For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPESESQPHGLRERKKVQTRLAIRRAAFELFDTQGYANTTVDQIAEAADVSPRTLYRYFGVKEALLISDD QISPIVEAFADAPPDLPIVDAYRHAVATVFADLTPEEREDAAAGQRMMYGIPEARGLIYSEYIRLIEMIA EAMVSRPDAPAAAEERRVIAGAIVGVLIATSHETPMPDTELENSLTILSKRMAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5173 | - | - | 100% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3877 | - | 7e-62 | 58.55% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0350 | - | 9e-43 | 46.49% (185) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 1e-07 | 26.95% (167) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0691c | - | 1e-07 | 26.95% (167) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 3e-05 | 25.30% (166) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 2e-09 | 27.93% (179) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_2812 | - | 4e-11 | 36.73% (98) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 2e-39 | 44.79% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 9e-16 | 44.90% (98) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4253 | - | 2e-11 | 48.53% (68) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2933 | - | 4e-11 | 36.73% (98) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1156 | - | 1e-70 | 70.43% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5173|M.gilvum_PYR-GCK MPESESQPHGLRERKKVQTRLAIRRAAFELFDTQGYANTTVDQIAEAADV
Mvan_1156|M.vanbaalenii_PYR-1 MSGHD-RPQSLRERKKVRTRLAIRREAFRLFAKQGYANTTVEQIAEAADV
MAV_4894|M.avium_104 MPASE-APPGLRERKKIKTRQAIRREAFRLIEQNGYAATTVEQIAEAADV
Mb0710c|M.bovis_AF2122/97 -----MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGI
Rv0691c|M.tuberculosis_H37Rv -----MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGI
MAB_3837|M.abscessus_ATCC_1997 ----MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGI
MMAR_2812|M.marinum_M ----MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREAGV
MUL_2933|M.ulcerans_Agy99 ----MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREAGV
MSMEG_5673|M.smegmatis_MC2_155 -MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVEQIAAAAEV
TH_4253|M.thermoresistible__bu ---------------------MLTDAAVELFLRHGYENTTVDQIAAVADV
MLBr_02568|M.leprae_Br4923 ------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQI
: *. :*: .:: :* * :
Mflv_5173|M.gilvum_PYR-GCK SPRTLYRYFGVKEALLISD--DQISPIVEAFADAPPDLPIVDAYRHAVAT
Mvan_1156|M.vanbaalenii_PYR-1 SPRTFYRYFGVKERLLISD--DKISPIVEAFIAAPKELPIVPAYRHAVGT
MAV_4894|M.avium_104 SPSTFFRYFGSKESLLLAD--DLDPLILDALKAQPRELSLPQAFRRAYAT
Mb0710c|M.bovis_AF2122/97 ARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLA
Rv0691c|M.tuberculosis_H37Rv ARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLA
MAB_3837|M.abscessus_ATCC_1997 ARRTVFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTALRQAVLT
MMAR_2812|M.marinum_M TERTFFRHFPTKEAVLFQDYENQLEWLAQALAQRPVSEPLFDAVLASVAA
MUL_2933|M.ulcerans_Agy99 TERTFFRHFPTKEAVLFQDYENQLEWLARALAQRPVSEPLFDAVLASVAA
MSMEG_5673|M.smegmatis_MC2_155 SARTFSRYFATKDAVMLAFLDDVVDLVAGELAQQPPELGELDAVFCAHIT
TH_4253|M.thermoresistible__bu SPRTFSRYFATKDAVIVTLLDENLDQGARALREQPADMNHYDALFCAYRL
MLBr_02568|M.leprae_Br4923 SKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIV
: . :: *: : .
Mflv_5173|M.gilvum_PYR-GCK VFADLTPEEREDAAAGQRMMYGIPEARG-LIYSEYIRLIEMIAEAMVSRP
Mvan_1156|M.vanbaalenii_PYR-1 VFDGLTQEERDDFVAGEQMMYAIPEARG-LVYTEYVRLIDLIADALTDRP
MAV_4894|M.avium_104 VLSQLPDDQLEFESTRQRLMFSIPELKA-AMYDEYYRTVTVAAEAIAHRI
Mb0710c|M.bovis_AF2122/97 FNTFDESETIRHRKRMR-VILQTPELQA-YSMTMYAGWREVIAKFVARRS
Rv0691c|M.tuberculosis_H37Rv FNTFDESETIRHRKRMR-VILQTPELQA-YSMTMYAGWREVIAKFVARRS
MAB_3837|M.abscessus_ATCC_1997 FNDFPVDETPRHRMRMR-MILEVPALQA-YSMLMYTGWRDVIAQFVARRS
MMAR_2812|M.marinum_M FP--HDLEVVRQAATARSELISADRIAN-HLRVVQSSFAQVLTAFVRDRY
MUL_2933|M.ulcerans_Agy99 FP--HDLEVVRQAATARSELISADRIAN-HLRVVQSSFAQVLTAFVRNRY
MSMEG_5673|M.smegmatis_MC2_155 AFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFRPAPLFEVLAKR
TH_4253|M.thermoresistible__bu FYARTKDAGPDDLTSDRVVAMTRIIMCSPTLRQAVGEFRPHAVNVALAER
MLBr_02568|M.leprae_Br4923 SFLRYIDANRASWIVMYIQAMSLPAFAQ-TVREARDQITELVAGLMRVGT
Mflv_5173|M.gilvum_PYR-GCK DAPA-AAEERRVIAGAIVGVLIATSH------ETPMPDTELENSLTILSK
Mvan_1156|M.vanbaalenii_PYR-1 DGPT-DEMERRVVAGAIVGVLIAASH------NNPFPEDVLLRSLEILGR
MAV_4894|M.avium_104 GRAA-DDFEVRVFAGALTGAMMAAFD------SAPTTPETIYRALDFMDA
Mb0710c|M.bovis_AF2122/97 GGKT-TDFMPQTVAWTMLGVALSAYEHWLR-DESVSLTEALGAAFDVVGA
Rv0691c|M.tuberculosis_H37Rv GGKT-TDFMPQTVAWTMLGVALSAYEHWLR-DESVSLTEALGAAFDVVGA
MAB_3837|M.abscessus_ATCC_1997 GTDP-GSLLPQTVAWTLLGVALAAYEQWLA-DESSKLTTLLGKGFDAAEV
MMAR_2812|M.marinum_M ADVANVDLVAEVAGATIAAALVVAVENWGRNGCAVDLGELVAASLDLVRS
MUL_2933|M.ulcerans_Agy99 ADVANVDLVAEVAGATIAAALVVAVENWGRYGCAEDLGELVAASLDLVRS
MSMEG_5673|M.smegmatis_MC2_155 MGVSADDRKIALIASLWNAIMTTALVQLVP--DVDWATVTVERIVNQMRT
TH_4253|M.thermoresistible__bu MAVDLEDSRLRLVSSVWDAIMWASQQDLGP--HTDWDTVTVDNLIERMEH
MLBr_02568|M.leprae_Br4923 RSSR-PDHEYEIMAGALVGAGEAMATRLTT--GDIAVDEAAELMINLFWH
. . .
Mflv_5173|M.gilvum_PYR-GCK RMAR--------------
Mvan_1156|M.vanbaalenii_PYR-1 RLT---------------
MAV_4894|M.avium_104 GMPLD-------------
Mb0710c|M.bovis_AF2122/97 GLDRLNQ-----------
Rv0691c|M.tuberculosis_H37Rv GLDRLNQ-----------
MAB_3837|M.abscessus_ATCC_1997 GLRALR------------
MMAR_2812|M.marinum_M GLAPLS------------
MUL_2933|M.ulcerans_Agy99 GLAPLS------------
MSMEG_5673|M.smegmatis_MC2_155 TYAEFLEVAGRRHEFA--
TH_4253|M.thermoresistible__bu TYRQFVAQASAIGRPV--
MLBr_02568|M.leprae_Br4923 GLKGAPADRDFGPSIVAG