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MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLA AFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1556 | - | - | 100% (202) | Possible regulatory protein |
| M. tuberculosis H37Rv | Rv1167c | - | 3e-15 | 28.19% (188) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-11 | 31.58% (171) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 1e-112 | 100.00% (202) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_3021 | - | 8e-61 | 58.64% (191) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0989 | - | 1e-65 | 63.35% (191) | putative HTH-type transcriptional regulator TetR |
| M. marinum M | MMAR_1695 | - | 2e-86 | 79.29% (198) | regulatory protein |
| M. avium 104 | MAV_3866 | - | 1e-84 | 77.32% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 3e-19 | 36.53% (167) | putative TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0688 | - | 8e-14 | 32.46% (191) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1934 | - | 3e-88 | 79.60% (201) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 6e-18 | 32.39% (176) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1556|M.tuberculosis_H37Rv MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVA
Mb1581|M.bovis_AF2122/97 MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVA
MMAR_1695|M.marinum_M ----MTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVA
MUL_1934|M.ulcerans_Agy99 -MGAMTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVA
MAV_3866|M.avium_104 ----MTQ---TADRCEQASPWSPREAEILAVTLRLLQEHGYDQLTVDAVA
MAB_0989|M.abscessus_ATCC_1997 MASDVSTGLTKAARGRQVSQWTPREVELLKVTLRLLQEHGYDRLSVDEVA
Mflv_3021|M.gilvum_PYR-GCK -MCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYDRLTVEAVA
MSMEG_3834|M.smegmatis_MC2_155 -------------MTAGRPQEARVTTVILDAVLSELAEHGFGSMTVDGVA
TH_0688|M.thermoresistible__bu --MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNLTMSAVA
Mvan_2727|M.vanbaalenii_PYR-1 ---------------MGRRRGAELDAAIRAAVLELLAEHGPDGVTMDAVA
. : . * : * . :::. **
Rv1556|M.tuberculosis_H37Rv ASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGE
Mb1581|M.bovis_AF2122/97 ASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGE
MMAR_1695|M.marinum_M NTARASKATVYRRWPSKAELVLAAFIEGVRQVAVAPNTGSLRDDLVKIGE
MUL_1934|M.ulcerans_Agy99 NTARASKATVYRRWPSKAELVLAAFIEGVRQVAVAPNTGSLRDDLVKIGE
MAV_3866|M.avium_104 GAAHASKATVYRRWPSKAELVLAAFIEGVRQVAVPPNTGTLRGDLLALGE
MAB_0989|M.abscessus_ATCC_1997 AESKASKATIYRRWPSKAELVLAAFIEGMRAQLVRPNTGSLREDLLRIGT
Mflv_3021|M.gilvum_PYR-GCK TQAKASKATLYRRWPSKSDLVLAAFVEGTRLAAVPPRTGSLRDDLLRVGA
MSMEG_3834|M.smegmatis_MC2_155 KRAGAGKGAIYRRWPSKIEMTAAAMRTLALPEGAAPDTGSLYGDVLALLA
TH_0688|M.thermoresistible__bu ERAGTTKTALYRRWSSKPELVYAATAP-TDPVDTVESSDDVAGIVRALIE
Mvan_2727|M.vanbaalenii_PYR-1 VTAQTSKPVLYRRWPDRRALLRDTLLGIATSAFPTVDTGGFRGDMLAVLR
: : * .:****..: : : :. . : :
Rv1556|M.tuberculosis_H37Rv LICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQ
Mb1581|M.bovis_AF2122/97 LICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQ
MMAR_1695|M.marinum_M GICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQQVLQQ
MUL_1934|M.ulcerans_Agy99 GICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQQVLQQ
MAV_3866|M.avium_104 TVCEQVGHHAS--TIRAVMFEVSRHPALNDALQHQFLDQRRALIEHVLHQ
MAB_0989|M.abscessus_ATCC_1997 NALADVRRNTP--VMRGLLIEIERNPALTKAFRTKFVDERKALIDDVLFA
Mflv_3021|M.gilvum_PYR-GCK SVCQQACEHAS--TMRAVLNEMSHNPDLRKAMQDEFVHQHKLVIDEVLAE
MSMEG_3834|M.smegmatis_MC2_155 DVNRWIGDERMRRLYPDLLAEAQRNPVLAEALMDTVGTPRRARARDILDR
TH_0688|M.thermoresistible__bu RNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVG-SLVEALRRRLAE
Mvan_2727|M.vanbaalenii_PYR-1 AWAALFTGDSA-ALMRSAIGAVTADPELAATFRTDVIGARKQEMDAIITR
: .* * : . :
Rv1556|M.tuberculosis_H37Rv AVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP
Mb1581|M.bovis_AF2122/97 AVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP
MMAR_1695|M.marinum_M AVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVDDFIMP
MUL_1934|M.ulcerans_Agy99 AVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVDDFIMP
MAV_3866|M.avium_104 AVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSRRTVQALVDGFLIP
MAB_0989|M.abscessus_ATCC_1997 AVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTADTVRTLVDDVIMP
Mflv_3021|M.gilvum_PYR-GCK AVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLKSVRTLVDKVLLP
MSMEG_3834|M.smegmatis_MC2_155 AATRGELAPGADSELLVDAMGALVFWRLIALFRPVTSEYLDRVARAICAF
TH_0688|M.thermoresistible__bu AAGRGEVQSGVDADRLTELIGGSVMFRMVLHPDEPITERWADEVAAILIR
Mvan_2727|M.vanbaalenii_PYR-1 GVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDDEVVTRLVDEVLIP
.. ***: . : : : . : * : . .
Rv1556|M.tuberculosis_H37Rv -----SLTRSTG--
Mb1581|M.bovis_AF2122/97 -----SLTRSTG--
MMAR_1695|M.marinum_M -----GLTQATG--
MUL_1934|M.ulcerans_Agy99 -----GLTQATG--
MAV_3866|M.avium_104 -----GLTAR----
MAB_0989|M.abscessus_ATCC_1997 -----SLTRER---
Mflv_3021|M.gilvum_PYR-GCK SLGHRGLSKPDGQ-
MSMEG_3834|M.smegmatis_MC2_155 -----ARTGPV---
TH_0688|M.thermoresistible__bu -----GVTKEG---
Mvan_2727|M.vanbaalenii_PYR-1 ------VTRPYYEV
: