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VEAGSAARRGRPRSEAARSAVLTAAAELALEGGPAAATVEAIAKRAHVSRTTIYKWWPSAASIVLEGLLD AVRASITRPSGSTSVQALVHHVSSLNAILADPAVGPLLRNVIAASTSDPAIERAVLDQWIAPRRAAVAVT LREAVDRGELPGDVDIEVAVDALVSPPYYRLVLGMPPLAAEAVDRLVETVWSGCRH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | - | 100% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0778 | - | 9e-15 | 27.22% (180) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 3e-14 | 28.57% (182) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 3e-16 | 30.49% (164) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 8e-82 | 78.53% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 3e-16 | 30.49% (164) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 4e-05 | 27.59% (174) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4749c | - | 1e-27 | 33.87% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 2e-14 | 33.12% (154) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4057 | - | 2e-17 | 30.49% (164) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 2e-24 | 30.27% (185) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 7e-25 | 34.43% (183) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 6e-14 | 32.47% (154) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5223|M.vanbaalenii_PYR-1 -------MVEAGSAARRGRPRS----EAARSAVLTAAAELALEGGPAAAT
Mflv_1535|M.gilvum_PYR-GCK ------------MASRRGRPRS----EAVRSAVLTAAAELALAGGPAAAS
Mb3192c|M.bovis_AF2122/97 ---MKADLPSLDKAPGAGRPRD----PRIDSAILSATAELLVQIGYSNLS
Rv3167c|M.tuberculosis_H37Rv ---MKADLPSLDKAPGAGRPRD----PRIDSAILSATAELLVQIGYSNLS
MAV_4057|M.avium_104 ---MKADPSGLDKAPGAGRPRD----PRIDSAILSATAELLVQTGYSNIS
MMAR_0340|M.marinum_M ---MVAD---------FGRPRD----PRIDGAVLRATVELLAETGYAGLL
MUL_4780|M.ulcerans_Agy99 ---MVAD---------FGRPRD----PRIDGAVLRATVELLAETGYAGLL
MAB_4749c|M.abscessus_ATCC_199 ------MNGTRPRQPRRGRRPT----EEVREEVLQAAGELLFTEGMGGFT
MSMEG_5301|M.smegmatis_MC2_155 ------MT-TNPRR-GRGRRPA----QDVRRDVLAAVADLLFTEGMAGFT
TH_4110|M.thermoresistible__bu --VTATDAAATGRAAARGRPRD----PALDSAILDAALEIFVEQGISALS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
** :* .. : .
Mvan_5223|M.vanbaalenii_PYR-1 VEAIAKRAHVSRTTIYKWWPSAASIVLEGLLDA-VRASITRPSGSTSVQA
Mflv_1535|M.gilvum_PYR-GCK VEAIARRAEVSRTTIYKWWPSAPAIVLEGLLDS-VRDSITRPPGSTSVEA
Mb3192c|M.bovis_AF2122/97 LAAVAERAGTTKSALYRRWSSKAELVHEAAFPA-APTALQAAAG-DIAAD
Rv3167c|M.tuberculosis_H37Rv LAAVAERAGTTKSALYRRWSSKAELVHEAAFPA-APTALQAAAG-DIAAD
MAV_4057|M.avium_104 LAAVAERAGTTKSALYRRWSSKAELVHEAAFPT-APTALEAPAG-DIAAD
MMAR_0340|M.marinum_M VSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPI-DAATAVPDTG-SPVDD
MUL_4780|M.ulcerans_Agy99 VSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPI-DAATAVPDTG-SPVDD
MAB_4749c|M.abscessus_ATCC_199 IDKVAALSGASKMTIYKWWPSKGALALDGYFRK-VEPDLNFPDSGEIERD
MSMEG_5301|M.smegmatis_MC2_155 IDKVAARSGVSKVTIYKWWPSKGALALDGYFAK-VEPRLAFPDTGDIEAD
TH_4110|M.thermoresistible__bu IEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR-VSAELAWPTPAEASVS
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* : : ::* :.. : .
Mvan_5223|M.vanbaalenii_PYR-1 -----LVHHVSSLNAILADPAVGPLLRNVIAASTSDP-AIERAVLDQWIA
Mflv_1535|M.gilvum_PYR-GCK -----VVHHVCALNAILVDPTVGPLLRNVIAASASDP-AIQQALCDQWIA
Mb3192c|M.bovis_AF2122/97 -----IRMMIAATRDVFTTPVVRAALPGLVADMTADA-ELNARVLARFAD
Rv3167c|M.tuberculosis_H37Rv -----IRMMIAATRDVFTTPVVRAALPGLVADMTADA-ELNARVLARFAD
MAV_4057|M.avium_104 -----MRMMIEATRDVFTTPVVRAALPGLVADMTADP-ALNARVMSRFAD
MMAR_0340|M.marinum_M -----LREMVRRTTAVLSTPAAKAALPGLIGEMAADP-TLHSALLVRFGE
MUL_4780|M.ulcerans_Agy99 -----LREMVRRTTAVLSTPAAKAAQPGLIGEMAADP-TLHSALLVRFGE
MAB_4749c|M.abscessus_ATCC_199 -----LRAQMRAFLGVIRDTAAGAIIGELIGQAQVDP-ELKAAFLQRYSG
MSMEG_5301|M.smegmatis_MC2_155 -----LRSQLHAFLRVIRGTPAGTVIAELIGGAQTDP-ELKAAFMQRYSG
TH_4110|M.thermoresistible__bu DPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHP-ALLRTYWEHYIL
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
: . : ::
Mvan_5223|M.vanbaalenii_PYR-1 PRRAAVAVTLREAVDRGELPGDVDIEVAVDALVSPPYYRLVLGM----PP
Mflv_1535|M.gilvum_PYR-GCK PRRAAVAATVRDAVEGGELRDDVDVEVVVDAVVSPPYYRLVLGM----PP
Mb3192c|M.bovis_AF2122/97 LF-AAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYP---DDM
Rv3167c|M.tuberculosis_H37Rv LF-AAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYP---DDM
MAV_4057|M.avium_104 LF-TAVRVRLGEAVDRGEAHPDVDPDRLIELIGGATMLRMLLRP---EEE
MMAR_0340|M.marinum_M IFGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPG
MUL_4780|M.ulcerans_Agy99 IFGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPG
MAB_4749c|M.abscessus_ATCC_199 PRRALAVAAIRRAQERGQLRANVDPEVMVDQLWGACYHRLLVPD----QP
MSMEG_5301|M.smegmatis_MC2_155 PRRSFAVAAMRRAQERGQLAAHVDPETVIDQLWGACYNRLLVPD----QP
TH_4110|M.thermoresistible__bu PRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQPE-----P
MLBr_01070|M.leprae_Br4923 YN-TAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK--PLI
. : : .
Mvan_5223|M.vanbaalenii_PYR-1 LAAEAVDRLVETVWSGCRH--------
Mflv_1535|M.gilvum_PYR-GCK LDDRAIDGLVRAVWRGYRH--------
Mb3192c|M.bovis_AF2122/97 LDDAWVDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv LDDAWVDQTTAIVVRGVHRAAPGGSVV
MAV_4057|M.avium_104 LDDAWVEQTTAIVVHGVRR--------
MMAR_0340|M.marinum_M VGDAWIDRTTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 VGDAWIDRTTTLLLKGIRKGTPQ----
MAB_4749c|M.abscessus_ATCC_199 LTAGFVDALLDNLFKGIGA--------
MSMEG_5301|M.smegmatis_MC2_155 LSEQFVDALLDNLFRGIGA--------
TH_4110|M.thermoresistible__bu PSARQLRCYLEVAYRQVGLLP------
MLBr_01070|M.leprae_Br4923 PDKKVIDTLVHIWLASIYGS-------
: