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KVAISGAGVAGAALAHWLHRTGHTRTLIERAPKFRTDGYMIDFWGVGYQAAKRMGIEDPVRAAGYQIERL RSVGSRGEVKADLNVDVFRRMIGEDFTAPRGEDEVRVAAWRFSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0690 | - | - | 100% (115) | oxidoreductase |
| M. ulcerans Agy99 | MUL_2358 | - | 3e-11 | 40.48% (84) | FAD-dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1770 | - | 2e-09 | 33.33% (87) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 6e-44 | 78.85% (104) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 5e-05 | 35.71% (70) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv0575c | - | 6e-44 | 78.85% (104) | hypothetical protein Rv0575c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0649c | - | 8e-12 | 39.74% (78) | putative monooxygenase |
| M. marinum M | MMAR_0939 | - | 9e-53 | 95.19% (104) | oxidoreductase |
| M. avium 104 | MAV_4429 | - | 3e-10 | 34.04% (94) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1980 | - | 3e-27 | 51.92% (104) | hypothetical protein MSMEG_1980 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 1e-05 | 39.06% (64) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0590c|M.bovis_AF2122/97 -------MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMID
Rv0575c|M.tuberculosis_H37Rv -------MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMID
MUL_0690|M.ulcerans_Agy99 -------MKVAISGAGVAGAALAHWLHRTGHTRTLIERAPKFRTDGYMID
MMAR_0939|M.marinum_M -------MKVAISGAGVAGAALAHWLHRTGHTPTLIERAPKFRTGGYMID
MSMEG_1980|M.smegmatis_MC2_155 -------MRIAISGAGIAGPTLAYWLMRAGHEPTLIEAAPRLRTGGYVVD
MAB_0649c|M.abscessus_ATCC_199 -----MSREILISGGGIAGPALAYWLVQEGHSVTIVERAATVRNGGQAVD
Mflv_2621|M.gilvum_PYR-GCK -----MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTGAG-SGIS
Mvan_3960|M.vanbaalenii_PYR-1 -----MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLTSG-AGIS
MAV_4429|M.avium_104 MVGDARPLRVLVVGAGVAGISVARGLLRDGHDVTVFERRPRLAAAGGAVT
. : *.*::* : * * : ** ::.* . :
Mb0590c|M.bovis_AF2122/97 FWGVGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMV
Rv0575c|M.tuberculosis_H37Rv FWGVGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMV
MUL_0690|M.ulcerans_Agy99 FWGVGYQAAKRMGIEDPVRAAGYQIERLRSVGSRGEVKADLNVDVFRRMI
MMAR_0939|M.marinum_M FWGVGYQAAKRMGIEDPVRAAGYQIERLRSVGSRGEVKADLNVDVFRRMI
MSMEG_1980|M.smegmatis_MC2_155 FWGLGYEVACRMGIEPALREQGYDITAIRSVTPDGRIRANLDTAGIRRVT
MAB_0649c|M.abscessus_ATCC_199 FRGPSIDVLDKMGVLDAVRAQATHMGSLVMVDADGKEIARFPSEVIS---
Mflv_2621|M.gilvum_PYR-GCK LWPNALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTWVRRPSVRRIVDAL
Mvan_3960|M.vanbaalenii_PYR-1 IWPNALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTWLRRPSAQRIVHAL
MAV_4429|M.avium_104 VWSNGETVLRQLGVEMDG--AGRQLSSVGAVTSTGRPLATLDVTAMARRL
. . . ::*: . : * :
Mb0590c|M.bovis_AF2122/97 GDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTA
Rv0575c|M.tuberculosis_H37Rv GDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTA
MUL_0690|M.ulcerans_Agy99 GEDFT-APRG----------EDEVR------VAAWRFSS-----------
MMAR_0939|M.marinum_M GEDFTSLPRGDLAAAIYATVEDKVETIFGDSITAIDQHSDGVHLTFEKNA
MSMEG_1980|M.smegmatis_MC2_155 HDKFTSLPRGDLAATIYSTIDGKVETVFGDSIASITEHEDGVAVGLAGGT
MAB_0649c|M.abscessus_ATCC_199 --GELEILWGDLARILHEAVREHVVFRFADSITGVRDDGAKVTVSFSRSA
Mflv_2621|M.gilvum_PYR-GCK GEPLVVVRRSRLTDILREALPAGTVRT-GLAATRVSVGASSVRITLSDGE
Mvan_3960|M.vanbaalenii_PYR-1 GEPLVVVRRSALTEILLDALPPDTVQT-GLSATALSIAAATARVTLSDGR
MAV_4429|M.avium_104 GAPVRMVPRRVLLERLLDGFPTGRIHC-DRRAVALATSRDGVSVEFTDGT
.
Mb0590c|M.bovis_AF2122/97 PRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDER
Rv0575c|M.tuberculosis_H37Rv PRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDER
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0939|M.marinum_M PRDFDLLIGADGLHSNVRRLVFGPEHDYEHYLGCKVAACVVDDYWPRDEL
MSMEG_1980|M.smegmatis_MC2_155 QREFDLVVGADGLHSHVRQLAFGRAPDPEHYLGCLVAAAVVDGYRPRDDL
MAB_0649c|M.abscessus_ATCC_199 PESYDLLIGADGVHSGVRALTFGPEHEFVTQLGQYFTFFAMDNHLGLDHQ
Mflv_2621|M.gilvum_PYR-GCK VRESDAVVGADGVNSVLARTLNGPLR--TRYVG--YTAWRGIAAHPLDPE
Mvan_3960|M.vanbaalenii_PYR-1 TREADAVVGADGVNSMVARALNGPLP--SRYVG--YTAWRGVAAYRLDPA
MAV_4429|M.avium_104 VAEGDVLIGADGLHSMVREWVGARHAKATGWCS--WQGLVSLPEIAESDA
Mb0590c|M.bovis_AF2122/97 SYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKD----ELRDQ
Rv0575c|M.tuberculosis_H37Rv SYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKD----ELRDQ
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0939|M.marinum_M TYVLYNIPGKQVGRVALRGARTMFLFIFRDEHDGADLTPKE----QLRNQ
MSMEG_1980|M.smegmatis_MC2_155 VYMTFSAPGHSVGRVALRGDRTLFLFILRSDDATVPGSHDER-IALLKRE
MAB_0649c|M.abscessus_ATCC_199 TVGFREGTRGVGIQATAPDAPARGSLSFSDDHLEFDYRDVEGNKKLFSER
Mflv_2621|M.gilvum_PYR-GCK LGGETLGPGTQVGHVPLGPDHTYWFATERTAEGGSAPGGEHA---YLTAK
Mvan_3960|M.vanbaalenii_PYR-1 LAGETMSAGTEVGHVPLGPDHTYWFATERTREGSRSAGGEHA---YLTAK
MAV_4429|M.avium_104 ALMMIGGSGNLGLWPAGGAEVQWWFDLPWSTGFVRPQHPIET----IRSH
Mb0590c|M.bovis_AF2122/97 FGDVGWESRDILAALDDVEDLYFDVVSQIR-MDRWSRGRVLLIGDAAGCI
Rv0575c|M.tuberculosis_H37Rv FGDVGWESRDILAALDDVEDLYFDVVSQIR-MDRWSRGRVLLIGDAAGCI
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0939|M.marinum_M FGDAGWECNEILAALDNVDDLYFDVVSQIK-MDRWSRDRVLLIGDAAGCI
MSMEG_1980|M.smegmatis_MC2_155 FSDLGWECERITDALDDVDDLYLDVVSQIR-MDRWSRGRTVLVGDAAACI
MAB_0649c|M.abscessus_ATCC_199 FTGFGWETPAVLRALSVTAEPYFDSLCQVH-LDTYSRGRVCLLGDAAWCA
Mflv_2621|M.gilvum_PYR-GCK VADWADPIPRLVATTDPGDLLRNDLYDRAR-AARWSDGRAVLIGDAAHPM
Mvan_3960|M.vanbaalenii_PYR-1 LAGWADPIPALLASTDPADVLRNDLYDRAQ-PRDWSRGPAVIVGDAAHPM
MAV_4429|M.avium_104 FAGWSEPVDRVLAILTDEDLAASPFPHFRHPIPPPGRGRVTLLGDAAHTM
Mb0590c|M.bovis_AF2122/97 SLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQAS
Rv0575c|M.tuberculosis_H37Rv SLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQAS
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0939|M.marinum_M SLLGGEGTGLAMTEAYVLAGELERAGGDHRRAFDAYEAQLRPFIADKQAG
MSMEG_1980|M.smegmatis_MC2_155 SLLGGEGTGLAMAEAYVLAGELAAHR-DHRDAFSAYETALRPLIAAKQEA
MAB_0649c|M.abscessus_ATCC_199 SPRSGMGTSLAIVGAYVLAHELRSAQGDFSIAFARFHTLMAPYAARCQRL
Mflv_2621|M.gilvum_PYR-GCK RPHLGQGGCQGIEDAAILA-RFLELADDVPTAFERFEAFRKPRVGMLVRE
Mvan_3960|M.vanbaalenii_PYR-1 RPHLGQGGCQGLEDAAILA-RFVGLSPDLPAAFDRFGAFRRRRVRPLVRE
MAV_4429|M.avium_104 PPTLAQGTNQALLDTMVLCQALADFGRGTPGGQADVANALRWYEKTRRRR
Mb0590c|M.bovis_AF2122/97 AAKFIWFFRHPN----PIRPVVSQR---CDAHDELR-PAGDAVRR--QRA
Rv0575c|M.tuberculosis_H37Rv AAKFIWFFATRTRFGLWFRNVAMRT---MNFGPLAT-LFAGSVRD--DFE
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0939|M.marinum_M AARFIGFFATRTRFGLWFRNIAMRT---MNIGPLAT-LFAGSVRD--DFE
MSMEG_1980|M.smegmatis_MC2_155 ARRYLAVFIPKTNLGIAFRDLCMRV---VNAVPWTDRLLARTFSD--DFA
MAB_0649c|M.abscessus_ATCC_199 ALDALKIGEADSPWATGLRRLGLWS---LRLPGIRQLVARQALKVGRSFA
Mflv_2621|M.gilvum_PYR-GCK AQTLGRIVNVRPAVLSGLAGRATAL---IPERMVTAHLAWIAAGS--AFV
Mvan_3960|M.vanbaalenii_PYR-1 SAAIGRIVNLRPAFLSGVASRASAL---IPEWAVASHLASIAAGS--AFI
MAV_4429|M.avium_104 VRAVSWVASLPVSHGEAVLRPAALVSDRLQAAALTMFLRWTSHRRMSDHI
Mb0590c|M.bovis_AF2122/97 ----------------------
Rv0575c|M.tuberculosis_H37Rv LPDYTW----------------
MUL_0690|M.ulcerans_Agy99 ----------------------
MMAR_0939|M.marinum_M LPDYDLA---------------
MSMEG_1980|M.smegmatis_MC2_155 LPEYRL----------------
MAB_0649c|M.abscessus_ATCC_199 LPAYD-----------------
Mflv_2621|M.gilvum_PYR-GCK LPTAADLAR-------------
Mvan_3960|M.vanbaalenii_PYR-1 LPTAGDVGG-------------
MAV_4429|M.avium_104 NRSVGEAINRSLGEAPKIPSRR