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VTSSVKPARADATRNREALLAAAEEEFAERGLAASVADIARRAGVAKGTVFRHFPTKEDLIAAIVTAHTA TLSETARSLVDAPDPGAALLEFLTEAADQRRQHDLTFLQAASADDSSVTAARDELHGYVEQLVAAAREAG AIRADVTGTDVFLLMCTPIHVVENLPDPSPDLWQRYLGILFDGLRPEGAHPLPQPPPRLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3807 | - | - | 100% (200) | TetR-type regulator |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 1e-24 | 37.70% (183) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1380 | - | 1e-22 | 35.05% (194) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 5e-20 | 33.15% (181) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 5e-21 | 34.41% (186) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 5e-20 | 33.15% (181) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 1e-19 | 34.76% (187) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 2e-25 | 36.96% (184) | transcriptional regulator TetR |
| M. marinum M | MMAR_0489 | - | 1e-10 | 33.33% (159) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2463 | - | 4e-20 | 34.39% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2712 | - | 8e-10 | 28.82% (170) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1152 | - | 1e-10 | 33.33% (159) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 6e-79 | 73.60% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3807|M.smegmatis_MC2_155 ---------------------MTSSVKPARADATRNREALLAAAEEEFAE
Mvan_1492|M.vanbaalenii_PYR-1 ---------------------MTPPDRPVRADAARNRALLLAAAEEEFAE
Mb0068c|M.bovis_AF2122/97 ---------------------MAPTDRRVRADAARNRARVLEVAYQTFAA
Rv0067c|M.tuberculosis_H37Rv ---------------------MAPTDRRVRADAARNRARVLEVAYQTFAA
MLBr_00316|M.leprae_Br4923 ----------MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFAT
MAB_0647|M.abscessus_ATCC_1997 ---------------------MDQPARPLRADAARNRARVLEVAYQTFAE
Mflv_0142|M.gilvum_PYR-GCK ------------------------MTRPLRADAARNRARVLEVAYDTFAA
MMAR_0489|M.marinum_M --------------------MPTVT--WARVDPARRAAIVEAAEAEFGAH
MUL_1152|M.ulcerans_Agy99 --------------------MPTVT--WARVDPARRAAIVEAAEAEFGAH
MAV_2463|M.avium_104 --------------------MTAVEDRPLRSDAARNVERILRAAREVYAE
TH_2712|M.thermoresistible__bu VSLMSADELLPARPATDVAAPTATTAPPEREDAARNRALLLDAARRLIAE
* *.:*. : . *
MSMEG_3807|M.smegmatis_MC2_155 RGLAAS-VADIARRAGVAKGTVFRHFPTKEDLIAAIVTAHTATLSETARS
Mvan_1492|M.vanbaalenii_PYR-1 RGPSAS-VADIARRAGVAKGTVFRHFPTKEDLIAAIVSEHIAVLAAAARR
Mb0068c|M.bovis_AF2122/97 DGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHA
Rv0067c|M.tuberculosis_H37Rv DGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHA
MLBr_00316|M.leprae_Br4923 EGLSVP-IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYV
MAB_0647|M.abscessus_ATCC_1997 EGLGVP-IDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDRMGSVIDKGRE
Mflv_0142|M.gilvum_PYR-GCK EGLTVP-IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAERART
MMAR_0489|M.marinum_M GFSQGS-LNVIARRARVAKGSLFQYFADKRDLYAYIADIASQRVRTHIEG
MUL_1152|M.ulcerans_Agy99 GFSQGS-LNVIARRARVAKGSLFQYFADKRDLYAYIADIANQRVRTHIEG
MAV_2463|M.avium_104 LGPDAP-VEAVARRAGVGERTLYRRFPAKADLVRAALDQS------IAED
TH_2712|M.thermoresistible__bu RGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDETAFQQAFMF
: :* * *. :::: * : *
MSMEG_3807|M.smegmatis_MC2_155 LVDAPDPGAALLEFLTEAADQRRQ------HDLTFLQAASADD------S
Mvan_1492|M.vanbaalenii_PYR-1 LADSPDPGAALLEFLTIAADQRQR------HDLTFLQSASDGD------P
Mb0068c|M.bovis_AF2122/97 LLKSKHPGDALFAFLRSMVLQWGA------TDRGLVEALAGVG--IEISS
Rv0067c|M.tuberculosis_H37Rv LLKSKHPGDALFAFLRSMVLQWGA------TDRGLVEALAGVG--IEISS
MLBr_00316|M.leprae_Br4923 LLKSAGPGEALFTYLRSLVLHWGA------TDRGLVDALAGAGG-IDILG
MAB_0647|M.abscessus_ATCC_1997 LLAAVDPGEALFEFLRS-MMDWGG------TDQGLVDALSGAG--IDVQA
Mflv_0142|M.gilvum_PYR-GCK LLAVEGPGQALFVFFRD-MVRSAA------VDHGLVDALMNQG--LDLEA
MMAR_0489|M.marinum_M LIRELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARIS
MUL_1152|M.ulcerans_Agy99 LIRELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARIS
MAV_2463|M.avium_104 LTPVIDSARHAKDPLHGLTRLVEAAISLGAREQNLLAAAHRAGSLTSDIS
TH_2712|M.thermoresistible__bu GPPPLGPGAEPLERLLAYGRRRLQFVC---DHHALLTDVSREP-----QT
.. : . :
MSMEG_3807|M.smegmatis_MC2_155 SVTAARDELHGYVEQLVAAAREAGAIRADVTGTDVFLLMCTPIH-VVENL
Mvan_1492|M.vanbaalenii_PYR-1 RVTEVRDALHANLETLVDRARTSGAIRADITEADVFLMMCAPIH-IVENL
Mb0068c|M.bovis_AF2122/97 AAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG-----CQAM
Rv0067c|M.tuberculosis_H37Rv AAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG-----CQAM
MLBr_00316|M.leprae_Br4923 VAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVG-----CQAM
MAB_0647|M.abscessus_ATCC_1997 LIPHIEESFYAVLGDLLRAAQQAGTVRSDVGVHEVKALLVG-----CQAM
Mflv_0142|M.gilvum_PYR-GCK VAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVV-----CKVP
MMAR_0489|M.marinum_M VRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLMIFPHLALAP
MUL_1152|M.ulcerans_Agy99 VRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLMIFPHLALAP
MAV_2463|M.avium_104 VS------LNEALGELVREGQRAGRIRADLVADDLPRLVAMLYS--VLST
TH_2712|M.thermoresistible__bu RFGPPMTLHHTHIRSLLAAADADGDL--DVQADALLALTDP---DYVRHQ
: *: . * * : :
MSMEG_3807|M.smegmatis_MC2_155 PDPSPDLWQRYLGILFDGLRPEGAHPLPQPPPRLT-----------
Mvan_1492|M.vanbaalenii_PYR-1 PAPAPLLWQRYLAIIFDGLRPDGAHPLPQPAPAAP-----------
Mb0068c|M.bovis_AF2122/97 QSYNAELAAKVTDVALDGLRANRK----------------------
Rv0067c|M.tuberculosis_H37Rv QSYNAELAAKVTDVALDGLRANRK----------------------
MLBr_00316|M.leprae_Br4923 EAYNSALAERVTDVVVDGLRAAR-----------------------
MAB_0647|M.abscessus_ATCC_1997 QSYNKDVSRQVTDVVFDGLRPRP-----------------------
Mflv_0142|M.gilvum_PYR-GCK QVFDSEVTERVTRVIEDGLRPLR-----------------------
MMAR_0489|M.marinum_M YMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSPSLTVEVRKVT
MUL_1152|M.ulcerans_Agy99 YMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSPSLTVEVRKVT
MAV_2463|M.avium_104 MDAGSEGWRRYVALVVDAISVDERRPLPPAAALRYASQPNSWPL--
TH_2712|M.thermoresistible__bu VTDRGVALDALADSWGDVARKLCRR---------------------
: