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MVADFGRPRDPRIDGAVLRATVELLAETGYAGLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAA TAVPDTGSPVDDLREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGLTTWLDNAA ARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAWIDRTTTLLLKGIRKGTPQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4780 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2482 | - | 4e-40 | 42.63% (190) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_1934 | - | 7e-12 | 30.57% (157) | regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 6e-42 | 42.49% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4384 | - | 8e-63 | 63.73% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 6e-42 | 42.49% (193) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0260 | - | 9e-21 | 39.41% (170) | transcriptional regulator TetR |
| M. marinum M | MMAR_0340 | - | 1e-110 | 99.50% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 8e-79 | 77.89% (190) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2043 | - | 3e-37 | 41.88% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0688 | - | 1e-41 | 44.56% (193) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 7e-61 | 62.77% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
Rv3167c|M.tuberculosis_H37Rv --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
MSMEG_2043|M.smegmatis_MC2_155 --------MKAEASPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYANL
TH_0688|M.thermoresistible__bu --------MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNL
MUL_4780|M.ulcerans_Agy99 -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MMAR_0340|M.marinum_M -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MAV_5165|M.avium_104 -------------------MDFGRPRDPRIDAAVLRATVELLAETGYPGL
Mflv_4384|M.gilvum_PYR-GCK MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVELLAESSYAEL
Mvan_1961|M.vanbaalenii_PYR-1 ---------------------MGRPRNRAIDDAVLRATVELISESSYAEL
MAB_0260|M.abscessus_ATCC_1997 ------------MSTEESSLGRGRRRSSDIDVKALAAARELLVEQGWEAT
** *. * * *: :*: : .:
Mb3192c|M.bovis_AF2122/97 SLAAVAERAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAAD
Rv3167c|M.tuberculosis_H37Rv SLAAVAERAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAAD
MSMEG_2043|M.smegmatis_MC2_155 TMAAVAERAQTTKTALYRRWSSKAELVHEAVFP-AVPTGLVAPAGDIAAD
TH_0688|M.thermoresistible__bu TMSAVAERAGTTKTALYRRWSSKPELVYAATAP-TDPVDTVESSDDVAGI
MUL_4780|M.ulcerans_Agy99 LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPDTGSPVDD
MMAR_0340|M.marinum_M LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPDTGSPVDD
MAV_5165|M.avium_104 LVSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFP-VGADTAIPDTGSTADD
Mflv_4384|M.gilvum_PYR-GCK SLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFP-LGADTAIPGSGSLEAD
Mvan_1961|M.vanbaalenii_PYR-1 SLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFP-VDATIEIPRTGSLHGD
MAB_0260|M.abscessus_ATCC_1997 TMVAIADRASVGKPALYRRWPSRAHLVFEAVFGWTAPTPEMSAAAGVTDW
: *:* ** . *.*:**** .:..**. *. . : .
Mb3192c|M.bovis_AF2122/97 IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-V
Rv3167c|M.tuberculosis_H37Rv IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-V
MSMEG_2043|M.smegmatis_MC2_155 VHAMIAAARDVFTSPVVRAALPGLIADVSADANLNARVMERFTGVFAA-V
TH_0688|M.thermoresistible__bu VRALIERNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVGSLVEA-L
MUL_4780|M.ulcerans_Agy99 LREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGL
MMAR_0340|M.marinum_M LREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEIFGHGL
MAV_5165|M.avium_104 LREMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGL
Mflv_4384|M.gilvum_PYR-GCK VREMTRRTLAVLSTPAALAALPGLVGEMASDPTLHTALLERFGDILVRGL
Mvan_1961|M.vanbaalenii_PYR-1 VREMLRRTLAVLSTPAARAALPGLVGEMASDPTLHAALLERFADVLVRDL
MAB_0260|M.abscessus_ATCC_1997 VRQSCSYTAELFERPDVIAAAPALLGQMRTDPELGQALWGSFGATGAGLL
:: . * . ** *.*: :: :*. * : . :
Mb3192c|M.bovis_AF2122/97 RMRLREAVD-RGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAW
Rv3167c|M.tuberculosis_H37Rv RMRLREAVD-RGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAW
MSMEG_2043|M.smegmatis_MC2_155 RERIVDGIA-RGEVHAAVSPDRLVEIIGGATMLRLLLVSDENLD---DEW
TH_0688|M.thermoresistible__bu RRRLAEAAG-RGEVQSGVDADRLTELIGGSVMFRMVLHPDEPIT---ERW
MUL_4780|M.ulcerans_Agy99 TTWLDNAAA-RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAW
MMAR_0340|M.marinum_M TTWLDNAAA-RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAW
MAV_5165|M.avium_104 ADWLAAAAA-RGEARPDVTAAELAETIAGVTLVALLTRPTELD----DAW
Mflv_4384|M.gilvum_PYR-GCK TEFLESAVR-RGDVRPDVTASDLAEAVAGMTLLALLTRGTAVD----EVW
Mvan_1961|M.vanbaalenii_PYR-1 NNYLDSAVR-RGEVRRGVTAVELAEAVTGMTLLALITRGANVD----DAW
MAB_0260|M.abscessus_ATCC_1997 SRVMRAQQPEIGQEEAQERANAIMFMIIGANMLARQLLPGEHA----EAV
: *: . . : : * :. :
Mb3192c|M.bovis_AF2122/97 VDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv VDQTTAIVVRGVHRAAPGGSVV
MSMEG_2043|M.smegmatis_MC2_155 VHQTAAIVIHGVTVGR------
TH_0688|M.thermoresistible__bu ADEVAAILIRGVTKEG------
MUL_4780|M.ulcerans_Agy99 IDRTTTLLLKGIRKGTPQ----
MMAR_0340|M.marinum_M IDRTTTLLLKGIRKGTPQ----
MAV_5165|M.avium_104 VDRTTRLLLKGISA--------
Mflv_4384|M.gilvum_PYR-GCK LDRTARLITKGISA--------
Mvan_1961|M.vanbaalenii_PYR-1 IERTAHLITKGISS--------
MAB_0260|M.abscessus_ATCC_1997 IKHLPELLTEPGESPGSVRPSG
.. . :: .