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VFEVTGRLLSVSKAAAELSVTPAAVSRQVRALERFLGVRLFNRAPAGLELTPAGARYLAEIGPLFTALEK ATEAVRPGARSTTLKIRSPATFAVRWLIPRFASFHRLHPDIDVQLTTSPAPIDLEREDLDAGVQLGDGDW PGVRTQPLIPNELVPVVAPHARTGLTDPAALAEATLLHSLARIDDWARWLRAAGVDTTGAYSGMKYETSL LAYQAAIEGHGVAIAQKALVQRELADGSLVMPFDFVLDEGRRTYYFVWHAQRRPSAALSAFREWLTTAVD A
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6776 | - | - | 100% (281) | transcriptional regulator, LysR family protein |
M. smegmatis MC2 155 | MSMEG_1391 | - | 1e-14 | 27.14% (280) | transcriptional regulator, LysR family protein |
M. smegmatis MC2 155 | MSMEG_1985 | - | 2e-11 | 26.97% (152) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0384 | - | 2e-08 | 26.72% (247) | LysR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_1470 | - | 2e-09 | 28.26% (138) | LysR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0377 | - | 2e-08 | 26.72% (247) | LysR family transcriptional regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0993c | - | 1e-09 | 31.30% (115) | LysR family transcriptional regulator |
M. marinum M | MMAR_4902 | - | 5e-08 | 26.67% (180) | putative regulatory protein |
M. avium 104 | MAV_2789 | - | 5e-08 | 38.46% (78) | transcriptional regulator, LysR family protein |
M. thermoresistible (build 8) | TH_0172 | - | 7e-08 | 24.88% (201) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
M. ulcerans Agy99 | MUL_0119 | - | 8e-08 | 28.25% (177) | LysR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_5301 | - | 2e-10 | 30.43% (138) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1470|M.gilvum_PYR-GCK MQLPPPAMIKTAGWFCENAEMSPLGRRPSADDLLVLLAVGRTGKYTSAAD Mvan_5301|M.vanbaalenii_PYR-1 MQLPRAAMAKTAPGICKNAEMSSPVRRPSADDLLVLLAVGRTGRYTTAAD Mb0384|M.bovis_AF2122/97 ---------------------------MTPAQLRAYSAVVRLGSVRAAAA Rv0377|M.tuberculosis_H37Rv ---------------------------MTPAQLRAYSAVVRLGSVRAAAA MUL_0119|M.ulcerans_Agy99 --------------------------------------MVRLGSVRAAAT TH_0172|M.thermoresistible__bu ---------------------------MTPAQLRAFSAVVRLGSVRAAAQ MSMEG_6776|M.smegmatis_MC2_155 ----------------------------------MFEVTGRLLSVSKAAA MMAR_4902|M.marinum_M --------------------------MIDPHRLRILRAVVAEGSIGGAAA MAV_2789|M.avium_104 -----------MKDLCSSGMDVVQAGRVELRHLRAFEAVARLESFTLAAQ MAB_0993c|M.abscessus_ATCC_199 -------------------MAETAPLDLDLRLVRYFTVVAEQRHFGRAST *: Mflv_1470|M.gilvum_PYR-GCK ELGLNHTTISRRIAALEQAMGGRVLARVAGGWELTDLGREALAAAEVVET Mvan_5301|M.vanbaalenii_PYR-1 ELGLNHTTISRRIAALERAMGGRVLARVAGGWELTDLGREALAAAEAVET Mb0384|M.bovis_AF2122/97 ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG Rv0377|M.tuberculosis_H37Rv ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILG MUL_0119|M.ulcerans_Agy99 ELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASGAVEILG TH_0172|M.thermoresistible__bu ELGMSDAGISMHIAQLRKELDDPLFHRTKNGLSFTPGGLRLASRAVDILG MSMEG_6776|M.smegmatis_MC2_155 ELSVTPAAVSRQVRALERFLGVRLFNRAPAGLELTPAGARYLAEIGPLFT MMAR_4902|M.marinum_M ALGCTPSAVSQHIAVLQREIGLTLVEKVGRGIAPTDAGATLAAESAAVFD MAV_2789|M.avium_104 ELSITQPALSRTIKQLEDALEASLLDRTSRHVATTPAGRVFLGHVERILT MAB_0993c|M.abscessus_ATCC_199 ELRVAQPSLSRQISRLEQQLGVRLLDRTPQGTTLTEAGEVFLPKAKTLLR * . :* : *. : :. :. * * : Mflv_1470|M.gilvum_PYR-GCK AVRSLATDPAGQRALEG-VVRISATDGFSAYIAAPAAAAVQRRHPGVAVE Mvan_5301|M.vanbaalenii_PYR-1 AVRSLATDAAGQRALEG-VVRISATDGFSAYIAAPAAAAVQRRHPKVAVE Mb0384|M.bovis_AF2122/97 LQQQTAIEVTEAAHGRR-LLRIAASSAFAEHAAPGLIELFSSRADDLSVE Rv0377|M.tuberculosis_H37Rv LQQQTAIEVTEAAHGRR-LLRIAASSAFAEHAAPGLIELFSSRADDLSVE MUL_0119|M.ulcerans_Agy99 LQQQTAIEVTEAAHGRR-LLRIAASSTFAEHAAPGLIELFSSRADDLSVE TH_0172|M.thermoresistible__bu LQRQTAIEVTEAAHGRR-LLRIAASHAFAEHAAPGLIDLFSSRADDLSVE MSMEG_6776|M.smegmatis_MC2_155 ALEK-ATEAVRPGARST-TLKIRSPATFAVRWLIPRFASFHRLHPDIDVQ MMAR_4902|M.marinum_M GLSRLDGLVADLRHGRAGTLRVSYFASAGAAWMPAVIATISSEYPAVRLD MAV_2789|M.avium_104 ELGR---GVDAVRQQAS--IRLGFSWLLPDPWAQDTVARFER-TTRTTVS MAB_0993c|M.abscessus_ATCC_199 SADQAAAHARAAAQPSH--LTVGYSMG---IIVTPAVLQMRQKHPDADIR : : . : Mflv_1470|M.gilvum_PYR-GCK IVAT-TRRATQQRSGMDVEVVVGEPKVRRARALRLSDYCLGLYGSRDYLA Mvan_5301|M.vanbaalenii_PYR-1 IVAT-TRRATQQRSGLDIEVVVGEPKVHRAKALRLGDYCLGLYASRDYLA Mb0384|M.bovis_AF2122/97 LSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQIITV Rv0377|M.tuberculosis_H37Rv LSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQIITV MUL_0119|M.ulcerans_Agy99 LSVHPTSQFRDLICARAVDIAIG-PASESSIGSDTSLFVRPFLKYQIITV TH_0172|M.thermoresistible__bu LTVEPVSRFRDLLESRAVDVTLG-PAVRE---PGPAIVVRPFLNYQIIAV MSMEG_6776|M.smegmatis_MC2_155 LTTSPAPIDLE-REDLDAGVQLG-------DGDWPGVRTQPLIPNELVPV MMAR_4902|M.marinum_M LRLVELADADDAAPDVEINVAGM-------PGTELSNYDTAALVTEDYVV MAV_2789|M.avium_104 LIRTDDALGAVQQGRVDIALVRG--------HVTSTAVRIVHLFDEPRVA MAB_0993c|M.abscessus_ATCC_199 ATHLKWDEARAALLDHRVDAVVA------RLPFSTDQLHVTILYDEPRVV . . Mflv_1470|M.gilvum_PYR-GCK THGTPATIAELQNHPLVYFI-DSMLQVDDLDLATSFTPAMRESVTSTN-- Mvan_5301|M.vanbaalenii_PYR-1 EHGHPTSVADLQRFPLVYFI-DAMLQVDDLDLATSFAPAMRESVTSTN-- Mb0384|M.bovis_AF2122/97 