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LRQERTGRWRKGMQTRERLLGAALAEFKRNGIAAADTAAIVAAAGVAHGTFFFHFPTKEHVLIELEAREQ ERMVTELTRLYTRPHSVRDTLAETVRLLEKLERRLGRRLFKDFLALHFSTTRPPSQEWTRYPALTVIISE LQRAQQRGEIPADVDVMHVGVSFVVGLYALLITIPEARDARAPVLEVYLTTYLYGLRVLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6527 | - | - | 100% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 5e-51 | 53.12% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 3e-07 | 31.21% (141) | TetR-type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 2e-05 | 33.33% (66) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1253 | - | 4e-77 | 70.05% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 2e-05 | 33.33% (66) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1379c | - | 3e-08 | 29.00% (200) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 2e-39 | 44.02% (184) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2459 | - | 3e-49 | 52.60% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1791 | - | 1e-81 | 72.36% (199) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 8e-37 | 41.85% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | 4e-49 | 52.08% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3605|M.bovis_AF2122/97 -------MAVLAESELGSEAQR-ERRKRILDATMAIASKGGYEAVQMRAV
Rv3574|M.tuberculosis_H37Rv -------MAVLAESELGSEAQR-ERRKRILDATMAIASKGGYEAVQMRAV
Mflv_1253|M.gilvum_PYR-GCK ---------MLKSRTPERGRKGEQTRERLLGAAIAEFKRDGMAAADIGAI
TH_1791|M.thermoresistible__bu ---------VLNERTSDRGSKGRQTRERLLGAAIAEFKRGGMAAADVASI
MSMEG_6527|M.smegmatis_MC2_155 ---------MLRQERTGRWRKGMQTRERLLGAALAEFKRNGIAAADTAAI
MAV_2459|M.avium_104 ----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
Mvan_1513|M.vanbaalenii_PYR-1 ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAI
MMAR_0249|M.marinum_M MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99 MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MAB_1379c|M.abscessus_ATCC_199 ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
: . * .::.*::* . * :
Mb3605|M.bovis_AF2122/97 ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAG------
Rv3574|M.tuberculosis_H37Rv ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAG------
Mflv_1253|M.gilvum_PYR-GCK VSAAGVAHGTFFFHFPTKEHVLVELENREQERMAAELTRFYRRP------
TH_1791|M.thermoresistible__bu VAAAGVAHGTFFFHFPTKEHVLVELERREEERMAAELNRYFRTP------
MSMEG_6527|M.smegmatis_MC2_155 VAAAGVAHGTFFFHFPTKEHVLIELEAREQERMVTELTRLYTRP------
MAV_2459|M.avium_104 VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLKSE------
Mvan_1513|M.vanbaalenii_PYR-1 VAAAGVAHGTFFFHFPTKEHVLLELERREEDRMAKRFATFTKTH------
MMAR_0249|M.marinum_M AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADP------
MUL_4864|M.ulcerans_Agy99 AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADS------
MAB_1379c|M.abscessus_ATCC_199 VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLAE
. ..:* **:: :* :* .:: . :
Mb3605|M.bovis_AF2122/97 -ATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKL
Rv3574|M.tuberculosis_H37Rv -ATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKL
Mflv_1253|M.gilvum_PYR-GCK -HDVRATLTKAVTVLEALERRLGSRLFKDFLALHFSTRRPPSEEWSAHPV
TH_1791|M.thermoresistible__bu -HTVRQTLAEIVRLLEDLERRLGTRLFKDFLALHFSTTRPPSEEWSRHPV
MSMEG_6527|M.smegmatis_MC2_155 -HSVRDTLAETVRLLEKLERRLGRRLFKDFLALHFSTTRPPSQEWTRYPA
MAV_2459|M.avium_104 -HDLASALNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHPL
Mvan_1513|M.vanbaalenii_PYR-1 -HDLASALREAAHLVMGLERRLGVVLFKDFLALHFSPTRPPAEHGDDHPL
MMAR_0249|M.marinum_M -TDLVSVLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPL
MUL_4864|M.ulcerans_Agy99 -TDLVSVLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPL
MAB_1379c|M.abscessus_ATCC_199 YRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAA
: : : .
Mb3605|M.bovis_AF2122/97 IDSMFARAMANG---EPTEDQYHIARVISDVWLSN-LLAWLTRRASATDV
Rv3574|M.tuberculosis_H37Rv IDSMFARAMANG---EPTEDQYHIARVISDVWLSN-LLAWLTRRASATDV
Mflv_1253|M.gilvum_PYR-GCK IVAVVEDLERAR---DRGEIPADVDVMLRGVSFLVGLYALLITMPESREI
TH_1791|M.thermoresistible__bu IAAVVEELQRAR---DRGEIPEDVDVMHNGVSFLTGLYALLITMPESHDL
MSMEG_6527|M.smegmatis_MC2_155 LTVIISELQRAQ---QRGEIPADVDVMHVGVSFVVGLYALLITIPEARDA
MAV_2459|M.avium_104 IVLVANEIEGAQ---QRGETDPHVNPMNSAVFFLLGLYALLITTNHWPTG
Mvan_1513|M.vanbaalenii_PYR-1 VVLVADQIDNAR---QRGDTAADVTPMNSAIYFLLGLYALLITTDDSTGR
MMAR_0249|M.marinum_M AEFVIETIARAQ---RANRVPPDADAGELGVIFLTGLFALLATGATTPDA
MUL_4864|M.ulcerans_Agy99 AEFVIETIAQAQ---RADRVAPDADAGELGVIFLTGLFALLATGATTPDA
MAB_1379c|M.abscessus_ATCC_199 IQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFEQ
. : : : :
Mb3605|M.bovis_AF2122/97 SK-RLDLAVRLLIGDQDSA--------
Rv3574|M.tuberculosis_H37Rv SK-RLDLAVRLLIGDQDSA--------
Mflv_1253|M.gilvum_PYR-GCK RAPVIDEYVTTYMDALHAA--------
TH_1791|M.thermoresistible__bu RAPALSEYLTTYVHGMRVRSDPPAIAR
MSMEG_6527|M.smegmatis_MC2_155 RAPVLEVYLTTYLYGLRVLP-------
MAV_2459|M.avium_104 HA-LLEDYVARTLRSLKP---------
Mvan_1513|M.vanbaalenii_PYR-1 RE-LVDDYLTRTLRSLQ----------
MMAR_0249|M.marinum_M RTALLNRFVTTVVHGMEAR--------
MUL_4864|M.ulcerans_Agy99 RTALLNGFVTTVVHGMEAR--------
MAB_1379c|M.abscessus_ATCC_199 LAHAVREILYYGLASDHHPQIAD----
: : :