For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMIDFWGVGYQVAKRMGITDQIAAAGYHMEHV RSVGPTGKVKADLGVDVFRRMVGDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFER TAPRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDERSYVLYNTVDRQLARFALR GDRTMFLFVFRAEHDNPGVAPKDELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLI GDAAGCISLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFATRTR FGLWFRNVAMRTMNFGPLATLFAGSVRDDFELPDYTW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0575c | - | - | 100% (388) | hypothetical protein Rv0575c |
| M. tuberculosis H37Rv | Rv1260 | - | 1e-59 | 40.63% (347) | hypothetical protein Rv1260 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 0.0 | 100.00% (346) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 2e-12 | 26.98% (341) | monooxygenase, FAD-binding |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 8e-61 | 37.22% (403) | hypothetical protein MAB_2678 |
| M. marinum M | MMAR_0939 | - | 0.0 | 81.35% (386) | oxidoreductase |
| M. avium 104 | MAV_1408 | - | 1e-55 | 39.37% (348) | hypothetical protein MAV_1408 |
| M. smegmatis MC2 155 | MSMEG_1980 | - | 1e-122 | 56.78% (391) | hypothetical protein MSMEG_1980 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4482 | - | 1e-53 | 39.08% (348) | hypothetical protein MUL_4482 |
| M. vanbaalenii PYR-1 | Mvan_5278 | - | 4e-12 | 24.63% (337) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0575c|M.tuberculosis_H37Rv ----MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFW
Mb0590c|M.bovis_AF2122/97 ----MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFW
MMAR_0939|M.marinum_M ----MKVAISGAGVAGAALAHWLHRTGHTPTLIERAPKFR-TGGYMIDFW
MSMEG_1980|M.smegmatis_MC2_155 ----MRIAISGAGIAGPTLAYWLMRAGHEPTLIEAAPRLR-TGGYVVDFW
MAV_1408|M.avium_104 ---MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPR-PGGQAIDVR
MUL_4482|M.ulcerans_Agy99 MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLR-PGGQAIDVR
MAB_2678|M.abscessus_ATCC_1997 ----MRVLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHAVDLF
Mflv_2621|M.gilvum_PYR-GCK --MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG--AGSGISLW
Mvan_5278|M.vanbaalenii_PYR-1 ----MKVVIVGAGMGGMSAAIALRQIGIDTVVYERVTENK-PVGAAISVW
: : **.:.* * * : * : * * :..
Rv0575c|M.tuberculosis_H37Rv GVGYQVAKRMGITDQIAAAGYHMEHVRSVG-PTGKVKADLGVD----VFR
Mb0590c|M.bovis_AF2122/97 GVGYQVAKRMGITDQIAAAGYHMEHVRSVG-PTGKVKADLGVD----VFR
MMAR_0939|M.marinum_M GVGYQAAKRMGIEDPVRAAGYQIERLRSVG-SRGEVKADLNVD----VFR
MSMEG_1980|M.smegmatis_MC2_155 GLGYEVACRMGIEPALREQGYDITAIRSVT-PDGRIRANLDTA----GIR
MAV_1408|M.avium_104 GPALGVLERMGLLAAAAKRRTQIRGSSVVD-RDGNELSRDTEAAISGPTG
MUL_4482|M.ulcerans_Agy99 GPALTVLDRMGILDAARDRKTGIRGASVVD-RDGNELSRDTES---TPTG
MAB_2678|M.abscessus_ATCC_1997 KPAMDIIEMMGILDHVEAQSAGTEVLSIH--REGKRLIDLPEV----LIF
Mflv_2621|M.gilvum_PYR-GCK PNALAALDQIGLGDSVRDAGGRVTAGAIRW-RDGTWVRRPSVR----RIV
Mvan_5278|M.vanbaalenii_PYR-1 SNGVKCLNYLGLQEETAELGGKVETMSYVDGHTGDTMCRFSMH----PLI
. :*: *
Rv0575c|M.tuberculosis_H37Rv RMVGDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATID--EHRDGVRLT
Mb0590c|M.bovis_AF2122/97 RMVGDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATID--EHRDGVRLT
MMAR_0939|M.marinum_M RMIGEDFTSLPRGDLAAAIYATVEDKVETIFGDSITAID--QHSDGVHLT
MSMEG_1980|M.smegmatis_MC2_155 RVTHDKFTSLPRGDLAATIYSTIDGKVETVFGDSIASIT--EHEDGVAVG
MAV_1408|M.avium_104 GPIEGPDIELLRDDLVELLYGASQWTAEYLFDDTITALD--DRGAAVRVS
MUL_4482|M.ulcerans_Agy99 GPIDSPNIELLRDDLIELLDGTIQSTTEFIFDDSIATLQ--DDGAAVEVT
MAB_2678|M.abscessus_ATCC_1997 SAVSERHVEIMRDDLSEILYGASAPSAEYIFGDSITALT--DDGAGVRVA
Mflv_2621|M.gilvum_PYR-GCK DALGEPLVVVRRSRLTDILREALP-AGTVRTGLAATRVS--VGASSVRIT
Mvan_5278|M.vanbaalenii_PYR-1 EQVGQRPYPIARAELQLMLMKAYG-IDDINFGMKMVGVENDTAGSAAKAT
: * * : : . . : ..
