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MYDLDETIRLRRSTRMFLPRPVPRRLVQEALELAMCAPSNSNVQPWHVVFTSGAARDRLVAAMLERARSE PPNVARLPPAFTHLRSALGAQVYGAMGIARDDTQARQTAVLRNWEFFRAPLGGIVSMHQELGLVDSMGVG MFLQNLMLALTARGLGTCVQVSIAGYPEIVRKQVGIPSHLTILCGLAIGYPDPDFAGNQLRVGRDDVAEH VVFLDD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1739 | - | - | 100% (216) | nitroreductase |
| M. marinum M | MMAR_4721 | - | 2e-09 | 28.95% (190) | nitroreductase |
| M. marinum M | MMAR_2938 | - | 4e-08 | 28.71% (202) | nitroreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 3e-07 | 43.33% (60) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4892 | - | 2e-06 | 34.94% (83) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 3e-07 | 43.33% (60) | oxidoreductase |
| M. leprae Br4923 | MLBr_00418 | - | 3e-07 | 29.15% (223) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2661c | - | 4e-25 | 32.73% (220) | putative nitroreductase |
| M. avium 104 | MAV_4225 | - | 1e-10 | 29.41% (187) | F420-0--gamma-glutamyl ligase |
| M. smegmatis MC2 155 | MSMEG_2354 | - | 4e-69 | 59.91% (212) | oxidoreductase |
| M. thermoresistible (build 8) | TH_0777 | - | 6e-10 | 28.12% (192) | PROBABLE F420 BIOSYNTHESIS PROTEIN FBIB |
| M. ulcerans Agy99 | MUL_1982 | - | 6e-78 | 100.00% (140) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1213 | - | 1e-30 | 33.03% (221) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4225|M.avium_104 MSPAG--------EHGTAAPIEILPVAGLPEFRPGDDLGAAVAKAAPWLR
TH_0777|M.thermoresistible__bu VSTAGGAGQTGSGDHGTAAAIELFPVTGLPQFCPGDDLTAAVAAAAPWLR
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00418|M.leprae_Br4923 --------------------------------------------------
Mflv_4892|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4225|M.avium_104 DGDVVVVTSKAVSKCEGRLVPAPADPEERDRLRRKLVDEEAVRVLARKGR
TH_0777|M.thermoresistible__bu DNDVVVVTSKVVSKCEGRIIAAPADPEQRDALRRKLIDEEAVRVLARKGR
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00418|M.leprae_Br4923 --------------------------------------------------
Mflv_4892|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4225|M.avium_104 TLITENRHGLVQAAAGVDGSNVGRDELALLPLDPDASAAALRARLRELLG
TH_0777|M.thermoresistible__bu TLITENALGLVQAAAGVDGSNVAATELALLPVDPDASAAALRAGLRQRLG
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00418|M.leprae_Br4923 --------------------------------------------------
Mflv_4892|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4225|M.avium_104 VEVAVLVTDTMGRAWRNGQTDAAVGAAGLAVLHGYSGAVDQHGNELLVTE
TH_0777|M.thermoresistible__bu VDVGVIITDTMGRAWRTGQTDFAIGAAGLTVLHGYAGSHDRHGNELFVTE
Mb3403c|M.bovis_AF2122/97 -----------------------------------------------MTL
Rv3368c|M.tuberculosis_H37Rv -----------------------------------------------MTL
MLBr_00418|M.leprae_Br4923 --------------------------------------------------
Mflv_4892|M.gilvum_PYR-GCK -----------------------------------------------MTL
MMAR_1739|M.marinum_M --------------------------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2661c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4225|M.avium_104 VAIADEIAAAADLVKGKLTAMPVAVVRGLSVTDDGSTARQLLRPGTEDLF
TH_0777|M.thermoresistible__bu VAVADEIAAAADLVKGKLTDVPVAVVRGLTLRDDGSTARTLVRPGQDDLF
Mb3403c|M.bovis_AF2122/97 NLSVDEVLTTTRSVRKRLDFD-----------------------------
Rv3368c|M.tuberculosis_H37Rv NLSVDEVLTTTRSVRKRLDFD-----------------------------
MLBr_00418|M.leprae_Br4923 -MSVDEVLTTTRSVRKRLDFD-----------------------------
Mflv_4892|M.gilvum_PYR-GCK NLSADEVLTTTRSVRKRLDFD-----------------------------
MMAR_1739|M.marinum_M MYDLDETIRLRRSTRMFLP-------------------------------
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 -MELAEAVRARRSTRKFLPD------------------------------
MAB_2661c|M.abscessus_ATCC_199 -MDVYDAVASRRSVREFVD-------------------------------
Mvan_1213|M.vanbaalenii_PYR-1 -MDVYEAVRSRRAVRGFTD-------------------------------
MAV_4225|M.avium_104 WLGTAEAIELGRRQAQLLRRSVRRFSAEPVPAELVREAVAEALTAPAPHH
TH_0777|M.thermoresistible__bu WLGTEEAIRLGRSQAQLLRRSVRRFDSEPVPADLIEAAVAEALTAPAPHH
Mb3403c|M.bovis_AF2122/97 ---------------------------KPVPRDVLMECLELALQAPTGSN
Rv3368c|M.tuberculosis_H37Rv ---------------------------KPVPRDVLMECLELALQAPTGSN
MLBr_00418|M.leprae_Br4923 ---------------------------KPVPRDVLMECLQLALQAPTGSN
Mflv_4892|M.gilvum_PYR-GCK ---------------------------RPVPREVLNECLEIALQAPTGSN
MMAR_1739|M.marinum_M ---------------------------RPVPRRLVQEALELAMCAPSNSN
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2354|M.smegmatis_MC2_155 ---------------------------KPVPHELIEEALTLAMRAPSNSN
MAB_2661c|M.abscessus_ATCC_199 ---------------------------RPVSPATLTRVLTAAARAPSGGN
Mvan_1213|M.vanbaalenii_PYR-1 ---------------------------EPVPQAVLERVLAAAAWAPSGSN
MAV_4225|M.avium_104 TRPVRFVWLQTPAVRTRLLDAMKDKWRADLAGDG--------RPAESIER
TH_0777|M.thermoresistible__bu TRPVRFVWLQNWTARTRLLDRMKDRWRADLAGDG--------ASPEAVER
Mb3403c|M.bovis_AF2122/97 SQGWQWVFVEDAAKKKAIADVYLANARGYLSGPA--------PEYPDGDT
Rv3368c|M.tuberculosis_H37Rv SQGWQWVFVEDAAKKKAIADVYLANARGYLSGPA--------PEYPDGDT
MLBr_00418|M.leprae_Br4923 SQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPA--------PEYPEGDT
Mflv_4892|M.gilvum_PYR-GCK AQGWQFVFVDDPEKKKALADIYRIAADPYLEAEK--------PTF--GDV
MMAR_1739|M.marinum_M VQPWHVVFTSGAARDRLVAAMLERARSEPPNVAR--------LPPAFTHL
MUL_1982|M.ulcerans_Agy99 ------------------------------------------MPPAFTHL
MSMEG_2354|M.smegmatis_MC2_155 VQPWRVYFASGERRERLVAALTAEVRARRPTSLG--------LPDAFQHL
MAB_2661c|M.abscessus_ATCC_199 LQPWHVYVLSGARLAELKERIARRVIAGDRGDALEVAMYPQPLDSPYRER
Mvan_1213|M.vanbaalenii_PYR-1 LQPWHIYVVTGAPLAQMKKLATERVAAGDPWDEREYVMYPPVLKSPYHER
.
