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LPRHEPASRHGRPLRRDAAENRERVLAAAVALFAREGRDVSMATIADEAGVGVGTLYRRYPTREMLLQAL TERSFELVLGAIERVQRECGPAICKLEMFYDATIAHRQELVLPLHGGPQNLSDAAKFTRNRIRDIAEEIL EDGRSDRTIRADVTAADVIGFGALLAHTLSSDPQWVAVLHRQKQIYLAGLAPSAPALEELPT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3354 | - | - | 100% (202) | TetR family protein transcriptional regulatory protein |
M. smegmatis MC2 155 | MSMEG_3452 | - | 3e-17 | 35.22% (159) | TetR family protein transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_1380 | - | 9e-16 | 34.55% (165) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0068c | - | 5e-13 | 32.70% (159) | TetR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_0142 | - | 1e-12 | 34.23% (149) | TetR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0067c | - | 5e-13 | 32.70% (159) | TetR family transcriptional regulator |
M. leprae Br4923 | MLBr_00316 | - | 3e-12 | 54.24% (59) | putative TetR/AcrR-family transcriptional regulator |
M. abscessus ATCC 19977 | MAB_4384 | - | 4e-16 | 32.52% (163) | TetR family transcriptional regulator |
M. marinum M | MMAR_1637 | - | 3e-08 | 36.84% (114) | TetR family transcriptional regulator |
M. avium 104 | MAV_4593 | - | 3e-17 | 36.73% (147) | TetR family protein transcriptional regulator |
M. thermoresistible (build 8) | TH_2712 | - | 3e-07 | 28.30% (212) | PUTATIVE transcriptional regulator, TetR family |
M. ulcerans Agy99 | MUL_3399 | - | 2e-08 | 36.84% (114) | TetR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_1059 | - | 2e-16 | 35.98% (164) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRARVLE Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRARVLE MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRARVLE MAB_4384|M.abscessus_ATCC_1997 --------------------------MNGREVAHRPLRKDAERNRKRVIA Mvan_1059|M.vanbaalenii_PYR-1 --------------------------MIDK--PCRGLRKDAERNRQRVLT MAV_4593|M.avium_104 ----------------------------------MVGRSDARRNRQRLLE MMAR_1637|M.marinum_M --------------------MSGVEGLGELPVSARQERGDAARNRELLLQ MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ TH_2712|M.thermoresistible__bu ----VSLMSADELLP----ARPATDVAAPTATTAPPEREDAARNRALLLD MSMEG_3354|M.smegmatis_MC2_155 -----------------------MPRHEPASRHGRPLRRDAAENRERVLA * ** .** :: Mb0068c|M.bovis_AF2122/97 VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH Rv0067c|M.tuberculosis_H37Rv VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH MLBr_00316|M.leprae_Br4923 VAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP Mflv_0142|M.gilvum_PYR-GCK VAYDTFAAEG-LTVPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR MAB_4384|M.abscessus_ATCC_1997 AARELFAVHG-LESTLNEVAHHAGLGVGTVYRRFPTKEALFEAIYVDGMD Mvan_1059|M.vanbaalenii_PYR-1 AARELFAVEG-MEASLNDVARHAGVGVGTVYRRFATKEELVEAIFESGVD MAV_4593|M.avium_104 AATAAFTAHG-ASVSLESIARDAGVGIGTLYRHFPNREALVEAVYRAELA MMAR_1637|M.marinum_M AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER MUL_3399|M.ulcerans_Agy99 AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER TH_2712|M.thermoresistible__bu AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET MSMEG_3354|M.smegmatis_MC2_155 AAVALFAREG-RDVSMATIADEAGVGVGTLYRRYPTREMLLQALTERSFE .* .: * . :* **:* **::*:: .: * : Mb0068c|M.bovis_AF2122/97 RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS Rv0067c|M.tuberculosis_H37Rv RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS MLBr_00316|M.leprae_Br4923 HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDIL Mflv_0142|M.gilvum_PYR-GCK RIAERARTLLAVEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG-LDLE MAB_4384|M.abscessus_ATCC_1997 QLSGLAEAALRHENSWEG-FEWFVHQMCEITATNRGLREIAFSKA--HGG Mvan_1059|M.vanbaalenii_PYR-1 EVVCLAEAALRHQDSWEG-FVWFVERQCLLTATDRGLREMVYSKA--YGG MAV_4593|M.avium_104 EVAAAAAQLLQR-HPPKAALRRWMDRYATFVATKRGMAESLQAIF-ESGA MMAR_1637|M.marinum_M ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL MUL_3399|M.ulcerans_Agy99 ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL TH_2712|M.thermoresistible__bu AFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALLTDVS-REPQ MSMEG_3354|M.smegmatis_MC2_155 LVLGAIERVQRECGPAICKLEMFYD---ATIAHRQELVLPLHGGP-QNLS . : Mb0068c|M.bovis_AF2122/97 SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN Rv0067c|M.tuberculosis_H37Rv SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN MLBr_00316|M.leprae_Br4923 GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN Mflv_0142|M.gilvum_PYR-GCK AVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFD MAB_4384|M.abscessus_ATCC_1997 DHVEAGRARLLPLLSKVVERAQEDGYLRPEASATDMPFFGVLTGAVSEFA Mvan_1059|M.vanbaalenii_PYR-1 NRVERVRERLAPLMKELVERARRDGYLRPDVESTDMPVIGLLAGTVGEWA MAV_4593|M.avium_104 LVPSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIGIFLVSGSP MMAR_1637|M.marinum_M TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR MUL_3399|M.ulcerans_Agy99 TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR TH_2712|M.thermoresistible__bu TRFGPPMTLHHTHIRSLLAAADADGDLDVQADALLALTDPDYVRHQVTDR MSMEG_3354|M.smegmatis_MC2_155 DAAKFTRNRIRDIAEEILEDGRSDRTIRADVTAADVIGFGALLAHTLSSD :: . :. Mb0068c|M.bovis_AF2122/97 ----AELAAKVTDVALDGLRANRK-------------------------- Rv0067c|M.tuberculosis_H37Rv ----AELAAKVTDVALDGLRANRK-------------------------- MLBr_00316|M.leprae_Br4923 ----SALAERVTDVVVDGLRAAR--------------------------- Mflv_0142|M.gilvum_PYR-GCK ----SEVTERVTRVIEDGLRPLR--------------------------- MAB_4384|M.abscessus_ATCC_1997 GEVNADLWRRYMAILIEGMRRRDDQERLEVDALDEAQIDAAMTTWQPAGS Mvan_1059|M.vanbaalenii_PYR-1 GDVDPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAMHGWDPSG- MAV_4593|M.avium_104 -----EQTGRMLDLLVAGVTR----------------------------- MMAR_1637|M.marinum_M GHTLRTLGDAWEDLARKLCGR----------------------------- MUL_3399|M.ulcerans_Agy99 GHTLRTLGDAWEDLARKLCGR----------------------------- TH_2712|M.thermoresistible__bu GVALDALADSWGDVARKLCRR----------------------------- MSMEG_3354|M.smegmatis_MC2_155 PQWVAVLHRQKQIYLAGLAPSAPALEELPT-------------------- Mb0068c|M.bovis_AF2122/97 - Rv0067c|M.tuberculosis_H37Rv - MLBr_00316|M.leprae_Br4923 - Mflv_0142|M.gilvum_PYR-GCK - MAB_4384|M.abscessus_ATCC_1997 G Mvan_1059|M.vanbaalenii_PYR-1 - MAV_4593|M.avium_104 - MMAR_1637|M.marinum_M - MUL_3399|M.ulcerans_Agy99 - TH_2712|M.thermoresistible__bu - MSMEG_3354|M.smegmatis_MC2_155 -