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VRRYLAATFSALTIRDYRRYALGQTISVSGTWMQKLTQAWLVLELTDSPLLLGVTVAGQQLPTLLFTTLA GVLADRYSKRTILLWTALGGMLPALVLGVLVWIDVVNIWIVLAAAVAQGFADAVDKPARLTFVNDIATPE TLANAVTLNSIIQNSGKIAGPAVAGVLISAVGVSASFFLNAASYLPVVIALLLIRPHAPVITGNVSAKGH LGETLRYVSARPHIAAALVLMAVSGLLAFNWNVLLPTLARDTFGGDARVVGFAFTSMGVGAVFGGLALAG VLRGTSKWLILNGCVLGAALALTGLMPTVTIAYALLFVVGAASVTFRSTATTLLQLYSDPGVRGRIISLL VLATNGTTPVGGPMIGWICTHANPRVACLVGGLGTVAAALAHWAYLRKAGTRKDPIPL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6390 | - | - | 100% (408) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_0357 | - | 2e-26 | 26.90% (394) | transmembrane transport protein |
| M. smegmatis MC2 155 | MSMEG_5674 | - | 7e-25 | 25.12% (430) | membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 6e-13 | 24.27% (375) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_5163 | - | 2e-32 | 28.22% (404) | protein of unknown function DUF894, DitE |
| M. tuberculosis H37Rv | Rv1258c | - | 6e-13 | 24.27% (375) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0880 | - | 1e-61 | 36.13% (393) | hypothetical protein MAB_0880 |
| M. marinum M | MMAR_4182 | - | 2e-14 | 24.79% (359) | hypothetical protein MMAR_4182 |
| M. avium 104 | MAV_1406 | - | 3e-12 | 22.28% (395) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_1317 | - | 1e-28 | 27.63% (380) | transmembrane transport protein |
| M. ulcerans Agy99 | MUL_0051 | - | 1e-13 | 22.84% (324) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_1167 | - | 1e-28 | 26.93% (401) | protein of unknown function DUF894, DitE |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6390|M.smegmatis_MC2_155 -MRRYLAATFSAL-TIRDYRRYALGQTISVSGTWMQKLTQA--WLVLELT
MAB_0880|M.abscessus_ATCC_1997 --MADRGGIFVSL-RTRNYRLWISGQMVSLIGTWMQRVAQD--WLVLDLS
Mflv_5163|M.gilvum_PYR-GCK MTSPVSTSTWAPL-QSPVFRALWIAQFVSNLGTWMQTVGAQ--WMLVDDP
Mvan_1167|M.vanbaalenii_PYR-1 MALAGSTSTWAPL-GSPIFRALWIAQFVSNLGTWMQTVGAQ--WMLVDDP
TH_1317|M.thermoresistible__bu ---------------------LWIAQFVSNLGTWMQTVGAQ--WMLVSTP
Mb1288c|M.bovis_AF2122/97 ---------MRNS-NRGPAFLILFATLMAAAGDGVSIVAFP--WLVLQRE
Rv1258c|M.tuberculosis_H37Rv ---------MRNS-NRGPAFLILFATLMAAAGDGVSIVAFP--WLVLQRE
MMAR_4182|M.marinum_M ---------MRNS-SRGPAFLILFATLAACAGNGISIVAFP--WLVLERE
MAV_1406|M.avium_104 --------------------MILFATLLATAGTGISIVAFP--WLALQHR
MUL_0051|M.ulcerans_Agy99 MHASAPVELWRSVRSLPDFWRLLQVRIASQFGDGLFQAGLAGALLFNPDR
: * : :
MSMEG_6390|M.smegmatis_MC2_155 DS-PLLLGVTVAGQQLPTLLFTTLAGVLADRYSKRTILLWTALGGMLPAL
MAB_0880|M.abscessus_ATCC_1997 HGNAFLLGVVMALQFGPTLLLSVWGGMLADRYDKRRMLMLTQALMALFAL
Mflv_5163|M.gilvum_PYR-GCK AAAVLVP-LVQTATTLPVMLLALPSGVLADLVDRRRLLIATQGAMAAGVG
Mvan_1167|M.vanbaalenii_PYR-1 RAAVLVP-LVQTATTLPVMLLALPSGVLADLIDRRRLLIATQGAMAAGVG
TH_1317|M.thermoresistible__bu AAEVLVP-LVQTATTLPIMLLSLPSGVVADLVDRRRLLLATQSMMAAAVA
Mb1288c|M.bovis_AF2122/97 GSAGQAS-IVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVA
Rv1258c|M.tuberculosis_H37Rv GSAGQAS-IVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVA
MMAR_4182|M.marinum_M GSAGQAS-IVAGAITLPLLFSTLVAGTAVDYFGRRPVSMVSDALSGSAVA
MAV_1406|M.avium_104 HSATDAS-IVAAAMTLPLVLATLIAGTAVDFFGRRRVSLVCDWLSGAAVT
MUL_0051|M.ulcerans_Agy99 AADPMAIARAFAVLFLPYSLLGPFAGALMDRWDRRLVIVGANIGRLILIA
. . * : .* * .:* : :
MSMEG_6390|M.smegmatis_MC2_155 VLGVLVWIDVVNIWIVLAAAVAQGFADAVDKP---ARLTFVNDIATPE--
MAB_0880|M.abscessus_ATCC_1997 TVGLLQVTGLVRIWHVMAVAFAMGCAAAIEAP---TRQSFTIEMVGPE--
Mflv_5163|M.gilvum_PYR-GCK LLATLTGAGLTTPTVLLTLLFVIGCGQALTAP---AWQAIQPDLVPSD--
Mvan_1167|M.vanbaalenii_PYR-1 LLAVLTGAGLTTPTVLLMLLFVIGCGQALTAP---AWQAIQPDLVPAH--
TH_1317|M.thermoresistible__bu ILAALTAAQLTTPTVLLILLFLIGCGQAFTAP---AWQAIQPELVPRE--
Mb1288c|M.bovis_AF2122/97 GVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGW
Rv1258c|M.tuberculosis_H37Rv GVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGW
MMAR_4182|M.marinum_M IVPLIAWAFGDDAVSVAVLAALGACSATFDPAGITARQSMLPEAAARAGW
MAV_1406|M.avium_104 AVPLTAWIFGAAAIDVAELAVLAFCAAAFDPAGMTARQSMLPEAAARAGW
MUL_0051|M.ulcerans_Agy99 GIGTILAFEAGDLLLLFVALLANGLARFVASGLSASLPHVVPREQVVTMN
: : . . : .
MSMEG_6390|M.smegmatis_MC2_155 TLANAVTLNSIIQNSGKIAGP----AVAGVLISAVGVSASFFLNAASYLP
MAB_0880|M.abscessus_ATCC_1997 HLPNAVGLNSMVFNLAGIIGP----ATSGVLIGLIGTGWVFLLNFVSFIA
Mflv_5163|M.gilvum_PYR-GCK QIPAAAALGSMSMNGARAIGP----AIAGALVSLTGPTIVFALNAVSFVG
Mvan_1167|M.vanbaalenii_PYR-1 QIPAAAALGSMSMNGARAIGP----AIAGALVSLTGPTLVFALNAVSFIG
TH_1317|M.thermoresistible__bu QIPAAAALTSMSLNAARAVGP----AVAGVLVAISGPTLVFTLNAVSFAG
Mb1288c|M.bovis_AF2122/97 SLDRINGAYEAILNLAFIVGP----AIGGLMIATVGGITTMWITATAFGL
Rv1258c|M.tuberculosis_H37Rv SLDRINGAYEAILNLAFIVGP----AIGGLMIATVGGITTMWITATAFGL
MMAR_4182|M.marinum_M SLDRINSSYEAILNLAFVVGP----GIGGLMIATVGGITTMWITAGAFGL
MAV_1406|M.avium_104 SLDRTNSSYEAMLNLAFIVGP----GLGGLLIATLGGINTMWVTAGCFAL
MUL_0051|M.ulcerans_Agy99 SVATASGAVAAFVGANFMLLPRWLAGGGDHGAAAVIFTAMIPVAISLLLA
: . * . .. . : :
MSMEG_6390|M.smegmatis_MC2_155 VVIALLLIRPHAPVITG-NVSAKGHLG---ETLRYVSARPHIAAALVLMA
MAB_0880|M.abscessus_ATCC_1997 VGIALWRMRPGELHSSEPIPAAKGQLR---QGFSYVWRRRDLFMIMLTVF
Mflv_5163|M.gilvum_PYR-GCK IVLVLMWWRRPPVRSDYPPERALAALS---AGGRYIRSSPIVRRILLRTV
Mvan_1167|M.vanbaalenii_PYR-1 IVLVLISWRRPAVQRDFPPERALAALS---AGGRYIRSSPIVRRILLRTV
TH_1317|M.thermoresistible__bu IVVVLLLWKRSSAEQTLAAERPLAALQ---AGHRYVRSSPVVRRILFRAA
Mb1288c|M.bovis_AF2122/97 SILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDL
Rv1258c|M.tuberculosis_H37Rv SILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDL
MMAR_4182|M.marinum_M SLLAIGALRLEGAGRPHHETRPDGLVSGVTQGLRFVWNLRVLRALALIDL
MAV_1406|M.avium_104 SFLAIGALRLEGAGKPPRATRPVGLVTGIAEGVRFVWNLRVLRTLGLIDL
MUL_0051|M.ulcerans_Agy99 LRFAPRVLGPDDTKRAIHGSAVYAVITGWMHGVRTVVQIPTVAAALSGLA
.. . : : :
MSMEG_6390|M.smegmatis_MC2_155 VSGLLAFNWNVLLPTLARDTFGGDARVVG---FAFTSMGVGAVFGG--LA
MAB_0880|M.abscessus_ATCC_1997 LVSTFGLNFSLTLAVLARETFGRGAESYG---LLSTALAIGTLLGAT-FA
Mflv_5163|M.gilvum_PYR-GCK LFIAPGSAVWGLLPVIARDQLGLGSAGYG---ALLGALGVGAVLGAFALS
Mvan_1167|M.vanbaalenii_PYR-1 LFIAPASALWGLLPVIAANQLGLGSAGYG---LLLGALGAGAVLGAFVLS
TH_1317|M.thermoresistible__bu LFILPASALWGLLPVVASSGLGLSSSGYG---LMLGALGAGAVLGALTLS
Mb1288c|M.bovis_AF2122/97 TVTALYLPMESVLFPKYFTDH-QQPVQLG---WALMAIAGGGLVGALGYA
Rv1258c|M.tuberculosis_H37Rv TVTALYLPMESVLFPKYFTDH-QQPVQLG---WALMAIAGGGLVGALGYA
MMAR_4182|M.marinum_M TVTALYLPMESVLFPTYFSDR-QQPAQLG---SVLVALSLGSLVGALGYG
MAV_1406|M.avium_104 AVTALYLPMESVLFPKYFADQ-HQPAQLG---WALMALALGGVAGALGYA
MUL_0051|M.ulcerans_Agy99 AHRMVVGVNSLLILLLVHHMRDVDVEGLGTALLFFAATGLGAFLANVLTP
: * : . * . .
MSMEG_6390|M.smegmatis_MC2_155 LAGVLRGTSKWLILNGCVLGAALALTGLMPTVTIAYALLFVVGAASVTFR
MAB_0880|M.abscessus_ATCC_1997 ARRTKKVRMTLFYGAAMAFGLSEVVVSVMPTYLSVALALVPAGLLALTFT
Mflv_5163|M.gilvum_PYR-GCK RLRARFGQNKLLIAGAAGFGMATAVLALVHNVALVAAALVVGGAAWLLTL
Mvan_1167|M.vanbaalenii_PYR-1 GLRTRFGQNVLLTAGAAGFAVATAVLALVPDFAAVLAALVVGGGAWLLSL
TH_1317|M.thermoresistible__bu AWQSAFRQNTLLALAAVGFAAATAVAVLVPDVVVVLIGLTVGGMSWLLAL
Mb1288c|M.bovis_AF2122/97 VLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQ
Rv1258c|M.tuberculosis_H37Rv VLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQ
MMAR_4182|M.marinum_M MLSNYVSRRTIMLTAVLTLGAATTGIALLPPLPVILVLCALIGVVYGPIQ
MAV_1406|M.avium_104 VLSARLRRRTAVLTATLTFGATTAGIAVLPPLPVILGLCAVTGVVYGPIQ
MUL_0051|M.ulcerans_Agy99 GLIRRWGR-YATTNGALAAAAVTQLAGAGLLLPVMVVCGFLLGVAGQVVK
. *
MSMEG_6390|M.smegmatis_MC2_155 STATTLLQLYSDPGVRGRIISLLVLATNGTTPVGGPMIGWICTHANPRVA
MAB_0880|M.abscessus_ATCC_1997 TSAMNIIQLSVDSQLRGRVMGIYMVAFLGGTPLGSPLVGWLADLHGGRMP
Mflv_5163|M.gilvum_PYR-GCK STLNASMQLSLPSWVRARGLSVYQLIFMGGQAVGSLLWGLLAGGTSSVIS
Mvan_1167|M.vanbaalenii_PYR-1 STLNASMQLSLPAWVRARGLSVYQLIFMGGQAIGSLLWGLLAGATNSVTS
TH_1317|M.thermoresistible__bu ATLNASMQLSLPAWVRARGLSVYLLIFMGGQALGSTMWGLVAGSTSTVVA
Mb1288c|M.bovis_AF2122/97 PIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHAT
Rv1258c|M.tuberculosis_H37Rv PIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHAT
MMAR_4182|M.marinum_M PIYNYVMQTRAPHYLRGRVVGVMTSLAYAAGPLGLLLAGPVADAAGLKVA
MAV_1406|M.avium_104 PIYNFVMQTRAPHHLRGRVVGVMAGLTYAAGPLGLLVAGPLADAAGLKAT
MUL_0051|M.ulcerans_Agy99 LCADSAMQIDVDGALRGHVFAVQDALFWVSYIVSVTVAAALIPDDGRAPV
:* :*.: ..: :. : . : .
MSMEG_6390|M.smegmatis_MC2_155 CLVGGLGTVAAALAHWAYLR------------------------------
MAB_0880|M.abscessus_ATCC_1997 LLVGGLVSAAAGLVCATYLHRH---------------PCPVVAGEVPEAD
Mflv_5163|M.gilvum_PYR-GCK LLVSAGLLIFCGLSLWWWPLHAGTGNLDLTPSSHWPEPTLLFEPEPLDGP
Mvan_1167|M.vanbaalenii_PYR-1 LLVSAGLLVVCALSSLWWPLHAGTGNLDLTPSSHWPEPTLVFEPEPLDGP
TH_1317|M.thermoresistible__bu MLISAGLLVVSGLSAWWWPLHPQTGQLDVSPSAHWPEPALVFEPEPRDGP
Mb1288c|M.bovis_AF2122/97 FLALALPIVCTGLVAIRLPALR----------------------------
Rv1258c|M.tuberculosis_H37Rv FLALALPIVCTGLVAIRLPALR----------------------------
MMAR_4182|M.marinum_M FFALALPIAITGLMCIRLPSLR----------------------------
MAV_1406|M.avium_104 FLTLAVPILAIGVVACGLPSLR----------------------------
MUL_0051|M.ulcerans_Agy99 FVLVGSLIYLLGLCVHSIVGRR----------------------------
. . .:
MSMEG_6390|M.smegmatis_MC2_155 -------KAGTRKDPIPL--------------------------------
MAB_0880|M.abscessus_ATCC_1997 DMVPPAPAATPVCEPTPLARRS----------------------------
Mflv_5163|M.gilvum_PYR-GCK VLVITAYRVLPENEEPFMSAMARLGRSRQRTGASMWQLFRSIEQESTFVE
Mvan_1167|M.vanbaalenii_PYR-1 VLVLTSYCVPAHNEGAFLAAMAVLGRSRQRTGASQWRLFRSVEQESTFVE
TH_1317|M.thermoresistible__bu VLVLSTYRVAPEDEPAFLVAMQRQARSRQRTGAALWRLYRHLEREHTFVE
Mb1288c|M.bovis_AF2122/97 -----ELDLAPQADIDRPVGSAQ---------------------------
Rv1258c|M.tuberculosis_H37Rv -----ELDLAPQADIDRPVGSAQ---------------------------
MMAR_4182|M.marinum_M -----ELDHAPTQDISETSLL-----------------------------
MAV_1406|M.avium_104 -----ELDRAPQFADDPGA-------------------------------
MUL_0051|M.ulcerans_Agy99 -------SSASNVEGC----------------------------------
.
MSMEG_6390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0880|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_5163|M.gilvum_PYR-GCK TFIVRSWGEHMHQHYTRLTGQDQLIEQDVERYTEGEAVAEHYLAVRDAR-
Mvan_1167|M.vanbaalenii_PYR-1 TFIVRSWGEHMHQHYTRLTGQDQLIEQNVEQYTDGTPVSQHYLAVRDV--
TH_1317|M.thermoresistible__bu AFLVRSWDEHLRQHHVRLTLVDQRVEEEVRRYAEGPPLVEHLIAVNFDEI
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4182|M.marinum_M --------------------------------------------------
MAV_1406|M.avium_104 --------------------------------------------------
MUL_0051|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6390|M.smegmatis_MC2_155 -----
MAB_0880|M.abscessus_ATCC_1997 -----
Mflv_5163|M.gilvum_PYR-GCK -----
Mvan_1167|M.vanbaalenii_PYR-1 -----
TH_1317|M.thermoresistible__bu TRRGV
Mb1288c|M.bovis_AF2122/97 -----
Rv1258c|M.tuberculosis_H37Rv -----
MMAR_4182|M.marinum_M -----
MAV_1406|M.avium_104 -----
MUL_0051|M.ulcerans_Agy99 -----