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MMTRRRGAELDAAIRSAVLDLLAGHGPEAVTMDAVAVAAGTSKPVLYRRWPDRRALLRDTLMAVASTSFP RPDTGTFRGDLLAVLRAWAQLFTGDTGPLMRSVIVAVASDPDLESTFRSDVLGMRKAEMTTLIGRAVERG EVRPDVPVELVRELGQSVLWHRLLITGDPITDELVTQLVDEVLIPVTRPYYDQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3683 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 3e-19 | 32.79% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3021 | - | 2e-17 | 29.67% (182) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 6e-18 | 28.57% (182) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1167c | - | 6e-18 | 28.57% (182) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3462c | - | 1e-19 | 35.23% (176) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4284 | - | 3e-16 | 29.35% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_3866 | - | 9e-19 | 34.66% (176) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3319 | - | 4e-20 | 33.33% (189) | repressor protein |
| M. thermoresistible (build 8) | TH_3283 | - | 4e-15 | 29.19% (185) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 3e-16 | 29.89% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 1e-80 | 75.92% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3683|M.gilvum_PYR-GCK -----------------MMTRRRGAELDAAIRSAVLDLLAGHGPEAVTMD
Mvan_2727|M.vanbaalenii_PYR-1 ------------------MGRRRGAELDAAIRAAVLELLAEHGPDGVTMD
TH_3283|M.thermoresistible__bu --------MPGSGARSP--GRPRDPALDDAIRAAARDVVVEHGYDATTLA
MUL_2482|M.ulcerans_Agy99 -----MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLA
Mb1199c|M.bovis_AF2122/97 ------MTVSAPAKANPYR--RRGEVLERALYDATLAELESAGYGGLTME
Rv1167c|M.tuberculosis_H37Rv ------MTVSAPAKANPYR--RRGEVLERALYDATLAELESAGYGGLTME
MMAR_4284|M.marinum_M ------MAQLSEPMLTPYRSRRRGEVLERALYSATLAELIAVGYGRLTME
MAB_3462c|M.abscessus_ATCC_199 MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDLLVARGYAGVTME
MAV_3866|M.avium_104 ----------MTQTADRCEQASPWSPREAEILAVTLRLLQEHGYDQLTVD
MSMEG_3319|M.smegmatis_MC2_155 ------------------MQRRRGSALESAILDAGWDQLIEAGYDGFTIE
: . : * ::
Mflv_3683|M.gilvum_PYR-GCK AVAVAAGTSKPVLYRRWPDRRALLRDTLMAVASTS-FPRPDTGTFRGDLL
Mvan_2727|M.vanbaalenii_PYR-1 AVAVTAQTSKPVLYRRWPDRRALLRDTLLGIATSA-FPTVDTGGFRGDML
TH_3283|M.thermoresistible__bu LIADRAGVSVPTIYRRWQHKHELIEEAVLHLDTFE-LPEP-TGDLEADLG
MUL_2482|M.ulcerans_Agy99 AVAERAGTTKSALYRRWSSKAELVHEAAFPVTPSA-LSAP-AGDFAGDIR
Mb1199c|M.bovis_AF2122/97 GIAARAQTGKAALYRRWAGKRELVLAAVQYALPPV-PEPRADRSARENLL
Rv1167c|M.tuberculosis_H37Rv GIAARAQTGKAALYRRWAGKRELVLAAVQYALPPV-PEPRADRSARENLL
MMAR_4284|M.marinum_M GIAARAQTGKAALYRRWASKHDLVQAALQYAVPPP-PEPRPGRSARENLL
MAB_3462c|M.abscessus_ATCC_199 GIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQ-LDPPDLGGLEADLR
MAV_3866|M.avium_104 AVAGAAHASKATVYRRWPSKAELVLAAFIEGVRQV-AVPPNTGTLRGDLL
MSMEG_3319|M.smegmatis_MC2_155 AVATRSGSARSVLYRRWPSRLDLLKAVIRHRGEIDRIPVPDTGTLRDDVV
:* : .:** * : :: . ::
Mflv_3683|M.gilvum_PYR-GCK AVLRAWAQLFTG-DTGPLMRSVIVAVASDPD-LESTFRSDVLGMRKAEMT
Mvan_2727|M.vanbaalenii_PYR-1 AVLRAWAALFTG-DSAALMRSAIGAVTADPE-LAATFRTDVIGARKQEMD
TH_3283|M.thermoresistible__bu TWVRLFLTVAMEPAARAAVPGLMSAYSRNPD-DYRRLMTRGELPVRAAIA
MUL_2482|M.ulcerans_Agy99 MMVAATRDVFTTPVVRAALPGLVADMTAEAD-LNARVLSR-FTELFATVR
Mb1199c|M.bovis_AF2122/97 AVFTANCEILAG-KTALPSMEIVSQLLHEPE-LRAIFINSVWAPRLRIVE
Rv1167c|M.tuberculosis_H37Rv AVFTANCEILAG-KTALPSMEIVSQLLHEPE-LRAIFINSVWAPRLRIVE
MMAR_4284|M.marinum_M TVFTAHRDVLAG-KTEFPGLVAIGQLIHEPE-LRAIFANSVVHPRLKIID
MAB_3462c|M.abscessus_ATCC_199 HHLSATAQFLAADDAGAVFRALIGQSQHDGQ-LADDFRGRYLREQQARDQ
MAV_3866|M.avium_104 ALGETVCEQVGH--HASTIRAVMFEVSRHPA-LNDALQHQFLDQRRALIE
MSMEG_3319|M.smegmatis_MC2_155 AVLTEFNDRRSR--IIGIIAARLGAYFDEPDGSPKQLRDLFLSDGPTAME
: . .
Mflv_3683|M.gilvum_PYR-GCK TLIGRAVERGEVRPDVPVELVRELGQSVLWHRLLITGDPITDELVTQLVD
Mvan_2727|M.vanbaalenii_PYR-1 AIITRGVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDDEVVTRLVD
TH_3283|M.thermoresistible__bu AMLERAKAAGQAAPDCDPDAVFELIRGATFLRALTHSDEDAEAFCTRITE
MUL_2482|M.ulcerans_Agy99 IRLQEAVDRGEAHPDVDPNRMIELIGGATMLRVLLYPDQMLDEAWVDQTT
Mb1199c|M.bovis_AF2122/97 SILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIID
Rv1167c|M.tuberculosis_H37Rv SILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIID
MMAR_4284|M.marinum_M SVLRAAIREGDLDPDTVTPFTARIGPALMNQHFILTGTPPNRRELALIVD
MAB_3462c|M.abscessus_ATCC_199 IPIARAVARGELPADVDVAHVAEQLVAPLYYRVIVTGETVDAAFVDRIVE
MAV_3866|M.avium_104 HVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSRRTVQALVD
MSMEG_3319|M.smegmatis_MC2_155 TIVERAVQRGELAAVP-PARIVSLPADLVRHELLMTMTAVPADTIREIVD
: . *: . . :
Mflv_3683|M.gilvum_PYR-GCK EVLIPVTRPYYDQ---
Mvan_2727|M.vanbaalenii_PYR-1 EVLIPVTRPYYEV---
TH_3283|M.thermoresistible__bu AVLRAVRS--------
MUL_2482|M.ulcerans_Agy99 AILVHGVTR-------
Mb1199c|M.bovis_AF2122/97 AMILT----TGERRES
Rv1167c|M.tuberculosis_H37Rv AMILT----TGERRES
MMAR_4284|M.marinum_M TVIPPKRTSTCDNCDN
MAB_3462c|M.abscessus_ATCC_199 DFLRRRE---------
MAV_3866|M.avium_104 GFLIPGLTAR------
MSMEG_3319|M.smegmatis_MC2_155 DIFLPLATRSGQER--
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