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M. avium 104 MAV_3222 (-)

annotation: transcriptional regulator, MerR family protein
coordinates: 3320857 - 3321273
length: 138

LTIGEVARRSGVAATTLRYYEQIGLLPAPTRLGGQRRYDEAVLSRLEVIALCKTAGFALDEIQRLFADDA
PGRPASRALARAKLAQIDAQLDSLTRARAVIEWGMRCTCPSIDACTCGIHPTRPAPVGPDVRSARRF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3222--100% (138)transcriptional regulator, MerR family protein
M. avium 104MAV_1646-5e-0735.05% (97) transcriptional regulator, MerR family protein
M. avium 104MAV_4105-2e-0538.46% (65) transcriptional regulator, MerR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3367-6e-0934.69% (98) MerR family transcriptional regulator
M. gilvum PYR-GCKMflv_1922-1e-0932.77% (119) MerR family transcriptional regulator
M. tuberculosis H37RvRv3334-7e-0934.69% (98) MerR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2309c-5e-1130.00% (120) putative transcriptional regulator
M. marinum MMMAR_0009-2e-0832.43% (111) transcriptional regulator
M. smegmatis MC2 155MSMEG_3180-7e-5274.40% (125) transcriptional regulator, MerR family protein
M. thermoresistible (build 8)TH_0931soxR1e-0930.08% (133) redox-sensitive transcriptional activator SoxR
M. ulcerans Agy99MUL_0011-1e-0832.43% (111) transcriptional regulator
M. vanbaalenii PYR-1Mvan_4691-1e-1330.00% (150) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MAV_3222|M.avium_104                -----------------MLTIGEVARRSGVAATTLRYYEQIG-LLPAPTR
MSMEG_3180|M.smegmatis_MC2_155      --------------MAAHLTIGEVARRAGVAPTALRYYEKLG-LLPAPER
MMAR_0009|M.marinum_M               ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
MUL_0011|M.ulcerans_Agy99           ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
Mflv_1922|M.gilvum_PYR-GCK          MCTVTATRVEVMEWPHELTP-GDMAARSGVAVSALHFYEREG-LITSRRT
TH_0931|M.thermoresistible__bu      MG------------AHELTP-SEMSARSGVAVSALHFYEREG-LITSRRT
MAB_2309c|M.abscessus_ATCC_199      MKG-----------KTELLPIGEVARRSGIAVSAVRYYADIG-LVPAERT
Mb3367|M.bovis_AF2122/97            ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Rv3334|M.tuberculosis_H37Rv         ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Mvan_4691|M.vanbaalenii_PYR-1       -----------------MIDISAVARRSGLPTSTLRFYEEKGLIASVGRR
                                                         . ::   . .  :::.*   * : .    

MAV_3222|M.avium_104                LGGQRRYDEAVLSRLEVIALCKTAGFALDEIQRLFAD-------------
MSMEG_3180|M.smegmatis_MC2_155      IGGRRRYDEAILVRLEVIRLCKAAGFSLDEIAVLMDD-------------
MMAR_0009|M.marinum_M               ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRER
MUL_0011|M.ulcerans_Agy99           ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRER
Mflv_1922|M.gilvum_PYR-GCK          GGNQRRYARETLRRVAFIRMSQRLGIPLARIREALAT-------------
TH_0931|M.thermoresistible__bu      AGNQRRYPREMLRRVAFIRMSQRLGIPLARIREALAT-------------
MAB_2309c|M.abscessus_ATCC_199      SGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLST-------------
Mb3367|M.bovis_AF2122/97            ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD-----------
Rv3334|M.tuberculosis_H37Rv         ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD-----------
Mvan_4691|M.vanbaalenii_PYR-1       SR-RRLFGPDVFDRLALITLGRAAGFSLDEIATMLTLG------------
                                        * :    . *:  :       :.* .:   :               

MAV_3222|M.avium_104                ------------------------------------DAPGRPASRALAR-
MSMEG_3180|M.smegmatis_MC2_155      ------------------------------------DTPGRPVARALAE-
MMAR_0009|M.marinum_M               VMARLDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAETEQ
MUL_0011|M.ulcerans_Agy99           VMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQ
Mflv_1922|M.gilvum_PYR-GCK          ----------------------------------------LPSDRVPTSK
TH_0931|M.thermoresistible__bu      ----------------------------------------LPSDRVPTSK
MAB_2309c|M.abscessus_ATCC_199      ----------------------------------------LPDYRAPSTR
Mb3367|M.bovis_AF2122/97            -------------------------------------RGEAPCAHVRQLL
Rv3334|M.tuberculosis_H37Rv         -------------------------------------RGEAPCAHVRQLL
Mvan_4691|M.vanbaalenii_PYR-1       ----------------------------------------GPRQIDRKAL
                                                                                      

MAV_3222|M.avium_104                ---------------------------------------AKLAQIDAQLD
MSMEG_3180|M.smegmatis_MC2_155      ---------------------------------------AKLAEIDAQIA
MMAR_0009|M.marinum_M               KWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPADSE
MUL_0011|M.ulcerans_Agy99           KWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSE
Mflv_1922|M.gilvum_PYR-GCK          DWAR--------------------------------LSAGWRDDLDQRIL
TH_0931|M.thermoresistible__bu      DWAE--------------------------------LSAGWRADLDERIL
MAB_2309c|M.abscessus_ATCC_199      DWQR--------------------------------ISRRWHAHLEARKN
Mb3367|M.bovis_AF2122/97            S--------------------------------------TRIDEVRAQIA
Rv3334|M.tuberculosis_H37Rv         S--------------------------------------TRIDEVRAQIA
Mvan_4691|M.vanbaalenii_PYR-1       T--------------------------------------TRAAEIDSTIE
                                                                                :     

MAV_3222|M.avium_104                SLTRARAVIEWGMRCTCPSIDACTCGIH---------PTRPAPVGPDVRS
MSMEG_3180|M.smegmatis_MC2_155      SLARARSIVEWGMQCTCPSIDECTCGIH---------RTVPA--------
MMAR_0009|M.marinum_M               EAMNAAEQHRRHVNRWFYDCPPAFHRSL---------GDMYVSDPRYIAT
MUL_0011|M.ulcerans_Agy99           EAMNAAEQHRRHVNRWFYDCPPAFHRNL---------GDMYVSDPRYIAT
Mflv_1922|M.gilvum_PYR-GCK          HLERLRDNLAGCIGCGCLSLKICALANP---------GDVLADEGPGAAR
TH_0931|M.thermoresistible__bu      HLQRLRDNLADCIGCGCLSLKTCALSNP---------DDALAARGPGAAR
MAB_2309c|M.abscessus_ATCC_199      AIADMQEKLTGCIGCGCLSMTKCALFNP---------ADILADDGSTGAL
Mb3367|M.bovis_AF2122/97            ELIALEGHLQTLLDHASYGPPTEHDHS----------TVCWILES----D
Rv3334|M.tuberculosis_H37Rv         ELIALEGHLQTLLDHASYGPPTEHDHS----------TVCWILES----D
Mvan_4691|M.vanbaalenii_PYR-1       RLTAIS----TALKHAAACPAPDHMECPTFRGYLDLAAAGLFSESPPRKS
                                                :                                     

MAV_3222|M.avium_104                ARRF-----------------------
MSMEG_3180|M.smegmatis_MC2_155      ---------------------------
MMAR_0009|M.marinum_M               YDESFGLPGLAAYCREAIHANANRTGG
MUL_0011|M.ulcerans_Agy99           YDESFGLPGLAAYCREAIHANANRAGG
Mflv_1922|M.gilvum_PYR-GCK          L--------------------------
TH_0931|M.thermoresistible__bu      L--------------------------
MAB_2309c|M.abscessus_ATCC_199      LLADLG---------------------
Mb3367|M.bovis_AF2122/97            LDEPTAIEVSDIHA-------------
Rv3334|M.tuberculosis_H37Rv         LDEPTAIEVSDIHA-------------
Mvan_4691|M.vanbaalenii_PYR-1       PPKPTIKKQVRLGAGQPIRGE------