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IELRSLTKVYGQTPAVDDLSVTIESGVVTGFLGPNGAGKSTTLRMIVGLARPTSGTATIGGKQYHEIDHP LREVGALLDPKQFHPNRSARNHLRWIAAANDISAQRVDEVLEMVGLTEVANRHAGTFSLGMSQRLGIAVA LLGDPKVLLFDEPVNGLDPEGIHWIRTLMQSLAAQGRTVLVSSHLLSEMANTADQLVVIGRGRLIAATSM HEFVSRAGADVVRVRSPQIDILRSAAEESGFSVVGGERTGEPGVLEISGALIEQVGELAARRGVTLYELS PQRVSLEDAYLSLTDDAVQYRSQVNDPLAARATGAVADAEGTH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4215c | - | - | 100% (324) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1858 | - | 5e-34 | 31.21% (298) | antibiotic ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1689 | - | 1e-29 | 31.79% (302) | daunorubicin resistance ABC transporter ATP-binding subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1493c | - | 8e-30 | 32.13% (305) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_0193 | - | 1e-106 | 64.08% (309) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1458c | - | 9e-30 | 32.13% (305) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00590 | - | 2e-32 | 33.11% (305) | putative ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3263 | - | 5e-35 | 32.26% (310) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3250 | - | 2e-33 | 32.69% (309) | daunorubicin resistance ATP-binding protein DrrA |
| M. smegmatis MC2 155 | MSMEG_0795 | - | 1e-114 | 67.99% (303) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_2788 | - | 1e-112 | 68.65% (303) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_3577 | - | 4e-35 | 31.61% (310) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0712 | - | 1e-109 | 67.22% (302) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0795|M.smegmatis_MC2_155 -------MIELAGLTKLYGTHR-------AVDDLSFTVEPGVVTGFLGPN
TH_2788|M.thermoresistible__bu ---MMAAMIELTALTKVFGRTR-------AVDDLTCTVEPGVVTGFLGPN
Mflv_0193|M.gilvum_PYR-GCK -------MIELDALTKVFGSGRDGR--APAVDGLTCTIEPGVVTGFLGPN
Mvan_0712|M.vanbaalenii_PYR-1 -------MIELRALTKTYRSVR-------AVDGLTATIEPGVVTGFLGPN
MAB_4215c|M.abscessus_ATCC_199 -------MIELRSLTKVYGQTP-------AVDDLSVTIESGVVTGFLGPN
Mb1493c|M.bovis_AF2122/97 MN---RAPDTPEVVLRLRGVCKRYG-SITAVSNLDLDVHDAEVMALLGPN
Rv1458c|M.tuberculosis_H37Rv MN---RAPDTPEVVLRLRGVCKRYG-SITAVSNLDLDVHDAEVMALLGPN
MLBr_00590|M.leprae_Br4923 MSSACTVPETPEVVIRLRGVCKHYG-SILAVSNLDLDIHSAEVLALLGPN
MMAR_3263|M.marinum_M -------MRRSQSAVEVIDLVKRRG-SVTAVDGISFAVPPGGVLGLLGPN
MUL_3577|M.ulcerans_Agy99 -------MRRSQSAVEVIDLVKRRG-SVTAVDGISFAVPQGGILGLLGPN
MAV_3250|M.avium_104 ---------MSAPAIEVEGLTKKFGGSTLALAGVDFSVPAGTVCGLLGHN
. *: .: : . : .:** *
MSMEG_0795|M.smegmatis_MC2_155 GAGKTTTMRLILGLDHPTSGTATIDGKRYRELKNPLR-TVGALLDARQAH
TH_2788|M.thermoresistible__bu GAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TVGALLDARAVH
Mflv_0193|M.gilvum_PYR-GCK GAGKTTTMRMILGLDRPTSGTATIDGRTYRQLAEPLR-TVGALLDAKQVH
Mvan_0712|M.vanbaalenii_PYR-1 GAGKTTTMRIILGLDHPTSGTATIDGKTYRQLRNPLR-TVGALLDARQIH
MAB_4215c|M.abscessus_ATCC_199 GAGKSTTLRMIVGLARPTSGTATIGGKQYHEIDHPLR-EVGALLDPKQFH
Mb1493c|M.bovis_AF2122/97 GAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGY
Rv1458c|M.tuberculosis_H37Rv GAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGY
MLBr_00590|M.leprae_Br4923 GAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQGGGGY
MMAR_3263|M.marinum_M GAGKTTTVRMLATLTRPTSGAAWVAGHDVCAAPESVRREIGLTCQEATLD
MUL_3577|M.ulcerans_Agy99 GAGKTTTVRMVATLTRPTSGTAWVAGHDVCTAPESVRREIGLTCQEATLD
MAV_3250|M.avium_104 GAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVRASIGMAGQFTGMD
****:**:.: : :* :* : * :* :* :
MSMEG_0795|M.smegmatis_MC2_155 PNRSARSHLRWIAAANRIP----ASRVDEVLEMVGLASAADRNAGALSLG
TH_2788|M.thermoresistible__bu PARSARNHLRWLAAANRIP----QRRVDEVLELVGLTAVAARPAGTLSLG
Mflv_0193|M.gilvum_PYR-GCK PNRTVRNHLRWIAATHRIA----SRRVDDVVDMVGLSAVAGSRAGTLSLG
Mvan_0712|M.vanbaalenii_PYR-1 PNRTARNHLRWIAATNGIG----ATRPDEVLEMVGLTAVAGSRAGTLSLG
MAB_4215c|M.abscessus_ATCC_199 PNRSARNHLRWIAAANDIS----AQRVDEVLEMVGLTEVANRHAGTFSLG
Mb1493c|M.bovis_AF2122/97 PAARAGEMLDLVASYAAN-----PLDPHWLLDTLGLTEAARTTYRRLSGG
Rv1458c|M.tuberculosis_H37Rv PAARAGEMLDLVASYAAN-----PLDPHWLLDTLGLTEAARTTYRRLSGG
MLBr_00590|M.leprae_Br4923 PAARAGEMLNLVASYAAD-----PLDPEWLLETLGLTDVARTTYRRLSGG
MMAR_3263|M.marinum_M GLLTARENINMIGSLRGIRRKELASLTDRLLDQFSIAEFADRRVDTYSGG
MUL_3577|M.ulcerans_Agy99 GLLTARENINMIGSLRGIRRKELASLSDRLLDQFSIAEFADRRVDTYSGG
MAV_3250|M.avium_104 PMLTGRENLVLFGRLRGLNRRRAKARADELLEQFNLVDAADRRLSTYSGG
. : .. . ::: ..: * * *
MSMEG_0795|M.smegmatis_MC2_155 MSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRELAGEGRTVF
TH_2788|M.thermoresistible__bu MSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMRTMAAEGRTVL
Mflv_0193|M.gilvum_PYR-GCK MSQRLGIAAALIGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLAAEGRTVL
Mvan_0712|M.vanbaalenii_PYR-1 MSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLAGEGRTVL
MAB_4215c|M.abscessus_ATCC_199 MSQRLGIAVALLGDPKVLLFDEPVNGLDPEGIHWIRTLMQSLAAQGRTVL
Mb1493c|M.bovis_AF2122/97 QQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVV
Rv1458c|M.tuberculosis_H37Rv QQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVV
MLBr_00590|M.leprae_Br4923 QQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVV
MMAR_3263|M.marinum_M MRRRLDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLRTLVDDGLTLV
MUL_3577|M.ulcerans_Agy99 MRRRLDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLGTLVDDGPTLV
MAV_3250|M.avium_104 MYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVSSLRVQGISVL
:*: :* :*: * ::::***. *:*... : :: : :* ::.
MSMEG_0795|M.smegmatis_MC2_155 VSSHLLAEMANTADRLVVIGQGKLIASTTVTEFVNGSDADTVRVRSPQLE
TH_2788|M.thermoresistible__bu VSSHLLAEMANTADRLLVIGRGRLIASTSVAEFVGSTAAERVRVRSPEMD
Mflv_0193|M.gilvum_PYR-GCK VSSHLLAEMAETADRLVVIGRGRLIASTTVAEFIGGADGAAVRVRSPRLD
Mvan_0712|M.vanbaalenii_PYR-1 VSSHLLSEMANTADRLVVIGRGRLIASTTVTEFIGRSGGAVVRVRSPRLR
MAB_4215c|M.abscessus_ATCC_199 VSSHLLSEMANTADQLVVIGRGRLIAATSMHEFVSRAGADVVRVRSPQID
Mb1493c|M.bovis_AF2122/97 LTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRL
Rv1458c|M.tuberculosis_H37Rv LTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRL
MLBr_00590|M.leprae_Br4923 LTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRL
MMAR_3263|M.marinum_M LTTQYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIVVTVSRTE
MUL_3577|M.ulcerans_Agy99 LTTQYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIVVTVSRTE
MAV_3250|M.avium_104 LTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTSYCQVTPANPA
:::: * * :* :::*.:* :* : *: . .
MSMEG_0795|M.smegmatis_MC2_155 TLRDVLSDAGLDVVTEP---DGGALNVHG----VAIEVIGDLAARNAITL
TH_2788|M.thermoresistible__bu TLRGLLADAGVEVRLEP---DGAALTVRG----AAPEVVGELAARNGITL
Mflv_0193|M.gilvum_PYR-GCK DLAAALAAAGMAVVR-----DGAALTVRH----TTTDAVGELAATHSIPL
Mvan_0712|M.vanbaalenii_PYR-1 DLRTVLAAAGLAVRE-----DGASLTVHD----TTTEAVGELAAAHSIAL
MAB_4215c|M.abscessus_ATCC_199 ILRSAAEESGFSVVGGERTGEPGVLEISG----ALIEQVGELAARRGVTL
Mb1493c|M.bovis_AF2122/97 DLSLLASALPEGYQATELTP--GEYLVEGPVDPQVLATVTAWCAQIDVLA
Rv1458c|M.tuberculosis_H37Rv DLSLLASALPEGYQATELTP--GEYLVEGPVDPQVLATVTAWCAQIDVLA
MLBr_00590|M.leprae_Br4923 DLSLLAFALPEDYKTTELTP--GEYLVAGPIDPQVLATVTAWCAQINVLT
MMAR_3263|M.marinum_M DVANVAAFLRTGAKEVRVDISARRITVAT-HGLLDLSDVARMLHQYAAPI
MUL_3577|M.ulcerans_Agy99 DVANVAAFLRTGVKEVRVDICARRITVAT-HGLLDLSEVARMLHHYAAPV
MAV_3250|M.avium_104 ELPQVAAAL-TGLEGIEIDSDTGSVSVFAPDGVATLVEVFRRVDALGLEL
: : :
MSMEG_0795|M.smegmatis_MC2_155 HELSRRQASLEEAYLKLTDDAVDYRAVQP---------------------
TH_2788|M.thermoresistible__bu HELSVQRASLEDAYLELTDAAVEYRAVPR---------------------
Mflv_0193|M.gilvum_PYR-GCK HELTGQQVSLEQAYLAVTDDATEYRGRTR---------------------
Mvan_0712|M.vanbaalenii_PYR-1 HELSSQQVSLEQAYLASTDDATEYRGTPR---------------------
MAB_4215c|M.abscessus_ATCC_199 YELSPQRVSLEDAYLSLTDDAVQYRSQVNDPLAARATGAVADAEGTH---
Mb1493c|M.bovis_AF2122/97 TDMRVEQRSLEDVFLDLTGRKLRQ--------------------------
Rv1458c|M.tuberculosis_H37Rv TDMRVEQRSLEDVFLDLTGRKLRQ--------------------------
MLBr_00590|M.leprae_Br4923 TNMRVEQHSLEDVFLDLTGRKLR---------------------------
MMAR_3263|M.marinum_M EDIRLTRPSLDDVFVLLTGHHGSSSEGD------------SA--------
MUL_3577|M.ulcerans_Agy99 EDIRLARPSLDDVFVLLTGHHSSSSEGDGRLGAWPALVAGSAEHARGVRS
MAV_3250|M.avium_104 ADISLRKPSLDEAFLHLTERTVARS-------------------------
:: : **::.:: *
MSMEG_0795|M.smegmatis_MC2_155 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mflv_0193|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0712|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1493c|M.bovis_AF2122/97 --------------------------------------------------
Rv1458c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MMAR_3263|M.marinum_M --------------------------------------------------
MUL_3577|M.ulcerans_Agy99 CARSGRGVLWRSSTLHQLCCGETGNRLARVRWGWRVGLSAGLRRRTRRGR
MAV_3250|M.avium_104 --------------------------------------------------
MSMEG_0795|M.smegmatis_MC2_155 ----------------------
TH_2788|M.thermoresistible__bu ----------------------
Mflv_0193|M.gilvum_PYR-GCK ----------------------
Mvan_0712|M.vanbaalenii_PYR-1 ----------------------
MAB_4215c|M.abscessus_ATCC_199 ----------------------
Mb1493c|M.bovis_AF2122/97 ----------------------
Rv1458c|M.tuberculosis_H37Rv ----------------------
MLBr_00590|M.leprae_Br4923 ----------------------
MMAR_3263|M.marinum_M ----------------------
MUL_3577|M.ulcerans_Agy99 RAPRNRAASTGLGGLTRVRRRW
MAV_3250|M.avium_104 ----------------------