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SSEEPRRRGRRRSEESRRAILAAAFDLVAAEGQDFTIEGIAARAGVSKQTIYRWWPTKGDILLESLAAQA DAQISVSDHGSYQEDLLHFLNQTFKLLRPHGVRSALRSLMAEAQQNPDLLLRFREGFLERRRAALFQIIS RAESRGDLPPEVRGGLIGDIVFGVIWYRMLATEQLLSSIEARNLAHLLASTTRRPADRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5567 | - | - | 100% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 2e-25 | 36.00% (175) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 1e-15 | 28.49% (186) | putative TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 5e-12 | 26.80% (153) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_3683 | - | 2e-19 | 33.54% (164) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 5e-12 | 26.80% (153) | regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 2e-06 | 40.68% (59) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 1e-24 | 35.56% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 2e-13 | 31.90% (163) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5267 | - | 2e-17 | 31.15% (183) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 4e-12 | 28.57% (175) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 8e-13 | 31.29% (163) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | 5e-19 | 32.56% (172) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 -----MVGAVT-QIADRPTDP-----SPWSPRETELLAVTLRLLQEHGYD
Rv1556|M.tuberculosis_H37Rv -----MVGAVT-QIADRPTDP-----SPWSPRETELLAVTLRLLQEHGYD
MAB_3462c|M.abscessus_ATCC_199 -----MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDLLVARGYA
Mvan_5223|M.vanbaalenii_PYR-1 -----MVEAGSAARRGRPR---------SEAARSAVLTAAAELALEGGPA
MMAR_0340|M.marinum_M -----MVADFG-----RPRDP---------RIDGAVLRATVELLAETGYA
MUL_4780|M.ulcerans_Agy99 -----MVADFG-----RPRDP---------RIDGAVLRATVELLAETGYA
MSMEG_5567|M.smegmatis_MC2_155 ------MSSEEPRRRGRRRSE---------ESRRAILAAAFDLVAAEG-Q
TH_4110|M.thermoresistible__bu VTATDAAATGRAAARGRPRDP---------ALDSAILDAALEIFVEQGIS
Mflv_3683|M.gilvum_PYR-GCK -------------MMTRRRGA---------ELDAAIRSAVLDLLAGHGPE
MAV_5267|M.avium_104 -----MPTDPNGPAAPRRRSE---------KSRTAIVTATRELLLERGFD
MLBr_00316|M.leprae_Br4923 ---MSVPRSGLSVQMAQPARPLR---ADAARNRARILGVAYEAFATEG-L
: .. *
Mb1581|M.bovis_AF2122/97 RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPN-----
Rv1556|M.tuberculosis_H37Rv RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPN-----
MAB_3462c|M.abscessus_ATCC_199 GVTMEGIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQLDPPD-----
Mvan_5223|M.vanbaalenii_PYR-1 AATVEAIAKRAHVSRTTIYKWWPSAASIVLEGLLDAVRASITRPS-----
MMAR_0340|M.marinum_M GLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPD-----
MUL_4780|M.ulcerans_Agy99 GLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPD-----
MSMEG_5567|M.smegmatis_MC2_155 DFTIEGIAARAGVSKQTIYRWWPTKGDILLESLAAQADAQISVSD-----
TH_4110|M.thermoresistible__bu ALSIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEAS
Mflv_3683|M.gilvum_PYR-GCK AVTMDAVAVAAGTSKPVLYRRWPDRRALLRDTLMAVASTSFPRPD-----
MAV_5267|M.avium_104 GLTIEAVAARAGVGKQTIYRWWPTRPALVADVMLEDADRLLASVEH----
MLBr_00316|M.leprae_Br4923 SVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLK-
:. :* * .. .:*: :. : .
Mb1581|M.bovis_AF2122/97 TGNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFV
Rv1556|M.tuberculosis_H37Rv TGNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFV
MAB_3462c|M.abscessus_ATCC_199 LGGLEADLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLADDFRGRYL
Mvan_5223|M.vanbaalenii_PYR-1 GSTSVQALVHHVSSLNAILADPAVGPLLRNVIAASTSDPAIERAVLDQWI
MMAR_0340|M.marinum_M TGSPVDDLREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFG
MUL_4780|M.ulcerans_Agy99 TGSPVDDLREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFG
MSMEG_5567|M.smegmatis_MC2_155 HGSYQEDLLHFLNQTFKLLRPHGVRSALRSLMAEAQQNPDLLLRFREGFL
TH_4110|M.thermoresistible__bu VSDPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYI
Mflv_3683|M.gilvum_PYR-GCK TGTFRGDLLAVLRAWAQLFTGDTG-PLMRSVIVAVASDPDLESTFRSDVL
MAV_5267|M.avium_104 SGDLAADLVGWVGKLVTSLTTPRGSAMLRTLTVACMEHEDTAVKLRAGFS
MLBr_00316|M.leprae_Br4923 SAGPGEALFTYLRSLVLHWGATDR-GLVDALAGAGGID---ILGVAPDAE
. : : .
Mb1581|M.bovis_AF2122/97 DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIP----NR
Rv1556|M.tuberculosis_H37Rv DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIP----NR
MAB_3462c|M.abscessus_ATCC_199 REQQARDQIPIARAVARGELPADVDVAHVAEQLVAPLYYRVIVT----GE
Mvan_5223|M.vanbaalenii_PYR-1 APRRAAVAVTLREAVDRGELPGDVDIEVAVDALVSPPYYRLVLG----MP
MMAR_0340|M.marinum_M EIFGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEP
MUL_4780|M.ulcerans_Agy99 EIFGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEP
MSMEG_5567|M.smegmatis_MC2_155 ERRRAALFQIISRAESRGDLPPEVRGGLIGDIVFGVIWYRMLATEQLLSS
TH_4110|M.thermoresistible__bu LPRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQP-----E
Mflv_3683|M.gilvum_PYR-GCK GMRKAEMTTLIGRAVERGEVRPDVPVELVRELGQSVLWHRLLIT----GD
MAV_5267|M.avium_104 APLHDSVRARLLAEG-----VDAATAESAADAIVGGVVYPILSG----AQ
MLBr_00316|M.leprae_Br4923 DAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYNS------
: . . .
Mb1581|M.bovis_AF2122/97 PPTQDTVQALVDDVILPSLTRSTG-
Rv1556|M.tuberculosis_H37Rv PPTQDTVQALVDDVILPSLTRSTG-
MAB_3462c|M.abscessus_ATCC_199 TVDAAFVDRIVEDFLRRRE------
Mvan_5223|M.vanbaalenii_PYR-1 PLAAEAVDRLVETVWSGCRH-----
MMAR_0340|M.marinum_M GVGDAWIDRTTTLLLKGIRKGTPQ-
MUL_4780|M.ulcerans_Agy99 GVGDAWIDRTTTLLLKGIRKGTPQ-
MSMEG_5567|M.smegmatis_MC2_155 IEARNLAHLLASTTRRPADRR----
TH_4110|M.thermoresistible__bu PPSARQLRCYLEVAYRQVGLLP---
Mflv_3683|M.gilvum_PYR-GCK PITDELVTQLVDEVLIPVTRPYYDQ
MAV_5267|M.avium_104 RYSRRRAEHTTRLIVAALTAG----
MLBr_00316|M.leprae_Br4923 ----ALAERVTDVVVDGLRAAR---