For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
IELDALTKVFGSGRDGRAPAVDGLTCTIEPGVVTGFLGPNGAGKTTTMRMILGLDRPTSGTATIDGRTYR QLAEPLRTVGALLDAKQVHPNRTVRNHLRWIAATHRIASRRVDDVVDMVGLSAVAGSRAGTLSLGMSQRL GIAAALIGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLAAEGRTVLVSSHLLAEMAETADRLVVIGRGRLI ASTTVAEFIGGADGAAVRVRSPRLDDLAAALAAAGMAVVRDGAALTVRHTTTDAVGELAATHSIPLHELT GQQVSLEQAYLAVTDDATEYRGRTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0193 | - | - | 100% (306) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_4301 | - | 2e-44 | 47.85% (209) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_1936 | - | 1e-32 | 33.78% (299) | daunorubicin resistance ABC transporter ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2707c | - | 4e-27 | 30.37% (270) | antibiotic ABC transporter ATP-binding protein |
| M. tuberculosis H37Rv | Rv2688c | - | 4e-27 | 30.37% (270) | antibiotic ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 1e-25 | 35.42% (240) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4215c | - | 1e-106 | 64.08% (309) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3263 | - | 2e-33 | 32.65% (294) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3250 | - | 1e-31 | 33.23% (310) | daunorubicin resistance ATP-binding protein DrrA |
| M. smegmatis MC2 155 | MSMEG_0795 | - | 1e-115 | 69.41% (304) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_2788 | - | 1e-120 | 73.38% (308) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_3577 | - | 2e-32 | 31.63% (294) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0712 | - | 1e-136 | 81.70% (306) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0193|M.gilvum_PYR-GCK ----------------MIELDALTKVFGSGRDGRAPAVDGLTCTIEPGVV
Mvan_0712|M.vanbaalenii_PYR-1 ----------------MIELRALTKTYRSVR-----AVDGLTATIEPGVV
MSMEG_0795|M.smegmatis_MC2_155 ----------------MIELAGLTKLYGTHR-----AVDDLSFTVEPGVV
TH_2788|M.thermoresistible__bu ------------MMAAMIELTALTKVFGRTR-----AVDDLTCTVEPGVV
MAB_4215c|M.abscessus_ATCC_199 ----------------MIELRSLTKVYGQTP-----AVDDLSVTIESGVV
MMAR_3263|M.marinum_M ----------MRRSQSAVEVIDLVKRRG-SVT----AVDGISFAVPPGGV
MUL_3577|M.ulcerans_Agy99 ----------MRRSQSAVEVIDLVKRRG-SVT----AVDGISFAVPQGGI
MAV_3250|M.avium_104 ------------MSAPAIEVEGLTKKFGGSTL----ALAGVDFSVPAGTV
Mb2707c|M.bovis_AF2122/97 MTALNRAVASARVGTEVIRVRGLTFRYPKAAEP---AVRGMEFTVGRGEI
Rv2688c|M.tuberculosis_H37Rv MTALNRAVASARVGTEVIRVRGLTFRYPKAAEP---AVRGMEFTVGRGEI
MLBr_00590|M.leprae_Br4923 ---MSSACTVPETPEVVIRLRGVCKHY--GSIL---AVSNLDLDIHSAEV
:.: : *: .: : . :
Mflv_0193|M.gilvum_PYR-GCK TGFLGPNGAGKTTTMRMILGLDRPTSGTATIDGRTYRQLAEPLR-TVGAL
Mvan_0712|M.vanbaalenii_PYR-1 TGFLGPNGAGKTTTMRIILGLDHPTSGTATIDGKTYRQLRNPLR-TVGAL
MSMEG_0795|M.smegmatis_MC2_155 TGFLGPNGAGKTTTMRLILGLDHPTSGTATIDGKRYRELKNPLR-TVGAL
TH_2788|M.thermoresistible__bu TGFLGPNGAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TVGAL
MAB_4215c|M.abscessus_ATCC_199 TGFLGPNGAGKSTTLRMIVGLARPTSGTATIGGKQYHEIDHPLR-EVGAL
MMAR_3263|M.marinum_M LGLLGPNGAGKTTTVRMLATLTRPTSGAAWVAGHDVCAAPESVRREIGLT
MUL_3577|M.ulcerans_Agy99 LGLLGPNGAGKTTTVRMVATLTRPTSGTAWVAGHDVCTAPESVRREIGLT
