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M. thermoresistible (build 8) TH_0777 ()

annotation: PROBABLE F420 BIOSYNTHESIS PROTEIN FBIB
coordinates: 1628139 - 1629512
length: 458

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0777-100% (458)PROBABLE F420 BIOSYNTHESIS PROTEIN FBIB
M. thermoresistible (build 8)TH_3507-2e-0827.72% (184) PUTATIVE putative nitroreductase
M. thermoresistible (build 8)TH_2448-9e-0723.86% (197) PUTATIVE nitroreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3290fbiB0.076.35% (444) F420-0--gamma-glutamyl ligase
M. gilvum PYR-GCKMflv_4731-0.077.03% (444) F420-0--gamma-glutamyl ligase
M. tuberculosis H37RvRv3262fbiB0.076.35% (444) F420-0--gamma-glutamyl ligase
M. leprae Br4923MLBr_00758-0.073.20% (444) F420-0--gamma-glutamyl ligase
M. abscessus ATCC 19977MAB_3608-1e-17968.39% (446) F420-0--gamma-glutamyl ligase
M. marinum MMMAR_1280fbiB0.075.23% (444) F420 biosynthesis protein FbiB
M. avium 104MAV_4225-0.077.93% (444) F420-0--gamma-glutamyl ligase
M. smegmatis MC2 155MSMEG_1829-0.078.97% (447) F420-0--gamma-glutamyl ligase
M. ulcerans Agy99MUL_2607fbiB0.074.55% (444) F420-0--gamma-glutamyl ligase
M. vanbaalenii PYR-1Mvan_1732-0.079.50% (444) F420-0--gamma-glutamyl ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3290|M.bovis_AF2122/97            MTG---------PEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLR
Rv3262|M.tuberculosis_H37Rv         MTG---------PEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLR
MLBr_00758|M.leprae_Br4923          MTSSDSHRSAPSPEHGTASTIEILPVAGLPEFRPGDDLSAALAAAAPWLR
MMAR_1280|M.marinum_M               MSGPAL---PPTGEHGTASAIEILPVEGLPEFRPGDELSAAIATAAPWLR
MUL_2607|M.ulcerans_Agy99           MSGPAL---PPTGEHGTVSAIEILPVEGLPEFRPGNELSAAIATAAPWLR
MAV_4225|M.avium_104                MS--------PAGEHGTAAPIEILPVAGLPEFRPGDDLGAAVAKAAPWLR
Mflv_4731|M.gilvum_PYR-GCK          -----------MTDHGTSARVEVLPVPGLPEFRPGDDLAAAIADAAPWLR
Mvan_1732|M.vanbaalenii_PYR-1       -----------MTDHGTSARVELLPVPGLPEFRPGDNLSAAIAEAAPWLQ
TH_0777|M.thermoresistible__bu      VSTAGGAGQTGSGDHGTAAAIELFPVTGLPQFCPGDDLTAAVAAAAPWLR
MSMEG_1829|M.smegmatis_MC2_155      ------MSAAANAEHGAADRVEILPVPGLPEFRPGDDLVGSLAEAAPWLR
MAB_3608|M.abscessus_ATCC_1997      MTPPADS---PAPEHGSAAPVQILPVTGLPEFRPGDDVAAAIAGAAPWLR
                                                 :**:   ::::** ***:* **::: .::* *****:

Mb3290|M.bovis_AF2122/97            DGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDR
Rv3262|M.tuberculosis_H37Rv         DGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDR
MLBr_00758|M.leprae_Br4923          DGDVVVVTSKVVSKCEGRLVPAPEDTRGRNELRRKLINDETIRVLARKGR
MMAR_1280|M.marinum_M               DGDVVVVTSKVVSKCEGRLVTAPADEEARDQLRRKLVDDEAVRVLARKGR
MUL_2607|M.ulcerans_Agy99           DGDVVVVTSKVVSKCEGRLVTAPADEEARDQLRRKLVDDEAVRVLARKGR
MAV_4225|M.avium_104                DGDVVVVTSKAVSKCEGRLVPAPADPEERDRLRRKLVDEEAVRVLARKGR
Mflv_4731|M.gilvum_PYR-GCK          DDDVVVVTSKVLSKTEGRMVEAPTDPDERDALRRKLIDGEAVRVLARKGR
Mvan_1732|M.vanbaalenii_PYR-1       DDDVLVVTSKVLSKTEGRMVAAPADPEERDALRRKLIDSEAVRVLARKGR
TH_0777|M.thermoresistible__bu      DNDVVVVTSKVVSKCEGRIIAAPADPEQRDALRRKLIDEEAVRVLARKGR
MSMEG_1829|M.smegmatis_MC2_155      DGDVLVVTSKVVSKCEGRIVAAPSDPEERDTLRRKLIDDEAVRVLARKGR
MAB_3608|M.abscessus_ATCC_1997      DGDVIVITSKIISKAEGRIVAAPTDPEARDTLRRKLIDSESIRVLARKGK
                                    *.**:*:*** :** ***:: ** *   *: *****:: *::******.:

