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STMFSADNLRYFLEVARTGRLNDAARNLGVDHTTVGRRITALEKSIGERLFDRSPGGWQLTEAGADLFPR AETVESAVIAAYETRTSAGPLTGTVSVATTDGFGAFVLAPRLADLRRRHPHLDIEMATATEHRSLSARHF DIAVTLEEPPSRGVLVQALAGYDLRLYATPGYLDDAPPIDELADLARHTLIWYIDALLDVAPLRILGLLP HKQRVAIQTNNITGHWLAARGGLGIAPLPQYIAESDPELTCVLPQEFSVRRRYWMVIPRELRQVGRVRAV AQFLNEVVNDNPYLMAPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1391 | - | - | 100% (299) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_6028 | - | 9e-46 | 35.31% (286) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_1985 | - | 3e-19 | 28.52% (298) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 2e-07 | 29.41% (170) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1470 | - | 5e-45 | 34.02% (291) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-07 | 29.41% (170) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-09 | 29.41% (170) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0993c | - | 2e-12 | 35.90% (117) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 2e-09 | 32.82% (131) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_2838 | - | 2e-11 | 28.74% (247) | hydrogen peroxide-inducible genes activator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 2e-09 | 32.82% (131) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_5301 | - | 8e-46 | 36.01% (286) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2303c|M.bovis_AF2122/97 --------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAAR
Rv2282c|M.tuberculosis_H37Rv --------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAAR
MLBr_02041|M.leprae_Br4923 --------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAAS
MAV_2838|M.avium_104 --------------------MPDKTYQPTIAGLRAFVAVAEKRQFSGAAT
MMAR_2756|M.marinum_M ------------MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAAN
MUL_2998|M.ulcerans_Agy99 -----------------MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAAN
Mflv_1470|M.gilvum_PYR-GCK MQLPPPAMIKTAGWFCENAEMSPLGRRPSADDLLVLLAVGRTGKYTSAAD
Mvan_5301|M.vanbaalenii_PYR-1 MQLPRAAMAKTAPGICKNAEMSSPVRRPSADDLLVLLAVGRTGRYTTAAD
MSMEG_1391|M.smegmatis_MC2_155 -----------------------MSTMFSADNLRYFLEVARTGRLNDAAR
MAB_0993c|M.abscessus_ATCC_199 -------------------MAETAPLDLDLRLVRYFTVVAEQRHFGRAST
. : : . *:
Mb2303c|M.bovis_AF2122/97 ELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLE
Rv2282c|M.tuberculosis_H37Rv ELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLE
MLBr_02041|M.leprae_Br4923 FLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIE
MAV_2838|M.avium_104 ALGVSQSTLSQALAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVE
MMAR_2756|M.marinum_M ALGVSQSTLSQALAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVE
MUL_2998|M.ulcerans_Agy99 ALGVSQSTLSQALAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVE
Mflv_1470|M.gilvum_PYR-GCK ELGLNHTTISRRIAALEQAMGGRVLARVAGGWELTDLGREALAAAEVVET
Mvan_5301|M.vanbaalenii_PYR-1 ELGLNHTTISRRIAALERAMGGRVLARVAGGWELTDLGREALAAAEAVET
MSMEG_1391|M.smegmatis_MC2_155 NLGVDHTTVGRRITALEKSIGERLFDRSPGGWQLTEAGADLFPRAETVES
MAB_0993c|M.abscessus_ATCC_199 ELRVAQPSLSRQISRLEQQLGVRLLDRTPQGTTLTEAGEVFLPKAKTLLR
* : : ::.: :: :* :. :: * . :* * *
Mb2303c|M.bovis_AF2122/97 VADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGT
Rv2282c|M.tuberculosis_H37Rv VADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGT
MLBr_02041|M.leprae_Br4923 AMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPT----
MAV_2838|M.avium_104 AADAFTAAAAGSADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPG----
MMAR_2756|M.marinum_M AVEAFTTAAAGEADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPT----
MUL_2998|M.ulcerans_Agy99 AVEAFTTAAAGEADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPT----
Mflv_1470|M.gilvum_PYR-GCK AVRSLATDPAGQR-ALEGVVRISATDGFSAYIAAPAAAAVQRRHPG----
Mvan_5301|M.vanbaalenii_PYR-1 AVRSLATDAAGQR-ALEGVVRISATDGFSAYIAAPAAAAVQRRHPK----
MSMEG_1391|M.smegmatis_MC2_155 AVIAAYETRTSAG-PLTGTVSVATTDGFGAFVLAPRLADLRRRHPH----
MAB_0993c|M.abscessus_ATCC_199 SADQAAAHARAAAQPSHLTVGYSMG-----IIVTPAVLQMRQKHPD----
. : : . :
Mb2303c|M.bovis_AF2122/97 VPEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVV
Rv2282c|M.tuberculosis_H37Rv VPEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVV
MLBr_02041|M.leprae_Br4923 -LTLRVVEDQTEHLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLA
MAV_2838|M.avium_104 -LTLRVTEDQTERLLAVLREGALDAALIALPAETAGVTAIPIYDEDFVLA
MMAR_2756|M.marinum_M -LTVRVIEDQTERLLTALREGSLDTALIALPADYGGLTEIPIYEEDFVLA
MUL_2998|M.ulcerans_Agy99 -LTVRVIEDQTERLLTALREGSLDTALIALPADYGGLTEIPIYEEDFVLA
Mflv_1470|M.gilvum_PYR-GCK ----VAVEIVATTRRATQQRSGMDVEVVVGEPKVRRARALRLSDYCLGLY
Mvan_5301|M.vanbaalenii_PYR-1 ----VAVEIVATTRRATQQRSGLDIEVVVGEPKVHRAKALRLGDYCLGLY
MSMEG_1391|M.smegmatis_MC2_155 ----LDIEMATATEHRSLSARHFDIAVTLEEPPSRGVLVQALAGYDLRLY
MAB_0993c|M.abscessus_ATCC_199 -ADIRATHLKWDEARAALLDHRVDAVVARLPFSTDQLHVTILYDEPRVVL
* . : :
Mb2303c|M.bovis_AF2122/97 VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQ
Rv2282c|M.tuberculosis_H37Rv VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQ
MLBr_02041|M.leprae_Br4923 LPPGHPLSGK-RRVPTTALAQLPLLLLDEGHCLRDQTLDICRK---SGVQ
MAV_2838|M.avium_104 LPPGHPLAGK-RRVPATALADLPLLLLDEGHCLRDQALDVCHK---AGVR
MMAR_2756|M.marinum_M LPPGHPMADR-HGVPVAALSELPLLLLDEGHCLRDQALDVCQN---AGVR
MUL_2998|M.ulcerans_Agy99 LPPGHPMADR-HGVPVAALSELPLLLLDEGHCLRDQALDVCQN---AGVR
Mflv_1470|M.gilvum_PYR-GCK GSRDYLATHG-TPATIAELQNHPLVYFID-SMLQVDDLDLATS----FTP
Mvan_5301|M.vanbaalenii_PYR-1 ASRDYLAEHG-HPTSVADLQRFPLVYFID-AMLQVDDLDLATS----FAP
MSMEG_1391|M.smegmatis_MC2_155 ATPGYLDDAP-PIDELADLARHTLIWYID-ALLDVAPLRILGL----LPH
MAB_0993c|M.abscessus_ATCC_199 LPSDHPLAQH-DSLTLADIANEPMPRIRNADPSWSAYWRVEPR---PDGS
. .: : .:
Mb2303c|M.bovis_AF2122/97 QAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALN
Rv2282c|M.tuberculosis_H37Rv QAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALN
MLBr_02041|M.leprae_Br4923 AELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPC
MAV_2838|M.avium_104 AELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPR
MMAR_2756|M.marinum_M AELADTRAASLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLAHFAAPT
MUL_2998|M.ulcerans_Agy99 AEHADTRADSLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLTHFAAPT
Mflv_1470|M.gilvum_PYR-GCK AMRESVTSTNVFVHVEATRAAAGIGLLPCFMADRHDDLVRVLPGQVSLT-
Mvan_5301|M.vanbaalenii_PYR-1 AMRESVTSTNVFVHVEATRAAAGIGLLPCFMADRHPDLERVLAAAVSIR-
MSMEG_1391|M.smegmatis_MC2_155 KQRVAIQTNNITGHWLAARGGLGIAPLPQYIAESDPELTCVLPQEFSVR-
MAB_0993c|M.abscessus_ATCC_199 LAPDGPVIDAIEDKFEVIASGQAISLS----AGAHGSTMRPDIVAVPLEG
.. . . ..
Mb2303c|M.bovis_AF2122/97 LRRQLRAIWVG--GRTPPAGAIRDLLSHITSRST-------
Rv2282c|M.tuberculosis_H37Rv LRRQLRAIWVG--GRTPPAGAIRDLLSHITSRST-------
MLBr_02041|M.leprae_Br4923 PGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA-
MAV_2838|M.avium_104 PGRRIGLVFRSSSGRDDSYRELAGLIGELISSQHQVRLVK-
MMAR_2756|M.marinum_M PGRRIGLVYRASSGRDEAYRQLAAIMGESISNEQQVRLVN-
MUL_2998|M.ulcerans_Agy99 PGRRIGLVYRASSGRDEAYRQLAAIMGESISNEQQVRLVN-
Mflv_1470|M.gilvum_PYR-GCK --LTYWLVTRAETLRRPEVAAVVDAIRDRVRDRHHMLLGAG
Mvan_5301|M.vanbaalenii_PYR-1 --LTYWLVTRAETLRRPEVAAVVDAIRDRVREQHDVLLGAG
MSMEG_1391|M.smegmatis_MC2_155 --RRYWMVIPRELRQVGRVRAVAQFLNEVVNDNPYLMAPG-
MAB_0993c|M.abscessus_ATCC_199 VEPSHVAIATRADDRGRLVAAFRKVAQAVLTGPG-------
: .