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MAAHLTIGEVARRAGVAPTALRYYEKLGLLPAPERIGGRRRYDEAILVRLEVIRLCKAAGFSLDEIAVLM DDDTPGRPVARALAEAKLAEIDAQIASLARARSIVEWGMQCTCPSIDECTCGIHRTVPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3180 | - | - | 100% (129) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_5450 | soxR | 7e-11 | 32.77% (119) | redox-sensitive transcriptional activator SoxR |
| M. smegmatis MC2 155 | MSMEG_1969 | - | 6e-10 | 36.00% (100) | MerR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 6e-09 | 38.78% (98) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3212 | - | 2e-10 | 36.89% (103) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 6e-09 | 38.78% (98) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2309c | - | 5e-11 | 31.93% (119) | putative transcriptional regulator |
| M. marinum M | MMAR_0009 | - | 2e-07 | 39.13% (69) | transcriptional regulator |
| M. avium 104 | MAV_3222 | - | 5e-52 | 74.40% (125) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_0931 | soxR | 2e-11 | 33.06% (124) | redox-sensitive transcriptional activator SoxR |
| M. ulcerans Agy99 | MUL_0011 | - | 1e-07 | 39.13% (69) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4691 | - | 6e-14 | 36.52% (115) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3367|M.bovis_AF2122/97 -------MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEI
Rv3334|M.tuberculosis_H37Rv -------MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEI
Mflv_3212|M.gilvum_PYR-GCK -------MRIGKLAEATGATTATLRYYEDEGLLPPAERSPAGYRDYAADT
MSMEG_3180|M.smegmatis_MC2_155 ---MAAHLTIGEVARRAGVAPTALRYYEKLGLLPAPERI-GGRRRYDEAI
MAV_3222|M.avium_104 ------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTRL-GGQRRYDEAV
Mvan_4691|M.vanbaalenii_PYR-1 ------MIDISAVARRSGLPTSTLRFYEEKGLIASVGRR-SRRRLFGPDV
MAB_2309c|M.abscessus_ATCC_199 MKGKTELLPIGEVARRSGIAVSAVRYYADIG-LVPAERTSGNVRVFRRHA
TH_0931|M.thermoresistible__bu -MGAHELTPS-EMSARSGVAVSALHFYEREG-LITSRRTAGNQRRYPREM
MMAR_0009|M.marinum_M ----MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAASGYRVYTSAD
MUL_0011|M.ulcerans_Agy99 ----MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAASGYRVYTSAD
:: . . :::.* * : . * . * :
Mb3367|M.bovis_AF2122/97 VDRLRFIHRGQAAGLALQEVRQILAI------------------------
Rv3334|M.tuberculosis_H37Rv VDRLRFIHRGQAAGLALQEVRQILAI------------------------
Mflv_3212|M.gilvum_PYR-GCK IARVGFIRRGQAAGFSLAQIRQILDI------------------------
MSMEG_3180|M.smegmatis_MC2_155 LVRLEVIRLCKAAGFSLDEIAVLMDD------------------------
MAV_3222|M.avium_104 LSRLEVIALCKTAGFALDEIQRLFAD------------------------
Mvan_4691|M.vanbaalenii_PYR-1 FDRLALITLGRAAGFSLDEIATMLTL------------------------
MAB_2309c|M.abscessus_ATCC_199 LRRISLIRVATGFGIPLSEVAEVLST------------------------
TH_0931|M.thermoresistible__bu LRRVAFIRMSQRLGIPLARIREALAT------------------------
MMAR_0009|M.marinum_M LTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRERVMARLDEMKDL
MUL_0011|M.ulcerans_Agy99 LTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRERVMARLDEMKDL
. *: : :.* .: :
Mb3367|M.bovis_AF2122/97 -------------------------------HDRGEAPCAHVR-------
Rv3334|M.tuberculosis_H37Rv -------------------------------HDRGEAPCAHVR-------
Mflv_3212|M.gilvum_PYR-GCK -------------------------------RDSGHAPCTHVR-------
MSMEG_3180|M.smegmatis_MC2_155 -------------------------------DTPG---RPVAR-------
MAV_3222|M.avium_104 -------------------------------DAPG---RPASR-------
Mvan_4691|M.vanbaalenii_PYR-1 -------------------------------GGP----RQIDR-------
MAB_2309c|M.abscessus_ATCC_199 -----------------------------LPDYRAPSTRDWQR-------
TH_0931|M.thermoresistible__bu -----------------------------LPSDRVPTSKDWAE-------
MMAR_0009|M.marinum_M VEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAETEQKWGETTEWKES
MUL_0011|M.ulcerans_Agy99 VEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQKWGETAEWKES
.
Mb3367|M.bovis_AF2122/97 ------------------------QLLSTRIDEVRAQIAELIALEGHLQT
Rv3334|M.tuberculosis_H37Rv ------------------------QLLSTRIDEVRAQIAELIALEGHLQT
Mflv_3212|M.gilvum_PYR-GCK ------------------------DLLDIRLTDLDEQISALVALRETIAR
MSMEG_3180|M.smegmatis_MC2_155 ------------------------ALAEAKLAEIDAQIASLARARSIVEW
MAV_3222|M.avium_104 ------------------------ALARAKLAQIDAQLDSLTRARAVIEW
Mvan_4691|M.vanbaalenii_PYR-1 ------------------------KALTTRAAEIDSTIERLTAISTALKH
MAB_2309c|M.abscessus_ATCC_199 -------------------------ISRRWHAHLEARKNAIADMQEKLTG
TH_0931|M.thermoresistible__bu -------------------------LSAGWRADLDERILHLQRLRDNLAD
MMAR_0009|M.marinum_M QRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPADSEEAMNAAEQHRR
MUL_0011|M.ulcerans_Agy99 QRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSEEAMNAAEQHRR
:
Mb3367|M.bovis_AF2122/97 LLDHASYGPPTE------HDHSTVCWILESDLDEPTAIEVSDIHA-----
Rv3334|M.tuberculosis_H37Rv LLDHASYGPPTE------HDHSTVCWILESDLDEPTAIEVSDIHA-----
Mflv_3212|M.gilvum_PYR-GCK LRQGAESVDPES------CSADDVCRYL----------------------
MSMEG_3180|M.smegmatis_MC2_155 GMQCTCPS----------IDECTCGIHRTVPA------------------
MAV_3222|M.avium_104 GMRCTCPS----------IDACTCGIHPTRPAPVGPDVRSARRF------
Mvan_4691|M.vanbaalenii_PYR-1 AAACPAPDHMECPTFRGYLDLAAAGLFSESPPRKSPPKPTIKKQVRLGAG
MAB_2309c|M.abscessus_ATCC_199 CIGCGCLSMTKC------ALFNPADILADDGSTGALLLADLG--------
TH_0931|M.thermoresistible__bu CIGCGCLSLKTC------ALSNPDDALAARGPGAARL-------------
MMAR_0009|M.marinum_M HVNRWFYDCPPA------FHRSLGDMYVSDPRYIATYDESFGLPGLAAYC
MUL_0011|M.ulcerans_Agy99 HVNRWFYDCPPA------FHRNLGDMYVSDPRYIATYDESFGLPGLAAYC
Mb3367|M.bovis_AF2122/97 -------------
Rv3334|M.tuberculosis_H37Rv -------------
Mflv_3212|M.gilvum_PYR-GCK -------------
MSMEG_3180|M.smegmatis_MC2_155 -------------
MAV_3222|M.avium_104 -------------
Mvan_4691|M.vanbaalenii_PYR-1 QPIRGE-------
MAB_2309c|M.abscessus_ATCC_199 -------------
TH_0931|M.thermoresistible__bu -------------
MMAR_0009|M.marinum_M REAIHANANRTGG
MUL_0011|M.ulcerans_Agy99 REAIHANANRAGG