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MSDVYEAVISRRAVRGFTDRPVPKAVLARVLSAAAWSPSSSNTQPWNIYVVTGDALAALKKRATERVAMG VPWDEREYDMYPATMTSPYADRRAAFGKERYSALGIARDDWEARQRAAIANWDCFGAPAALFCYIDRGLG PAQWADLGMYLQTVMLLLRAEGLHSCPQMAWSQVRTTVAEAVSPPPRLMLFCGMSIGYEDPSVDYVRTGR APLKETVTFVQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3462 | - | - | 100% (221) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2354 | - | 4e-30 | 34.51% (226) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6505 | - | 7e-26 | 36.11% (216) | NfnB protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 7e-05 | 30.54% (167) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1262 | - | 1e-09 | 27.27% (220) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 7e-05 | 30.54% (167) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2661c | - | 2e-68 | 56.42% (218) | putative nitroreductase |
| M. marinum M | MMAR_1739 | - | 1e-31 | 35.14% (222) | nitroreductase |
| M. avium 104 | MAV_0933 | - | 5e-08 | 27.36% (212) | nitroreductase family protein |
| M. thermoresistible (build 8) | TH_1618 | - | 4e-08 | 44.00% (50) | nitroreductase family protein |
| M. ulcerans Agy99 | MUL_1982 | - | 1e-20 | 39.23% (130) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1213 | - | 1e-100 | 79.82% (218) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3462|M.smegmatis_MC2_155 ------MSDVYEAVISRRAVRG--FTDRPVPKAVLARVLSAAAWSPSSSN
Mvan_1213|M.vanbaalenii_PYR-1 -------MDVYEAVRSRRAVRG--FTDEPVPQAVLERVLAAAAWAPSGSN
MAB_2661c|M.abscessus_ATCC_199 -------MDVYDAVASRRSVRE--FVDRPVSPATLTRVLTAAARAPSGGN
MMAR_1739|M.marinum_M ------MYDLDETIRLRRSTRM--FLPRPVPRRLVQEALELAMCAPSNSN
MUL_1982|M.ulcerans_Agy99 --------------------------------------------------
Mb3403c|M.bovis_AF2122/97 ---MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSN
Rv3368c|M.tuberculosis_H37Rv ---MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSN
Mflv_1262|M.gilvum_PYR-GCK MDMPHPTDNVWEVLSTARSIRR--FTDEPVDSATLDRCLQAATWAPNGAN
TH_1618|M.thermoresistible__bu --MPHPTNDVWEVLSTARSIRR--FTDEPVDDATLQRCLQAATWAPNGAN
MAV_0933|M.avium_104 ------------MMSTARTIRR--FTDEPVDDATLARCLGAARWAPSGAN
MSMEG_3462|M.smegmatis_MC2_155 TQPWNIYVVTGDALAALKKRATERVAMGVPWDEREYDMYPATMTSPYADR
Mvan_1213|M.vanbaalenii_PYR-1 LQPWHIYVVTGAPLAQMKKLATERVAAGDPWDEREYVMYPPVLKSPYHER
MAB_2661c|M.abscessus_ATCC_199 LQPWHVYVLSGARLAELKERIARRVIAGDRGDALEVAMYPQPLDSPYRER
MMAR_1739|M.marinum_M VQPWHVVFTSGAARDRLVAAMLERARSEPPNVAR--------LPPAFTHL
MUL_1982|M.ulcerans_Agy99 ------------------------------------------MPPAFTHL
Mb3403c|M.bovis_AF2122/97 SQGWQWVFVEDAAKKKAIADVYLANARG---------------YLSGPAP
Rv3368c|M.tuberculosis_H37Rv SQGWQWVFVEDAAKKKAIADVYLANARG---------------YLSGPAP
Mflv_1262|M.gilvum_PYR-GCK AQLWRFIVLDGPEQRAAVAQAAQIALQS---------------IESIYGM
TH_1618|M.thermoresistible__bu AQLWRFIVLDAPEQRAAVAEAAQIALHS---------------IESIYGM
MAV_0933|M.avium_104 AQGWRFVVLRSPEQRAVVAKAAAQALEV---------------IEPVYGM
.
MSMEG_3462|M.smegmatis_MC2_155 RAAFGKERYSALGIARDDWEARQRAAIANWDCFGAPAALFCYIDRGLGPA
Mvan_1213|M.vanbaalenii_PYR-1 RATFGRERYSALGIEREDWEARQRAAIANWDCFGAPAALFCYIDRDLGRP
MAB_2661c|M.abscessus_ATCC_199 LYDFGHRRYGALGIDHDDHDARAAVRAGNWACFGASTALFCYLDRDMPPP
MMAR_1739|M.marinum_M RSALGAQVYGAMGIARDDTQARQTAVLRNWEFFRAPLGGIVSMHQELGLV
MUL_1982|M.ulcerans_Agy99 RSALGAQVYGAMGIARDDTQARQTAVLRNWEFFRAPLGGIVSMHQELGLV
Mb3403c|M.bovis_AF2122/97 EYPDGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKGREDESAVGGVS
Rv3368c|M.tuberculosis_H37Rv EYPDGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKGREDESAVGGVS
Mflv_1262|M.gilvum_PYR-GCK TRPAPEDDSRSARNNRATYELHDRAGEFTSVLFVAYKNEFSSEFLQG---
TH_1618|M.thermoresistible__bu SRPADDDRSRAARNNRATYELHDRAGEYTSVLFTAFKNEFSSELLQG---
MAV_0933|M.avium_104 SRPAPDDHSRRARTYRATYELHDRAGEFTSVLFAQAHYPTASELLLG---
: :
MSMEG_3462|M.smegmatis_MC2_155 QWADLGMYLQTVMLLLRAEGLHSCPQ--MAWSQVRTTVAEAVSPPPRLML
Mvan_1213|M.vanbaalenii_PYR-1 QWSDLGMYLQTVMLLLRAEGLHSCPQ--MAWSQVRSTVAQVLSPPDELML
MAB_2661c|M.abscessus_ATCC_199 QWGDAGMYLQTIMLLLRAEGLDSCPQ--IAWAEYHRTVAEVIAPPPQRVL
MMAR_1739|M.marinum_M DSMGVGMFLQNLMLALTARGLGTCVQ--VSIAGYPEIVRKQVGIPSHLTI
MUL_1982|M.ulcerans_Agy99 DSMGVGMFLQNLMLALTARGLGTCVQ--VSIAGYPEIVRKQVGIPSHLTI
Mb3403c|M.bovis_AF2122/97 FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
Rv3368c|M.tuberculosis_H37Rv FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
Mflv_1262|M.gilvum_PYR-GCK --GSIYPALQNFYLAARAQGLGACITSWASYG-GEQALREAVGIP-DEWF
TH_1618|M.thermoresistible__bu --GSIYPAMQNFYLAARAQGLGACFTSWASYE-GEKVLREAVGVP-DDWF
MAV_0933|M.avium_104 --GSIFPAMQNFLLAARAQGLGACLTSWASYG-GEQLLREAVGVP-EGWM
. : .. * :.** :* : . :. *
MSMEG_3462|M.smegmatis_MC2_155 FCG-MSIGYEDP--SVDYVRTGRAPLKETVTFVQ----------------
Mvan_1213|M.vanbaalenii_PYR-1 FCG-MSIGHEDT--SVGYVPTGRSALAETVTFVNG---------------
MAB_2661c|M.abscessus_ATCC_199 YCG-MSIGYRNP--ETKAPEMPRAALSETVTFL-----------------
MMAR_1739|M.marinum_M LCG-LAIGYPDPDFAGNQLRVGRDDVAEHVVFLDD---------------
MUL_1982|M.ulcerans_Agy99 LCG-LAIGYPDPDFAGNQLRVGRDDVAEHVVFLDD---------------
Mb3403c|M.bovis_AF2122/97 QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW------------------
Rv3368c|M.tuberculosis_H37Rv QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW------------------
Mflv_1262|M.gilvum_PYR-GCK LAGHVVVGWPRGK-HGPVRRRPLSDVVFRNHWDPERADITYGRGARPRGK
TH_1618|M.thermoresistible__bu LAGHVVVGWPRGR-HGPVRRRPLGDVVFRNRWDPDRADITYGRGARPKRR
MAV_0933|M.avium_104 IAGHIVVGWPKGK-HGPLRRRPLAEFVNLDRWDAPADGLLSGL-------
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