For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DVYDAVASRRSVREFVDRPVSPATLTRVLTAAARAPSGGNLQPWHVYVLSGARLAELKERIARRVIAGDR GDALEVAMYPQPLDSPYRERLYDFGHRRYGALGIDHDDHDARAAVRAGNWACFGASTALFCYLDRDMPPP QWGDAGMYLQTIMLLLRAEGLDSCPQIAWAEYHRTVAEVIAPPPQRVLYCGMSIGYRNPETKAPEMPRAA LSETVTFL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2661c | - | - | 100% (219) | putative nitroreductase |
| M. abscessus ATCC 19977 | MAB_3351c | - | 2e-08 | 54.90% (51) | putative nitroreductase |
| M. abscessus ATCC 19977 | MAB_4759 | - | 8e-05 | 35.90% (78) | nitroreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1390c | moeY | 3e-05 | 30.93% (97) | hypothetical protein Mb1390c |
| M. gilvum PYR-GCK | Mflv_1262 | - | 6e-10 | 28.31% (219) | nitroreductase |
| M. tuberculosis H37Rv | Rv1355c | moeY | 3e-05 | 30.93% (97) | hypothetical protein Rv1355c |
| M. leprae Br4923 | MLBr_01751 | - | 1e-05 | 42.86% (49) | hypothetical protein MLBr_01751 |
| M. marinum M | MMAR_1739 | - | 5e-25 | 32.73% (220) | nitroreductase |
| M. avium 104 | MAV_0933 | - | 2e-09 | 28.04% (214) | nitroreductase family protein |
| M. smegmatis MC2 155 | MSMEG_3462 | - | 2e-68 | 56.42% (218) | oxidoreductase |
| M. thermoresistible (build 8) | TH_1618 | - | 6e-09 | 26.20% (229) | nitroreductase family protein |
| M. ulcerans Agy99 | MUL_1982 | - | 1e-13 | 32.54% (126) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1213 | - | 2e-71 | 57.99% (219) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 ----------MTIPHE-GGSTGILVLRDDDHDDVLVLDRLRSDPSIEFVD
Rv1355c|M.tuberculosis_H37Rv ----------MTIPHE-GGSTGILVLRDDDHDDVLVLDRLRSDPSIEFVD
MLBr_01751|M.leprae_Br4923 MAYGCNPRGAARVSDERDVSPYARVLALDDPADAAVLQRLRADSKVDFVD
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 RFAEQLAGVRRLLPQPDPDLLEEAKRWAYYPWRRMVVAILGPRGFRAVRL
Rv1355c|M.tuberculosis_H37Rv RFAEQLAGVRRLLPQPDPDLLEEAKRWAYYPWRRMVVAILGLRGFRAVRL
MLBr_01751|M.leprae_Br4923 HHERQLQELLSLLPTPDPQLIAEPCRWVYYPWRHVVVSMLGPRGFRAVRL
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 DRNRHLITAEEQRALHALRVGVVGLSAGHAIAYTLAAEGACGTLRLADFD
Rv1355c|M.tuberculosis_H37Rv DRNRHLITAEEQRALHALRVGVVGLSAGHAIAYTLAAEGACGTLRLADFD
MLBr_01751|M.leprae_Br4923 DRNRNEITAEEQVALGRLHIGVAGLSVGHVIAHTLAAQGLCGQLRLADFD
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 KIELSNLNRVPVGVFDIGLNKAMIAARRIAELDPYLAVDLVTSGLSPESV
Rv1355c|M.tuberculosis_H37Rv KIELSNLNRVPVGVFDIGLNKAMIAARRIAELDPYLAVDLVTSGLSPESV
MLBr_01751|M.leprae_Br4923 RLELSNLNRVPATVFDLGLNKAEVAARRIAELDPYLTVRVFDNGLTFDTV
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 DEFLDGLDVVIEECDSLDIKVILRQAACARGVPVLMATSDRGLVDVERYD
Rv1355c|M.tuberculosis_H37Rv DEFLDGLDVVIEECDSLDIKVILRQAACARGVPVLMATSDRGLVDVERYD
MLBr_01751|M.leprae_Br4923 DQFLEGLDVVVEQCDSLDIKALLREGARSHGIPVLMATSDRGLIDVERFD
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 VEPGRPIFHGLLGDIDADKLCGLTTKDKVPHVLNILDCQELSARCAASMI
Rv1355c|M.tuberculosis_H37Rv VEPGRPIFHGLLGDIDADKLCGLTTKDKVPHVLNILDCQELSARCAASMI
MLBr_01751|M.leprae_Br4923 LEPRRSILHGLLGELDIRLLPEMSNREKIPYILRFLEAERLSPRTATTLV
MSMEG_3462|M.smegmatis_MC2_155 -----------------------------------MSDVYEAVISRRAVR
Mvan_1213|M.vanbaalenii_PYR-1 ------------------------------------MDVYEAVRSRRAVR
MAB_2661c|M.abscessus_ATCC_199 ------------------------------------MDVYDAVASRRSVR
MMAR_1739|M.marinum_M -----------------------------------MYDLDETIRLRRSTR
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK -----------------------------MDMPHPTDNVWEVLSTARSIR
TH_1618|M.thermoresistible__bu -------------------------------MPHPTNDVWEVLSTARSIR
MAV_0933|M.avium_104 -----------------------------------------MMSTARTIR
Mb1390c|M.bovis_AF2122/97 EVDQTLWGWPQLAGDIWVGAATVAEAVRRIGLGEPLESGRVRVDVSAALD
Rv1355c|M.tuberculosis_H37Rv EVDQTLWGWPQLAGDIWVGAATVAEAVRRIGLGEPLESGRVRVDVSAALD
MLBr_01751|M.leprae_Br4923 EIDRSLSTWPQLAGDVALGATAVAEAVRRIGLGEELRSGRARIDVASALN
MSMEG_3462|M.smegmatis_MC2_155 GFTDRPVP-------------------KAVLARVLSAAAWSPSSSNTQPW
Mvan_1213|M.vanbaalenii_PYR-1 GFTDEPVP-------------------QAVLERVLAAAAWAPSGSNLQPW
MAB_2661c|M.abscessus_ATCC_199 EFVDRPVS-------------------PATLTRVLTAAARAPSGGNLQPW
MMAR_1739|M.marinum_M MFLPRPVP-------------------RRLVQEALELAMCAPSNSNVQPW
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK RFTDEPVD-------------------SATLDRCLQAATWAPNGANAQLW
TH_1618|M.thermoresistible__bu RFTDEPVD-------------------DATLQRCLQAATWAPNGANAQLW
MAV_0933|M.avium_104 RFTDEPVD-------------------DATLARCLGAARWAPSGANAQGW
Mb1390c|M.bovis_AF2122/97 RLDQPPMPSRGNGWLLESVPPTAPAEPQPTSEIVAQAAIRAPSGGNVQPW
Rv1355c|M.tuberculosis_H37Rv RLDQPPMPSRGNGWLLESVPPTAPAEPQPTSEIVAQAAIRAPSGGNVQPW
MLBr_01751|M.leprae_Br4923 QLTEPDMARHRP----ANPTQCSELALSGIEGVIATAAIRAPSGGNLQPW
MSMEG_3462|M.smegmatis_MC2_155 NIYVVTGDALAALKKRATERVAMGVPWDEREYDMYPATMTSPYADRRAAF
Mvan_1213|M.vanbaalenii_PYR-1 HIYVVTGAPLAQMKKLATERVAAGDPWDEREYVMYPPVLKSPYHERRATF
MAB_2661c|M.abscessus_ATCC_199 HVYVLSGARLAELKERIARRVIAGDRGDALEVAMYPQPLDSPYRERLYDF
MMAR_1739|M.marinum_M HVVFTSGAARDRLVAAMLERARSEPPNVAR--------LPPAFTHLRSAL
MUL_1982|M.ulcerans_Agy99 --------------------------------------MPPAFTHLRSAL
Mflv_1262|M.gilvum_PYR-GCK RFIVLDGPEQRAAVAQAAQ---------------------IALQSIESIY
TH_1618|M.thermoresistible__bu RFIVLDAPEQRAAVAEAAQ---------------------IALHSIESIY
MAV_0933|M.avium_104 RFVVLRSPEQRAVVAKAAA---------------------QALEVIEPVY
Mb1390c|M.bovis_AF2122/97 HVVAKQHSLTIRLAPEHTSAMDIAFRGSAVAVG------AAMFNARVAAA
Rv1355c|M.tuberculosis_H37Rv HVVAKQHSLTIRLAPEHTSAMDIAFRGSAVAVG------AAMFNARVAAA
MLBr_01751|M.leprae_Br4923 HIDAGPDALVIRIAPEHTDSLDVGFRGSAVAVG------AALFNARVAAA
MSMEG_3462|M.smegmatis_MC2_155 GKERYSALGIARDDWEA---------------------RQRAAIANWDCF
Mvan_1213|M.vanbaalenii_PYR-1 GRERYSALGIEREDWEA---------------------RQRAAIANWDCF
MAB_2661c|M.abscessus_ATCC_199 GHRRYGALGIDHDDHDA---------------------RAAVRAGNWACF
MMAR_1739|M.marinum_M GAQVYGAMGIARDDTQA---------------------RQTAVLRNWEFF
MUL_1982|M.ulcerans_Agy99 GAQVYGAMGIARDDTQA---------------------RQTAVLRNWEFF
Mflv_1262|M.gilvum_PYR-GCK GMTRPAPEDDSRSARNN---------------------RATYELHDRAG-
TH_1618|M.thermoresistible__bu GMSRPADDDRSRAARNN---------------------RATYELHDRAG-
MAV_0933|M.avium_104 GMSRPAPDDHSRRARTY---------------------RATYELHDRAG-
Mb1390c|M.bovis_AF2122/97 AHRVLGSVEFDESQPDSPLQATMHFGRGDDPSLAALYRPMLLRTTNRHHG
Rv1355c|M.tuberculosis_H37Rv AHRVLGSVEFDESQPDSPLQATMHFGRGDDPSLAALYRPMLLRTTNRHHG
MLBr_01751|M.leprae_Br4923 AHGVLGPVSLAENVDGAPLRVTLSLGDGWNPDLAAVYEPMLVRETNRNHG
. . . :
MSMEG_3462|M.smegmatis_MC2_155 GAPAALFCYIDRGLGPAQWADLGMY--LQTVMLLLRAEGLHSCPQMAWSQ
Mvan_1213|M.vanbaalenii_PYR-1 GAPAALFCYIDRDLGRPQWSDLGMY--LQTVMLLLRAEGLHSCPQMAWSQ
MAB_2661c|M.abscessus_ATCC_199 GASTALFCYLDRDMPPPQWGDAGMY--LQTIMLLLRAEGLDSCPQIAWAE
MMAR_1739|M.marinum_M RAPLGGIVSMHQELGLVDSMGVGMF--LQNLMLALTARGLGTCVQVSIAG
MUL_1982|M.ulcerans_Agy99 RAPLGGIVSMHQELGLVDSMGVGMF--LQNLMLALTARGLGTCVQVSIAG
Mflv_1262|M.gilvum_PYR-GCK EFTSVLFVAYKNEFSSEFLQGGSIYPALQNFYLAARAQGLGACITS-WAS
TH_1618|M.thermoresistible__bu EYTSVLFTAFKNEFSSELLQGGSIYPAMQNFYLAARAQGLGACFTS-WAS
MAV_0933|M.avium_104 EFTSVLFAQAHYPTASELLLGGSIFPAMQNFLLAARAQGLGACLTS-WAS
Mb1390c|M.bovis_AF2122/97 MPGHVHPATVELLTNTAAAEGARLQLLLSRNEIDRAATILAAADRIRYLT
Rv1355c|M.tuberculosis_H37Rv MPGHVHPATVELLTNTAAAEGARLQLLLSRNEIDRAATILAAADRIRYLT
MLBr_01751|M.leprae_Br4923 KPTMVLTETIDVLHAAAVAEGARLHLLTARDDIVRAATILAAADRSRYLT
. . : : * * :.
