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KVAISGAGVAGAALAHWLHRTGHTPTLIERAPKFRTGGYMIDFWGVGYQAAKRMGIEDPVRAAGYQIERL RSVGSRGEVKADLNVDVFRRMIGEDFTSLPRGDLAAAIYATVEDKVETIFGDSITAIDQHSDGVHLTFEK NAPRDFDLLIGADGLHSNVRRLVFGPEHDYEHYLGCKVAACVVDDYWPRDELTYVLYNIPGKQVGRVALR GARTMFLFIFRDEHDGADLTPKEQLRNQFGDAGWECNEILAALDNVDDLYFDVVSQIKMDRWSRDRVLLI GDAAGCISLLGGEGTGLAMTEAYVLAGELERAGGDHRRAFDAYEAQLRPFIADKQAGAARFIGFFATRTR FGLWFRNIAMRTMNIGPLATLFAGSVRDDFELPDYDLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0939 | - | - | 100% (389) | oxidoreductase |
| M. marinum M | MMAR_4180 | - | 3e-53 | 37.68% (345) | oxidoreductase |
| M. marinum M | MMAR_4675 | - | 3e-51 | 35.36% (362) | membrane-associated oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 1e-163 | 79.77% (346) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 2e-16 | 28.44% (334) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv0575c | - | 0.0 | 81.35% (386) | hypothetical protein Rv0575c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 2e-58 | 36.66% (401) | hypothetical protein MAB_2678 |
| M. avium 104 | MAV_1408 | - | 3e-53 | 37.64% (348) | hypothetical protein MAV_1408 |
| M. smegmatis MC2 155 | MSMEG_1980 | - | 1e-125 | 57.40% (392) | hypothetical protein MSMEG_1980 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0690 | - | 4e-52 | 95.19% (104) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 2e-16 | 27.49% (342) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0939|M.marinum_M --MKVAISGAGVAGAALAHWLHRTGHTPTLIERAPKFR-TGGYMIDFWGV
MUL_0690|M.ulcerans_Agy99 --MKVAISGAGVAGAALAHWLHRTGHTRTLIERAPKFR-TDGYMIDFWGV
Mb0590c|M.bovis_AF2122/97 --MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWGV
Rv0575c|M.tuberculosis_H37Rv --MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWGV
MSMEG_1980|M.smegmatis_MC2_155 --MRIAISGAGIAGPTLAYWLMRAGHEPTLIEAAPRLR-TGGYVVDFWGL
MAB_2678|M.abscessus_ATCC_1997 --MRVLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHAVDLFKP
MAV_1408|M.avium_104 -MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPR-PGGQAIDVRGP
Mflv_2621|M.gilvum_PYR-GCK MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG--AGSGISLWPN
Mvan_3960|M.vanbaalenii_PYR-1 MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLT--SGAGISIWPN
: **.::* . * * : *. :::* * :..
MMAR_0939|M.marinum_M GYQAAKRMGIEDPVRAAGYQIERLRSVGSRGEVKADLNVDVFRR----MI
MUL_0690|M.ulcerans_Agy99 GYQAAKRMGIEDPVRAAGYQIERLRSVGSRGEVKADLNVDVFRR----MI
Mb0590c|M.bovis_AF2122/97 GYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRR----MV
Rv0575c|M.tuberculosis_H37Rv GYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRR----MV
MSMEG_1980|M.smegmatis_MC2_155 GYEVACRMGIEPALREQGYDITAIRSVTPDGRIRANLDTAGIRR----VT
MAB_2678|M.abscessus_ATCC_1997 AMDIIEMMGILDHVEAQSAGTEVLSIH-REGKRLIDLPEVLIFS----AV
MAV_1408|M.avium_104 ALGVLERMGLLAAAAKRRTQIRGSSVVDRDGNELSRDTEAAISGPTGGPI
Mflv_2621|M.gilvum_PYR-GCK ALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTWVRRPSVRRIVD----AL
Mvan_3960|M.vanbaalenii_PYR-1 ALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTWLRRPSAQRIVH----AL
. :*: * :
MMAR_0939|M.marinum_M GEDFTSLPRGDLAAAIYATVEDKVETIFGDSITAIDQHSDGVHLTFEKNA
MUL_0690|M.ulcerans_Agy99 GEDFT-APRG----------EDEVR------VAAWRFSS-----------
Mb0590c|M.bovis_AF2122/97 GDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTA
Rv0575c|M.tuberculosis_H37Rv GDDFTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTA
MSMEG_1980|M.smegmatis_MC2_155 HDKFTSLPRGDLAATIYSTIDGKVETVFGDSIASITEHEDGVAVGLAGGT
MAB_2678|M.abscessus_ATCC_1997 SERHVEIMRDDLSEILYGASAPSAEYIFGDSITALTDDGAGVRVAFDRAS
MAV_1408|M.avium_104 EGPDIELLRDDLVELLYGASQWTAEYLFDDTITALDDRGAAVRVSFERAA
Mflv_2621|M.gilvum_PYR-GCK GEPLVVVRRSRLTDILREALPAGTVRT-GLAATRVSVGASSVRITLSDGE
Mvan_3960|M.vanbaalenii_PYR-1 GEPLVVVRRSALTEILLDALPPDTVQT-GLSATALSIAAATARVTLSDGR
*. . :
MMAR_0939|M.marinum_M PRDFDLLIGADGLHSNVRRLVFGPEHDYEHYLGCKVAACVVDDYWPRDEL
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 PRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDER
Rv0575c|M.tuberculosis_H37Rv PRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDER
MSMEG_1980|M.smegmatis_MC2_155 QREFDLVVGADGLHSHVRQLAFGRAPDPEHYLGCLVAAAVVDGYRPRDDL
MAB_2678|M.abscessus_ATCC_1997 DRRFDLVIGADGLHSHVRGLVFGPESGYSHWLGQYLAVASIPNYLDLSDR
MAV_1408|M.avium_104 PRDFDLVIGADGLHSNVRRLVFGPEDEFIERLGTHAAIFTVPNFLGLDYW
Mflv_2621|M.gilvum_PYR-GCK VRESDAVVGADGVNSVLARTLNGPLR--TRYVGYTAWRGIAAHPLDPELG
Mvan_3960|M.vanbaalenii_PYR-1 TREADAVVGADGVNSMVARALNGPLP--SRYVGYTAWRGVAAYRLDPALA
MMAR_0939|M.marinum_M TYVLYNIPGKQ--VGRVALRGARTMFLFIFRDEHDGADLTPKE---QLRN
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 SYVLYNTVDRQ--LARFALRGDRTMFLFVFRAEHDNPGVAPKD---ELRD
Rv0575c|M.tuberculosis_H37Rv SYVLYNTVDRQ--LARFALRGDRTMFLFVFRAEHDNPGVAPKD---ELRD
MSMEG_1980|M.smegmatis_MC2_155 VYMTFSAPGHS--VGRVALRGDRTLFLFILRSDDATVPGSHDERIALLKR
MAB_2678|M.abscessus_ATCC_1997 ALMYPQVDKIAGMYSAAQLSDARAFFLFRTPEPLDYHHRDVGRQKALLGE
MAV_1408|M.avium_104 QMWHYGDSTMAGVYSARDNAEARAMLGFMDAE-LRLDYRDTEAQFAELER
Mflv_2621|M.gilvum_PYR-GCK GETLGPGTQVG----HVPLGPDHTYWFATERTAEGGS--APGGEHAYLTA
Mvan_3960|M.vanbaalenii_PYR-1 GETMSAGTEVG----HVPLGPDHTYWFATERTREGSR--SAGGEHAYLTA
MMAR_0939|M.marinum_M QFGDAGWECNEILAALDNVDDLYFDVVSQIKMDRWSRDRVLLIGDAAGCI
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 QFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCI
Rv0575c|M.tuberculosis_H37Rv QFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCI
MSMEG_1980|M.smegmatis_MC2_155 EFSDLGWECERITDALDDVDDLYLDVVSQIRMDRWSRGRTVLVGDAAACI
MAB_2678|M.abscessus_ATCC_1997 VYADVGWELPRMLAEVDATDTFYMDSITQLRMDTWSKGRITLVGDAGYCP
MAV_1408|M.avium_104 RMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSRGRVALVGDAGYCC
Mflv_2621|M.gilvum_PYR-GCK KVADWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAVLIGDAAHPM
Mvan_3960|M.vanbaalenii_PYR-1 KLAGWADPIPALLASTDPADVLRNDLYDRAQPRDWSRGPAVIVGDAAHPM
MMAR_0939|M.marinum_M SLLGGEGTGLAMTEAYVLAGELERAGGDHRRAFDAYEAQLRPFIADKQAG
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 SLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQAS
Rv0575c|M.tuberculosis_H37Rv SLLGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQAS
MSMEG_1980|M.smegmatis_MC2_155 SLLGGEGTGLAMAEAYVLAGELAAHR-DHRDAFSAYETALRPLIAAKQEA
MAB_2678|M.abscessus_ATCC_1997 GPAVGGSTSLAVVGAYVLAGEIAAAAGDHARAYPAYEAALREYVEVSRKL
MAV_1408|M.avium_104 SPLSGQGTSVALLGAYILAGELKAAGEDHEAGFANYHREFADYVQRNQWL
Mflv_2621|M.gilvum_PYR-GCK RPHLGQGGCQGIEDAAILA-RFLELADDVPTAFERFEAFRKPRVGMLVRE
Mvan_3960|M.vanbaalenii_PYR-1 RPHLGQGGCQGLEDAAILA-RFVGLSPDLPAAFDRFGAFRRRRVRPLVRE
MMAR_0939|M.marinum_M AARFIGFFATRTRFGLWFRNIAMRTMNIGPLAT-LFAGSVRDD-------
MUL_0690|M.ulcerans_Agy99 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 AAKFIWFFRHPN----PIRPVVSQRCDAHDELR-PAGDAVRRQ-------
Rv0575c|M.tuberculosis_H37Rv AAKFIWFFATRTRFGLWFRNVAMRTMNFGPLAT-LFAGSVRDD-------
MSMEG_1980|M.smegmatis_MC2_155 ARRYLAVFIPKTNLGIAFRDLCMRVVNAVPWTDRLLARTFSDD-------
MAB_2678|M.abscessus_ATCC_1997 ALTASGTLVPKSRLGLCTLVHGARILGHLPSSLTRSLSRLVAARRINIHD
MAV_1408|M.avium_104 VVDN----IPG----------GAPIP-------QEVFERIVAS-------
Mflv_2621|M.gilvum_PYR-GCK AQTLGRIVNVRPAVLSGLAGRATALIPERMVTAHLAWIAAGSA-------
Mvan_3960|M.vanbaalenii_PYR-1 SAAIGRIVNLRPAFLSGVASRASALIPEWAVASHLASIAAGSA-------
MMAR_0939|M.marinum_M -FELPDYDLA---
MUL_0690|M.ulcerans_Agy99 -------------
Mb0590c|M.bovis_AF2122/97 -RA----------
Rv0575c|M.tuberculosis_H37Rv -FELPDYTW----
MSMEG_1980|M.smegmatis_MC2_155 -FALPEYRL----
MAB_2678|M.abscessus_ATCC_1997 TFALRDYQGLISR
MAV_1408|M.avium_104 -ITLKDY------
Mflv_2621|M.gilvum_PYR-GCK -FVLPTAADLAR-
Mvan_3960|M.vanbaalenii_PYR-1 -FILPTAGDVGG-