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RIAISGAGIAGPTLAYWLMRAGHEPTLIEAAPRLRTGGYVVDFWGLGYEVACRMGIEPALREQGYDITAI RSVTPDGRIRANLDTAGIRRVTHDKFTSLPRGDLAATIYSTIDGKVETVFGDSIASITEHEDGVAVGLAG GTQREFDLVVGADGLHSHVRQLAFGRAPDPEHYLGCLVAAAVVDGYRPRDDLVYMTFSAPGHSVGRVALR GDRTLFLFILRSDDATVPGSHDERIALLKREFSDLGWECERITDALDDVDDLYLDVVSQIRMDRWSRGRT VLVGDAAACISLLGGEGTGLAMAEAYVLAGELAAHRDHRDAFSAYETALRPLIAAKQEAARRYLAVFIPK TNLGIAFRDLCMRVVNAVPWTDRLLARTFSDDFALPEYRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1980 | - | - | 100% (391) | hypothetical protein MSMEG_1980 |
| M. smegmatis MC2 155 | MSMEG_3318 | - | 4e-57 | 37.12% (396) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3039 | - | 7e-46 | 33.33% (405) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 1e-115 | 58.86% (350) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 6e-20 | 29.15% (343) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv0575c | - | 1e-123 | 56.78% (391) | hypothetical protein Rv0575c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 1e-57 | 35.89% (404) | hypothetical protein MAB_2678 |
| M. marinum M | MMAR_0939 | - | 1e-125 | 57.40% (392) | oxidoreductase |
| M. avium 104 | MAV_0984 | - | 2e-48 | 34.31% (411) | hypothetical protein MAV_0984 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1770 | - | 6e-50 | 35.45% (409) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 3e-17 | 28.57% (364) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0590c|M.bovis_AF2122/97 ---MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWG
Rv0575c|M.tuberculosis_H37Rv ---MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWG
MMAR_0939|M.marinum_M ---MKVAISGAGVAGAALAHWLHRTGHTPTLIERAPKFR-TGGYMIDFWG
MSMEG_1980|M.smegmatis_MC2_155 ---MRIAISGAGIAGPTLAYWLMRAGHEPTLIEAAPRLR-TGGYVVDFWG
MAB_2678|M.abscessus_ATCC_1997 ---MRVLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHAVDLFK
MAV_0984|M.avium_104 ---MRILISGASIAGPVLAYWLTRYGFEVTVVERAPTLRKTGGHAVDLFR
MUL_1770|M.ulcerans_Agy99 MAKPIVLISGAGIAGPALAFWLTHSGYQVVVTELADDIR-PGGQTVDLRG
Mflv_2621|M.gilvum_PYR-GCK -MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG--AGSGISLWP
Mvan_3960|M.vanbaalenii_PYR-1 -MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLT--SGAGISIWP
: **.::* . * * : *. : * .* :.:
Mb0590c|M.bovis_AF2122/97 VGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMVGDD
Rv0575c|M.tuberculosis_H37Rv VGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMVGDD
MMAR_0939|M.marinum_M VGYQAAKRMGIEDPVRAAGYQIERLRSVGSRGEVKADLNVDVFRRMIGED
MSMEG_1980|M.smegmatis_MC2_155 LGYEVACRMGIEPALREQGYDITAIRSVTPDGRIRANLDTAGIRRVTHDK
MAB_2678|M.abscessus_ATCC_1997 PAMDIIEMMGILDHVEAQSAGTEVLSIHREGK-RLIDLPEVLIFSAVSER