MAV_4225|M.avium_104 RVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTM-----------
TH_0777|M.thermoresistible__bu RVGRGQILYDAPELIVPFLVADGAHHYPDARRAAAEHTM-----------
Mb3403c|M.bovis_AF2122/97 RGERMGRVRDSATYLAEHMHRAPVLLIPCLKGREDESAVGGVS-------
Rv3368c|M.tuberculosis_H37Rv RGERMGRVRDSATYLAEHMHRAPVLLIPCLKGREDESAVGGVS-------
MLBr_00418|M.leprae_Br4923 RGERMRLVRDSATYLAEHMHEVPVLLIPCLLGRAEESPLGAVS-------
Mflv_4892|M.gilvum_PYR-GCK RDERTPLVVDSAKYLAEHLHEAPVMLIPCLEGRPDGAPAGMSAG------
MMAR_1739|M.marinum_M RSALGAQVYGAMGIARDDTQARQTAVLRNWEFFRAPLGGIVSMHQELGLV
MUL_1982|M.ulcerans_Agy99 RSALGAQVYGAMGIARDDTQARQTAVLRNWEFFRAPLGGIVSMHQELGLV
MSMEG_2354|M.smegmatis_MC2_155 RSQLGALVYGSMGIARADTEARWAAQLRNWEFFGAPLAGVVCMHRDLGLV
MAB_2661c|M.abscessus_ATCC_199 LYDFGHRRYGALGIDHDDHDARAAVRAGNWACFGASTALFCYLDRDMPPP
Mvan_1213|M.vanbaalenii_PYR-1 RATFGRERYSALGIEREDWEARQRAAIANWDCFGAPAALFCYIDRDLGRP
.:
MAV_4225|M.avium_104 FTVAVGAAVQALLVGLAVRGLGSCWIGSTIFAA--DLVRAVLGLP-ADWE
TH_0777|M.thermoresistible__bu FTVAGGAAVQALLVALAVREIGSCWVGSTIFAP--EVVRTELGLP-DDWE
Mb3403c|M.bovis_AF2122/97 FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
Rv3368c|M.tuberculosis_H37Rv FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
MLBr_00418|M.leprae_Br4923 YWASLFPAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYS
Mflv_4892|M.gilvum_PYR-GCK FWGSLLPAVWSFMLALRSRGLGSAWTTLHLIGDGEKQAAEVLGIPFDKYS
MMAR_1739|M.marinum_M DSMGVGMFLQNLMLALTARGLGTCVQVSIAGYP--EIVRKQVGIP-SHLT
MUL_1982|M.ulcerans_Agy99 DSMGVGMFLQNLMLALTARGLGTCVQVSIAGYP--EIVRKQVGIP-SHLT
MSMEG_2354|M.smegmatis_MC2_155 DSVGVGMFLQTFLLALTERGIGSCVQVSVAMCA--DVLRAELDIP-DELT
MAB_2661c|M.abscessus_ATCC_199 QWGDAGMYLQTIMLLLRAEGLDSCPQIAWAEYH--RTVAEVIAPP-PQRV
Mvan_1213|M.vanbaalenii_PYR-1 QWSDLGMYLQTVMLLLRAEGLHSCPQMAWSQVR--STVAQVLSPP-DELM
: . : * . : :. : * .
MAV_4225|M.avium_104 PLGAIAIGYAAEPAGPRDPADPGDLLIRK------
TH_0777|M.thermoresistible__bu PLGAVAIGYPAEPAGPRDPAPTEGLLVFR------
Mb3403c|M.bovis_AF2122/97 QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW---
Rv3368c|M.tuberculosis_H37Rv QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW---
MLBr_00418|M.leprae_Br4923 QGGLFPIAYTKGTDFRPANRLPAENVTHWDIW---
Mflv_4892|M.gilvum_PYR-GCK QGGLFPIAYTKGTDFKKAKRLPAEQLTHWNTW---
MMAR_1739|M.marinum_M ILCGLAIGYPDPDFAGNQLRVGRDDVAEHVVFLDD
MUL_1982|M.ulcerans_Agy99 ILCGLAIGYPDPDFAGNQLRVGRDDVAEHVVFLDD
MSMEG_2354|M.smegmatis_MC2_155 VLCGMSIGYADPAFPANHLDIPRNPVEQNVTFYS-
MAB_2661c|M.abscessus_ATCC_199 LYCGMSIGYRNP--ETKAPEMPRAALSETVTFL--
Mvan_1213|M.vanbaalenii_PYR-1 LFCGMSIGHEDT--SVGYVPTGRSALAETVTFVNG
..*.: :