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TALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGLLGPSGAGKSTTQKLLIGLLRD HGGQATVWDKEPAEWGPDYYERIGVSFELPNHYQKLTGYENLRFFASLYAGATADPMQLLAAVGLADDAH TLVGKYSKGMQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARGRTIFLTTHDMATADE LCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEYRGDGGGLETAEFGMDGLADDPAFHSVLRNHHVETI HSREASLDDVFVEVTGRQLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2688c | - | - | 100% (301) | PROBABLE ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv1458c | - | 1e-31 | 32.49% (317) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. tuberculosis H37Rv | Rv1218c | - | 2e-27 | 32.91% (237) | tetronasin-transport ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2707c | - | 1e-172 | 99.67% (301) | antibiotic ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_1936 | - | 3e-33 | 34.35% (294) | daunorubicin resistance ABC transporter ATPase subunit |
| M. leprae Br4923 | MLBr_00590 | - | 6e-34 | 32.35% (306) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1858 | - | 1e-128 | 77.97% (286) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2026 | - | 1e-133 | 79.45% (292) | antibiotic-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3321 | - | 9e-33 | 31.48% (305) | ABC transporter, ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_1502 | - | 1e-134 | 80.77% (286) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_2788 | - | 1e-24 | 29.86% (278) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_1859 | - | 4e-32 | 32.89% (304) | antibiotic ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_0776 | - | 1e-130 | 80.63% (284) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2688c|M.tuberculosis_H37Rv MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
Mb2707c|M.bovis_AF2122/97 MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
MSMEG_1502|M.smegmatis_MC2_155 ----------MGSASEVIDVRDLTFTYPRAAEPAVRGMDFAVGNGEIFGF
Mvan_0776|M.vanbaalenii_PYR-1 ----------MNTES-VIDVRDLTYTYPKTAEPAVRGMDFAVGRGEIFGF
MMAR_2026|M.marinum_M --MRDPEPAVSGAVGEVIRVRGLTFAYPKASTPAVRGMDFSVGRGEIFGF
MAB_1858|M.abscessus_ATCC_1997 -------------MTEVIQVRELTFTYPKTPEPAVRGMDFTVGEGEIFGF
MAV_3321|M.avium_104 -----------------MRLRGVSKHYG--STTAVRDLDLEVHAAEVLAL
MUL_1859|M.ulcerans_Agy99 ----------------MVRLRGVGKQYG--SVTAVSNLDLEVRAAEVMAL
MLBr_00590|M.leprae_Br4923 ---MSSACTVPETPEVVIRLRGVCKHYG--SILAVSNLDLDIHSAEVLAL
Mflv_1936|M.gilvum_PYR-GCK -----------MPFPPAIEALDLVKRFG--DQTAVAGVSFVVPPGTVLGL
TH_2788|M.thermoresistible__bu ------------MMAAMIELTALTKVFG--RTRAVDDLTCTVEPGVVTGF
: : : ** .: : . : .:
Rv2688c|M.tuberculosis_H37Rv LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
Mb2707c|M.bovis_AF2122/97 LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
MSMEG_1502|M.smegmatis_MC2_155 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPVDWGQDYYQRVGVSFEL
Mvan_0776|M.vanbaalenii_PYR-1 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPLDWGPRYYQRIGVSFEL
MMAR_2026|M.marinum_M LGPSGAGKSTTQRILIGLLRGHGGEVAVWGKDPASWGSDYYERIGVSFEL
MAB_1858|M.abscessus_ATCC_1997 LGPSGAGKSTTQKLLIGLLRGHGGRATVWGREPGAWGRNYYQRIGVSFEL
MAV_3321|M.avium_104 LGPNGAGKTTTVEMCEGFVRPDAGTLEVLGLDPIADNARLRPRIGVMLQG
MUL_1859|M.ulcerans_Agy99 LGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQG
MLBr_00590|M.leprae_Br4923 LGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQG
Mflv_1936|M.gilvum_PYR-GCK LGPNGAGKTTTVRMMTTLTEPTSGTARVAGFDVRTHPDEVRRHMGLTGQV
TH_2788|M.thermoresistible__bu LGPNGAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TVGALLDA
***.****:** .: : . .* : . :* :
Rv2688c|M.tuberculosis_H37Rv PNHYQKLTGYENLRFFASLYAGATADPM----QLLAAVGLADDAHTLVGK
Mb2707c|M.bovis_AF2122/97 PNHYQKLTGYENLRFFASLYAGATADPM----QLLAAVGLADDAHTLVGK
MSMEG_1502|M.smegmatis_MC2_155 PNHYLRLTGLENLQFFASLYEKQTEDPM----ELLHAVGLADAAYTRVGE
Mvan_0776|M.vanbaalenii_PYR-1 PNHYLKLTGAENLQFFASLYDSAGPDPR----SLLDDVGLTDAADTRVAK
MMAR_2026|M.marinum_M PNHYQKLTGLENLQFFASLYSAPTLDPM----QLLEAVGLADHADTRAGK
MAB_1858|M.abscessus_ATCC_1997 PNHYQKLTALENLRFFASLYAGPTRDPM----ELLDAVGLADDANTRVGA
MAV_3321|M.avium_104 GGGYPAARAGEMLNLVAAYAADP-LDPA----WLLDTLGLTDAARTTYRR
MUL_1859|M.ulcerans_Agy99 GGGYPAARAGEMLDLVASYAADP-LDPR----WLLDTLGLTDAARTTYRR
MLBr_00590|M.leprae_Br4923 GGGYPAARAGEMLNLVASYAADP-LDPE----WLLETLGLTDVARTTYRR
Mflv_1936|M.gilvum_PYR-GCK ATVDELLTGRENIRMIGGLYGIRRRDLKNLGDQLLHQFSLTDAADRPVRS
TH_2788|M.thermoresistible__bu RAVHPARSARNHLRWLAAANRIPQR----RVDEVLELVGLTAVAARPAGT
. : : ... :* ..*: *
Rv2688c|M.tuberculosis_H37Rv YSKGMQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARG
Mb2707c|M.bovis_AF2122/97 YSKGMQMRLTFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARG
MSMEG_1502|M.smegmatis_MC2_155 YSKGMQMRLTFARSLINKPELLFLDEPTSGLDPVNARRVKEIVLDLKSKG
Mvan_0776|M.vanbaalenii_PYR-1 YSKGMQMRLTFARSLVNDPELLFLDEPTSGLDPVNARRIKDIILDLKARG
MMAR_2026|M.marinum_M YSKGMQMRLTFARALLNDPELLFLDEPTSGMDPVNARSVKNMIMDLKARG
MAB_1858|M.abscessus_ATCC_1997 FSKGMQMRLTFVRALINDPELLFLDEPTSGLDPVNARKVKDMVLELKARG
MAV_3321|M.avium_104 LSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDG
MUL_1859|M.ulcerans_Agy99 LSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDG
MLBr_00590|M.leprae_Br4923 LSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDG
Mflv_1936|M.gilvum_PYR-GCK YSGGMRRRLDLAVSLLASPPVLFLDEPTTGLDPRSRSELWDVLRGLVAQG
TH_2788|M.thermoresistible__bu LSLGMSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMRTMAAEG
* * ** :. :*: * ::::***. *:*. : :: : *
Rv2688c|M.tuberculosis_H37Rv RTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEY
Mb2707c|M.bovis_AF2122/97 RTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEY
MSMEG_1502|M.smegmatis_MC2_155 RTIFLTTHDMSTADELCDRIAFVVDGSIVALDTPAELKIARSRRRVRVQY
Mvan_0776|M.vanbaalenii_PYR-1 RTVFLTTHDMATADELCDRVAFVVDGRIVALDAPAELKIARSRRLVRVEY
MMAR_2026|M.marinum_M RTVFLTTHDMATADELCDRVAFVVDGSIVVSDRPAELKIARSQRLVTVEY
MAB_1858|M.abscessus_ATCC_1997 RTIFITTHAMSAADELCDRVAFVVDGRIVAMNSPAELKLEYGRRSVRVEY
MAV_3321|M.avium_104 VTVVLTTHQLKEAEELADRLVIIDHGATVAAGTPAELMRSGAKDQLRFSA
MUL_1859|M.ulcerans_Agy99 VTVVLTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLRFTA
MLBr_00590|M.leprae_Br4923 VTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSA
Mflv_1936|M.gilvum_PYR-GCK TTLLLTTQYLEEADQLADNIVVIDRGRIIAEGSPLHLKQQAGRASLVVTV
TH_2788|M.thermoresistible__bu RTVLVSSHLLAEMANTADRLLVIGRGRLIASTS---VAEFVGSTAAERVR
*:.:::: : : .*.: .: * :. : .
