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MSVPTLPTGPTVDLAQAAERLIKGRRAVRAFRPDEVPEETMRAVFELAGHAPSNSNTQPWHVEVVSGAAR DRLAEALVTAHAEERVTVDFPYREGLFQGVLQERRADFGSRLYAALGIARDQTDLLQGYNTESLRFYGAP HVAMLFAPNNTEARIAGDMGIYAQTLMLAMTAHGIASCPQALLSFYADTVRAELGVENRKLLMGISFGYA DDTAAVNGVRIPRAGLSETTRFSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6505 | - | - | 100% (234) | NfnB protein |
| M. smegmatis MC2 155 | MSMEG_2354 | - | 5e-28 | 35.43% (223) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3462 | - | 7e-26 | 36.11% (216) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3290 | fbiB | 5e-06 | 26.48% (219) | F420-0--gamma-glutamyl ligase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3262 | fbiB | 6e-06 | 26.48% (219) | F420-0--gamma-glutamyl ligase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2661c | - | 2e-24 | 33.63% (223) | putative nitroreductase |
| M. marinum M | MMAR_1739 | - | 2e-28 | 33.95% (215) | nitroreductase |
| M. avium 104 | MAV_1962 | - | 1e-06 | 29.71% (175) | NADPH nitroreductase |
| M. thermoresistible (build 8) | TH_0777 | - | 2e-05 | 27.23% (213) | PROBABLE F420 BIOSYNTHESIS PROTEIN FBIB |
| M. ulcerans Agy99 | MUL_1982 | - | 9e-14 | 31.01% (129) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1213 | - | 2e-25 | 34.70% (219) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6505|M.smegmatis_MC2_155 --------------------------------------------------
Mb3290|M.bovis_AF2122/97 --------MTGP-EHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLR
Rv3262|M.tuberculosis_H37Rv --------MTGP-EHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLR
TH_0777|M.thermoresistible__bu VSTAGGAGQTGSGDHGTAAAIELFPVTGLPQFCPGDDLTAAVAAAAPWLR
MAV_1962|M.avium_104 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6505|M.smegmatis_MC2_155 --------------------------------------------------
Mb3290|M.bovis_AF2122/97 DGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDR
Rv3262|M.tuberculosis_H37Rv DGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDR
TH_0777|M.thermoresistible__bu DNDVVVVTSKVVSKCEGRIIAAPADPEQRDALRRKLIDEEAVRVLARKGR
MAV_1962|M.avium_104 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6505|M.smegmatis_MC2_155 --------------------------------------------------
Mb3290|M.bovis_AF2122/97 TLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLG
Rv3262|M.tuberculosis_H37Rv TLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLG
TH_0777|M.thermoresistible__bu TLITENALGLVQAAAGVDGSNVAATELALLPVDPDASAAALRAGLRQRLG
MAV_1962|M.avium_104 --------------------------------------------------
MMAR_1739|M.marinum_M -------------------------------------------------M
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6505|M.smegmatis_MC2_155 -----------------------------------MSVPTLPTGPTVDLA
Mb3290|M.bovis_AF2122/97 VTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTE
Rv3262|M.tuberculosis_H37Rv VTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTE
TH_0777|M.thermoresistible__bu VDVGVIITDTMGRAWRTGQTDFAIGAAGLTVLHGYAGSHDRHGNELFVTE
MAV_1962|M.avium_104 -------------------------------------------------M
MMAR_1739|M.marinum_M YDLDETIRLRRSTRMFLPR-PVPRRLVQEALELAMCAPSNSNVQP-----
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 MDVYDAVASRRSVREFVDR-PVSPATLTRVLTAAARAPSGGNLQP-----
Mvan_1213|M.vanbaalenii_PYR-1 MDVYEAVRSRRAVRGFTDE-PVPQAVLERVLAAAAWAPSGSNLQP-----
MSMEG_6505|M.smegmatis_MC2_155 QAAERLIKGRRAVRAFRPD-EVPEETMRAVFELAGHAPSNSNTQP-----
Mb3290|M.bovis_AF2122/97 VAVADEIAAAADLVKGKLT-ATPVAVVRGFGVSDDGSTARQLLRPGANDL
