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MPTDPNGPAAPRRRSEKSRTAIVTATRELLLERGFDGLTIEAVAARAGVGKQTIYRWWPTRPALVADVML EDADRLLASVEHSGDLAADLVGWVGKLVTSLTTPRGSAMLRTLTVACMEHEDTAVKLRAGFSAPLHDSVR ARLLAEGVDAATAESAADAIVGGVVYPILSGAQRYSRRRAEHTTRLIVAALTAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5267 | - | - | 100% (194) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4057 | - | 1e-13 | 30.15% (199) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5165 | - | 3e-13 | 29.26% (188) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 2e-13 | 32.91% (158) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2374 | - | 4e-62 | 63.24% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-13 | 32.91% (158) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 2e-06 | 36.62% (71) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 8e-14 | 40.00% (100) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1394 | - | 4e-12 | 29.56% (203) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6564 | - | 5e-62 | 65.38% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3283 | - | 2e-11 | 31.95% (169) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 2e-12 | 29.56% (203) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4272 | - | 1e-64 | 66.30% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 -----MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLA
Rv3167c|M.tuberculosis_H37Rv -----MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLA
MMAR_1394|M.marinum_M -----MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLA
MUL_2482|M.ulcerans_Agy99 -----MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLA
TH_3283|M.thermoresistible__bu --------MPGSGARSP--GRPRDPALDDAIRAAARDVVVEHGYDATTLA
Mflv_2374|M.gilvum_PYR-GCK ---------MTAE---ISTPRRRSEKSRVAIVDATRGLLLERGFDKLTIE
Mvan_4272|M.vanbaalenii_PYR-1 ---------MATD---IAAPRRRSEKSRTAIVEATRKLLMERGFDKLTIE
MAV_5267|M.avium_104 ---------MPTDPNGPAAPRRRSEKSRTAIVTATRELLLERGFDGLTIE
MSMEG_6564|M.smegmatis_MC2_155 ---------MTTA----EAPRRRSEKSRVAIVEATRALLLERGFDGLSIE
MAB_3462c|M.abscessus_ATCC_199 MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDLLVARGYAGVTME
MLBr_00717|M.leprae_Br4923 ---------MTTAR-----RRLSPEDRRAELLALGAEVFGKRPYDEVRID
: : : :. : :
Mb3192c|M.bovis_AF2122/97 AVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQ----AAAGDIAAD
Rv3167c|M.tuberculosis_H37Rv AVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQ----AAAGDIAAD
MMAR_1394|M.marinum_M AVAERAGTTKSALYRRWSSKAELVHEAAFPVTPSALS----APAGDFAGD
MUL_2482|M.ulcerans_Agy99 AVAERAGTTKSALYRRWSSKAELVHEAAFPVTPSALS----APAGDFAGD
TH_3283|M.thermoresistible__bu LIADRAGVSVPTIYRRWQHKHELIEEAVLHLDTFELP----EPTGDLEAD
Mflv_2374|M.gilvum_PYR-GCK AVAARAGVGKQTIYRWWPSRHALVADVILEDADRILRPI--DHTDDVAAD
Mvan_4272|M.vanbaalenii_PYR-1 AVAARAGVGKQTIYRWWPSRHALVADVTLEDADRILRPV--ARTDDVAAD
MAV_5267|M.avium_104 AVAARAGVGKQTIYRWWPTRPALVADVMLEDADRLLASV--EHSGDLAAD
MSMEG_6564|M.smegmatis_MC2_155 AVAAKAGVGKQTIYRWWPSRHALVADVLLEDADKILARM--PKTDDVTAD
MAB_3462c|M.abscessus_ATCC_199 GIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQLDP---PDLGGLEAD
MLBr_00717|M.leprae_Br4923 EIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMF
:* **. :*: : : .. . ..
