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M. ulcerans Agy99 MUL_4818 (-)

annotation: GntR family transcriptional regulator
coordinates: 5338348 - 5339127
length: 259

LSEPKILDHRYLQVARTLRKEIVDGIYPVGSQLPTEHELCDRFAVSRYTIREALRRLREDNLVSSRPRTG
TLVVPRPSSDSYVQHVMSINDLLAFATGTRFVIESIAMATIDDEVSAQTGLASGEQWLSVCGFRRAENAE
PAEPALCRTQYYINRAFAAVGRLLHRHDGPIFPLIEDLFGLGIVEVQQEIAAVSISPALAHGLQVEPGSA
ALQIRRAYVTSDEQVAQVTLNTHPASRFRHSMTMRRLRGETGSSGVTDQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4818--100% (259)GntR family transcriptional regulator
M. ulcerans Agy99MUL_3201-2e-1327.00% (237) GntR family transcriptional regulator
M. ulcerans Agy99MUL_0525-2e-1330.00% (230) transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0816c-2e-1226.64% (244) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_1785-2e-9569.71% (241) regulatory protein GntR, HTH
M. tuberculosis H37RvRv0792c-2e-1226.64% (244) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2272c-2e-0936.71% (79) putative transcriptional regulator, GntR
M. marinum MMMAR_0304-1e-145100.00% (259) GntR family transcriptional regulator
M. avium 104MAV_5211-6e-9669.80% (245) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_5630-2e-9669.83% (242) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_0099-6e-9771.37% (241) transcriptional regulator, GntR family protein
M. vanbaalenii PYR-1Mvan_4965-4e-9570.54% (241) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mb0816c|M.bovis_AF2122/97           MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERE
Rv0792c|M.tuberculosis_H37Rv        MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERE
MUL_4818|M.ulcerans_Agy99           ------------MSEPKILDHRYLQVARTLRKEIVDGIYPVGSQLPTEHE
MMAR_0304|M.marinum_M               ------------MSEPKILDHRYLQVARTLRKEIVDGIYPVGSQLPTEHE
Mflv_1785|M.gilvum_PYR-GCK          ------------MTTT-AGDHRYLQVARTLRKEIVDGVYPVGSQLPTEHE
Mvan_4965|M.vanbaalenii_PYR-1       ------------MTAT-AGDHRYLQVARALRKEIVDGIYPVGSQLPTEHE
MSMEG_5630|M.smegmatis_MC2_155      ------------MTVS-PAEHRYLQVARTLRKEIVDGVYPVGSHLPTEHE
TH_0099|M.thermoresistible__bu      ------------MTVS-PADHRYLQVARILRKEIVDGVYPVGSQLPTEHE
MAV_5211|M.avium_104                ------------MPQTISGDHRYLQIARALRKEIVDGVYPVGSQLPTEHQ
MAB_2272c|M.abscessus_ATCC_199      -------------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPE
                                                   .        *::. *: :*:.   . *.::*:* :

Mb0816c|M.bovis_AF2122/97           LIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTI
Rv0792c|M.tuberculosis_H37Rv        LIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTI
MUL_4818|M.ulcerans_Agy99           LCDRFAVSRYTIREALRRLREDNLVSSRPRTGTLVVPRPSSDSYVQHVMS
MMAR_0304|M.marinum_M               LCDRFAVSRYTIREALRRLREDNLVSSRPRTGTLVVPRPSSDSYVQHVMS
Mflv_1785|M.gilvum_PYR-GCK          LCERFAVSRYTIREALRRLREDNLVASRPRAGTLVVPRPTTNAYAQDVVA
Mvan_4965|M.vanbaalenii_PYR-1       LCERFAVSRYTIREALRRLRDDNLVESRPRAGTLVVPRPSTNSYAQDVVS
MSMEG_5630|M.smegmatis_MC2_155      LCERFEVSRYTIREALRRLRDDNLVESRPRAGTTVVPRPTTNSYAQDVMS
TH_0099|M.thermoresistible__bu      LSERFSVSRYTIREALRRLREDNLISSRPRAGTMVVPRPSSHAYAQDVMS
MAV_5211|M.avium_104                LCERFAVSRYTIREALRRLREDNLVASRPRAGTRVVPRPASSSYAQDAMS
MAB_2272c|M.abscessus_ATCC_199      LCELTGTSRNTIREAVQALVHAGMLERRQGSGTYVLSLGGSSAIADYFAA
                                    * :    ** *:* *:  *   . :  *   ** *               

Mb0816c|M.bovis_AF2122/97           TEVLLSCGVTPQVDVLSHQTGP---APQRISETLGLV---EVLCIRRRIR
Rv0792c|M.tuberculosis_H37Rv        TEVLLSCGVTPQVDVLSHQTGP---APQRISETLGLV---EVLCIRRRIR
MUL_4818|M.ulcerans_Agy99           INDLLAFATGTRFVIESIAMAT---IDDEVSAQTGLASGEQWLSVCGFRR
MMAR_0304|M.marinum_M               INDLLAFATGTRFVIESIAMAT---IDDEVSAQTGLASGEQWLSVCGFRR
Mflv_1785|M.gilvum_PYR-GCK          IDDLLAFAQGARFAIETNAMVT---IDDELADLTGLPVGTEWLAVSGYRR
Mvan_4965|M.vanbaalenii_PYR-1       IDDLLAFAQGAQFSIETNGMVT---VDDALAERTGLAPGSEWFAVSGYRR
MSMEG_5630|M.smegmatis_MC2_155      INDLLAFATGAQFTIDSNAMVT---IDDELAERTGLPVDEEWLAVRGYRQ
TH_0099|M.thermoresistible__bu      INDLLAFATGAKFAIESVAMVT---IDDELADRTGLTVDEQWLAVLGYRQ
MAV_5211|M.avium_104                IDDLLAFAAGAQLTIESNAMVT---IDDELAARTGLEPGTQWLSVRGYRQ
MAB_2272c|M.abscessus_ATCC_199      ANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAPHHVE
                                     :          . : :    .     : :    .*    : :      .

Mb0816c|M.bovis_AF2122/97           TGDQP----LALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRI
Rv0792c|M.tuberculosis_H37Rv        TGDQP----LALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRI
MUL_4818|M.ulcerans_Agy99           AENAEPAEPALCRTQYYINRAFAAVGRLLHR--HDGPIFPLIEDLFGLGI
MMAR_0304|M.marinum_M               AENAEPAEPALCRTQYYINRAFAAVGRLLHR--HDGPIFPLIEDLFGLGI
Mflv_1785|M.gilvum_PYR-GCK          IDDET---APFCRTEYFINRSFAAVGRHLQR--HTGPIFPLIEDLFGVSV
Mvan_4965|M.vanbaalenii_PYR-1       ADDDT---APICRTEYFINRSFAAVGRLLQR--HTGPIFPLIEDLFGVSI
MSMEG_5630|M.smegmatis_MC2_155      AEGNK---PPVCRTEYYINRSFAAVGRLLQR--HTGPIFPLIEDLFGVSV
TH_0099|M.thermoresistible__bu      ADGSD---TPVCRTEYYINRAFAAVGRLLPS--HTGPIFPLIEDMFGVSI
MAV_5211|M.avium_104                ADGAP---VPICRTEYYINRSFAAVGRLLQR--HAGPIFPLIEDLFGVSV
MAB_2272c|M.abscessus_ATCC_199      PHNVE----EAISTDIAVHRAVVAAS-------HNALYLELYDSLLGLMD
                                      .          *         *.        .      : :  :*:  

Mb0816c|M.bovis_AF2122/97           AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
Rv0792c|M.tuberculosis_H37Rv        AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
MUL_4818|M.ulcerans_Agy99           VEVQQEIAAVSISPALAHGLQVEPGSAALQIRRAYVTSDEQVAQVTLNTH
MMAR_0304|M.marinum_M               VEVQQEIAAVSISPALAHGLQVEPGSAALQIRRAYVTSDEQVAQVTLNTH
Mflv_1785|M.gilvum_PYR-GCK          VEVHQEISAVVLGSELAERLQISPGTAALRMKRSYTTSDGEVAQVTVNTH
Mvan_4965|M.vanbaalenii_PYR-1       VEVHQEISAVVLDADLAAHLQAEVGAAALQMQRTYTTSDGEIAQVTVNTH
MSMEG_5630|M.smegmatis_MC2_155      VEVHQQITAVLVDTDLAELLKVSPGTAALQMQRTYTTSDGEIAQVTVNTH
TH_0099|M.thermoresistible__bu      IEVHQQISAVLLGPGLADRLRDEAGSPALEMQRTYKTSDGDVAQVTVNTH
MAV_5211|M.avium_104                AQLHQEIAAVLLSPELADGLGAEAGTAALQMRRTYTTSDGEVAQVTINTH
MAB_2272c|M.abscessus_ATCC_199      HYMRGNPIGAECSFEHEHTRLVES-VIAGDIGGATSATEQLFAELRLSRD
                                         :  ..  .              .  :  :  :.:    :: :  .

Mb0816c|M.bovis_AF2122/97           RPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv        RPERYQFSVTLPRTLPGSGAGIIEKRDFA
MUL_4818|M.ulcerans_Agy99           PASRFRHSMTMRRLRGETGSSGVTDQ---
MMAR_0304|M.marinum_M               PASRFRHSMTMRRLRGETGSSGVTDQ---
Mflv_1785|M.gilvum_PYR-GCK          PSSRFRHAMTMRRVRDAP-----------
Mvan_4965|M.vanbaalenii_PYR-1       PSSRFRHSMTMRRVRDTA-----------
MSMEG_5630|M.smegmatis_MC2_155      PSGRYRHSMTMRRVKG-------------
TH_0099|M.thermoresistible__bu      PASRFRHSMTMRRVKP-------------
MAV_5211|M.avium_104                LSPNFRYAMTMRRVTGQAG----------
MAB_2272c|M.abscessus_ATCC_199      QPGRNFPHHPHD-----------------
                                     . .     .