MSMEG_3462|M.smegmatis_MC2_155 VR--TTVAEAVSPPPRLMLFCGMSIGYEDP----SVDYVRTGRAPLKETV
Mvan_1213|M.vanbaalenii_PYR-1 VR--STVAQVLSPPDELMLFCGMSIGHEDT----SVGYVPTGRSALAETV
MAB_2661c|M.abscessus_ATCC_199 YH--RTVAEVIAPPPQRVLYCGMSIGYRNP----ETKAPEMPRAALSETV
MMAR_1739|M.marinum_M YP--EIVRKQVGIPSHLTILCGLAIGYPDPDF--AGNQLRVGRDDVAEHV
MUL_1982|M.ulcerans_Agy99 YP--EIVRKQVGIPSHLTILCGLAIGYPDPDF--AGNQLRVGRDDVAEHV
Mflv_1262|M.gilvum_PYR-GCK YGGEQALREAVGIPDEWFLAGHVVVGWPRG------KHGPVRRRPLSDVV
TH_1618|M.thermoresistible__bu YEGEKVLREAVGVPDDWFLAGHVVVGWPRG------RHGPVRRRPLGDVV
MAV_0933|M.avium_104 YGGEQLLREAVGVPEGWMIAGHIVVGWPKG------KHGPLRRRPLAEFV
Mb1390c|M.bovis_AF2122/97 PRLHEEMMSELRWPGDPSLDAGIDVRSLELDSGELRVLDILRRSDVVARL
Rv1355c|M.tuberculosis_H37Rv PRLHEEMMSELRWPGDPSLDAGIDVRSLELDSGELRVLDILRRSDVVARL
MLBr_01751|M.leprae_Br4923 PRLHEEMISELRWPGDSFPDTGIDVRSLEMDWHQLAAFDVLRRTDVMELL
: . : * : : * : :
MSMEG_3462|M.smegmatis_MC2_155 TFVQ----------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 TFVNG---------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 TFL-----------------------------------------------
MMAR_1739|M.marinum_M VFLDD---------------------------------------------
MUL_1982|M.ulcerans_Agy99 VFLDD---------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK FRNHWDPERADITYGRGARPRGK---------------------------
TH_1618|M.thermoresistible__bu FRNRWDPDRADITYGRGARPKRR---------------------------
MAV_0933|M.avium_104 NLDRWDAPADGLLSGL----------------------------------
Mb1390c|M.bovis_AF2122/97 AQWDCGTALEDNTNERVSASSALAIVYVDGATLTDFARGGSAMQAVWIVA
Rv1355c|M.tuberculosis_H37Rv AQWDCGTALEDNTNERVSASSALAIVYVDGATLTDFARGGSAMQAVWIVA
MLBr_01751|M.leprae_Br4923 AQWNVGAALGQDTHDRVVASSALAVISVPGHALADYARGGSAVEAIWVAA
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------------------------
TH_1618|M.thermoresistible__bu --------------------------------------------------
MAV_0933|M.avium_104 --------------------------------------------------
Mb1390c|M.bovis_AF2122/97 QQHGLAVQPMSPIFLYARGRHDLDQASPHFAAQLHRLQLDFRELVKPGKE
Rv1355c|M.tuberculosis_H37Rv QQHGLAVQPMSPIFLYARGRHDLDQASPHFAAQLHRLQLDFRELVKPGKE
MLBr_01751|M.leprae_Br4923 QRYGFAVQPISPVFLYAHSVDELHALSAQFADELGQLGKDFRSLARIPAD
MSMEG_3462|M.smegmatis_MC2_155 --------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------
MMAR_1739|M.marinum_M --------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------
Mflv_1262|M.gilvum_PYR-GCK --------------------------------
TH_1618|M.thermoresistible__bu --------------------------------
MAV_0933|M.avium_104 --------------------------------
Mb1390c|M.bovis_AF2122/97 GHEVLIFRLFHAPPPSVCSRRRVRHAIPEPHR
Rv1355c|M.tuberculosis_H37Rv GHEVLIFRLFHAPPPSVCSRRRVRHAIPEPHR
MLBr_01751|M.leprae_Br4923 NSLVLVLRLTVAGPASVRSRRSFERIRLLSG-