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MIELAGLTKLYGTHRAVDDLSFTVEPGVVTGFLGPNGAGKTTTMRLILGLDHPTSGTATIDGKRYRELKN PLRTVGALLDARQAHPNRSARSHLRWIAAANRIPASRVDEVLEMVGLASAADRNAGALSLGMSQRLGIAA ALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRELAGEGRTVFVSSHLLAEMANTADRLVVIGQGKLIASTT VTEFVNGSDADTVRVRSPQLETLRDVLSDAGLDVVTEPDGGALNVHGVAIEVIGDLAARNAITLHELSRR QASLEEAYLKLTDDAVDYRAVQP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0795 | - | - | 100% (303) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5312 | - | 2e-54 | 48.50% (233) | ABC-type multidrug transport system ATPase component |
| M. smegmatis MC2 155 | MSMEG_4530 | cysA | 1e-29 | 36.41% (217) | sulfate ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2707c | - | 3e-28 | 28.09% (299) | antibiotic ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_0193 | - | 1e-116 | 69.41% (304) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2688c | - | 3e-28 | 28.09% (299) | antibiotic ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 8e-29 | 32.78% (299) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4215c | - | 1e-114 | 67.99% (303) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2026 | - | 4e-31 | 30.10% (299) | antibiotic-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3250 | - | 3e-32 | 34.49% (316) | daunorubicin resistance ATP-binding protein DrrA |
| M. thermoresistible (build 8) | TH_2788 | - | 1e-130 | 77.08% (301) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_3577 | - | 5e-29 | 29.97% (307) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0712 | - | 1e-123 | 75.25% (299) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0795|M.smegmatis_MC2_155 ----------------MIELAGLTKLYGTHR-----AVDDLSFTVEPGVV
TH_2788|M.thermoresistible__bu ------------MMAAMIELTALTKVFGRTR-----AVDDLTCTVEPGVV
Mflv_0193|M.gilvum_PYR-GCK ----------------MIELDALTKVFGSGRDGRAPAVDGLTCTIEPGVV
Mvan_0712|M.vanbaalenii_PYR-1 ----------------MIELRALTKTYRSVR-----AVDGLTATIEPGVV
MAB_4215c|M.abscessus_ATCC_199 ----------------MIELRSLTKVYGQTP-----AVDDLSVTIESGVV
MAV_3250|M.avium_104 ------------MSAPAIEVEGLTKKFGGSTL----ALAGVDFSVPAGTV
MUL_3577|M.ulcerans_Agy99 ----------MRRSQSAVEVIDLVKRRG-SVT----AVDGISFAVPQGGI
Mb2707c|M.bovis_AF2122/97 MTALNRAVASARVGTEVIRVRGLTFRYPKAAEP---AVRGMEFTVGRGEI
Rv2688c|M.tuberculosis_H37Rv MTALNRAVASARVGTEVIRVRGLTFRYPKAAEP---AVRGMEFTVGRGEI
MMAR_2026|M.marinum_M MRDPEPAVSGA-VG-EVIRVRGLTFAYPKASTP---AVRGMDFSVGRGEI
MLBr_00590|M.leprae_Br4923 ---MSSACTVPETPEVVIRLRGVCKHY--GSIL---AVSNLDLDIHSAEV
:.: : *: .: : . :
MSMEG_0795|M.smegmatis_MC2_155 TGFLGPNGAGKTTTMRLILGLDHPTSGTATIDGKRYRELKNPLR-TVGAL
TH_2788|M.thermoresistible__bu TGFLGPNGAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TVGAL
Mflv_0193|M.gilvum_PYR-GCK TGFLGPNGAGKTTTMRMILGLDRPTSGTATIDGRTYRQLAEPLR-TVGAL
Mvan_0712|M.vanbaalenii_PYR-1 TGFLGPNGAGKTTTMRIILGLDHPTSGTATIDGKTYRQLRNPLR-TVGAL
MAB_4215c|M.abscessus_ATCC_199 TGFLGPNGAGKSTTLRMIVGLARPTSGTATIGGKQYHEIDHPLR-EVGAL
MAV_3250|M.avium_104 CGLLGHNGAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVRASIGMA
MUL_3577|M.ulcerans_Agy99 LGLLGPNGAGKTTTVRMVATLTRPTSGTAWVAGHDVCTAPESVRREIGLT
Mb2707c|M.bovis_AF2122/97 FGLLGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVS
Rv2688c|M.tuberculosis_H37Rv FGLLGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVS
MMAR_2026|M.marinum_M FGFLGPSGAGKSTTQRILIGLLRGHGGEVAVWGKDPASWGSDYYERIGVS
MLBr_00590|M.leprae_Br4923 LALLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVM
.:** .****:** .: : : .* : . :*
MSMEG_0795|M.smegmatis_MC2_155 LDARQAHPNRSARSHLRWIAAANRIPAS----RVDEVLEMVGLASAADRN
TH_2788|M.thermoresistible__bu LDARAVHPARSARNHLRWLAAANRIPQR----RVDEVLELVGLTAVAARP
Mflv_0193|M.gilvum_PYR-GCK LDAKQVHPNRTVRNHLRWIAATHRIASR----RVDDVVDMVGLSAVAGSR
Mvan_0712|M.vanbaalenii_PYR-1 LDARQIHPNRTARNHLRWIAATNGIGAT----RPDEVLEMVGLTAVAGSR
MAB_4215c|M.abscessus_ATCC_199 LDPKQFHPNRSARNHLRWIAAANDISAQ----RVDEVLEMVGLTEVANRH
MAV_3250|M.avium_104 GQFTGMDPMLTGRENLVLFGRLRGLNRRRAKARADELLEQFNLVDAADRR
MUL_3577|M.ulcerans_Agy99 CQEATLDGLLTARENINMIGSLRGIRRKELASLSDRLLDQFSIAEFADRR
Mb2707c|M.bovis_AF2122/97 FELPNHYQKLTGYENLRFFASLYAGATA----DPMQLLAAVGLADDAHTL
Rv2688c|M.tuberculosis_H37Rv FELPNHYQKLTGYENLRFFASLYAGATA----DPMQLLAAVGLADDAHTL
MMAR_2026|M.marinum_M FELPNHYQKLTGLENLQFFASLYSAPTL----DPMQLLEAVGLADHADTR
MLBr_00590|M.leprae_Br4923 LQGGGGYPAARAGEMLNLVAS-YAADPL----DPEWLLETLGLTDVARTT
: . : .. :: ..: *
MSMEG_0795|M.smegmatis_MC2_155 AGALSLGMSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRELA
TH_2788|M.thermoresistible__bu AGTLSLGMSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMRTMA
Mflv_0193|M.gilvum_PYR-GCK AGTLSLGMSQRLGIAAALIGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLA
Mvan_0712|M.vanbaalenii_PYR-1 AGTLSLGMSQRLGIAAALLGDPPVLLFDEPVNGLDPEGIHWVRTLMRTLA
MAB_4215c|M.abscessus_ATCC_199 AGTFSLGMSQRLGIAVALLGDPKVLLFDEPVNGLDPEGIHWIRTLMQSLA
MAV_3250|M.avium_104 LSTYSGGMYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVSSLR
MUL_3577|M.ulcerans_Agy99 VDTYSGGMRRRLDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLGTLV
Mb2707c|M.bovis_AF2122/97 VGKYSKGMQMRLTFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLK
Rv2688c|M.tuberculosis_H37Rv VGKYSKGMQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLK
MMAR_2026|M.marinum_M AGKYSKGMQMRLTFARALLNDPELLFLDEPTSGMDPVNARSVKNMIMDLK
MLBr_00590|M.leprae_Br4923 YRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLR
* * *: .* :*: * ::::***. *:*. : :: :
MSMEG_0795|M.smegmatis_MC2_155 GEGRTVFVSSHLLAEMANTADRLVVIGQGKLIASTTVTEFVNGSDADTVR
TH_2788|M.thermoresistible__bu AEGRTVLVSSHLLAEMANTADRLLVIGRGRLIASTSVAEFVGSTAAERVR
Mflv_0193|M.gilvum_PYR-GCK AEGRTVLVSSHLLAEMAETADRLVVIGRGRLIASTTVAEFIGGADGAAVR
Mvan_0712|M.vanbaalenii_PYR-1 GEGRTVLVSSHLLSEMANTADRLVVIGRGRLIASTTVTEFIGRSGGAVVR
MAB_4215c|M.abscessus_ATCC_199 AQGRTVLVSSHLLSEMANTADQLVVIGRGRLIAATSMHEFVSRAGADVVR
MAV_3250|M.avium_104 VQGISVLLTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTSYCQ
MUL_3577|M.ulcerans_Agy99 DDGPTLVLTTQYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIV
Mb2707c|M.bovis_AF2122/97 ARGRTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVR
Rv2688c|M.tuberculosis_H37Rv ARGRTIFLTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVR
MMAR_2026|M.marinum_M ARGRTVFLTTHDMATADELCDRVAFVVDGSIVVSDRPAELKIARSQRLVT
MLBr_00590|M.leprae_Br4923 RDGVTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLR
* ::.:::: : .* : .: * ::. *:
MSMEG_0795|M.smegmatis_MC2_155 VRSPQLETLRDVLSDAGLDVVTEP---DGGALNVHG----VAIEVIGDLA
TH_2788|M.thermoresistible__bu VRSPEMDTLRGLLADAGVEVRLEP---DGAALTVRG----AAPEVVGELA
Mflv_0193|M.gilvum_PYR-GCK VRSPRLDDLAAALAAAGMAVVR-----DGAALTVRH----TTTDAVGELA
Mvan_0712|M.vanbaalenii_PYR-1 VRSPRLRDLRTVLAAAGLAVRE-----DGASLTVHD----TTTEAVGELA
MAB_4215c|M.abscessus_ATCC_199 VRSPQIDILRSAAEESGFSVVGGERTGEPGVLEISG----ALIEQVGELA
MAV_3250|M.avium_104 VTPANPAELPQVAAAL-TGLEGIEIDSDTGSVSVFAPDGVATLVEVFRRV
MUL_3577|M.ulcerans_Agy99 VTVSRTEDVANVAAFLRTGVKEVRVDICARRITVAT-HGLLDLSEVARML
Mb2707c|M.bovis_AF2122/97 VEYRG---------------DGGGL--ETAEFGMDGLADDPAFHSVLR--
Rv2688c|M.tuberculosis_H37Rv VEYRG---------------DGGGL--ETAEFGMDGLADDPAFHSVLR--
MMAR_2026|M.marinum_M VEYRG---------------NGGGL--SAAEFSLDTLADDPAFHAVLR--
MLBr_00590|M.leprae_Br4923 FSAPPRLDLSLLAFALPEDYKTTEL--TPGEYLVAGPIDPQVLATVTAWC
. : :
MSMEG_0795|M.smegmatis_MC2_155 ARNAITLHELSRRQASLEEAYLKLT------------------------D
TH_2788|M.thermoresistible__bu ARNGITLHELSVQRASLEDAYLELT------------------------D
Mflv_0193|M.gilvum_PYR-GCK ATHSIPLHELTGQQVSLEQAYLAVT------------------------D
Mvan_0712|M.vanbaalenii_PYR-1 AAHSIALHELSSQQVSLEQAYLAST------------------------D
MAB_4215c|M.abscessus_ATCC_199 ARRGVTLYELSPQRVSLEDAYLSLT------------------------D
MAV_3250|M.avium_104 DALGLELADISLRKPSLDEAFLHLT-------------------------
MUL_3577|M.ulcerans_Agy99 HHYAAPVEDIRLARPSLDDVFVLLTGHHSSSSEGDGRLGAWPALVAGSAE
Mb2707c|M.bovis_AF2122/97 ---NHHVETIHSREASLDDVFVEVTG------------------------
Rv2688c|M.tuberculosis_H37Rv ---NHHVETIHSREASLDDVFVEVTG------------------------
MMAR_2026|M.marinum_M ---EHQVETIHSREASLEDVFVEVTG------------------------
MLBr_00590|M.leprae_Br4923 AQINVLTTNMRVEQHSLEDVFLDLTG------------------------
: . **::.:: *
MSMEG_0795|M.smegmatis_MC2_155 DAVDYRAVQP----------------------------------------
TH_2788|M.thermoresistible__bu AAVEYRAVPR----------------------------------------
Mflv_0193|M.gilvum_PYR-GCK DATEYRGRTR----------------------------------------
Mvan_0712|M.vanbaalenii_PYR-1 DATEYRGTPR----------------------------------------
MAB_4215c|M.abscessus_ATCC_199 DAVQYRSQVNDPLAARATGAVADAEGTH----------------------
MAV_3250|M.avium_104 ----ERTVARS---------------------------------------
MUL_3577|M.ulcerans_Agy99 HARGVRSCARSGRGVLWRSSTLHQLCCGETGNRLARVRWGWRVGLSAGLR
Mb2707c|M.bovis_AF2122/97 -----RQLT-----------------------------------------
Rv2688c|M.tuberculosis_H37Rv -----RQLT-----------------------------------------
MMAR_2026|M.marinum_M -----RRLS-----------------------------------------
MLBr_00590|M.leprae_Br4923 -----RKLR-----------------------------------------
*
MSMEG_0795|M.smegmatis_MC2_155 -----------------------------
TH_2788|M.thermoresistible__bu -----------------------------
Mflv_0193|M.gilvum_PYR-GCK -----------------------------
Mvan_0712|M.vanbaalenii_PYR-1 -----------------------------
MAB_4215c|M.abscessus_ATCC_199 -----------------------------
MAV_3250|M.avium_104 -----------------------------
MUL_3577|M.ulcerans_Agy99 RRTRRGRRAPRNRAASTGLGGLTRVRRRW
Mb2707c|M.bovis_AF2122/97 -----------------------------
Rv2688c|M.tuberculosis_H37Rv -----------------------------
MMAR_2026|M.marinum_M -----------------------------
MLBr_00590|M.leprae_Br4923 -----------------------------