MAV_0984|M.avium_104 PAMEISAKMGVLPRIEDLATGTTRLTLYREGRPQPSRIDLTKIYAASSDR
MUL_1770|M.ulcerans_Agy99 AGRLVIERMGLLEQMRQRSLRQRGIAWIRADGRRRAEMPVEAFHGNGPVS
Mflv_2621|M.gilvum_PYR-GCK NALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTWVRRPSVRRIVDALGEP
Mvan_3960|M.vanbaalenii_PYR-1 NALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTWLRRPSAQRIVHALGEP
. :*: : . :
Mb0590c|M.bovis_AF2122/97 FTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTAPRD
Rv0575c|M.tuberculosis_H37Rv FTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTAPRD
MMAR_0939|M.marinum_M FTSLPRGDLAAAIYATVEDKVETIFGDSITAIDQHSDGVHLTFEKNAPRD
MSMEG_1980|M.smegmatis_MC2_155 FTSLPRGDLAATIYSTIDGKVETVFGDSIASITEHEDGVAVGLAGGTQRE
MAB_2678|M.abscessus_ATCC_1997 HVEIMRDDLSEILYGASAPSAEYIFGDSITALTDDGAGVRVAFDRASDRR
MAV_0984|M.avium_104 HVEIMRDDLSEVYYDAARDDVEYLFGDSITAIEPDGT---VTFEHCAPRT
MUL_1770|M.ulcerans_Agy99 ELEILRGDLAAVLYRATAAGTDYRFGTRITDLAPSGDAVQARLSDGTTVR
Mflv_2621|M.gilvum_PYR-GCK LVVVRRSRLTDILREALPAGTVRT-GLAATRVSVGASSVRITLSDGEVRE
Mvan_3960|M.vanbaalenii_PYR-1 LVVVRRSALTEILLDALPPDTVQT-GLSATALSIAAATARVTLSDGRTRE
: *. *: : . . : : :
Mb0590c|M.bovis_AF2122/97 FDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDE--RS
Rv0575c|M.tuberculosis_H37Rv FDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDE--RS
MMAR_0939|M.marinum_M FDLLIGADGLHSNVRRLVFGPEHDYEHYLGCKVAACVVDDYWPRDE--LT
MSMEG_1980|M.smegmatis_MC2_155 FDLVVGADGLHSHVRQLAFGRAPDPEHYLGCLVAAAVVDGYRPRDD--LV
MAB_2678|M.abscessus_ATCC_1997 FDLVIGADGLHSHVRGLVFGPESGYSHWLGQYLAVASIPNYLDLSDRALM
MAV_0984|M.avium_104 FDVVVGADGLHSNVRRLTFGDEAGLTRFLGGYLSVVSAPKTLVGPGEMVG
MUL_1770|M.ulcerans_Agy99 ADLVVGADGPHSGVRRLAFGPEEQFARPLGGYNAWFSAPDTVGLNGWYLM
Mflv_2621|M.gilvum_PYR-GCK SDAVVGADGVNSVLARTLNGPLRTRYVGYTAWRGIAAHPLDPELGG----
Mvan_3960|M.vanbaalenii_PYR-1 ADAVVGADGVNSMVARALNGPLPSRYVGYTAWRGVAAYRLDPALAG----
* ::**** :* : * .
Mb0590c|M.bovis_AF2122/97 YVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKD---ELRDQFG
Rv0575c|M.tuberculosis_H37Rv YVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKD---ELRDQFG
MMAR_0939|M.marinum_M YVLYNIPGKQVGRVALRGARTMFLFIFRDEHDGADLTPKE---QLRNQFG
MSMEG_1980|M.smegmatis_MC2_155 YMTFSAPGHSVGRVALRGDRTLFLFILRSDDATVPGSHDERIALLKREFS
MAB_2678|M.abscessus_ATCC_1997 YPQVDKIAGMYSAAQLSDARAFFLFRTPEPLDYHHRDVGRQKALLGEVYA
MAV_0984|M.avium_104 HVGVGRFAGIYTADHLDDARAVFLFRSAAELAYDHRDTARQKELLREAFA
MUL_1770|M.ulcerans_Agy99 YQAPGGLNASMRPSHDPATAKAGLAFRSAPIRYDRGDLDAQRDLLAACFA
Mflv_2621|M.gilvum_PYR-GCK --ETLGPGTQVGHVPLGPDHTYWFATERTAEG--GSAPGGEHAYLTAKVA
Mvan_3960|M.vanbaalenii_PYR-1 --ETMSAGTEVGHVPLGPDHTYWFATERTREG--SRSAGGEHAYLTAKLA
: * .
Mb0590c|M.bovis_AF2122/97 DVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLL
Rv0575c|M.tuberculosis_H37Rv DVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLL
MMAR_0939|M.marinum_M DAGWECNEILAALDNVDDLYFDVVSQIKMDRWSRDRVLLIGDAAGCISLL
MSMEG_1980|M.smegmatis_MC2_155 DLGWECERITDALDDVDDLYLDVVSQIRMDRWSRGRTVLVGDAAACISLL
MAB_2678|M.abscessus_ATCC_1997 DVGWELPRMLAEVDATDTFYMDSITQLRMDTWSKGRITLVGDAGYCPGPA
MAV_0984|M.avium_104 GMHDEVDGWLAETERTPTFYFDSITQLRTDRWSRRRVTLVGDAGYCPGPA
MUL_1770|M.ulcerans_Agy99 GAGWQSDALIAAAREADDFYLDAIVQIHLDAWSRGRVTLVGDAGYCASPL
Mflv_2621|M.gilvum_PYR-GCK DWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAVLIGDAAHPMRPH
Mvan_3960|M.vanbaalenii_PYR-1 GWADPIPALLASTDPADVLRNDLYDRAQPRDWSRGPAVIVGDAAHPMRPH
. : * : : ** ::***.
Mb0590c|M.bovis_AF2122/97 GGEGTGLAITEAYVLAGELARAGGDHR------RAFDAYEKRLRPFIEGK
Rv0575c|M.tuberculosis_H37Rv GGEGTGLAITEAYVLAGELARAGGDHR------RAFDAYEKRLRPFIEGK
MMAR_0939|M.marinum_M GGEGTGLAMTEAYVLAGELERAGGDHR------RAFDAYEAQLRPFIADK
MSMEG_1980|M.smegmatis_MC2_155 GGEGTGLAMAEAYVLAGELA-AHRDHR------DAFSAYETALRPLIAAK
MAB_2678|M.abscessus_ATCC_1997 VGGSTSLAVVGAYVLAGEIAAAAGDHA------RAYPAYEAALREYVEVS
MAV_0984|M.avium_104 VGGSTSLAVLGAYVLAGELARADGDHL------RAFAAYELQMRESVRRS
MUL_1770|M.ulcerans_Agy99 SGMGTSLALVGAYVLAGELGPAHGDGIDEAALAAALARYETVLRPYVANC
Mflv_2621|M.gilvum_PYR-GCK LGQGGCQGIEDAAILARFLELADDVPT-------AFERFEAFRKPRVGML
Mvan_3960|M.vanbaalenii_PYR-1 LGQGGCQGLEDAAILARFVGLSPDLPA-------AFDRFGAFRRRRVRPL
* . .: * :** : : * : : :
Mb0590c|M.bovis_AF2122/97 QASAAKFIWFFRHPN----PIRPVVSQRCDAHDELR---------PAGDA
Rv0575c|M.tuberculosis_H37Rv QASAAKFIWFFATRTRFGLWFRNVAMRTMNFGPLAT---------LFAGS
MMAR_0939|M.marinum_M QAGAARFIGFFATRTRFGLWFRNIAMRTMNIGPLAT---------LFAGS
MSMEG_1980|M.smegmatis_MC2_155 QEAARRYLAVFIPKTNLGIAFRDLCMRVVNAVPWTDR--------LLART
MAB_2678|M.abscessus_ATCC_1997 RKLALTASGTLVPKSRLGLCTLVHGARILGHLPSSLTRSLSRLVAARRIN
MAV_0984|M.avium_104 RSFARAAARGVIPGSRAGVWALTRGAQLVSAMPTSLARALAKLNTKG-VR
MUL_1770|M.ulcerans_Agy99 QDLPN-SIDRFLPMSESEIRSNAAAMKYMQRWPFRFFAER------KWFT
Mflv_2621|M.gilvum_PYR-GCK VREAQTLGRIVNVRPAVLSGLAGRATALIPERMVTAH--------LAWIA
Mvan_3960|M.vanbaalenii_PYR-1 VRESAAIGRIVNLRPAFLSGVASRASALIPEWAVASH--------LASIA
. .
Mb0590c|M.bovis_AF2122/97 VRRQRA----------
Rv0575c|M.tuberculosis_H37Rv VRDDFELPDYTW----
MMAR_0939|M.marinum_M VRDDFELPDYDLA---
MSMEG_1980|M.smegmatis_MC2_155 FSDDFALPEYRL----
MAB_2678|M.abscessus_ATCC_1997 IHDTFALRDYQGLISR
MAV_0984|M.avium_104 MHDSMPVPDYAGSDV-
MUL_1770|M.ulcerans_Agy99 IAESIELPRYPRLP--
Mflv_2621|M.gilvum_PYR-GCK AGSAFVLPTAADLAR-
Mvan_3960|M.vanbaalenii_PYR-1 AGSAFILPTAGDVGG-