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M. smegmatis MC2 155 MSMEG_3834 (-)

annotation: putative TetR-family protein transcriptional regulator
coordinates: 3905025 - 3905606
length: 193

TAGRPQEARVTTVILDAVLSELAEHGFGSMTVDGVAKRAGAGKGAIYRRWPSKIEMTAAAMRTLALPEGA
APDTGSLYGDVLALLADVNRWIGDERMRRLYPDLLAEAQRNPVLAEALMDTVGTPRRARARDILDRAATR
GELAPGADSELLVDAMGALVFWRLIALFRPVTSEYLDRVARAICAFARTGPV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3834--100% (193)putative TetR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_5340-6e-3340.80% (174) TetR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_3410-4e-2336.02% (186) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1581-2e-1936.53% (167) regulatory protein
M. gilvum PYR-GCKMflv_4384-8e-1829.83% (181) TetR family transcriptional regulator
M. tuberculosis H37RvRv1556-2e-1936.53% (167) regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3151-3e-2037.04% (189) TetR family transcriptional regulator
M. marinum MMMAR_1695-5e-1832.37% (173) regulatory protein
M. avium 104MAV_4754-2e-2039.25% (186) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0688-2e-1933.33% (180) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_4780-4e-1830.21% (192) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1961-4e-1729.35% (184) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1581|M.bovis_AF2122/97            ---------MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRL
Rv1556|M.tuberculosis_H37Rv         ---------MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRL
MMAR_1695|M.marinum_M               -------------MTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRL
MAB_3151|M.abscessus_ATCC_1997      ---------MTKNAATQRQRTSGRLNRS-LDIAILEAAFVTLAEQGYDAM
MAV_4754|M.avium_104                ---MGQPQSQMEPESKLRQRTEGRLDRS-RDPAILDAALAALAEHGYDAT
Mflv_4384|M.gilvum_PYR-GCK          MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVELLAESSYAEL
Mvan_1961|M.vanbaalenii_PYR-1       ---------------------MGRPRNRAIDDAVLRATVELISESSYAEL
MUL_4780|M.ulcerans_Agy99           -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
TH_0688|M.thermoresistible__bu      --------MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNL
MSMEG_3834|M.smegmatis_MC2_155      -------------------MTAGRPQEARVTTVILDAVLSELAEHGFGSM
                                                                     :* ..   : * .:   

Mb1581|M.bovis_AF2122/97            TVDAVAASARASKATVYRRWPSKAELVLAAFIEG---IRQVAVPPNTGNL
Rv1556|M.tuberculosis_H37Rv         TVDAVAASARASKATVYRRWPSKAELVLAAFIEG---IRQVAVPPNTGNL
MMAR_1695|M.marinum_M               TIDAVANTARASKATVYRRWPSKAELVLAAFIEG---VRQVAVAPNTGSL
MAB_3151|M.abscessus_ATCC_1997      SMDNIAARAGVGKAAIYRRWSSKAALTADAILHGRPSLGKLDEVPDTGSL
MAV_4754|M.avium_104                NMNDIAARAGVGKAAIYRRWSSKAALMTDALIYWRPELLN-DDAPDTGSL
Mflv_4384|M.gilvum_PYR-GCK          SLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFPLG----ADTAIPGSGSL
Mvan_1961|M.vanbaalenii_PYR-1       SLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFPVD----ATIEIPRTGSL
MUL_4780|M.ulcerans_Agy99           LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPID----AATAVPDTGSP
TH_0688|M.thermoresistible__bu      TMSAVAERAGTTKTALYRRWSSKPELVYAATAPTD----PVDTVESSDDV
MSMEG_3834|M.smegmatis_MC2_155      TVDGVAKRAGAGKGAIYRRWPSKIEMTAAAMRTLA---LPEGAAPDTGSL
                                     :. :*  * . * ::**** .*  :   *                :.. 

Mb1581|M.bovis_AF2122/97            RDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRK
Rv1556|M.tuberculosis_H37Rv         RDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRK
MMAR_1695|M.marinum_M               RDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRK
MAB_3151|M.abscessus_ATCC_1997      RGDLHSLYEARDFGDDQVLTGNLLAGIIAEAVNDPTLAAALDDLLVSQTH
MAV_4754|M.avium_104                AGDLDAIVKRAKRNDNALISNDLVLRVALEAAHDPELATALNDLILFKGR
Mflv_4384|M.gilvum_PYR-GCK          EADVREMTRRTLAVLSTPAALAALPGLVGEMASDPTLHTALLERFGDILV
Mvan_1961|M.vanbaalenii_PYR-1       HGDVREMLRRTLAVLSTPAARAALPGLVGEMASDPTLHAALLERFADVLV
MUL_4780|M.ulcerans_Agy99           VDDLREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFG
TH_0688|M.thermoresistible__bu      AGIVRALIERNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVG-SLV
MSMEG_3834|M.smegmatis_MC2_155      YGDVLALLADVNRWIGDERMRRLYPDLLAEAQRNPVLAEALMDTVGTPRR
                                       :  :                   :  :   .* *   *   .     

Mb1581|M.bovis_AF2122/97            ALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQ
Rv1556|M.tuberculosis_H37Rv         ALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQ
MMAR_1695|M.marinum_M               ALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQ
MAB_3151|M.abscessus_ATCC_1997      KRMELVFARAVERGEITQGRDLSLVYDIPLGLSLTAALKRTV-IDETYMH
MAV_4754|M.avium_104                RVLSAVLAQAADRGEIDPNRDWSLVADVLTAMGLLRAISGQR-VDGKFVR
Mflv_4384|M.gilvum_PYR-GCK          RGLTEFLESAVRRGDVRPDVTASDLAEAVAGMTLLALLTR-G---TAVDE
Mvan_1961|M.vanbaalenii_PYR-1       RDLNNYLDSAVRRGEVRRGVTAVELAEAVTGMTLLALITR-G---ANVDD
MUL_4780|M.ulcerans_Agy99           HGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGD
TH_0688|M.thermoresistible__bu      EALRRRLAEAAGRGEVQSGVDADRLTELIGGSVMFRMVLHPD---EPITE
MSMEG_3834|M.smegmatis_MC2_155      ARARDILDRAATRGELAPGADSELLVDAMGALVFWRLIALFRPVTSEYLD
                                          :  *. **::        : :   .  :   :            

Mb1581|M.bovis_AF2122/97            ALVDDVILPSLTRSTG----
Rv1556|M.tuberculosis_H37Rv         ALVDDVILPSLTRSTG----
MMAR_1695|M.marinum_M               LLVDDFIMPGLTQATG----
MAB_3151|M.abscessus_ATCC_1997      RMVEEVILPLVQAPTTHT--
MAV_4754|M.avium_104                RVIDTLILPAVRAAPE----
Mflv_4384|M.gilvum_PYR-GCK          VWLDRTARLITKGISA----
Mvan_1961|M.vanbaalenii_PYR-1       AWIERTAHLITKGISS----
MUL_4780|M.ulcerans_Agy99           AWIDRTTTLLLKGIRKGTPQ
TH_0688|M.thermoresistible__bu      RWADEVAAILIRGVTKEG--
MSMEG_3834|M.smegmatis_MC2_155      RVARAICAFARTGPV-----