For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AETAPLDLDLRLVRYFTVVAEQRHFGRASTELRVAQPSLSRQISRLEQQLGVRLLDRTPQGTTLTEAGEV FLPKAKTLLRSADQAAAHARAAAQPSHLTVGYSMGIIVTPAVLQMRQKHPDADIRATHLKWDEARAALLD HRVDAVVARLPFSTDQLHVTILYDEPRVVLLPSDHPLAQHDSLTLADIANEPMPRIRNADPSWSAYWRVE PRPDGSLAPDGPVIDAIEDKFEVIASGQAISLSAGAHGSTMRPDIVAVPLEGVEPSHVAIATRADDRGRL VAAFRKVAQAVLTGPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0993c | - | - | 100% (297) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4409 | - | 8e-25 | 29.11% (292) | hydrogen peroxide-inducible genes activator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 5e-22 | 34.55% (191) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 2e-14 | 30.89% (191) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_1346 | - | 2e-23 | 31.42% (296) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 2e-14 | 30.89% (191) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02041 | oxyR | 5e-17 | 30.32% (188) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 5e-16 | 26.88% (186) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_2838 | - | 4e-20 | 32.98% (188) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_1561 | - | 2e-34 | 36.33% (278) | LysR-family protein trancsriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-15 | 29.90% (194) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 4e-16 | 26.88% (186) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_4518 | - | 2e-23 | 27.47% (273) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0993c|M.abscessus_ATCC_199 -------MAETAPLDLDLRLVRYFTVVAEQRHFGRASTELRVAQPSLSRQ
MSMEG_1561|M.smegmatis_MC2_155 -------MAPSPSRDLDLRKLRYFVAVAEELNFGRAAQRLHIAQPVLSRQ
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
MAV_2838|M.avium_104 --------MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQA
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
Mb0121|M.bovis_AF2122/97 ---------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSA
Rv0117|M.tuberculosis_H37Rv ---------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSA
Mflv_1346|M.gilvum_PYR-GCK ---------------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQ
Mvan_4518|M.vanbaalenii_PYR-1 ---------------MTLRQLRYFAVLGHELNYRRAAEKLFITQPALSTA
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
: : * .: . : *: : * **
MAB_0993c|M.abscessus_ATCC_199 ISRLEQQLGVRLLDRTPQGTTLTEAGEVFLPKAKTLLRSADQAAAHARAA
MSMEG_1561|M.smegmatis_MC2_155 IRAFENELGVQLFVRGSNGTQLSAAGAQLLQDAKVLLDDAKALQQRLFQA
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
MAV_2838|M.avium_104 LAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGS
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
Mb0121|M.bovis_AF2122/97 IAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAV
Rv0117|M.tuberculosis_H37Rv IAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAV
Mflv_1346|M.gilvum_PYR-GCK IRQLEREVGADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRI
Mvan_4518|M.vanbaalenii_PYR-1 IKQLEHQFGVVLFHRNTREVALTDLGAAWLPQVQQALSGVDAVVDNLIML
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :* .. *. * :: * : :
MAB_0993c|M.abscessus_ATCC_199 AQPS--HLTVGYSMGII---VTPAVLQMRQKHPDADIRAT-HLKWDEARA
MSMEG_1561|M.smegmatis_MC2_155 ASPSR-TVTVGVMPGLR---ATAAAAAFGAAGPGRRAIVR-QVSWAEQVE
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVV-EDQTEHLLT
MAV_2838|M.avium_104 ADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVT-EDQTERLLA
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVI-EDQTERLLT
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVI-EDQTERLLT
Mb0121|M.bovis_AF2122/97 RSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAKVQVCS-RLAATELYR
Rv0117|M.tuberculosis_H37Rv RSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAKVQVCS-RLAATELYR
Mflv_1346|M.gilvum_PYR-GCK GTGAEGRLVVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQLA
Mvan_4518|M.vanbaalenii_PYR-1 SGTRRGVLRVGYLIGTGADLLFRLVRHFEAAYPDVTVEPI-EFDFADPTA
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLR-QLYPDALTD
.* .
MAB_0993c|M.abscessus_ATCC_199 ALLDHRVDAVVAR-LPFSTDQLHVTILYDEPRVVLLPSDHPLAQHDSLTL
MSMEG_1561|M.smegmatis_MC2_155 AVRSGDVDVVYAREVDGNTPGLGSAPLLQEQYFAVLPADDPLATRPSLTM
MLBr_02041|M.leprae_Br4923 ALREGALDAAMIA-LPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPT
MAV_2838|M.avium_104 VLREGALDAALIA-LPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPA
MMAR_2756|M.marinum_M ALREGSLDTALIA-LPADYGGLTEIPIYEEDFVLALPPGHPMADRHGVPV
MUL_2998|M.ulcerans_Agy99 ALREGSLDTALIA-LPADYGGLTEIPIYEEDFVLALPPGHPMADRHGVPV
Mb0121|M.bovis_AF2122/97 RLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTSTLVW
Rv0117|M.tuberculosis_H37Rv RLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTSTLVW
Mflv_1346|M.gilvum_PYR-GCK ALHAKDIDLALMR-PPVDDPALTAVSLRRDRLLVALPAGHRCADRDEVSL
Mvan_4518|M.vanbaalenii_PYR-1 GLADGTTEVAIIR-PPVDLPEHRMLILDSESWVACLPRDHRLAERREVEI
TH_3504|M.thermoresistible__bu AVFDGTVQLGLRR-GVVPTPELATAVIGYHRVRVAFVDSHPLAARESVDI
: : : . . . :
MAB_0993c|M.abscessus_ATCC_199 ADIANEPMPRIRNADPSWSAYWRVEPRPDGSLAP-DGPVIDAIEDKFEVI
MSMEG_1561|M.smegmatis_MC2_155 DDLA----DRLLLQDPAILAEVRRTAAPGQRWAP-PPTAVHTVEDKLEHV
MLBr_02041|M.leprae_Br4923 TALAQLPLLLLDEGHCLRDQTLDICRKSGVQAEL-ANTRAASLATAVQCV
MAV_2838|M.avium_104 TALADLPLLLLDEGHCLRDQALDVCHKAGVRAEL-ANTRAASLATAVQCV
MMAR_2756|M.marinum_M AALSELPLLLLDEGHCLRDQALDVCQNAGVRAEL-ADTRAASLATAVQCV
MUL_2998|M.ulcerans_Agy99 AALSELPLLLLDEGHCLRDQALDVCQNAGVRAEH-ADTRADSLATAVQCV
Mb0121|M.bovis_AF2122/97 RDAAQLPLALLTADMRDR-QVIDAAFADHAVSAI-PQVETDSVASLFAQV
Rv0117|M.tuberculosis_H37Rv RDAAQLPLALLTADMRDR-QVIDAAFADHAVSAI-PQVETDSVASLFAQV
Mflv_1346|M.gilvum_PYR-GCK ADLRDEDFISHAGGGRSRMSALLAALCADAGFSPRIRDEVDETSTLVTLV
Mvan_4518|M.vanbaalenii_PYR-1 AELLDDPIVCAPLTAGTWRDYWLAMDVRGNRPPT-IAAVAATYEAETTAI
TH_3504|M.thermoresistible__bu TELAREQVALWAPPGTSYYSDFLMGACRRAGFEP--DYVVSRVQGAATVA
MAB_0993c|M.abscessus_ATCC_199 ASGQAISLSAGAHGSTMR-PDIVAVPLEGVEP--SHVAIATRADDR----
MSMEG_1561|M.smegmatis_MC2_155 AAREGFVVMPRSTTDFYRRPDVRAVPVEGLPP--NRVTLIWNAATD----
MLBr_02041|M.leprae_Br4923 TGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSAS
MAV_2838|M.avium_104 TGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDS
MMAR_2756|M.marinum_M NGGLGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLVYRASSGRDEA
MUL_2998|M.ulcerans_Agy99 NGGLGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLVYRASSGRDEA
Mb0121|M.bovis_AF2122/97 ATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATN---A
Rv0117|M.tuberculosis_H37Rv ATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATN---A
Mflv_1346|M.gilvum_PYR-GCK AGGLGVALVPEPTAALEIGGVTYRPLAAKAGATIELLAVYRSADAS----
Mvan_4518|M.vanbaalenii_PYR-1 ARGLGISFTTSSVARFYDRPGIVYVPICDRPPSHTALAWNPADLTP----
TH_3504|M.thermoresistible__bu APLTTGGIAFVTAAAGPTMNGRVQVVDLTPPLLVPVQALWQRHTLS----
. .
MAB_0993c|M.abscessus_ATCC_199 ----GRLVAAFRKVAQAVLTGPG------------
MSMEG_1561|M.smegmatis_MC2_155 ----NPVRDEFITAALACRDETV------------
MLBr_02041|M.leprae_Br4923 YRQIAKIIGELISTEHHVRLVA-------------
MAV_2838|M.avium_104 YRELAGLIGELISSQHQVRLVK-------------
MMAR_2756|M.marinum_M YRQLAAIMGESISNEQQVRLVN-------------
MUL_2998|M.ulcerans_Agy99 YRQLAAIMGESISNEQQVRLVN-------------
Mb0121|M.bovis_AF2122/97 LGPGSPVARALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv LGPGSPVARALITCAQALALNEFFDTQLRGITRRR
Mflv_1346|M.gilvum_PYR-GCK -----PLTAKVVDVLRATV----------------
Mvan_4518|M.vanbaalenii_PYR-1 ---QADALVRHVQSQWSFGDGDNADHG--------
TH_3504|M.thermoresistible__bu -----AIRDRILEGLG-------------------