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M. smegmatis MC2 155 MSMEG_3354 (-)

annotation: TetR family protein transcriptional regulatory protein
coordinates: 3429446 - 3430054
length: 202

LPRHEPASRHGRPLRRDAAENRERVLAAAVALFAREGRDVSMATIADEAGVGVGTLYRRYPTREMLLQAL
TERSFELVLGAIERVQRECGPAICKLEMFYDATIAHRQELVLPLHGGPQNLSDAAKFTRNRIRDIAEEIL
EDGRSDRTIRADVTAADVIGFGALLAHTLSSDPQWVAVLHRQKQIYLAGLAPSAPALEELPT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3354--100% (202)TetR family protein transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_3452-3e-1735.22% (159) TetR family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_1380-9e-1634.55% (165) transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0068c-5e-1332.70% (159) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0142-1e-1234.23% (149) TetR family transcriptional regulator
M. tuberculosis H37RvRv0067c-5e-1332.70% (159) TetR family transcriptional regulator
M. leprae Br4923MLBr_00316-3e-1254.24% (59) putative TetR/AcrR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4384-4e-1632.52% (163) TetR family transcriptional regulator
M. marinum MMMAR_1637-3e-0836.84% (114) TetR family transcriptional regulator
M. avium 104MAV_4593-3e-1736.73% (147) TetR family protein transcriptional regulator
M. thermoresistible (build 8)TH_2712-3e-0728.30% (212) PUTATIVE transcriptional regulator, TetR family
M. ulcerans Agy99MUL_3399-2e-0836.84% (114) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1059-2e-1635.98% (164) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0068c|M.bovis_AF2122/97           -----------------------------MAPTDRRVRADAARNRARVLE
Rv0067c|M.tuberculosis_H37Rv        -----------------------------MAPTDRRVRADAARNRARVLE
MLBr_00316|M.leprae_Br4923          ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
Mflv_0142|M.gilvum_PYR-GCK          --------------------------------MTRPLRADAARNRARVLE
MAB_4384|M.abscessus_ATCC_1997      --------------------------MNGREVAHRPLRKDAERNRKRVIA
Mvan_1059|M.vanbaalenii_PYR-1       --------------------------MIDK--PCRGLRKDAERNRQRVLT
MAV_4593|M.avium_104                ----------------------------------MVGRSDARRNRQRLLE
MMAR_1637|M.marinum_M               --------------------MSGVEGLGELPVSARQERGDAARNRELLLQ
MUL_3399|M.ulcerans_Agy99           MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ
TH_2712|M.thermoresistible__bu      ----VSLMSADELLP----ARPATDVAAPTATTAPPEREDAARNRALLLD
MSMEG_3354|M.smegmatis_MC2_155      -----------------------MPRHEPASRHGRPLRRDAAENRERVLA
                                                                         * ** .**  :: 

Mb0068c|M.bovis_AF2122/97           VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
Rv0067c|M.tuberculosis_H37Rv        VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
MLBr_00316|M.leprae_Br4923          VAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
Mflv_0142|M.gilvum_PYR-GCK          VAYDTFAAEG-LTVPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR
MAB_4384|M.abscessus_ATCC_1997      AARELFAVHG-LESTLNEVAHHAGLGVGTVYRRFPTKEALFEAIYVDGMD
Mvan_1059|M.vanbaalenii_PYR-1       AARELFAVEG-MEASLNDVARHAGVGVGTVYRRFATKEELVEAIFESGVD
MAV_4593|M.avium_104                AATAAFTAHG-ASVSLESIARDAGVGIGTLYRHFPNREALVEAVYRAELA
MMAR_1637|M.marinum_M               AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
MUL_3399|M.ulcerans_Agy99           AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
TH_2712|M.thermoresistible__bu      AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET
MSMEG_3354|M.smegmatis_MC2_155      AAVALFAREG-RDVSMATIADEAGVGVGTLYRRYPTREMLLQALTERSFE
                                    .*   .:  *    .   :*  **:* **::*:: .:  *   :      

Mb0068c|M.bovis_AF2122/97           RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
Rv0067c|M.tuberculosis_H37Rv        RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
MLBr_00316|M.leprae_Br4923          HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDIL
Mflv_0142|M.gilvum_PYR-GCK          RIAERARTLLAVEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG-LDLE
MAB_4384|M.abscessus_ATCC_1997      QLSGLAEAALRHENSWEG-FEWFVHQMCEITATNRGLREIAFSKA--HGG
Mvan_1059|M.vanbaalenii_PYR-1       EVVCLAEAALRHQDSWEG-FVWFVERQCLLTATDRGLREMVYSKA--YGG
MAV_4593|M.avium_104                EVAAAAAQLLQR-HPPKAALRRWMDRYATFVATKRGMAESLQAIF-ESGA
MMAR_1637|M.marinum_M               ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
MUL_3399|M.ulcerans_Agy99           ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
TH_2712|M.thermoresistible__bu      AFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALLTDVS-REPQ
MSMEG_3354|M.smegmatis_MC2_155      LVLGAIERVQRECGPAICKLEMFYD---ATIAHRQELVLPLHGGP-QNLS
                                                  .    :                              

Mb0068c|M.bovis_AF2122/97           SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
Rv0067c|M.tuberculosis_H37Rv        SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
MLBr_00316|M.leprae_Br4923          GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN
Mflv_0142|M.gilvum_PYR-GCK          AVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFD
MAB_4384|M.abscessus_ATCC_1997      DHVEAGRARLLPLLSKVVERAQEDGYLRPEASATDMPFFGVLTGAVSEFA
Mvan_1059|M.vanbaalenii_PYR-1       NRVERVRERLAPLMKELVERARRDGYLRPDVESTDMPVIGLLAGTVGEWA
MAV_4593|M.avium_104                LVPSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIGIFLVSGSP
MMAR_1637|M.marinum_M               TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR
MUL_3399|M.ulcerans_Agy99           TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR
TH_2712|M.thermoresistible__bu      TRFGPPMTLHHTHIRSLLAAADADGDLDVQADALLALTDPDYVRHQVTDR
MSMEG_3354|M.smegmatis_MC2_155      DAAKFTRNRIRDIAEEILEDGRSDRTIRADVTAADVIGFGALLAHTLSSD
                                                    ::  .        :.                   

Mb0068c|M.bovis_AF2122/97           ----AELAAKVTDVALDGLRANRK--------------------------
Rv0067c|M.tuberculosis_H37Rv        ----AELAAKVTDVALDGLRANRK--------------------------
MLBr_00316|M.leprae_Br4923          ----SALAERVTDVVVDGLRAAR---------------------------
Mflv_0142|M.gilvum_PYR-GCK          ----SEVTERVTRVIEDGLRPLR---------------------------
MAB_4384|M.abscessus_ATCC_1997      GEVNADLWRRYMAILIEGMRRRDDQERLEVDALDEAQIDAAMTTWQPAGS
Mvan_1059|M.vanbaalenii_PYR-1       GDVDPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAMHGWDPSG-
MAV_4593|M.avium_104                -----EQTGRMLDLLVAGVTR-----------------------------
MMAR_1637|M.marinum_M               GHTLRTLGDAWEDLARKLCGR-----------------------------
MUL_3399|M.ulcerans_Agy99           GHTLRTLGDAWEDLARKLCGR-----------------------------
TH_2712|M.thermoresistible__bu      GVALDALADSWGDVARKLCRR-----------------------------
MSMEG_3354|M.smegmatis_MC2_155      PQWVAVLHRQKQIYLAGLAPSAPALEELPT--------------------
                                                                                      

Mb0068c|M.bovis_AF2122/97           -
Rv0067c|M.tuberculosis_H37Rv        -
MLBr_00316|M.leprae_Br4923          -
Mflv_0142|M.gilvum_PYR-GCK          -
MAB_4384|M.abscessus_ATCC_1997      G
Mvan_1059|M.vanbaalenii_PYR-1       -
MAV_4593|M.avium_104                -
MMAR_1637|M.marinum_M               -
MUL_3399|M.ulcerans_Agy99           -
TH_2712|M.thermoresistible__bu      -
MSMEG_3354|M.smegmatis_MC2_155      -