For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MHELTPGELAQRSGVAVSALHFYEREGLITSRRTSGNQRRYARETLRRVAFIRMSQRLGIPLSRIREALS TLPNDRVPTSKDWARLSAGWRQDLDDRIMHLQRLRDNLTGCIGCGCLSLKTCQLTNPGDVLAERGPGAAR L
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5450 | soxR | - | 100% (141) | redox-sensitive transcriptional activator SoxR |
| M. smegmatis MC2 155 | MSMEG_3180 | - | 8e-11 | 32.77% (119) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_1969 | - | 9e-08 | 46.30% (54) | MerR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1859 | - | 4e-06 | 38.46% (65) | hypothetical protein Mb1859 |
| M. gilvum PYR-GCK | Mflv_1922 | - | 5e-70 | 87.86% (140) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1828 | - | 4e-06 | 38.46% (65) | hypothetical protein Rv1828 |
| M. leprae Br4923 | MLBr_02075 | - | 7e-06 | 34.85% (66) | hypothetical protein MLBr_02075 |
| M. abscessus ATCC 19977 | MAB_2309c | - | 2e-35 | 49.29% (140) | putative transcriptional regulator |
| M. marinum M | MMAR_2990 | hspR_2 | 7e-07 | 39.34% (61) | heat shock protein transcriptional repressor HspR_2 |
| M. avium 104 | MAV_3222 | - | 2e-10 | 32.77% (119) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_0931 | soxR | 4e-67 | 85.00% (140) | redox-sensitive transcriptional activator SoxR |
| M. ulcerans Agy99 | MUL_0011 | - | 8e-07 | 38.81% (67) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4811 | - | 3e-69 | 87.14% (140) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1922|M.gilvum_PYR-GCK MCTVTATRVEVMEWPHELTP-GDMAA--RSGVAVSALHFYEREG-LITSR
Mvan_4811|M.vanbaalenii_PYR-1 -----------MESAHELTP-GEMAV--RSGVAVSALHFYEREG-LISSR
MSMEG_5450|M.smegmatis_MC2_155 --------------MHELTP-GELAQ--RSGVAVSALHFYEREG-LITSR
TH_0931|M.thermoresistible__bu ------------MGAHELTP-SEMSA--RSGVAVSALHFYEREG-LITSR
MAB_2309c|M.abscessus_ATCC_199 -----------MKGKTELLPIGEVAR--RSGIAVSAVRYYADIG-LVPAE
Mb1859|M.bovis_AF2122/97 ----MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEG-LVTPR
Rv1828|M.tuberculosis_H37Rv ----MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEG-LVTPR
MLBr_02075|M.leprae_Br4923 ----MSAPDSPALVGMSIGAVLDLLRSDFPDVTISKIRFLEAEG-LVTPQ
MAV_3222|M.avium_104 -----------------MLTIGEVAR--RSGVAATTLRYYEQIG-LLPAP
MUL_0011|M.ulcerans_Agy99 ---------------MDGLTVGQVAE--RFGITVRTLHHYDEIGLLIPSR
MMAR_2990|M.marinum_M ---MADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLRLYERHG-LVTPA
.:: :: * *:..
Mflv_1922|M.gilvum_PYR-GCK RTGGNQRRYARETLRRVAFIRMSQR-LGIPLARIREALATL---------
Mvan_4811|M.vanbaalenii_PYR-1 RTSGNQRRYARDTLRRVAFIRMSQR-LGIPLARIREALATL---------
MSMEG_5450|M.smegmatis_MC2_155 RTSGNQRRYARETLRRVAFIRMSQR-LGIPLSRIREALSTL---------
TH_0931|M.thermoresistible__bu RTAGNQRRYPREMLRRVAFIRMSQR-LGIPLARIREALATL---------
MAB_2309c|M.abscessus_ATCC_199 RTSGNVRVFRRHALRRISLIRVATG-FGIPLSEVAEVLSTL---------
Mb1859|M.bovis_AF2122/97 RASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQ---------
Rv1828|M.tuberculosis_H37Rv RASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQ---------
MLBr_02075|M.leprae_Br4923 RSASGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQ---------
MAV_3222|M.avium_104 TRLGGQRRYDEAVLSRLEVIALCKT-AGFALDEIQRLFADD---------
MUL_0011|M.ulcerans_Agy99 RAASGYRVYTSADLTRLSQVIVYRR-LELPLDEIARLLDEGNAVSHLVRQ
MMAR_2990|M.marinum_M RSEGGTRRYSADDLVRLQRVSVLIE-AGINLAGISRILNLE---------
.. * : *: : : * : :
Mflv_1922|M.gilvum_PYR-GCK PSDRVP-------------------------TSKDWARLSAG----WRDD
Mvan_4811|M.vanbaalenii_PYR-1 PTDRVP-------------------------TSKDWARLSAG----WRED
MSMEG_5450|M.smegmatis_MC2_155 PNDRVP-------------------------TSKDWARLSAG----WRQD
TH_0931|M.thermoresistible__bu PSDRVP-------------------------TSKDWAELSAG----WRAD
MAB_2309c|M.abscessus_ATCC_199 PDYRAP-------------------------STRDWQRISRR----WHAH
Mb1859|M.bovis_AF2122/97 PDGELPPFGSPYVLPRLVPVAGDSAG----GVGSDTASVSLTGIRLSRED
Rv1828|M.tuberculosis_H37Rv PDGELPPFGSPYVLPRLVPVAGDSAG----GVGSDTASVSLTGIRLSRED
MLBr_02075|M.leprae_Br4923 PDGELPSFGSPYVAPRLFSVTGGPGAGVGSGVGSDIPAVSPAGVRLSRED
MAV_3222|M.avium_104 APGRPA--------------------------SRALARAKLA-------Q
MUL_0011|M.ulcerans_Agy99 RERVMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVE
MMAR_2990|M.marinum_M ---------------------------------DDNAALAAAN-------
Mflv_1922|M.gilvum_PYR-GCK LDQRILHLERLRDNLA--GCIGCG---CLSLKICALANPGDVLADEGPGA
Mvan_4811|M.vanbaalenii_PYR-1 LDQRIVHLQRLRDNLA--GCIGCG---CLSLKVCALANPGDVLSEEGPGP
MSMEG_5450|M.smegmatis_MC2_155 LDDRIMHLQRLRDNLT--GCIGCG---CLSLKTCQLTNPGDVLAERGPGA
TH_0931|M.thermoresistible__bu LDERILHLQRLRDNLA--DCIGCG---CLSLKTCALSNPDDALAARGPGA
MAB_2309c|M.abscessus_ATCC_199 LEARKNAIADMQEKLT--GCIGCG---CLSMTKCALFNPADILADDGSTG
Mb1859|M.bovis_AF2122/97 LLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEP
Rv1828|M.tuberculosis_H37Rv LLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEP
MLBr_02075|M.leprae_Br4923 LLDRSGVADDLLTALLKAGVITTGPGGFFDEHAIVILQCARALSEYGVEP
MAV_3222|M.avium_104 IDAQLDSLTRARAVIEWGMRCTCP---SIDACTCGIHPTRPAPVGPDVRS
MUL_0011|M.ulcerans_Agy99 TEQKWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPA
MMAR_2990|M.marinum_M -CDLLASNRSLRDAAR--------------AAVRLMNHGRSAENGEGGDT
: .
Mflv_1922|M.gilvum_PYR-GCK ARL-----------------------------------------------
Mvan_4811|M.vanbaalenii_PYR-1 VRL-----------------------------------------------
MSMEG_5450|M.smegmatis_MC2_155 ARL-----------------------------------------------
TH_0931|M.thermoresistible__bu ARL-----------------------------------------------
MAB_2309c|M.abscessus_ATCC_199 ALLLADLG------------------------------------------
Mb1859|M.bovis_AF2122/97 RHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITL
Rv1828|M.tuberculosis_H37Rv RHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITL
MLBr_02075|M.leprae_Br4923 RHLRAFRSAADRQSDLIVQIAGPIVKAGKAGARDRADDLAREVAALAITL
MAV_3222|M.avium_104 ARRF----------------------------------------------
MUL_0011|M.ulcerans_Agy99 DSEEAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFG
MMAR_2990|M.marinum_M S-------------------------------------------------
Mflv_1922|M.gilvum_PYR-GCK ---------------------
Mvan_4811|M.vanbaalenii_PYR-1 ---------------------
MSMEG_5450|M.smegmatis_MC2_155 ---------------------
TH_0931|M.thermoresistible__bu ---------------------
MAB_2309c|M.abscessus_ATCC_199 ---------------------
Mb1859|M.bovis_AF2122/97 HTSLIKSAVRDVLHR------
Rv1828|M.tuberculosis_H37Rv HTSLIKSAVRDVLHR------
MLBr_02075|M.leprae_Br4923 HTSLIKSAVRGVLHR------
MAV_3222|M.avium_104 ---------------------
MUL_0011|M.ulcerans_Agy99 LPGLAAYCREAIHANANRAGG
MMAR_2990|M.marinum_M ---------------------