGFVEVITAWHSGLLAVTEKEV
MAV_3986|M.avium_104 RQGVLSEGWRLNPRSDPVAAEVAAAMYTGAMAELAQQWLAGHLGGDLDAV
Mflv_1526|M.gilvum_PYR-GCK VLVSHARSVHGVELEKDPLAEVAPAFIVGGTADAILAYLDGRARMSLDSL
MSMEG_1168|M.smegmatis_MC2_155 VLVTHARTVHGVELETDPLSQVAPAFLVGGTADAILAFVDGRAKLSREQL
Mb0281c|M.bovis_AF2122/97 AMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQL
Rv0275c|M.tuberculosis_H37Rv AMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQL
MUL_1200|M.ulcerans_Agy99 AMLSGQHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQL
TH_0801|M.thermoresistible__bu AMLSGQHVGSTMQLPENERIKATSHFVVGGVGQTIGAWLAGEVRLSPEAL
MAB_1638|M.abscessus_ATCC_1997 ALMLGAARAEFDPEADPNYTAVQAEALAAGVAGTVLAWLDGRLRLEREEL
Mvan_0313|M.vanbaalenii_PYR-1 LVLREARLHLDIADSAVGVAHLASTLGVGGLFEVLRRRLDGELEFTTDEL
. ... * :
MMAR_3142|M.marinum_M VAHTSRLAETLAQRYVVSG-------------------------------
MAV_3986|M.avium_104 VDYASKLVLR----------------------------------------
Mflv_1526|M.gilvum_PYR-GCK VTALTTLWLITGNGAAEVARHRLDG-------------------------
MSMEG_1168|M.smegmatis_MC2_155 VDSLATLWLITGNGATQTARARHEAL------------------------
Mb0281c|M.bovis_AF2122/97 VDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPAR
Rv0275c|M.tuberculosis_H37Rv VDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPAR
MUL_1200|M.ulcerans_Agy99 VDQLASLLDELSDPRLYGLR----GTRAGATAASPAQ-------------
TH_0801|M.thermoresistible__bu IDQLASVIDQLAKPELFRAD------------------------------
MAB_1638|M.abscessus_ATCC_1997 AEYTAQFVDQAMFTPLPVHNSVEH--------------------------
Mvan_0313|M.vanbaalenii_PYR-1 VQHCAGFLGSLGNYVLLQNTDQSATTEARPHR------------------
: .
MMAR_3142|M.marinum_M --
MAV_3986|M.avium_104 --
Mflv_1526|M.gilvum_PYR-GCK --
MSMEG_1168|M.smegmatis_MC2_155 --
Mb0281c|M.bovis_AF2122/97 RS
Rv0275c|M.tuberculosis_H37Rv RS
MUL_1200|M.ulcerans_Agy99 --
TH_0801|M.thermoresistible__bu --
MAB_1638|M.abscessus_ATCC_1997 --
Mvan_0313|M.vanbaalenii_PYR-1 --