MAV_3250|M.avium_104 CGLLGHNGAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVRASIGMA
Mb2707c|M.bovis_AF2122/97 FGLLGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVS
Rv2688c|M.tuberculosis_H37Rv FGLLGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVS
MLBr_00590|M.leprae_Br4923 LALLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVM
.:** .****:** .: : : .* : . :*
Mflv_0193|M.gilvum_PYR-GCK LDAKQVHPNRTVRNHLRWIAATHRIA----SRRVDDVVDMVGLSAVAGSR
Mvan_0712|M.vanbaalenii_PYR-1 LDARQIHPNRTARNHLRWIAATNGIG----ATRPDEVLEMVGLTAVAGSR
MSMEG_0795|M.smegmatis_MC2_155 LDARQAHPNRSARSHLRWIAAANRIP----ASRVDEVLEMVGLASAADRN
TH_2788|M.thermoresistible__bu LDARAVHPARSARNHLRWLAAANRIP----QRRVDEVLELVGLTAVAARP
MAB_4215c|M.abscessus_ATCC_199 LDPKQFHPNRSARNHLRWIAAANDIS----AQRVDEVLEMVGLTEVANRH
MMAR_3263|M.marinum_M CQEATLDGLLTARENINMIGSLRGIRRKELASLTDRLLDQFSIAEFADRR
MUL_3577|M.ulcerans_Agy99 CQEATLDGLLTARENINMIGSLRGIRRKELASLSDRLLDQFSIAEFADRR
MAV_3250|M.avium_104 GQFTGMDPMLTGRENLVLFGRLRGLNRRRAKARADELLEQFNLVDAADRR
Mb2707c|M.bovis_AF2122/97 FELPNHYQKLTGYENLRFFASLYAGAT----ADPMQLLAAVGLADDAHTL
Rv2688c|M.tuberculosis_H37Rv FELPNHYQKLTGYENLRFFASLYAGAT----ADPMQLLAAVGLADDAHTL
MLBr_00590|M.leprae_Br4923 LQGGGGYPAARAGEMLNLVAS-YAADP----LDPEWLLETLGLTDVARTT
: . : .. :: ..: *
Mflv_0193|M.gilvum_PYR-GCK AGTLSLGMSQRLGIAAALIGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLA
Mvan_0712|M.vanbaalenii_PYR-1 AGTLSLGMSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLA
MSMEG_0795|M.smegmatis_MC2_155 AGALSLGMSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRELA
TH_2788|M.thermoresistible__bu AGTLSLGMSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMRTMA
MAB_4215c|M.abscessus_ATCC_199 AGTFSLGMSQRLGIAVALLGDPKVLLFDEPVNGLDPEGIHWIRTLMQSLA
MMAR_3263|M.marinum_M VDTYSGGMRRRLDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLRTLV
MUL_3577|M.ulcerans_Agy99 VDTYSGGMRRRLDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLGTLV
MAV_3250|M.avium_104 LSTYSGGMYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVSSLR
Mb2707c|M.bovis_AF2122/97 VGKYSKGMQMRLTFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLK
Rv2688c|M.tuberculosis_H37Rv VGKYSKGMQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLK
MLBr_00590|M.leprae_Br4923 YRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLR
* * *: .* :*: * ::::***. *:*. : :: :
Mflv_0193|M.gilvum_PYR-GCK AEGRTVLVSSHLLAEMAETADRLVVIGRGRLIASTTVAEFIGGADGAAVR
Mvan_0712|M.vanbaalenii_PYR-1 GEGRTVLVSSHLLSEMANTADRLVVIGRGRLIASTTVTEFIGRSGGAVVR
MSMEG_0795|M.smegmatis_MC2_155 GEGRTVFVSSHLLAEMANTADRLVVIGQGKLIASTTVTEFVNGSDADTVR
TH_2788|M.thermoresistible__bu AEGRTVLVSSHLLAEMANTADRLLVIGRGRLIASTSVAEFVGSTAAERVR
MAB_4215c|M.abscessus_ATCC_199 AQGRTVLVSSHLLSEMANTADQLVVIGRGRLIAATSMHEFVSRAGADVVR
MMAR_3263|M.marinum_M DDGLTLVLTTQYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIV
MUL_3577|M.ulcerans_Agy99 DDGPTLVLTTQYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIV
MAV_3250|M.avium_104 VQGISVLLTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTSYCQ
Mb2707c|M.bovis_AF2122/97 ARGRTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVR
Rv2688c|M.tuberculosis_H37Rv ARGRTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVR
MLBr_00590|M.leprae_Br4923 RDGVTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLR
* ::.:::: : .* : .: *:::* : *:
Mflv_0193|M.gilvum_PYR-GCK VRSPRLDDLAAALAAAGMAVVR-----DGAALTVRH----TTTDAVGELA
Mvan_0712|M.vanbaalenii_PYR-1 VRSPRLRDLRTVLAAAGLAVRE-----DGASLTVHD----TTTEAVGELA
MSMEG_0795|M.smegmatis_MC2_155 VRSPQLETLRDVLSDAGLDVVTEP---DGGALNVHG----VAIEVIGDLA
TH_2788|M.thermoresistible__bu VRSPEMDTLRGLLADAGVEVRLEP---DGAALTVRG----AAPEVVGELA
MAB_4215c|M.abscessus_ATCC_199 VRSPQIDILRSAAEESGFSVVGGERTGEPGVLEISG----ALIEQVGELA
MMAR_3263|M.marinum_M VTVSRTEDVANVAAFLRTGAKEVRVDISARRITVAT-HGLLDLSDVARML
MUL_3577|M.ulcerans_Agy99 VTVSRTEDVANVAAFLRTGVKEVRVDICARRITVAT-HGLLDLSEVARML
MAV_3250|M.avium_104 VTPANPAELPQVAAAL-TGLEGIEIDSDTGSVSVFAPDGVATLVEVFRRV
Mb2707c|M.bovis_AF2122/97 VEYRG---------------DGGGL--ETAEFGMDGLADDPAFHSVLR--
Rv2688c|M.tuberculosis_H37Rv VEYRG---------------DGGGL--ETAEFGMDGLADDPAFHSVLR--
MLBr_00590|M.leprae_Br4923 FSAPPRLDLSLLAFALPEDYKTTEL--TPGEYLVAGPIDPQVLATVTAWC
. : :
Mflv_0193|M.gilvum_PYR-GCK ATHSIPLHELTGQQVSLEQAYLAVTDDATEYRGRTR--------------
Mvan_0712|M.vanbaalenii_PYR-1 AAHSIALHELSSQQVSLEQAYLASTDDATEYRGTPR--------------
MSMEG_0795|M.smegmatis_MC2_155 ARNAITLHELSRRQASLEEAYLKLTDDAVDYRAVQP--------------
TH_2788|M.thermoresistible__bu ARNGITLHELSVQRASLEDAYLELTDAAVEYRAVPR--------------
MAB_4215c|M.abscessus_ATCC_199 ARRGVTLYELSPQRVSLEDAYLSLTDDAVQYRSQVNDPLAARATGAVADA
MMAR_3263|M.marinum_M HQYAAPIEDIRLTRPSLDDVFVLLTGHHGSSSEGD------------SA-
MUL_3577|M.ulcerans_Agy99 HHYAAPVEDIRLARPSLDDVFVLLTGHHSSSSEGDGRLGAWPALVAGSAE
MAV_3250|M.avium_104 DALGLELADISLRKPSLDEAFLHLTERTVARS------------------
Mb2707c|M.bovis_AF2122/97 ---NHHVETIHSREASLDDVFVEVTGRQLT--------------------
Rv2688c|M.tuberculosis_H37Rv ---NHHVETIHSREASLDDVFVEVTGRQLT--------------------
MLBr_00590|M.leprae_Br4923 AQINVLTTNMRVEQHSLEDVFLDLTGRKLR--------------------
: . **::.:: *
Mflv_0193|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0712|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0795|M.smegmatis_MC2_155 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 EGTH----------------------------------------------
MMAR_3263|M.marinum_M --------------------------------------------------
MUL_3577|M.ulcerans_Agy99 HARGVRSCARSGRGVLWRSSTLHQLCCGETGNRLARVRWGWRVGLSAGLR
MAV_3250|M.avium_104 --------------------------------------------------
Mb2707c|M.bovis_AF2122/97 --------------------------------------------------
Rv2688c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
Mflv_0193|M.gilvum_PYR-GCK -----------------------------
Mvan_0712|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_0795|M.smegmatis_MC2_155 -----------------------------
TH_2788|M.thermoresistible__bu -----------------------------
MAB_4215c|M.abscessus_ATCC_199 -----------------------------
MMAR_3263|M.marinum_M -----------------------------
MUL_3577|M.ulcerans_Agy99 RRTRRGRRAPRNRAASTGLGGLTRVRRRW
MAV_3250|M.avium_104 -----------------------------
Mb2707c|M.bovis_AF2122/97 -----------------------------
Rv2688c|M.tuberculosis_H37Rv -----------------------------
MLBr_00590|M.leprae_Br4923 -----------------------------