Rv2688c|M.tuberculosis_H37Rv RG---------------DGGGLETAEFGMDGLADDPAFHSVLR------N
Mb2707c|M.bovis_AF2122/97 RG---------------DGGGLETAEFGMDGLADDPAFHSVLR------N
MSMEG_1502|M.smegmatis_MC2_155 RV---------------ADGGLRTAEFGMDGLADDPEFHAVLR------D
Mvan_0776|M.vanbaalenii_PYR-1 RS---------------AQGTLQTTEFPMDGLADDPEFRTVLR------D
MMAR_2026|M.marinum_M RG---------------NGGGLSAAEFSLDTLADDPAFHAVLR------E
MAB_1858|M.abscessus_ATCC_1997 RG---------------AAGELAGQDFPLDGLADNDAFHAVLR------G
MAV_3321|M.avium_104 PPRLDLSLLSAALPEDYKATELTPGEYLVEGPVDPQVLATVTAWCAR-ID
MUL_1859|M.ulcerans_Agy99 PPRLDLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCAR-ID
MLBr_00590|M.leprae_Br4923 PPRLDLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQ-IN
Mflv_1936|M.gilvum_PYR-GCK ADAADLESARGLLARTGAEVYVDAGARRLTATADGLDDMVKVAGWLRDSG
TH_2788|M.thermoresistible__bu VRSPEMDTLRGLLADAGVEVRLEPDGAALTVRGAAPEVVGELAARN---G
: :
Rv2688c|M.tuberculosis_H37Rv HHVETIHSREASLDDVFVEVTGRQLT-------
Mb2707c|M.bovis_AF2122/97 HHVETIHSREASLDDVFVEVTGRQLT-------
MSMEG_1502|M.smegmatis_MC2_155 HHVETIHSREASLDDVFVEVTGRQLA-------
Mvan_0776|M.vanbaalenii_PYR-1 HHVETIHSREASLDEVFVDVTGRSLA-------
MMAR_2026|M.marinum_M HQVETIHSREASLEDVFVEVTGRRLS-------
MAB_1858|M.abscessus_ATCC_1997 HHVETIHSEEASLDDVFVAVTGRRLA-------
MAV_3321|M.avium_104 VLATDMRVEQRSLEDVFLDLTGRKLRQ------
MUL_1859|M.ulcerans_Agy99 VLATDMRVEQRSLEDVFLDLTGRKLRS------
MLBr_00590|M.leprae_Br4923 VLTTNMRVEQHSLEDVFLDLTGRKLR-------
Mflv_1936|M.gilvum_PYR-GCK ITVDDIGLSRPSLDDVFLMLTGHRTDDTEEVGA
TH_2788|M.thermoresistible__bu ITLHELSVQRASLEDAYLELTDAAVEYRAVPR-
: . **::.:: :*.