Mb3192c|M.bovis_AF2122/97 IRMMIAATRDVFTTPVV-RAALPGLVADMTAD------AELNARVLAR-F
Rv3167c|M.tuberculosis_H37Rv IRMMIAATRDVFTTPVV-RAALPGLVADMTAD------AELNARVLAR-F
MMAR_1394|M.marinum_M IRMMVAATRDVFTTPVV-RAALPGLVADMTAD------ADLNARVLSR-F
MUL_2482|M.ulcerans_Agy99 IRMMVAATRDVFTTPVV-RAALPGLVADMTAE------ADLNARVLSR-F
TH_3283|M.thermoresistible__bu LGTWVRLFLTVAMEPAA-RAAVPGLMSAYSRN------PDDYRRLMTRGE
Mflv_2374|M.gilvum_PYR-GCK VCAWATGLAKALTTARG-NAMLRILTAAGMEH------PDTAARLQAGFS
Mvan_4272|M.vanbaalenii_PYR-1 LCAWAVTLATALTTVRG-NAMLRALTTAGVEH------QDTAARLHAGFN
MAV_5267|M.avium_104 LVGWVGKLVTSLTTPRG-SAMLRTLTVACMEH------EDTAVKLRAGFS
MSMEG_6564|M.smegmatis_MC2_155 LASWAGTLAAALTTRRG-HAMLKTLMAASLEH------EDTAARLREGFS
MAB_3462c|M.abscessus_ATCC_199 LRHHLSATAQFLAADDA-GAVFRALIGQSQHD------GQLADDFRGRYL
MLBr_00717|M.leprae_Br4923 EEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHI
* . :
Mb3192c|M.bovis_AF2122/97 ADLFAAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD
Rv3167c|M.tuberculosis_H37Rv ADLFAAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD
MMAR_1394|M.marinum_M TELFATVRIRLQEAVDRGEAHPDVDPNRMIELIGGATMLRVLLYPDQMLD
MUL_2482|M.ulcerans_Agy99 TELFATVRIRLQEAVDRGEAHPDVDPNRMIELIGGATMLRVLLYPDQMLD
TH_3283|M.thermoresistible__bu LPVRAAIAAMLERAKAAGQAAPDCDPDAVFELIRGATFLRALTHSDED-A
Mflv_2374|M.gilvum_PYR-GCK VPLHDTVRNRLAASGFTDRAVQDG-ADAIVG-----GIVYAILNEGRAFE
Mvan_4272|M.vanbaalenii_PYR-1 QPIHDAVRGRLTAEGLTAESARDA-TDAIVG-----GIVYAILSEGRSFD
MAV_5267|M.avium_104 APLHDSVRARLLAEGVDAATAESA-ADAIVG-----GVVYPILSGAQRYS
MSMEG_6564|M.smegmatis_MC2_155 RPLIESVRDRLRDEDIDADHAQAA-ADALLG-----AVVNAVLSEGRSYS
MAB_3462c|M.abscessus_ATCC_199 REQQARDQIPIARAVARGELPADVDVAHVAEQLVA-PLYYRVIVTGETVD
MLBr_00717|M.leprae_Br4923 MSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDA
: .
Mb3192c|M.bovis_AF2122/97 DAWVDQTTAIVVRGVHRAAPGGSVV------------
Rv3167c|M.tuberculosis_H37Rv DAWVDQTTAIVVRGVHRAAPGGSVV------------
MMAR_1394|M.marinum_M EAWVDQTTAILVHGVTR--------------------
MUL_2482|M.ulcerans_Agy99 EAWVDQTTAILVHGVTR--------------------
TH_3283|M.thermoresistible__bu EAFCTRITEAVLRAVRS--------------------
Mflv_2374|M.gilvum_PYR-GCK SRRAESISRAVLAGISAR-------------------
Mvan_4272|M.vanbaalenii_PYR-1 PHRAESITRTVIAGITTR-------------------
MAV_5267|M.avium_104 RRRAEHTTRLIVAALTAG-------------------
MSMEG_6564|M.smegmatis_MC2_155 RQRAETSARIIVAGLRP--------------------
MAB_3462c|M.abscessus_ATCC_199 AAFVDRIVEDFLRRRE---------------------
MLBr_00717|M.leprae_Br4923 DRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ
.: