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LTTNPRRGRGRRPAQDVRRDVLAAVADLLFTEGMAGFTIDKVAARSGVSKVTIYKWWPSKGALALDGYFA KVEPRLAFPDTGDIEADLRSQLHAFLRVIRGTPAGTVIAELIGGAQTDPELKAAFMQRYSGPRRSFAVAA MRRAQERGQLAAHVDPETVIDQLWGACYNRLLVPDQPLSEQFVDALLDNLFRGIGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5301 | - | - | 100% (196) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5567 | - | 2e-25 | 36.00% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5340 | - | 5e-19 | 31.79% (195) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 3e-16 | 31.61% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 7e-24 | 31.35% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 3e-16 | 31.61% (193) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-06 | 34.65% (127) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4749c | - | 3e-82 | 75.38% (195) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1394 | - | 2e-15 | 30.57% (193) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 6e-17 | 30.69% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-22 | 32.47% (194) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 4e-15 | 30.05% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | 2e-24 | 30.27% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5301|M.smegmatis_MC2_155 ------MT-TNPRR-GRGRRPA----QDVRRDVLAAVADLLFTEGMAGFT
MAB_4749c|M.abscessus_ATCC_199 ------MNGTRPRQPRRGRRPT----EEVREEVLQAAGELLFTEGMGGFT
Mb3192c|M.bovis_AF2122/97 ---MKADLPSLDKAPGAGRPRD----PRIDSAILSATAELLVQIGYSNLS
Rv3167c|M.tuberculosis_H37Rv ---MKADLPSLDKAPGAGRPRD----PRIDSAILSATAELLVQIGYSNLS
MMAR_1394|M.marinum_M ---MKADPSSLDKAPGAGRPRD----PRIDFAILSATMELLVQIGYSNLS
MUL_2482|M.ulcerans_Agy99 ---MKADPSSLDKAPGAGRPRD----PRIDFAILSATMELLVQIGYSNLS
MAV_5165|M.avium_104 --------------MDFGRPRD----PRIDAAVLRATVELLAETGYPGLL
Mflv_1535|M.gilvum_PYR-GCK ------------MASRRGRPRS----EAVRSAVLTAAAELALAGGPAAAS
Mvan_5223|M.vanbaalenii_PYR-1 -------MVEAGSAARRGRPRS----EAARSAVLTAAAELALEGGPAAAT
TH_4110|M.thermoresistible__bu --VTATDAAATGRAAARGRPRD----PALDSAILDAALEIFVEQGISALS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
** :* .. :
MSMEG_5301|M.smegmatis_MC2_155 IDKVAARSGVSKVTIYKWWPSKGALALDGYFAK-VEPRLAFPD-----TG
MAB_4749c|M.abscessus_ATCC_199 IDKVAALSGASKMTIYKWWPSKGALALDGYFRK-VEPDLNFPD-----SG
Mb3192c|M.bovis_AF2122/97 LAAVAERAGTTKSALYRRWSSKAELVHEAAFP--AAPTALQAA-----AG
Rv3167c|M.tuberculosis_H37Rv LAAVAERAGTTKSALYRRWSSKAELVHEAAFP--AAPTALQAA-----AG
MMAR_1394|M.marinum_M LAAVAERAGTTKSALYRRWSSKAELVHEAAFP--VTPSALSAP-----AG
MUL_2482|M.ulcerans_Agy99 LAAVAERAGTTKSALYRRWSSKAELVHEAAFP--VTPSALSAP-----AG
MAV_5165|M.avium_104 VSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFP--VGADTAIPD-----TG
Mflv_1535|M.gilvum_PYR-GCK VEAIARRAEVSRTTIYKWWPSAPAIVLEGLLDS-VRDSITRPP-----GS
Mvan_5223|M.vanbaalenii_PYR-1 VEAIAKRAHVSRTTIYKWWPSAASIVLEGLLDA-VRASITRPS-----GS
TH_4110|M.thermoresistible__bu IEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR-VSAELAWPTPAEASVS
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* : : ::* :.. : . .
MSMEG_5301|M.smegmatis_MC2_155 DIEADLRSQLHAFLRVIRGTPAGTVIAELIGGAQTDP-ELKAAFMQRYSG
MAB_4749c|M.abscessus_ATCC_199 EIERDLRAQMRAFLGVIRDTAAGAIIGELIGQAQVDP-ELKAAFLQRYSG
Mb3192c|M.bovis_AF2122/97 DIAADIRMMIAATRDVFTTPVVRAALPGLVADMTADA-ELNARVLARFAD
Rv3167c|M.tuberculosis_H37Rv DIAADIRMMIAATRDVFTTPVVRAALPGLVADMTADA-ELNARVLARFAD
MMAR_1394|M.marinum_M DFAGDIRMMVAATRDVFTTPVVRAALPGLVADMTADA-DLNARVLSRFTE
MUL_2482|M.ulcerans_Agy99 DFAGDIRMMVAATRDVFTTPVVRAALPGLVADMTAEA-DLNARVLSRFTE
MAV_5165|M.avium_104 STADDLREMVRRTMVFLTTPAAKAALPGLIGEMAADP-SLHSALLERFAG
Mflv_1535|M.gilvum_PYR-GCK TSVEAVVHHVCALNAILVDPTVGPLLRNVIAASASDP-AIQQALCDQWIA
Mvan_5223|M.vanbaalenii_PYR-1 TSVQALVHHVSSLNAILADPAVGPLLRNVIAASTSDP-AIERAVLDQWIA
TH_4110|M.thermoresistible__bu DPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHP-ALLRTYWEHYIL
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
: . : ::
MSMEG_5301|M.smegmatis_MC2_155 PRRSFAVAAMRRAQERGQLAAH---VDPETVIDQLWGACYNR--LLVPDQ
MAB_4749c|M.abscessus_ATCC_199 PRRALAVAAIRRAQERGQLRAN---VDPEVMVDQLWGACYHR--LLVPDQ
Mb3192c|M.bovis_AF2122/97 LFAA-VRMRLREAVDRGEAHPD---VDPDRLIELIGGATMLRM-LLYPDD
Rv3167c|M.tuberculosis_H37Rv LFAA-VRMRLREAVDRGEAHPD---VDPDRLIELIGGATMLRM-LLYPDD
MMAR_1394|M.marinum_M LFAT-VRIRLQEAVDRGEAHPD---VDPNRMIELIGGATMLRV-LLYPDQ
MUL_2482|M.ulcerans_Agy99 LFAT-VRIRLQEAVDRGEAHPD---VDPNRMIELIGGATMLRV-LLYPDQ
MAV_5165|M.avium_104 AIGGGLADWLAAAAARGEARPD---VTAAELAETIAGVTLVAL-LTRP-T
Mflv_1535|M.gilvum_PYR-GCK PRRAAVAATVRDAVEGGELRDD---VDVEVVVDAVVSPPYYR--LVLGMP
Mvan_5223|M.vanbaalenii_PYR-1 PRRAAVAVTLREAVDRGELPGD---VDIEVAVDALVSPPYYR--LVLGMP
TH_4110|M.thermoresistible__bu PRRTAAIALLRRARDLGTVAAD---ADLDVLVDMLAGAVTYR--VLQPEP
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPDK
. . . . : : .
MSMEG_5301|M.smegmatis_MC2_155 PLSEQFVDALLDNLFRGIGA--------
MAB_4749c|M.abscessus_ATCC_199 PLTAGFVDALLDNLFKGIGA--------
Mb3192c|M.bovis_AF2122/97 MLDDAWVDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv MLDDAWVDQTTAIVVRGVHRAAPGGSVV
MMAR_1394|M.marinum_M MLDEAWVDQTTAILVHGVTR--------
MUL_2482|M.ulcerans_Agy99 MLDEAWVDQTTAILVHGVTR--------
MAV_5165|M.avium_104 ELDDAWVDRTTRLLLKGISA--------
Mflv_1535|M.gilvum_PYR-GCK PLDDRAIDGLVRAVWRGYRH--------
Mvan_5223|M.vanbaalenii_PYR-1 PLAAEAVDRLVETVWSGCRH--------
TH_4110|M.thermoresistible__bu P-SARQLRCYLEVAYRQVGLLP------
MLBr_01070|M.leprae_Br4923 KVIDTLVHIWLASIYGS-----------
: