For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_6776 (-)

annotation: transcriptional regulator, LysR family protein
coordinates: 6825514 - 6826359
length: 281

VFEVTGRLLSVSKAAAELSVTPAAVSRQVRALERFLGVRLFNRAPAGLELTPAGARYLAEIGPLFTALEK
ATEAVRPGARSTTLKIRSPATFAVRWLIPRFASFHRLHPDIDVQLTTSPAPIDLEREDLDAGVQLGDGDW
PGVRTQPLIPNELVPVVAPHARTGLTDPAALAEATLLHSLARIDDWARWLRAAGVDTTGAYSGMKYETSL
LAYQAAIEGHGVAIAQKALVQRELADGSLVMPFDFVLDEGRRTYYFVWHAQRRPSAALSAFREWLTTAVD
A
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6776--100% (281)transcriptional regulator, LysR family protein
M. smegmatis MC2 155MSMEG_1391-1e-1427.14% (280) transcriptional regulator, LysR family protein
M. smegmatis MC2 155MSMEG_1985-2e-1126.97% (152) transcriptional regulator, LysR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0384-2e-0826.72% (247) LysR family transcriptional regulator
M. gilvum PYR-GCKMflv_1470-2e-0928.26% (138) LysR family transcriptional regulator
M. tuberculosis H37RvRv0377-2e-0826.72% (247) LysR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0993c-1e-0931.30% (115) LysR family transcriptional regulator
M. marinum MMMAR_4902-5e-0826.67% (180) putative regulatory protein
M. avium 104MAV_2789-5e-0838.46% (78) transcriptional regulator, LysR family protein
M. thermoresistible (build 8)TH_0172-7e-0824.88% (201) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_0119-8e-0828.25% (177) LysR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5301-2e-1030.43% (138) LysR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1470|M.gilvum_PYR-GCK          MQLPPPAMIKTAGWFCENAEMSPLGRRPSADDLLVLLAVGRTGKYTSAAD
Mvan_5301|M.vanbaalenii_PYR-1       MQLPRAAMAKTAPGICKNAEMSSPVRRPSADDLLVLLAVGRTGRYTTAAD
Mb0384|M.bovis_AF2122/97            ---------------------------MTPAQLRAYSAVVRLGSVRAAAA
Rv0377|M.tuberculosis_H37Rv         ---------------------------MTPAQLRAYSAVVRLGSVRAAAA
MUL_0119|M.ulcerans_Agy99           --------------------------------------MVRLGSVRAAAT
TH_0172|M.thermoresistible__bu      ---------------------------MTPAQLRAFSAVVRLGSVRAAAQ
MSMEG_6776|M.smegmatis_MC2_155      ----------------------------------MFEVTGRLLSVSKAAA
MMAR_4902|M.marinum_M               --------------------------MIDPHRLRILRAVVAEGSIGGAAA
MAV_2789|M.avium_104                -----------MKDLCSSGMDVVQAGRVELRHLRAFEAVARLESFTLAAQ
MAB_0993c|M.abscessus_ATCC_199      -------------------MAETAPLDLDLRLVRYFTVVAEQRHFGRAST
                                                                                   *: 

Mflv_1470|M.gilvum_PYR-GCK          ELGLNHTTISRRIAALEQAMGGRVLARVAGGWELTDLGREALAAAEVVET
Mvan_5301|M.vanbaalenii_PYR-1       ELGLNHTTISRRIAALERAMGGRVLARVAGGWELTDLGREALAAAEAVET
Mb0384|M.bovis_AF2122/97            ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG
Rv0377|M.tuberculosis_H37Rv         ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG
MUL_0119|M.ulcerans_Agy99           ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASGAVEILG
TH_0172|M.thermoresistible__bu      ELGMSDAGISMHIAQLRKELDDPLFHRTKNGLSFTPGGLRLASRAVDILG
MSMEG_6776|M.smegmatis_MC2_155      ELSVTPAAVSRQVRALERFLGVRLFNRAPAGLELTPAGARYLAEIGPLFT
MMAR_4902|M.marinum_M               ALGCTPSAVSQHIAVLQREIGLTLVEKVGRGIAPTDAGATLAAESAAVFD
MAV_2789|M.avium_104                ELSITQPALSRTIKQLEDALEASLLDRTSRHVATTPAGRVFLGHVERILT
MAB_0993c|M.abscessus_ATCC_199      ELRVAQPSLSRQISRLEQQLGVRLLDRTPQGTTLTEAGEVFLPKAKTLLR
                                     *    . :*  :  *.  :   :. :.      *  *         :  

Mflv_1470|M.gilvum_PYR-GCK          AVRSLATDPAGQRALEG-VVRISATDGFSAYIAAPAAAAVQRRHPGVAVE
Mvan_5301|M.vanbaalenii_PYR-1       AVRSLATDAAGQRALEG-VVRISATDGFSAYIAAPAAAAVQRRHPKVAVE
Mb0384|M.bovis_AF2122/97            LQQQTAIEVTEAAHGRR-LLRIAASSAFAEHAAPGLIELFSSRADDLSVE
Rv0377|M.tuberculosis_H37Rv         LQQQTAIEVTEAAHGRR-LLRIAASSAFAEHAAPGLIELFSSRADDLSVE
MUL_0119|M.ulcerans_Agy99           LQQQTAIEVTEAAHGRR-LLRIAASSTFAEHAAPGLIELFSSRADDLSVE
TH_0172|M.thermoresistible__bu      LQRQTAIEVTEAAHGRR-LLRIAASHAFAEHAAPGLIDLFSSRADDLSVE
MSMEG_6776|M.smegmatis_MC2_155      ALEK-ATEAVRPGARST-TLKIRSPATFAVRWLIPRFASFHRLHPDIDVQ
MMAR_4902|M.marinum_M               GLSRLDGLVADLRHGRAGTLRVSYFASAGAAWMPAVIATISSEYPAVRLD
MAV_2789|M.avium_104                ELGR---GVDAVRQQAS--IRLGFSWLLPDPWAQDTVARFER-TTRTTVS
MAB_0993c|M.abscessus_ATCC_199      SADQAAAHARAAAQPSH--LTVGYSMG---IIVTPAVLQMRQKHPDADIR
                                                       : :                 .        : 

Mflv_1470|M.gilvum_PYR-GCK          IVAT-TRRATQQRSGMDVEVVVGEPKVRRARALRLSDYCLGLYGSRDYLA
Mvan_5301|M.vanbaalenii_PYR-1       IVAT-TRRATQQRSGLDIEVVVGEPKVHRAKALRLGDYCLGLYASRDYLA
Mb0384|M.bovis_AF2122/97            LSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQIITV
Rv0377|M.tuberculosis_H37Rv         LSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQIITV
MUL_0119|M.ulcerans_Agy99           LSVHPTSQFRDLICARAVDIAIG-PASESSIGSDTSLFVRPFLKYQIITV
TH_0172|M.thermoresistible__bu      LTVEPVSRFRDLLESRAVDVTLG-PAVRE---PGPAIVVRPFLNYQIIAV
MSMEG_6776|M.smegmatis_MC2_155      LTTSPAPIDLE-REDLDAGVQLG-------DGDWPGVRTQPLIPNELVPV
MMAR_4902|M.marinum_M               LRLVELADADDAAPDVEINVAGM-------PGTELSNYDTAALVTEDYVV
MAV_2789|M.avium_104                LIRTDDALGAVQQGRVDIALVRG--------HVTSTAVRIVHLFDEPRVA
MAB_0993c|M.abscessus_ATCC_199      ATHLKWDEARAALLDHRVDAVVA------RLPFSTDQLHVTILYDEPRVV
                                                                                 .   .

Mflv_1470|M.gilvum_PYR-GCK          THGTPATIAELQNHPLVYFI-DSMLQVDDLDLATSFTPAMRESVTSTN--
Mvan_5301|M.vanbaalenii_PYR-1       EHGHPTSVADLQRFPLVYFI-DAMLQVDDLDLATSFAPAMRESVTSTN--
Mb0384|M.bovis_AF2122/97            VAPNSPLAAGIPMPALLRHQ-QWMLGPSAGSVDGEIATMLRGLAIPESQQ
Rv0377|M.tuberculosis_H37Rv         VAPNSPLAAGIPMPALLRHQ-QWMLGPSAGSVDGEIATMLRGLAIPESQQ
MUL_0119|M.ulcerans_Agy99           VAPNSPLAVGIPTPSLLRQQ-QWMLGPPAGSVAGEIATMLRDLAIPESQQ
TH_0172|M.thermoresistible__bu      TSPSNPLAAATPTIAQLRAQ-SWMLGPSAGGIDGDVAAMLRRLEIPEAAQ
MSMEG_6776|M.smegmatis_MC2_155      VAPHAR--TGLTDPAALAEA-TLLHSLARIDDWARWLRAAGVDTTGAYSG
MMAR_4902|M.marinum_M               VVGAGDSLAERDSVTLRELA-GEPWIDNDVARGNCRENLLRACTAAGFTP
MAV_2789|M.avium_104                VCSVHSPLAKRAKLDWAEVP-RWPLVIN--TASGTTGPWSWPAGDGPETI
MAB_0993c|M.abscessus_ATCC_199      LLPSDHPLAQHDSLTLADIANEPMPRIRNADPSWSAYWRVEPRPDGSLAP
                                            .                                         

Mflv_1470|M.gilvum_PYR-GCK          -VFVH----VEATRAAAGIGLLPCFMADR---HDDLVRVLPGQVSLTL-T
Mvan_5301|M.vanbaalenii_PYR-1       -VFVH----VEATRAAAGIGLLPCFMADR---HPDLERVLAAAVSIRL-T
Mb0384|M.bovis_AF2122/97            RIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAG-E
Rv0377|M.tuberculosis_H37Rv         RIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAG-E
MUL_0119|M.ulcerans_Agy99           RIFQSDAAALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAG-E
TH_0172|M.thermoresistible__bu      RIFQSDSAAQEEVQRIGGVTLSIGFAVAKDLAAGRLARIK--GVQATA-E
MSMEG_6776|M.smegmatis_MC2_155      MKYETSLLAYQAAIEGHGVAIAQKALVQRELADGSLVMPFDFVLDEGRRT
MMAR_4902|M.marinum_M               CFRVETHDYVTAVRFVAAGVGLTVVPRLALIDLPAGVRTVAISEPTPRRT
MAV_2789|M.avium_104                VETTNFDEWIESVAADRGIGVIPDVAIRRNVHPGVRFVALRDAPDIPVAL
MAB_0993c|M.abscessus_ATCC_199      DGPVIDAIEDKFEVIASGQAISLSAGAHGSTMRPDIVAVPLEGVEPSHVA
                                                     .                                

Mflv_1470|M.gilvum_PYR-GCK          YWLVTRAETLRRPEVAAVVDAIRDRVRDRHHMLLGAG-------------
Mvan_5301|M.vanbaalenii_PYR-1       YWLVTRAETLRRPEVAAVVDAIRDRVREQHDVLLGAG-------------
Mb0384|M.bovis_AF2122/97            WCVATLAPSARQPAVSELVGFIST-PRCIQAMIRGSGVGVTRFRPKVHVT
Rv0377|M.tuberculosis_H37Rv         WCVATLAPSARQPAVSELVGFIST-PRCIQAMIPGSGVGVTRFRPKVHVT
MUL_0119|M.ulcerans_Agy99           WCVATLPPAARQPAVSELVRFITT-PRCIQAMIRGSGVGVTRFRPKMHVT
TH_0172|M.thermoresistible__bu      WCVSTLSSAARQPAASELVRFITT-PRCTQAMIRGTSEGVTRFRPKVHVT
MSMEG_6776|M.smegmatis_MC2_155      YYFVWHAQRRPSAALSAFREWLTTAVDA----------------------
MMAR_4902|M.marinum_M               IVVRRHHRARNNVVAGRVLELIHQQAVRTHGPAVGALA------------
MAV_2789|M.avium_104                AFVKRASGPVLRRFIEAAVDAAANQ-------------------------
MAB_0993c|M.abscessus_ATCC_199      IATRADDRGRLVAAFRKVAQAVLTGPG-----------------------
                                                                                      

Mflv_1470|M.gilvum_PYR-GCK          ---
Mvan_5301|M.vanbaalenii_PYR-1       ---
Mb0384|M.bovis_AF2122/97            LWS
Rv0377|M.tuberculosis_H37Rv         LWS
MUL_0119|M.ulcerans_Agy99           LWS
TH_0172|M.thermoresistible__bu      LWS
MSMEG_6776|M.smegmatis_MC2_155      ---
MMAR_4902|M.marinum_M               ---
MAV_2789|M.avium_104                ---
MAB_0993c|M.abscessus_ATCC_199      ---