For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1969 (-)

annotation: MerR-family protein transcriptional regulator
coordinates: 2050405 - 2050770
length: 121

MKIGELARSTGVSVRSLRYYEQRRLISARRTPGGQRIYDEDAVERVALIKELFAAGISSDGVVQMLPCID
SGTATPAMVERLVCERARIDAEMKRLAATRDRLDQIIVETRRHVRSRAAAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1969--100% (121)MerR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_4397-5e-1541.28% (109) transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_3180-5e-1036.00% (100) transcriptional regulator, MerR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3367-8e-0933.94% (109) MerR family transcriptional regulator
M. gilvum PYR-GCKMflv_3212-5e-1136.11% (108) MerR family transcriptional regulator
M. tuberculosis H37RvRv3334-9e-0933.94% (109) MerR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2246-2e-0940.28% (72) thiol-specific antioxidant related protein/peroxidoxin BcpB
M. marinum MMMAR_2990hspR_23e-0734.67% (75) heat shock protein transcriptional repressor HspR_2
M. avium 104MAV_3222-1e-1036.00% (100) transcriptional regulator, MerR family protein
M. thermoresistible (build 8)TH_0931soxR1e-0731.43% (105) redox-sensitive transcriptional activator SoxR
M. ulcerans Agy99MUL_0596hspR1e-0525.45% (110) heat shock protein transcriptional repressor HspR
M. vanbaalenii PYR-1Mvan_4811-5e-0938.18% (110) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3367|M.bovis_AF2122/97            -----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTA
Rv3334|M.tuberculosis_H37Rv         -----------------MKISEVAALTNTSTKTLRFYENSGLLPPPARTA
Mflv_3212|M.gilvum_PYR-GCK          -----------------MRIGKLAEATGATTATLRYYEDEGLLPPAERSP
TH_0931|M.thermoresistible__bu      -----------MG-AHELTPSEMSARSGVAVSALHFYEREGLIT-SRRTA
Mvan_4811|M.vanbaalenii_PYR-1       -----------MESAHELTPGEMAVRSGVAVSALHFYEREGLIS-SRRTS
MSMEG_1969|M.smegmatis_MC2_155      -----------------MKIGELARSTGVSVRSLRYYEQRRLIS-ARRTP
MMAR_2990|M.marinum_M               MADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLRLYERHGLVT-PARSE
MUL_0596|M.ulcerans_Agy99           MAKNSREG-----EARTFLISVAAELAGMHAQTLRTYDRLGLVS-PRRTS
MAB_2246|M.abscessus_ATCC_1997      -----------------MQISELARRAGVSLKAVRYYERLGLVM-PSRLG
MAV_3222|M.avium_104                ----------------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTRLG
                                                        .  :  :.    ::: *:   *:  . *  

Mb3367|M.bovis_AF2122/97            SGYRNYGPEIVDRLRFIHRG-QAAGLALQEVRQILAIHDRGE-APCAHVR
Rv3334|M.tuberculosis_H37Rv         SGYRNYGPEIVDRLRFIHRG-QAAGLALQEVRQILAIHDRGE-APCAHVR
Mflv_3212|M.gilvum_PYR-GCK          AGYRDYAADTIARVGFIRRG-QAAGFSLAQIRQILDIRDSGH-APCTHVR
TH_0931|M.thermoresistible__bu      GNQRRYPREMLRRVAFIRMS-QRLGIPLARIREALATLPSDRVPTSKDWA
Mvan_4811|M.vanbaalenii_PYR-1       GNQRRYARDTLRRVAFIRMS-QRLGIPLARIREALATLPTDRVPTSKDWA
MSMEG_1969|M.smegmatis_MC2_155      GGQRIYDEDAVERVALIKEL-FAAGISSDGVVQMLPCIDSG--TATPAMV
MMAR_2990|M.marinum_M               GGTRRYSADDLVRLQRVSVL-IEAGINLAGISRILNLEDDNAALAAANCD
MUL_0596|M.ulcerans_Agy99           GGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRIIELTNQVEALQSRLQE
MAB_2246|M.abscessus_ATCC_1997      NGYRDYTDDDLQIVGEIRSL-AAAGISPSLARPFIECLREGHDHSDDCPS
MAV_3222|M.avium_104                -GQRRYDEAVLSRLEVIALC-KTAGFALDEIQRLFADDAPGR----PASR
                                     . * *    :  :  :       *.        :               