Mb3290|M.bovis_AF2122/97            TLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLG
Rv3262|M.tuberculosis_H37Rv         TLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLG
MLBr_00758|M.leprae_Br4923          TLIIENGLGLVQAAAGVDGSNVGRGELALLPVNPDASAAVLRIGLRAMLG
MMAR_1280|M.marinum_M               TLITESRLGLVQAAAGVDGSNVDRSELALLPVDPDASAAALRTGLRERLG
MUL_2607|M.ulcerans_Agy99           TLITESRLGLVQAAAGVDGSNVDRSELALLPVDPDASAAALRTGLRERLG
MAV_4225|M.avium_104                TLITENRHGLVQAAAGVDGSNVGRDELALLPLDPDASAAALRARLRELLG
Mflv_4731|M.gilvum_PYR-GCK          TLITENALGLVQAAAGVDGSNVDSNELALLPVDPDGSAAELVAALHERLG
Mvan_1732|M.vanbaalenii_PYR-1       TLITENALGLVQAAAGVDGSNVESNELALLPVDPDGSAAALVAALRERLG
TH_0777|M.thermoresistible__bu      TLITENALGLVQAAAGVDGSNVAATELALLPVDPDASAAALRAGLRQRLG
MSMEG_1829|M.smegmatis_MC2_155      TLITENAIGLVQAAAGVDGSNVGSTELALLPVDPDRSAATLREGLRERLG
MAB_3608|M.abscessus_ATCC_1997      TLITENTIGIVQAAAGIDASNVDTAELVLLPTDPDASAAAVRLALSQRLG
                                    *** *.  *:******:*.***   **.*** :** *** :   *   **

Mb3290|M.bovis_AF2122/97            VTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTE
Rv3262|M.tuberculosis_H37Rv         VTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTE
MLBr_00758|M.leprae_Br4923          VNVAVVITDTMGRAWRNGQTDVAIGAAGLAVLHNYSGAVDRYGNELVVTE
MMAR_1280|M.marinum_M               VTVAVVITDTMGRAWRNGQIDAAVGAAGVSVLHNYSGATDRHGNELIVTE
MUL_2607|M.ulcerans_Agy99           VTVAVVITDTMGRAWRNGQIDAAVGAAGVSVLHNYSGATDRHGNELIVTE
MAV_4225|M.avium_104                VEVAVLVTDTMGRAWRNGQTDAAVGAAGLAVLHGYSGAVDQHGNELLVTE
Mflv_4731|M.gilvum_PYR-GCK          VRVAVVVTDTMGRAWRTGQTDVAIGAAGLTVLHAYAGEHDQHGNELIVTE
Mvan_1732|M.vanbaalenii_PYR-1       VRIGVVVTDTMGRAWRTGQTDVAIGAAGLTVLHAYAGERDQHGNELIVTE
TH_0777|M.thermoresistible__bu      VDVGVIITDTMGRAWRTGQTDFAIGAAGLTVLHGYAGSHDRHGNELFVTE
MSMEG_1829|M.smegmatis_MC2_155      VTVGVVITDTMGRAWRTGQTDFAIGASGLTVLQGYAGSRDRHGNELVVTE
MAB_3608|M.abscessus_ATCC_1997      VKVAVVITDTMGRAWRNGQTDAAIGSAGIPVLYGYAGAKDKHGNELQVTE
                                    * :.*::*********.** * *:*::*:.**  *:*  * :**** ***

