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TDYSQARAVVVGGSIGGLTTALLLRDSGFHVDVFERTPTALDGRGSGIVLQPDTVRWFQERSSQDLGDLQ TATRFVQYLDRSGDVVHREPATWTYTSWGTFYRALLADFGTEHYHYGEYACGFDQDEAEAVVRFVSGRTA AADLVVFADGITSAARERFDPDATLRYAGYIGWRGTVALSALSEPTRNTLRDAITYDVVPHSHITMYPIP GEDGLGESQRLMNYVWYRNVPAGPELTEMLIDKRGFGGSVSVHPGQVQDRYVDAIRADAAELFAPAVAET VVRTEQPYLQVLSDVRSTRMAMGRVALIGDAACASRPHAAAGTAKAAADAWTLAGALAASDGDIAAALRK WEPAQLQLSDSLLRRVVDMGDRSQFHNTWWPGDPDLRFGLYGPGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6489 | - | - | 100% (396) | hypothetical protein MSMEG_6489 |
| M. smegmatis MC2 155 | MSMEG_3841 | - | 2e-12 | 28.00% (350) | hypothetical protein MSMEG_3841 |
| M. smegmatis MC2 155 | MSMEG_3318 | - | 1e-09 | 24.58% (354) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 1e-06 | 41.18% (68) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 5e-16 | 27.86% (384) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv0575c | - | 1e-06 | 41.18% (68) | hypothetical protein Rv0575c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2237c | - | 9e-15 | 27.90% (362) | hypothetical protein MAB_2237c |
| M. marinum M | MMAR_4944 | - | 7e-14 | 24.80% (379) | oxidoreductase |
| M. avium 104 | MAV_4429 | - | 2e-10 | 24.46% (372) | FAD binding domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0460 | - | 3e-10 | 24.87% (193) | hypothetical protein MUL_0460 |
| M. vanbaalenii PYR-1 | Mvan_5278 | - | 2e-12 | 24.93% (381) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0590c|M.bovis_AF2122/97 -------MKVAISGAGVAGAALAHWLQRTGHTPTVIERA-PKFRTGGYMI
Rv0575c|M.tuberculosis_H37Rv -------MKVAISGAGVAGAALAHWLQRTGHTPTVIERA-PKFRTGGYMI
MMAR_4944|M.marinum_M -------MKAVIIGAGIGGMSAAIALRQIGIDTEVYERV-TENKPVGAAI
Mvan_5278|M.vanbaalenii_PYR-1 -------MKVVIVGAGMGGMSAAIALRQIGIDTVVYERV-TENKPVGAAI
MUL_0460|M.ulcerans_Agy99 -------MKAVIIGAGIGGMSAAIALRQIGIDTEVYERV-TENKPVGAAI
Mflv_2621|M.gilvum_PYR-GCK -----MSARISVIGAGISGLAAAVALERAGHHVSVIEQR-TDTG-AGSGI
MAV_4429|M.avium_104 MVGDARPLRVLVVGAGVAGISVARGLLRDGHDVTVFERR-PRLAAAGGAV
MAB_2237c|M.abscessus_ATCC_199 --MSTDKTSIVVAGAGIGGLASALTLHAAGFEVVVLESA-REVKPLGVGI
MSMEG_6489|M.smegmatis_MC2_155 -MTDYSQARAVVVGGSIGGLTTALLLRDSGFHVDVFERTPTALDGRGSGI
: *..:.* : * * * * * * :
Mb0590c|M.bovis_AF2122/97 DFWGVGYQVAKRMGITDQIAAAGYHMEHVRSVG-PTGKVKADLGVDVFRR
Rv0575c|M.tuberculosis_H37Rv DFWGVGYQVAKRMGITDQIAAAGYHMEHVRSVG-PTGKVKADLGVDVFRR
MMAR_4944|M.marinum_M SVWSNGVKCLNYLGLEQQTARLGGIVETMSYAEAHSGETMCRISMQPLIE
Mvan_5278|M.vanbaalenii_PYR-1 SVWSNGVKCLNYLGLQEETAELGGKVETMSYVDGHTGDTMCRFSMHPLIE
MUL_0460|M.ulcerans_Agy99 SVWSNGVKCLNYLGLDQQTARLGGIVETMSYAEAHSGETMCRISMQPLIE
Mflv_2621|M.gilvum_PYR-GCK SLWPNALAALDQIGLGDSVRDAGGRVTAG-AIRWRDGTWVRRPSVRRIVD
MAV_4429|M.avium_104 TVWSNGETVLRQLGVEMDG--AGRQLSSVGAVT-STGRPLATLDVTAMAR
MAB_2237c|M.abscessus_ATCC_199 NMLPHAVGVLTELGLGERLTRMGIATTEIRFCDKHGTVLFTEP--RGLAG
MSMEG_6489|M.smegmatis_MC2_155 VLQPDTVRWFQER----SSQDLGDLQTATRFVQYLDRS-------GDVVH
. * .