Rv0575c|M.tuberculosis_H37Rv FERTAPRDFDLVIGADGLHSNVRRLVFG--PERDFEHYLGCKVAACVVDG
Mb0590c|M.bovis_AF2122/97 FERTAPRDFDLVIGADGLHSNVRRLVFG--PERDFEHYLGCKVAACVVDG
MMAR_0939|M.marinum_M FEKNAPRDFDLLIGADGLHSNVRRLVFG--PEHDYEHYLGCKVAACVVDD
MSMEG_1980|M.smegmatis_MC2_155 LAGGTQREFDLVVGADGLHSHVRQLAFG--RAPDPEHYLGCLVAAAVVDG
MAV_1408|M.avium_104 FERAAPRDFDLVIGADGLHSNVRRLVFG--PEDEFIERLGTHAAIFTVPN
MUL_4482|M.ulcerans_Agy99 FVRSGTRTFDFLIGADGLHSNVRRKVFG--PEEQFIKRLGTYAAIFTVPN
MAB_2678|M.abscessus_ATCC_1997 FDRASDRRFDLVIGADGLHSHVRGLVFG--PESGYSHWLGQYLAVASIPN
Mflv_2621|M.gilvum_PYR-GCK LSDGEVRESDAVVGADGVNSVLARTLNG--PLR--TRYVGYTAWRGIAAH
Mvan_5278|M.vanbaalenii_PYR-1 FADGTTVSADVIIGADGAGSITREYVLGGPVSRRYAGYVNYNGLVSTDDA
: * ::**** * * :.
Rv0575c|M.tuberculosis_H37Rv YRPRDERSYVLYNTVDRQ--LARFALRGDRTMFLFVFRAEHDNPGVAPKD
Mb0590c|M.bovis_AF2122/97 YRPRDERSYVLYNTVDRQ--LARFALRGDRTMFLFVFRAEHDNPGVAPKD
MMAR_0939|M.marinum_M YWPRDELTYVLYNIPGKQ--VGRVALRGARTMFLFIFRDEHDGADLTPKE
MSMEG_1980|M.smegmatis_MC2_155 YRPRDDLVYMTFSAPGHS--VGRVALRGDRTLFLFILRSDDATVPGSHDE
MAV_1408|M.avium_104 FLGLDYWQMWHYGDSTMAGVYSARDNAEARAMLGFMDAE-LRLDYRDTEA
MUL_4482|M.ulcerans_Agy99 FLELDYWQKWHYGDNTMAGVYSARDNSEARAALGFMDTE-LQIDYRDTEA
MAB_2678|M.abscessus_ATCC_1997 YLDLSDRALMYPQVDKIAGMYSAAQLSDARAFFLFRTPEPLDYHHRDVGR
Mflv_2621|M.gilvum_PYR-GCK PLDPELGGETLGPGTQVG----HVPLGPDHTYWFATERTAEGGS--APGG
Mvan_5278|M.vanbaalenii_PYR-1 IGPATEWTTYVGDGKRVS----VMPVSDDRFYFFFDVVEPQGSPYEEGRV
:
Rv0575c|M.tuberculosis_H37Rv ---ELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLI
Mb0590c|M.bovis_AF2122/97 ---ELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLI
MMAR_0939|M.marinum_M ---QLRNQFGDAGWECNEILAALDNVDDLYFDVVSQIKMDRWSRDRVLLI
MSMEG_1980|M.smegmatis_MC2_155 RIALLKREFSDLGWECERITDALDDVDDLYLDVVSQIRMDRWSRGRTVLV
MAV_1408|M.avium_104 QFAELERRMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSRGRVALV
MUL_4482|M.ulcerans_Agy99 QFAELERRMIEDGWVRAQLLHYMRSAPDFYFDEMAQIVMDSWAKGRVALV
MAB_2678|M.abscessus_ATCC_1997 QKALLGEVYADVGWELPRMLAEVDATDTFYMDSITQLRMDTWSKGRITLV
Mflv_2621|M.gilvum_PYR-GCK EHAYLTAKVADWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAVLI
Mvan_5278|M.vanbaalenii_PYR-1 R-EVLRAHFAGWTPGVQTLIDTLDPLATNRVEILDLDPFHTWVKGRVAVL
* : : * .* ::
Rv0575c|M.tuberculosis_H37Rv GDAAGCISLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPF
Mb0590c|M.bovis_AF2122/97 GDAAGCISLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPF
MMAR_0939|M.marinum_M GDAAGCISLLGGEGTGLAMTEAYVLAGELERAGGDHRRAFDAYEAQLRPF
MSMEG_1980|M.smegmatis_MC2_155 GDAAACISLLGGEGTGLAMAEAYVLAGELA-AHRDHRDAFSAYETALRPL
MAV_1408|M.avium_104 GDAGYCCSPLSGQGTSVALLGAYILAGELKAAGEDHEAGFANYHREFADY
MUL_4482|M.ulcerans_Agy99 GDAAYCCSPLSGQGTSVAVLGAYILAGELAAAGNDYQRGFANYHAEFSGF
MAB_2678|M.abscessus_ATCC_1997 GDAGYCPGPAVGGSTSLAVVGAYVLAGEIAAAAGDHARAYPAYEAALREY
Mflv_2621|M.gilvum_PYR-GCK GDAAHPMRPHLGQGGCQGIEDAAILA-RFLELADDVPTAFERFEAFRKPR
Mvan_5278|M.vanbaalenii_PYR-1 GDAAHNTTPDIGQGGCSAMEDAIALQWAFKDHPDDVHAALAAYQSARTER
***. * . .: * * : * . :.
Rv0575c|M.tuberculosis_H37Rv IEGKQASAAKFIWFFATRTRFGLWFRNVAMRTMNFGPLAT-LFAGSVRDD
Mb0590c|M.bovis_AF2122/97 IEGKQASAAKFIWFFRHPN----PIRPVVSQRCDAHDELR-PAGDAVRRQ
MMAR_0939|M.marinum_M IADKQAGAARFIGFFATRTRFGLWFRNIAMRTMNIGPLAT-LFAGSVRDD
MSMEG_1980|M.smegmatis_MC2_155 IAAKQEAARRYLAVFIPKTNLGIAFRDLCMRVVNAVPWTDRLLARTFSDD
MAV_1408|M.avium_104 VQRNQWLVVDN----IPG----------GAPIP-------QEVFERIVAS
MUL_4482|M.ulcerans_Agy99 GERNQWLVTDN----IPG----------GEPIP-------EEAFERIVNS
MAB_2678|M.abscessus_ATCC_1997 VEVSRKLALTASGTLVPKSRLGLCTLVHGARILGHLPSSLTRSLSRLVAA
Mflv_2621|M.gilvum_PYR-GCK VGMLVREAQTLGRIVNVRPAVLSGLAGRATALIPERMVTAHLAWIAAGSA
Mvan_5278|M.vanbaalenii_PYR-1 AADLVLRARKRCDVTHAKDPQVTSRWYDELRNEDGTNIIRGIVGNIVGGP
.
Rv0575c|M.tuberculosis_H37Rv --------FELPDYTW----
Mb0590c|M.bovis_AF2122/97 --------RA----------
MMAR_0939|M.marinum_M --------FELPDYDLA---
MSMEG_1980|M.smegmatis_MC2_155 --------FALPEYRL----
MAV_1408|M.avium_104 --------ITLKDY------
MUL_4482|M.ulcerans_Agy99 --------LELEDYRQG---
MAB_2678|M.abscessus_ATCC_1997 RRINIHDTFALRDYQGLISR
Mflv_2621|M.gilvum_PYR-GCK --------FVLPTAADLAR-
Mvan_5278|M.vanbaalenii_PYR-1 --------LTPVTAATEG--