VAPNSPLAAGIPMPALLRHQ-QWMLGPSAGSVDGEIATMLRGLAIPESQQ Rv0377|M.tuberculosis_H37Rv VAPNSPLAAGIPMPALLRHQ-QWMLGPSAGSVDGEIATMLRGLAIPESQQ MUL_0119|M.ulcerans_Agy99 VAPNSPLAVGIPTPSLLRQQ-QWMLGPPAGSVAGEIATMLRDLAIPESQQ TH_0172|M.thermoresistible__bu TSPSNPLAAATPTIAQLRAQ-SWMLGPSAGGIDGDVAAMLRRLEIPEAAQ MSMEG_6776|M.smegmatis_MC2_155 VAPHAR--TGLTDPAALAEA-TLLHSLARIDDWARWLRAAGVDTTGAYSG MMAR_4902|M.marinum_M VVGAGDSLAERDSVTLRELA-GEPWIDNDVARGNCRENLLRACTAAGFTP MAV_2789|M.avium_104 VCSVHSPLAKRAKLDWAEVP-RWPLVIN--TASGTTGPWSWPAGDGPETI MAB_0993c|M.abscessus_ATCC_199 LLPSDHPLAQHDSLTLADIANEPMPRIRNADPSWSAYWRVEPRPDGSLAP . Mflv_1470|M.gilvum_PYR-GCK -VFVH----VEATRAAAGIGLLPCFMADR---HDDLVRVLPGQVSLTL-T Mvan_5301|M.vanbaalenii_PYR-1 -VFVH----VEATRAAAGIGLLPCFMADR---HPDLERVLAAAVSIRL-T Mb0384|M.bovis_AF2122/97 RIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAG-E Rv0377|M.tuberculosis_H37Rv RIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAG-E MUL_0119|M.ulcerans_Agy99 RIFQSDAAALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAG-E TH_0172|M.thermoresistible__bu RIFQSDSAAQEEVQRIGGVTLSIGFAVAKDLAAGRLARIK--GVQATA-E MSMEG_6776|M.smegmatis_MC2_155 MKYETSLLAYQAAIEGHGVAIAQKALVQRELADGSLVMPFDFVLDEGRRT MMAR_4902|M.marinum_M CFRVETHDYVTAVRFVAAGVGLTVVPRLALIDLPAGVRTVAISEPTPRRT MAV_2789|M.avium_104 VETTNFDEWIESVAADRGIGVIPDVAIRRNVHPGVRFVALRDAPDIPVAL MAB_0993c|M.abscessus_ATCC_199 DGPVIDAIEDKFEVIASGQAISLSAGAHGSTMRPDIVAVPLEGVEPSHVA . Mflv_1470|M.gilvum_PYR-GCK YWLVTRAETLRRPEVAAVVDAIRDRVRDRHHMLLGAG------------- Mvan_5301|M.vanbaalenii_PYR-1 YWLVTRAETLRRPEVAAVVDAIRDRVREQHDVLLGAG------------- Mb0384|M.bovis_AF2122/97 WCVATLAPSARQPAVSELVGFIST-PRCIQAMIRGSGVGVTRFRPKVHVT Rv0377|M.tuberculosis_H37Rv WCVATLAPSARQPAVSELVGFIST-PRCIQAMIPGSGVGVTRFRPKVHVT MUL_0119|M.ulcerans_Agy99 WCVATLPPAARQPAVSELVRFITT-PRCIQAMIRGSGVGVTRFRPKMHVT TH_0172|M.thermoresistible__bu WCVSTLSSAARQPAASELVRFITT-PRCTQAMIRGTSEGVTRFRPKVHVT MSMEG_6776|M.smegmatis_MC2_155 YYFVWHAQRRPSAALSAFREWLTTAVDA---------------------- MMAR_4902|M.marinum_M IVVRRHHRARNNVVAGRVLELIHQQAVRTHGPAVGALA------------ MAV_2789|M.avium_104 AFVKRASGPVLRRFIEAAVDAAANQ------------------------- MAB_0993c|M.abscessus_ATCC_199 IATRADDRGRLVAAFRKVAQAVLTGPG----------------------- Mflv_1470|M.gilvum_PYR-GCK --- Mvan_5301|M.vanbaalenii_PYR-1 --- Mb0384|M.bovis_AF2122/97 LWS Rv0377|M.tuberculosis_H37Rv LWS MUL_0119|M.ulcerans_Agy99 LWS TH_0172|M.thermoresistible__bu LWS MSMEG_6776|M.smegmatis_MC2_155 --- MMAR_4902|M.marinum_M --- MAV_2789|M.avium_104 --- MAB_0993c|M.abscessus_ATCC_199 ---