Mb0590c|M.bovis_AF2122/97 MVGDDFTSLPRGDLAAAIYTTIED-QVETIFDDSIATIDEHRD--GVRLT
Rv0575c|M.tuberculosis_H37Rv MVGDDFTSLPRGDLAAAIYTTIED-QVETIFDDSIATIDEHRD--GVRLT
MMAR_4944|M.marinum_M QVGQRPYPIARAELQQMLMEAYG--IDEIHFGMKMVEVANRDG--AATAT
Mvan_5278|M.vanbaalenii_PYR-1 QVGQRPYPIARAELQLMLMKAYG--IDDINFGMKMVGVENDTAGSAAKAT
MUL_0460|M.ulcerans_Agy99 QVGQRPYPIARAELQQMLMEAYG--IDDIHFGMKMVEVANQDG--AATAT
Mflv_2621|M.gilvum_PYR-GCK ALGEPLVVVRRSRLTDILREALP--AGTVRTGLAATRVSVGAS--SVRIT
MAV_4429|M.avium_104 RLGAPVRMVPRRVLLERLLDGFP--TGRIHCDRRAVALATSRD--GVSVE
MAB_2237c|M.abscessus_ATCC_199 DYPHPQISVHRGRLQLMLLDAVRKRIGPQAVRTASRVLGFESDEAGVRVR
MSMEG_6489|M.smegmatis_MC2_155 REPATWTYTSWGTFYRALLADFG----TEHYHYGEYACGFDQDEAEAVVR
: : .
Mb0590c|M.bovis_AF2122/97 FERTAPRDFDLVIGADGLHSNVRRLVFG--PERDFEHYLGCKVAACVVDG
Rv0575c|M.tuberculosis_H37Rv FERTAPRDFDLVIGADGLHSNVRRLVFG--PERDFEHYLGCKVAACVVDG
MMAR_4944|M.marinum_M FADGTIASADILIGADGANSITREYVLGGPVTRRYAGYVNYNGLVEVDEA
Mvan_5278|M.vanbaalenii_PYR-1 FADGTTVSADVIIGADGAGSITREYVLGGPVSRRYAGYVNYNGLVSTDDA
MUL_0460|M.ulcerans_Agy99 FTDGTIASADILIGADGANSITREYVLGGPVTRRYAGYVNYNGLVEVDEA
Mflv_2621|M.gilvum_PYR-GCK LSDGEVRESDAVVGADGVNSVLARTLNG-PLRTRYVGYTAWRGIAAHPLD
MAV_4429|M.avium_104 FTDGTVAEGDVLIGADGLHSMVREWVGAR--HAKATGWCSWQGLVSLPEI
MAB_2237c|M.abscessus_ATCC_199 TATG-DIEAAVLVGADGVNSAIRAQLHP-ADRLHWSGVRMWRGASDVGPF
MSMEG_6489|M.smegmatis_MC2_155 FVSGRTAAADLVVFADGITSAARERFDP-DATLRYAGYIGWRGTVALSAL
:: *** * . .
Mb0590c|M.bovis_AF2122/97 YRPRDE---RSYVLYNTVDRQLARFALR-------GDRTMFLFVFRAEHD
Rv0575c|M.tuberculosis_H37Rv YRPRDE---RSYVLYNTVDRQLARFALR-------GDRTMFLFVFRAEHD
MMAR_4944|M.marinum_M ISPAN-----EWTMYVGDGKRVSAMPVA-------DDR-FYFFFDVVEPE
Mvan_5278|M.vanbaalenii_PYR-1 IGPAT-----EWTTYVGDGKRVSVMPVS-------DDR-FYFFFDVVEPQ
MUL_0460|M.ulcerans_Agy99 ISPAN-----EWTMYVGDGKRVSAMPPT-------TPRPASGRADARRWK
Mflv_2621|M.gilvum_PYR-GCK PELGG--------ETLGPGTQVGHVPLG-------PDHTYWFATERTAEG
MAV_4429|M.avium_104 AESDA------ALMMIGGSGNLGLWPAG-------GAEVQWWFDLPWS--
MAB_2237c|M.abscessus_ATCC_199 LTGKT-----MVVAHDDTDHELIAYPIS-------DRTVNWVALARTNPA
MSMEG_6489|M.smegmatis_MC2_155 SEPTRNTLRDAITYDVVPHSHITMYPIPGEDGLGESQRLMNYVWYRNVPA
.: .
Mb0590c|M.bovis_AF2122/97 ----------------NPGVAP---KDELRDQFGDVGWESRDILAALDDV
Rv0575c|M.tuberculosis_H37Rv ----------------NPGVAP---KDELRDQFGDVGWESRDILAALDDV
MMAR_4944|M.marinum_M ----------------GLPFEKGTAREVLREQFAGWAPGVQALIDKLDPT
Mvan_5278|M.vanbaalenii_PYR-1 ----------------GSPYEEGRVREVLRAHFAGWTPGVQTLIDTLDPL
MUL_0460|M.ulcerans_Agy99 ----------------TRWHCNGRSRTTPPTLRPRWPP--------IRPA
Mflv_2621|M.gilvum_PYR-GCK ----------------GS--APGGEHAYLTAKVADWADPIPRLVATTDPG
MAV_4429|M.avium_104 ----------------TGFVRPQHPIETIRSHFAGWSEPVDRVLAILTDE
MAB_2237c|M.abscessus_ATCC_199 G-----------ELPAGARWNDPATADEVLDHFPGWDFGWLDLDKMIRGA
MSMEG_6489|M.smegmatis_MC2_155 GPELTEMLIDKRGFGGSVSVHPGQVQDRYVDAIRADAAELFAPAVAETVV
Mb0590c|M.bovis_AF2122/97 EDLYFDVVSQ--IRMDRWSRGRVLLIGDAAGCISLLGGEGTGLAITEAYV
Rv0575c|M.tuberculosis_H37Rv EDLYFDVVSQ--IRMDRWSRGRVLLIGDAAGCISLLGGEGTGLAITEAYV
MMAR_4944|M.marinum_M TTNRVEILDL--DPFHTWVKGRVAVLGDAAHNTTPDIGQGGCSAMEDAVA
Mvan_5278|M.vanbaalenii_PYR-1 ATNRVEILDL--DPFHTWVKGRVAVLGDAAHNTTPDIGQGGCSAMEDAIA
MUL_0460|M.ulcerans_Agy99 APNGPAIWYC--GPVS------------AATSSTP---------------
Mflv_2621|M.gilvum_PYR-GCK DLLRNDLYDR--ARAARWSDGRAVLIGDAAHPMRPHLGQGGCQGIEDAAI
MAV_4429|M.avium_104 DLAASPFPHFR-HPIPPPGRGRVTLLGDAAHTMPPTLAQGTNQALLDTMV
MAB_2237c|M.abscessus_ATCC_199 EYVVEYPMVDR-DPLPHWGRDRVTLLGDAAHPMYPLGANGGSQSVVDARA
MSMEG_6489|M.smegmatis_MC2_155 RTEQPYLQVLSDVRSTRMAMGRVALIGDAACASRPHAAAGTAKAAADAWT
**
Mb0590c|M.bovis_AF2122/97 LAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFRHPN-----
Rv0575c|M.tuberculosis_H37Rv LAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFATRTRF---
MMAR_4944|M.marinum_M LQWALKDNPTDVAAALAAYQASRTERAGDLVLRARKRCDVIHAKDPD---
Mvan_5278|M.vanbaalenii_PYR-1 LQWAFKDHPDDVHAALAAYQSARTERAADLVLRARKRCDVTHAKDPQ---
MUL_0460|M.ulcerans_Agy99 ----------------------RTPIPPQPGMRS---CETNTAP------
Mflv_2621|M.gilvum_PYR-GCK LAR-FLELADDVPTAFERFEAFRKPRVGMLVREAQTLGRIVNVRPAV---
MAV_4429|M.avium_104 LCQALADFGRGTPGGQADVANALRWYEKTRRRRVRAVSWVASLPVSHGEA
MAB_2237c|M.abscessus_ATCC_199 LAVALAGHPGDPAGGLSAYESQRIAATHEVVLANRAMLRSWGDQSPE---
MSMEG_6489|M.smegmatis_MC2_155 LAGALAASDGDIAAALRKWEPAQLQLSDSLLRRVVDMGDRSQFHNTWWP-
Mb0590c|M.bovis_AF2122/97 -----PIRPVVSQRCDAHDELRPAGDAVRRQRA-----------------
Rv0575c|M.tuberculosis_H37Rv ---GLWFRNVAMRTMNFGPLATLFAGSVRDDFELPDYTW-----------
MMAR_4944|M.marinum_M ---TTAAWYEELRNEDGTNIIRGLVANIMGGPLTPLS-------------
Mvan_5278|M.vanbaalenii_PYR-1 ---VTSRWYDELRNEDGTNIIRGIVGNIVGGPLTPVTAATEG--------
MUL_0460|M.ulcerans_Agy99 -----------------TSFAGSSPTSWVGRSLR----------------
Mflv_2621|M.gilvum_PYR-GCK ---LSGLAGRATALIPERMVTAHLAWIAAGSAFVLPTAADLAR-------
MAV_4429|M.avium_104 VLRPAALVSDRLQAAALTMFLRWTSHRRMSDHINRSVGEAINRSLGEAPK
MAB_2237c|M.abscessus_ATCC_199 -------------------GLRKTAQSYRRRTRA----------------
MSMEG_6489|M.smegmatis_MC2_155 -------------------GDPDLRFGLYGPGH-----------------
Mb0590c|M.bovis_AF2122/97 -----
Rv0575c|M.tuberculosis_H37Rv -----
MMAR_4944|M.marinum_M -----
Mvan_5278|M.vanbaalenii_PYR-1 -----
MUL_0460|M.ulcerans_Agy99 -----
Mflv_2621|M.gilvum_PYR-GCK -----
MAV_4429|M.avium_104 IPSRR
MAB_2237c|M.abscessus_ATCC_199 -----
MSMEG_6489|M.smegmatis_MC2_155 -----