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MESAHELTPGEMAVRSGVAVSALHFYEREGLISSRRTSGNQRRYARDTLRRVAFIRMSQRLGIPLARIRE ALATLPTDRVPTSKDWARLSAGWREDLDQRIVHLQRLRDNLAGCIGCGCLSLKVCALANPGDVLSEEGPG PVRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4811 | - | - | 100% (144) | MerR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4935 | - | 4e-07 | 29.82% (114) | MerR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1160 | - | 8e-06 | 33.71% (89) | MerR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 5e-05 | 32.81% (64) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1922 | - | 7e-73 | 88.89% (144) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 5e-05 | 32.81% (64) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2309c | - | 7e-34 | 46.76% (139) | putative transcriptional regulator |
| M. marinum M | MMAR_2990 | hspR_2 | 1e-06 | 42.11% (57) | heat shock protein transcriptional repressor HspR_2 |
| M. avium 104 | MAV_3222 | - | 4e-10 | 33.61% (119) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_5450 | soxR | 3e-69 | 87.14% (140) | redox-sensitive transcriptional activator SoxR |
| M. thermoresistible (build 8) | TH_0931 | soxR | 3e-66 | 83.69% (141) | redox-sensitive transcriptional activator SoxR |
| M. ulcerans Agy99 | MUL_0011 | - | 6e-06 | 38.81% (67) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4811|M.vanbaalenii_PYR-1 -----------MESAHELTP-GEMAVRSGVAVSALHFYEREGLISS-RRT
Mflv_1922|M.gilvum_PYR-GCK MCTVTATRVEVMEWPHELTP-GDMAARSGVAVSALHFYEREGLITS-RRT
MSMEG_5450|M.smegmatis_MC2_155 --------------MHELTP-GELAQRSGVAVSALHFYEREGLITS-RRT
TH_0931|M.thermoresistible__bu ------------MGAHELTP-SEMSARSGVAVSALHFYEREGLITS-RRT
MAB_2309c|M.abscessus_ATCC_199 -----------MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPA-ERT
Mb3367|M.bovis_AF2122/97 ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Rv3334|M.tuberculosis_H37Rv ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
MAV_3222|M.avium_104 -----------------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTRL
MUL_0011|M.ulcerans_Agy99 ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
MMAR_2990|M.marinum_M -MADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLRLYERHGLVTP-ARS
. : . :. ::: * **: . *
Mvan_4811|M.vanbaalenii_PYR-1 SGNQRRYARDTLRRVAFIRMSQRLGIPLARIREALAT-------------
Mflv_1922|M.gilvum_PYR-GCK GGNQRRYARETLRRVAFIRMSQRLGIPLARIREALAT-------------
MSMEG_5450|M.smegmatis_MC2_155 SGNQRRYARETLRRVAFIRMSQRLGIPLSRIREALST-------------
TH_0931|M.thermoresistible__bu AGNQRRYPREMLRRVAFIRMSQRLGIPLARIREALAT-------------
MAB_2309c|M.abscessus_ATCC_199 SGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLST-------------
Mb3367|M.bovis_AF2122/97 ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAI-------------
Rv3334|M.tuberculosis_H37Rv ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAI-------------
MAV_3222|M.avium_104 GG-QRRYDEAVLSRLEVIALCKTAGFALDEIQRLFA--------------
MUL_0011|M.ulcerans_Agy99 ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRER
MMAR_2990|M.marinum_M EGGTRRYSADDLVRLQRVSVLIEAGINLAGISRILNL-------------
. * : : *: : : * : . :
Mvan_4811|M.vanbaalenii_PYR-1 ----------------------------------------LPTDRVPTSK
Mflv_1922|M.gilvum_PYR-GCK ----------------------------------------LPSDRVPTSK
MSMEG_5450|M.smegmatis_MC2_155 ----------------------------------------LPNDRVPTSK
TH_0931|M.thermoresistible__bu ----------------------------------------LPSDRVPTSK
MAB_2309c|M.abscessus_ATCC_199 ----------------------------------------LPDYRAPSTR
Mb3367|M.bovis_AF2122/97 ----------------------------------------HDRGEAPCAH
Rv3334|M.tuberculosis_H37Rv ----------------------------------------HDRGEAPCAH
MAV_3222|M.avium_104 -------------------------------------------DDAPGRP
MUL_0011|M.ulcerans_Agy99 VMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQ
MMAR_2990|M.marinum_M ------------------------------------------------ED
Mvan_4811|M.vanbaalenii_PYR-1 DWARLSAGWREDLDQR---IVHLQRLRDNLAGCIGCGCLSLKVCALANPG
Mflv_1922|M.gilvum_PYR-GCK DWARLSAGWRDDLDQR---ILHLERLRDNLAGCIGCGCLSLKICALANPG
MSMEG_5450|M.smegmatis_MC2_155 DWARLSAGWRQDLDDR---IMHLQRLRDNLTGCIGCGCLSLKTCQLTNPG
TH_0931|M.thermoresistible__bu DWAELSAGWRADLDER---ILHLQRLRDNLADCIGCGCLSLKTCALSNPD
MAB_2309c|M.abscessus_ATCC_199 DWQRISRRWHAHLEAR---KNAIADMQEKLTGCIGCGCLSMTKCALFNPA
Mb3367|M.bovis_AF2122/97 VRQLLST-RIDEVRAQ---IAELIALEGHLQTLLDHASYGPPTEHDHSTV
Rv3334|M.tuberculosis_H37Rv VRQLLST-RIDEVRAQ---IAELIALEGHLQTLLDHASYGPPTEHDHSTV
MAV_3222|M.avium_104 ASRALARAKLAQIDAQ---LDSLTRARAVIEWGMRCTCPSIDACTCGIHP
MUL_0011|M.ulcerans_Agy99 KWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSE
MMAR_2990|M.marinum_M DNAALAAANCDLLASN-------RSLRDAARAAVRLMNHGRSAENGEGGD
: . . .
Mvan_4811|M.vanbaalenii_PYR-1 DVLSE---EGPGPVRL----------------------------------
Mflv_1922|M.gilvum_PYR-GCK DVLAD---EGPGAARL----------------------------------
MSMEG_5450|M.smegmatis_MC2_155 DVLAE---RGPGAARL----------------------------------
TH_0931|M.thermoresistible__bu DALAA---RGPGAARL----------------------------------
MAB_2309c|M.abscessus_ATCC_199 DILAD---DGSTGALLLADLG-----------------------------
Mb3367|M.bovis_AF2122/97 CWILESDLDEPTAIEVSDIHA-----------------------------
Rv3334|M.tuberculosis_H37Rv CWILESDLDEPTAIEVSDIHA-----------------------------
MAV_3222|M.avium_104 TRPAPVGPDVRSARRF----------------------------------
MUL_0011|M.ulcerans_Agy99 EAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPG
MMAR_2990|M.marinum_M TS------------------------------------------------
Mvan_4811|M.vanbaalenii_PYR-1 ------------------
Mflv_1922|M.gilvum_PYR-GCK ------------------
MSMEG_5450|M.smegmatis_MC2_155 ------------------
TH_0931|M.thermoresistible__bu ------------------
MAB_2309c|M.abscessus_ATCC_199 ------------------
Mb3367|M.bovis_AF2122/97 ------------------
Rv3334|M.tuberculosis_H37Rv ------------------
MAV_3222|M.avium_104 ------------------
MUL_0011|M.ulcerans_Agy99 LAAYCREAIHANANRAGG
MMAR_2990|M.marinum_M ------------------