Mb3367|M.bovis_AF2122/97            QLLSTRI--DEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWIL
Rv3334|M.tuberculosis_H37Rv         QLLSTRI--DEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWIL
Mflv_3212|M.gilvum_PYR-GCK          DLLDIRL--TDLDEQISALVALRETIARLRQGAESVDPESCSADDVCRYL
TH_0931|M.thermoresistible__bu      ELSAGWR--ADLDERILHLQRLRDNLADCIGCGCLSLKTCALSNPDDALA
Mvan_4811|M.vanbaalenii_PYR-1       RLSAGWR--EDLDQRIVHLQRLRDNLAGCIGCGCLSLKVCALANPGDVLS
MSMEG_1969|M.smegmatis_MC2_155      ERLVCER--ARIDAEMKRLAATRDRLDQIIVETRRHVRSRAAAG------
MMAR_2990|M.marinum_M               LLASNRS--LRDAARAAVRLMNHGRSAENGEGGDTS--------------
MUL_0596|M.ulcerans_Agy99           MADELET--MRAKQRREVALVPRSTALVVWQRAGPAEPAFRHTPPGYGPV
MAB_2246|M.abscessus_ATCC_1997      ALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFTEEPRNMDDYTE
MAV_3222|M.avium_104                ALARAKL--AQIDAQLDSLTRARAVIEWGMRCTCPSIDACTCGIHPTRPA
                                                          .                           

Mb3367|M.bovis_AF2122/97            ESDLDEPTAIEVSDIHA---------------------------------
Rv3334|M.tuberculosis_H37Rv         ESDLDEPTAIEVSDIHA---------------------------------
Mflv_3212|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0931|M.thermoresistible__bu      ARGPGAARL-----------------------------------------
Mvan_4811|M.vanbaalenii_PYR-1       EEGPGPVRL-----------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_2990|M.marinum_M               --------------------------------------------------
MUL_0596|M.ulcerans_Agy99           PVLKNPERLDPVLKKPEM--------------------------------
MAB_2246|M.abscessus_ATCC_1997      LPFGLPVPVDDGAADHLQDRPLPDLTLMATGGCAVRLRGLPEGRTVLYLY
MAV_3222|M.avium_104                PVGPDVRSARRF--------------------------------------
                                                                                      

Mb3367|M.bovis_AF2122/97            --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3212|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0931|M.thermoresistible__bu      --------------------------------------------------
Mvan_4811|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_2990|M.marinum_M               --------------------------------------------------
MUL_0596|M.ulcerans_Agy99           --------------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      PLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSS
MAV_3222|M.avium_104                --------------------------------------------------
                                                                                      

Mb3367|M.bovis_AF2122/97            --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3212|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0931|M.thermoresistible__bu      --------------------------------------------------
Mvan_4811|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1969|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_2990|M.marinum_M               --------------------------------------------------
MUL_0596|M.ulcerans_Agy99           --------------------------------------------------
MAB_2246|M.abscessus_ATCC_1997      QDTDYQAEVVRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITL
MAV_3222|M.avium_104                --------------------------------------------------
                                                                                      

Mb3367|M.bovis_AF2122/97            ----------------------------------
Rv3334|M.tuberculosis_H37Rv         ----------------------------------
Mflv_3212|M.gilvum_PYR-GCK          ----------------------------------
TH_0931|M.thermoresistible__bu      ----------------------------------
Mvan_4811|M.vanbaalenii_PYR-1       ----------------------------------
MSMEG_1969|M.smegmatis_MC2_155      ----------------------------------
MMAR_2990|M.marinum_M               ----------------------------------
MUL_0596|M.ulcerans_Agy99           ----------------------------------
MAB_2246|M.abscessus_ATCC_1997      VVRDGRIEQVFYPIFPPDTHAQQVLEWLTSHPMD
MAV_3222|M.avium_104                ----------------------------------