Rv3262|M.tuberculosis_H37Rv VAVADEIAAAADLVKGKLT-ATPVAVVRGFGVSDDGSTARQLLRPGANDL
TH_0777|M.thermoresistible__bu VAVADEIAAAADLVKGKLT-DVPVAVVRGLTLRDDGSTARTLVRPGQDDL
MAV_1962|M.avium_104 SDLRAVMQAQRACRRFDPDGKVLDSDIEQMLQLAAHAPSAENTQP-----
MMAR_1739|M.marinum_M -WH---VVFTSGAARDRLVAAMLERARSEPPNVAR--------LPPAFTH
MUL_1982|M.ulcerans_Agy99 -------------------------------------------MPPAFTH
MAB_2661c|M.abscessus_ATCC_199 -WH---VYVLSGARLAELKERIARRVIAGDRGDALEVAMYPQPLDSPYRE
Mvan_1213|M.vanbaalenii_PYR-1 -WH---IYVVTGAPLAQMKKLATERVAAGDPWDEREYVMYPPVLKSPYHE
MSMEG_6505|M.smegmatis_MC2_155 -WH---VEVVSGAARDRLAEALVT--AHAEERVTVDFPYREGLFQGVLQE
Mb3290|M.bovis_AF2122/97 FWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPH
Rv3262|M.tuberculosis_H37Rv FWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPH
TH_0777|M.thermoresistible__bu FWLGTEEAIRLGRSQAQLLRRSVRRFDSEPVPADLIEAAVAEALTAPAPH
MAV_1962|M.avium_104 -WS--FVVVRAEENRKLLADWWTETWNAGG--------------------
MMAR_1739|M.marinum_M LR------------------SALGAQVYGAMGIARDDTQARQTAVLRNWE
MUL_1982|M.ulcerans_Agy99 LR------------------SALGAQVYGAMGIARDDTQARQTAVLRNWE
MAB_2661c|M.abscessus_ATCC_199 RL------------------YDFGHRRYGALGIDHDDHDARAAVRAGNWA
Mvan_1213|M.vanbaalenii_PYR-1 RR------------------ATFGRERYSALGIEREDWEARQRAAIANWD
MSMEG_6505|M.smegmatis_MC2_155 RR------------------ADFGSRLYAALGIARDQTDLLQGYNTESLR
Mb3290|M.bovis_AF2122/97 HTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQI
Rv3262|M.tuberculosis_H37Rv HTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQI
TH_0777|M.thermoresistible__bu HTRPVRFVWLQNWTARTRLLDRMKDRWRADLAGDGASPEAVERRVGRGQI
MAV_1962|M.avium_104 -----------------------GDFVRQNLEDKALVADLEFGFNKGG--
: : .
MMAR_1739|M.marinum_M FFRAPLGGIVSMHQELGLVD-------------SMGVGMFLQNLMLALTA
MUL_1982|M.ulcerans_Agy99 FFRAPLGGIVSMHQELGLVD-------------SMGVGMFLQNLMLALTA
MAB_2661c|M.abscessus_ATCC_199 CFGASTALFCYLDRDMPPPQ-------------WGDAGMYLQTIMLLLRA
Mvan_1213|M.vanbaalenii_PYR-1 CFGAPAALFCYIDRDLGRPQ-------------WSDLGMYLQTVMLLLRA
MSMEG_6505|M.smegmatis_MC2_155 FYGAPHVAMLFAPNNTEARI-------------AGDMGIYAQTLMLAMTA
Mb3290|M.bovis_AF2122/97 LYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAV
Rv3262|M.tuberculosis_H37Rv LYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAV
TH_0777|M.thermoresistible__bu LYDAPELIVPFLVADGAHHYPDARRAAAEHTMFTVAGGAAVQALLVALAV
MAV_1962|M.avium_104 FAAAPVVVVVCADTDRVAEIY-----------APSSIYPAVQNLLLAAAD
*. . : * :::
MMAR_1739|M.marinum_M RGLGTCVQVSIAGY-PEIVRKQVGIPSHLTILCGLAIGYPDPDFAGNQLR
MUL_1982|M.ulcerans_Agy99 RGLGTCVQVSIAGY-PEIVRKQVGIPSHLTILCGLAIGYPDPDFAGNQLR
MAB_2661c|M.abscessus_ATCC_199 EGLDSCPQIAWAEY-HRTVAEVIAPPPQRVLYCGMSIGYRNPETK--APE
Mvan_1213|M.vanbaalenii_PYR-1 EGLHSCPQMAWSQV-RSTVAQVLSPPDELMLFCGMSIGHEDTSVG--YVP
MSMEG_6505|M.smegmatis_MC2_155 HGIASCPQALLSFY-ADTVRAELG-VENRKLLMGISFGYADDTAAVNGVR
Mb3290|M.bovis_AF2122/97 RGLGSCWIGSTIFA-ADLVRDELDLPVDWEPLGAIAIGYADEPSG-----
Rv3262|M.tuberculosis_H37Rv RGLGSCWIGSTIFA-ADLVRDELDLPVDWEPLGAIAIGYADEPSG-----
TH_0777|M.thermoresistible__bu REIGSCWVGSTIFA-PEVVRTELGLPDDWEPLGAVAIGYPAEPAG-----
MAV_1962|M.avium_104 LGYGSCLTTGLTTFGVDRVRELLELPPNLIPMAAVYVGRPVKKLS-PPRR
:* * : . .: .*
MMAR_1739|M.marinum_M VGRDDVAEHVVFLDD-
MUL_1982|M.ulcerans_Agy99 VGRDDVAEHVVFLDD-
MAB_2661c|M.abscessus_ATCC_199 MPRAALSETVTFL---
Mvan_1213|M.vanbaalenii_PYR-1 TGRSALAETVTFVNG-
MSMEG_6505|M.smegmatis_MC2_155 IPRAGLSETTRFSR--
Mb3290|M.bovis_AF2122/97 -LRDPVPAADLLILK-
Rv3262|M.tuberculosis_H37Rv -LRDPVPAADLLILK-
TH_0777|M.thermoresistible__bu -PRDPAPTEGLLVFR-
MAV_1962|M.avium_104 RPVSEVTYREKFGTAW
. :