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VSQRSYAGQSAEERRRLRRARLLDAAMDAMCANAWRAVTVDKLCASAGLNKRYFYENFTHLDSVAAAVID DIAADVRTAALTALAGAASRPLDEQAAVAMDALVHILLDDPRRARVLLGGVASSPSLQQHREAVMRGLTK VLVTHARTVHGVELETDPLSQVAPAFLVGGTADAILAFVDGRAKLSREQLVDSLATLWLITGNGATQTAR ARHEAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1168 | - | - | 100% (216) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0612 | - | 6e-19 | 32.47% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1355 | - | 2e-16 | 28.95% (190) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 8e-17 | 31.66% (199) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1526 | - | 7e-77 | 65.71% (210) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0825c | - | 3e-16 | 28.93% (197) | hypothetical protein Rv0825c |
| M. leprae Br4923 | MLBr_01070 | - | 7e-05 | 23.39% (171) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1638 | - | 1e-25 | 37.37% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3144 | - | 3e-20 | 30.21% (192) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 2e-20 | 33.16% (196) | FadD27 protein |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 6e-20 | 31.12% (196) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 2e-18 | 30.61% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 9e-20 | 29.90% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1168|M.smegmatis_MC2_155 -----------MSQRSYAGQSAEERRRLRRARLLDAAMDAMCANA--WRA
Mflv_1526|M.gilvum_PYR-GCK --------MTDAPRRTYGGQSADARRLARRARLLDAAIEVIADNA--WRT
MMAR_3144|M.marinum_M ----------MSPARVYGGLSATQRDAQRRALLIDAAVALMGKQG--AAA
Mvan_0313|M.vanbaalenii_PYR-1 -------------------MSAEERHRNRRTRLIEAATELIGTRG--VAA
Mb0281c|M.bovis_AF2122/97 -------MTRSD--RPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAE
MAV_4882|M.avium_104 ----MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLDLLGAEQQNIAA
MUL_1200|M.ulcerans_Agy99 -------------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAE
TH_0801|M.thermoresistible__bu ---MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAE
MAB_1638|M.abscessus_ATCC_1997 -------MVTKQATGLYGGRTADERRAERRRRLLEAGLEVMASSG--WAA
Rv0825c|M.tuberculosis_H37Rv -------MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAG--GPA
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERP--LGD
*. :: . :
MSMEG_1168|M.smegmatis_MC2_155 VTVDKLCASAGLNKRYFYENFTHLDSVAAAVIDDIAADVRTAALTALAGA
Mflv_1526|M.gilvum_PYR-GCK LTVDRLCADAGLNKRYFYESFATLDDVATAVVDDISEDVRTATMDVAAQR
MMAR_3144|M.marinum_M CTVTAVCTESGVTSRYFYQQFRDRDALLRAMFTKISTTFQAVITKAIPDD
Mvan_0313|M.vanbaalenii_PYR-1 ATVTAVCAESGVTSRYFYQHFSGRDALLRAVYQQLYATFQEVIVDAIPDA
Mb0281c|M.bovis_AF2122/97 LTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAV
MAV_4882|M.avium_104 VTVRGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAELAATTQAAVTAV
MUL_1200|M.ulcerans_Agy99 LTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATV
TH_0801|M.thermoresistible__bu LTVRAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAAA
MAB_1638|M.abscessus_ATCC_1997 TTVREICKTAGLNTRYFYECFDGLDELLVAVFDWIIEDSIATAGSAMAAA
Rv0825c|M.tuberculosis_H37Rv LTVRAVCRHAGLTERYFYESFADREHFVRAVYDDVCTRAMATLTS-----
MLBr_01070|M.leprae_Br4923 FSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQL
:: :. :*: ** * : . : : .
MSMEG_1168|M.smegmatis_MC2_155 ASRPLDEQAAVAMDALVHILLDDPRRARVLLGGVASSPSLQQHREAVMRG
Mflv_1526|M.gilvum_PYR-GCK ADEPLDQQARAVVDALVRTLVEDPRRGRILLGGVAGSVALHEHRGAVMRG
MMAR_3144|M.marinum_M TVA-PQELAYAPIKALVQMIENDPSMARILFVESGAEPLLRQLRSELMSE
Mvan_0313|M.vanbaalenii_PYR-1 GEP-PEVLAYAPIRRLVSMIDNDPRLGRILFVESATEPLLRELRSELMAG
Mb0281c|M.bovis_AF2122/97 P---AREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSAL
MAV_4882|M.avium_104 P---AHEQTRAGMANIVRTITEDARVGRLLFSTQLADPVVVRKRAESSAL
MUL_1200|M.ulcerans_Agy99 P---PPEQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSAL
TH_0801|M.thermoresistible__bu P---RRDQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESGAL
MAB_1638|M.abscessus_ATCC_1997 DKD-SRSQVHAGVVGAVTALTADPRRARVIATEAMGSQRLTRRRMRLTHY
Rv0825c|M.tuberculosis_H37Rv -----AQTPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPN
MLBr_01070|M.leprae_Br4923 PAD-PAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQ
: . . . : .
MSMEG_1168|M.smegmatis_MC2_155 LTKV--LVTHARTVHGVELETDPLSQVAPAFLVGGTADAILAFVDGRAKL
Mflv_1526|M.gilvum_PYR-GCK LTAV--LVSHARSVHGVELEKDPLAEVAPAFIVGGTADAILAYLDGRARM
MMAR_3144|M.marinum_M FAEL--VLREARLHLDIPSEVIQVADLAATYGVGGLFEILRRWIDGQLNL
Mvan_0313|M.vanbaalenii_PYR-1 FTDL--VLREARLHLDIADSAVGVAHLASTLGVGGLFEVLRRRLDGELEF
Mb0281c|M.bovis_AF2122/97 FAML--SGQHAVDTLHAPANDH--VKAVAHFAVGGVGQTISAWLAGDVRL
MAV_4882|M.avium_104 FAML--SGQHVGDALRMPANDR--IKAAAHFVVGGVAQTISAWLAGEVRL
MUL_1200|M.ulcerans_Agy99 FAML--SGQHAGDALRIPANDR--IKVGAHFIVGGVAQTISAWIEGDVEL
TH_0801|M.thermoresistible__bu FAML--SGQHVGSTMQLPENER--IKATSHFVVGGVGQTIGAWLAGEVRL
MAB_1638|M.abscessus_ATCC_1997 MALM--LGAARAEFDPEADPNY--TAVQAEALAAGVAGTVLAWLDGRLRL
Rv0825c|M.tuberculosis_H37Rv FIEL--LQRKLSRIVDP-----VLQKLVATSLIGALTGLFTAYLNGRLGA
MLBr_01070|M.leprae_Br4923 WIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLI
MSMEG_1168|M.smegmatis_MC2_155 SREQLVDSLATLWLITGNGATQTARARHEAL-------------------
Mflv_1526|M.gilvum_PYR-GCK SLDSLVTALTTLWLITGNGAAEVARHRLDG--------------------
MMAR_3144|M.marinum_M STEVLIEHCAGFLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR------
Mvan_0313|M.vanbaalenii_PYR-1 TTDELVQHCAGFLGSLGNYVLLQNTDQSAT-------TEARPHR------
Mb0281c|M.bovis_AF2122/97 DPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSS
MAV_4882|M.avium_104 EPDQLVDQLAALLDELAEPALYRR--TETPAQS-----------------
MUL_1200|M.ulcerans_Agy99 EPGQLVDQLASLLDELSDPRLYGLRGTRAGATAASPAQ------------
TH_0801|M.thermoresistible__bu SPEALIDQLASVIDQLAKPELFRAD-------------------------
MAB_1638|M.abscessus_ATCC_1997 EREELAEYTAQFVDQAMFTPLPVHNSVEH---------------------
Rv0825c|M.tuberculosis_H37Rv TRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN-----------
MLBr_01070|M.leprae_Br4923 PDKKVIDTLVHIWLASIYGS------------------------------
. . .
MSMEG_1168|M.smegmatis_MC2_155 -------
Mflv_1526|M.gilvum_PYR-GCK -------
MMAR_3144|M.marinum_M -------
Mvan_0313|M.vanbaalenii_PYR-1 -------
Mb0281c|M.bovis_AF2122/97 ARPARRS
MAV_4882|M.avium_104 -------
MUL_1200|M.ulcerans_Agy99 -------
TH_0801|M.thermoresistible__bu -------
MAB_1638|M.abscessus_ATCC_1997 -------
Rv0825c|M.tuberculosis_H37Rv -------
MLBr_01070|M.leprae_Br4923 -------