Mb3290|M.bovis_AF2122/97            VAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLF
Rv3262|M.tuberculosis_H37Rv         VAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLF
MLBr_00758|M.leprae_Br4923          IAVADEVAAATDLVKGKLTAMPVAVVRGLSPTDDGSTAQHLLRNGPDDLF
MMAR_1280|M.marinum_M               IAVADEIAAAADLVKGKLTAMPVAVVRGLPVRDDGSTARNLVRPGEEDLF
MUL_2607|M.ulcerans_Agy99           IAVADEIAAAADLVKGKLTAMPVAVVRGLPVRDDGSTARNLVRPGEEDLF
MAV_4225|M.avium_104                VAIADEIAAAADLVKGKLTAMPVAVVRGLSVTDDGSTARQLLRPGTEDLF
Mflv_4731|M.gilvum_PYR-GCK          IAVADEIAAAADLVKGKLTAVPVAVVRGLAVRDDGSSARNLVRAGEEDLF
Mvan_1732|M.vanbaalenii_PYR-1       IAVADEIAAAADLVKGKLTAVPVAVVRGLSLRDDGSSARNLVRAGEEDLF
TH_0777|M.thermoresistible__bu      VAVADEIAAAADLVKGKLTDVPVAVVRGLTLRDDGSTARTLVRPGQDDLF
MSMEG_1829|M.smegmatis_MC2_155      VAVADEIAAAADLVKGKLTAIPVAVVRGLRLPDDGSTAHRLVRAGEDDLF
MAB_3608|M.abscessus_ATCC_1997      VAIADEISAAADLVKGKLTDVPVAVVRGLTLLDDGSAASDLLRSGPDDLF
                                    :*:***::**:********  *******:   ****:*  *:* * :***

Mb3290|M.bovis_AF2122/97            WLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHH
Rv3262|M.tuberculosis_H37Rv         WLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHH
MLBr_00758|M.leprae_Br4923          WLGTTEALELGRQQAQLLRRSVRQFSDEPIAAELIETAVAEALTAPAPHH
MMAR_1280|M.marinum_M               WLGTAEAIELGHQQAQLMRRSIRQFANEPVPPQLLEAAVAEALTAPAPHH
MUL_2607|M.ulcerans_Agy99           WLGTAEAIELGHQQAQLMRRSIRQFADEPVPPQLLEAAVAEALTAPAPHH
MAV_4225|M.avium_104                WLGTAEAIELGRRQAQLLRRSVRRFSAEPVPAELVREAVAEALTAPAPHH
Mflv_4731|M.gilvum_PYR-GCK          WLGTDEALALGRSQAQLLRRSVRQFSPEPVDGALIGAAVGEALTAPAPHH
Mvan_1732|M.vanbaalenii_PYR-1       WLGTEEALALGRSQAQLLRRSVRTFNSEPVPGDVIEAAVGEALTAPAPHH
TH_0777|M.thermoresistible__bu      WLGTEEAIRLGRSQAQLLRRSVRRFDSEPVPADLIEAAVAEALTAPAPHH
MSMEG_1829|M.smegmatis_MC2_155      WLGTAEAIELGRRQAQLLRRSVRRFSAEPVPHDAIEAAVGEALTAPAPHH
MAB_3608|M.abscessus_ATCC_1997      WLGTNEALEQGRREAILVRRSIRQFADIPVDPDLLREAIGEALTAPAPHH
                                    **** **:  *: :* *:***:* *   *:    :  *:.**********

Mb3290|M.bovis_AF2122/97            TRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQIL
Rv3262|M.tuberculosis_H37Rv         TRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQIL
MLBr_00758|M.leprae_Br4923          TRPVRFVWLQTPAVRTRLLDRMADKWRLDLASDALPADAIAQRVARGQIL
MMAR_1280|M.marinum_M               TRPVRFVWLQSHATRIALLDAMKDKWRHDLAGDGRSADSIERRVTRGQIL
MUL_2607|M.ulcerans_Agy99           TRPVRFVWLQSHATRIALLDAMKDKWRHDLVGDGRSADSIERRVTRGQIL
MAV_4225|M.avium_104                TRPVRFVWLQTPAVRTRLLDAMKDKWRADLAGDGRPAESIERRVARGQIL
Mflv_4731|M.gilvum_PYR-GCK          TRPVRFVWVQDGALRVGLLDEMKERWRADLLADGRDAESVERRVSRGQIL
Mvan_1732|M.vanbaalenii_PYR-1       TRPVRFVWVQDASVRVGLLDKMKDRWRADLLGDGRDPESVERRVNRGQIL
TH_0777|M.thermoresistible__bu      TRPVRFVWLQNWTARTRLLDRMKDRWRADLAGDGASPEAVERRVGRGQIL
MSMEG_1829|M.smegmatis_MC2_155      TRPVRFVWVQDSETRTRLLDRMKEQWRADLTADGLDADAVDRRVARGQIL
MAB_3608|M.abscessus_ATCC_1997      THPVRFVWVRDLTTRRALLDALKQAWAADLTADGRSPESVQKRVARGQIL
                                    *:*.****::    *  *** : : *  ** .*.  .::: :** *****

Mb3290|M.bovis_AF2122/97            YDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVR
Rv3262|M.tuberculosis_H37Rv         YDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVR
MLBr_00758|M.leprae_Br4923          YDAPEVIIPFMVPDGAHAYPDAARASAEHTMFIVAVGAAVQALLVALAVR
MMAR_1280|M.marinum_M               YDAPEVVIPMLVPDGAHTYPDGARTQAEHTMFTVAVGAAVQALLVALAVR
MUL_2607|M.ulcerans_Agy99           YDAPEVVIPMLVPDGAHTYPDGARTQAEHTMFTVAVGAAVQALLVALAVR
MAV_4225|M.avium_104                YDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVGLAVR
Mflv_4731|M.gilvum_PYR-GCK          YDAPELIIPFMVPDGAHSYPDERRTAAEHTMFTVAAGAAVQGLLVALAVR
Mvan_1732|M.vanbaalenii_PYR-1       YDAPELVIPFMVPDGAHSYPDARRTAAEHTMFTVAAGAAVQGLLVALAAR
TH_0777|M.thermoresistible__bu      YDAPELIVPFLVADGAHHYPDARRAAAEHTMFTVAGGAAVQALLVALAVR
MSMEG_1829|M.smegmatis_MC2_155      YDAPELVIPFLVPDGAHSYPDDARTAAEHTMFTVAVGAAVQGLLVALAVR
MAB_3608|M.abscessus_ATCC_1997      YDAPEIVIPFLVPDGAHDYPDDRRTAAERTMFTVAVGAAVQALLVALAAR
                                    *****:::*::*.**** ***  *: **:*** ** *****.***.**.*

Mb3290|M.bovis_AF2122/97            GLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADE----PSGLRD
Rv3262|M.tuberculosis_H37Rv         GLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADE----PSGLRD
MLBr_00758|M.leprae_Br4923          GLGSCWIGSTIFADDLVRAELELPADWEPLGAIAIGYAHE----PTDLRE
MMAR_1280|M.marinum_M               GLGSCWIGSTIFAADLVRAQLQLPADWEPLGAIAIGYAQQ----PAELRD
MUL_2607|M.ulcerans_Agy99           GLGSCWIGSTIFAADLVRAQLQLPADWEPLGAIAIGYAQQ----PAELRD
MAV_4225|M.avium_104                GLGSCWIGSTIFAADLVRAVLGLPADWEPLGAIAIGYAAE----PAGPRD
Mflv_4731|M.gilvum_PYR-GCK          GVGSCWIGSTIFAPELVRAALEVPGDWEPLGAIAIGYGTD----PVTPRE
Mvan_1732|M.vanbaalenii_PYR-1       SVGSCWIGSTIFAPDLVRAELGVPDDWEPLGAIAIGYPEA----PLAPRH
TH_0777|M.thermoresistible__bu      EIGSCWVGSTIFAPEVVRTELGLPDDWEPLGAVAIGYPAE----PAGPRD
MSMEG_1829|M.smegmatis_MC2_155      DIGSCWIGSTIFAADLVRAELELPDDWEPLGAIAIGYPEQTPQ-PLGPRD
MAB_3608|M.abscessus_ATCC_1997      QVGSCWIGSTIFAGDVVRKQLVVDSSWEPMGAIAIGYPHGYPEEGLDPRT
                                     :****:****** ::**  * :  .***:**:****           * 

Mb3290|M.bovis_AF2122/97            PVPAADLLILK
Rv3262|M.tuberculosis_H37Rv         PVPAADLLILK
MLBr_00758|M.leprae_Br4923          PVRVADLLLRK
MMAR_1280|M.marinum_M               PVHPGDLLIRK
MUL_2607|M.ulcerans_Agy99           PVHPGDLLIRK
MAV_4225|M.avium_104                PADPGDLLIRK
Mflv_4731|M.gilvum_PYR-GCK          PVPTDGLLVRR
Mvan_1732|M.vanbaalenii_PYR-1       PVPTDDLLVRR
TH_0777|M.thermoresistible__bu      PAPTEGLLVFR
MSMEG_1829|M.smegmatis_MC2_155      PVPTDELLVRK
MAB_3608|M.abscessus_ATCC_1997      PLPPGQMLVEL
                                    *     :*: