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DGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRAASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLD EGNAVSHLVRQRERVMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQKWGETA EWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSEEAMNAAEQHRRHVNRWFYDCPPAFHR NLGDMYVSDPRYIATYDESFGLPGLAAYCREAIHANANRAGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0011 | - | - | 100% (253) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_0596 | hspR | 5e-05 | 33.33% (96) | heat shock protein transcriptional repressor HspR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 8e-06 | 32.38% (105) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0148 | - | 1e-124 | 82.87% (251) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 8e-06 | 32.38% (105) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2309c | - | 1e-06 | 37.31% (67) | putative transcriptional regulator |
| M. marinum M | MMAR_0009 | - | 1e-143 | 96.84% (253) | transcriptional regulator |
| M. avium 104 | MAV_3222 | - | 3e-08 | 32.43% (111) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_2194 | - | 1e-119 | 80.63% (253) | MerR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2460 | - | 2e-07 | 30.77% (91) | PUTATIVE putative transcriptional regulator, MerR family |
| M. vanbaalenii PYR-1 | Mvan_1919 | - | 1e-132 | 88.89% (252) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3367|M.bovis_AF2122/97 ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Rv3334|M.tuberculosis_H37Rv ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
MUL_0011|M.ulcerans_Agy99 ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
MMAR_0009|M.marinum_M ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
Mvan_1919|M.vanbaalenii_PYR-1 MTSGTTLTYVTQEMQVDELTVGEVAERFGITVRTLHHYDEIGLLTPGRRC
Mflv_0148|M.gilvum_PYR-GCK ---------MTQETRMEELTVGEVAKRFGITIRTLHHYDHIGLLTPEQRN
MSMEG_2194|M.smegmatis_MC2_155 ---------------MEELTVGEVAKRFRITVRTLHHYDEIGLLSPSRRV
TH_2460|M.thermoresistible__bu -----------------------------------------------VRT
MAV_3222|M.avium_104 -----------------MLTIGEVARRSGVAATTLRYYEQIGLLPAPTR-
MAB_2309c|M.abscessus_ATCC_199 -----------MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVP-AERT
*
Mb3367|M.bovis_AF2122/97 ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILA-IHD----------
Rv3334|M.tuberculosis_H37Rv ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILA-IHD----------
MUL_0011|M.ulcerans_Agy99 ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLD-EGNAVSHLVRQRE
MMAR_0009|M.marinum_M ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLD-EGNAVSHLVRQRE
Mvan_1919|M.vanbaalenii_PYR-1 ASGYRVYTPADLTRLSQVIVYRRLDFSLDEIASLLD-EGNEVSHLIRQRE
Mflv_0148|M.gilvum_PYR-GCK ASGYRVYTSADLTRLSQIIVYRRLEMSLDEIASVLD-EGDEISHLRRQRE
MSMEG_2194|M.smegmatis_MC2_155 TSGYRVYTPADLTRLSQIIVYRRLEFSLDEIASLLD-EGDAVSHLLRQRE
TH_2460|M.thermoresistible__bu AAGYRGDTDAAIERLHLIPVYRSAGLPLEEIRALLDGAADPLARLQRQHA
MAV_3222|M.avium_104 LGGQRRYDEAVLSRLEVIALCKTAGFALDEIQRLFA---DDAPGRPASRA
MAB_2309c|M.abscessus_ATCC_199 SGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLSTLPDYRAPSTRDWQ
.. * : *: : :.*.*: :: :
Mb3367|M.bovis_AF2122/97 RGEAP-CAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDH--ASYGPPT
Rv3334|M.tuberculosis_H37Rv RGEAP-CAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDH--ASYGPPT
MUL_0011|M.ulcerans_Agy99 RVMAR-LDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVET
MMAR_0009|M.marinum_M RVMAR-LDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAET
Mvan_1919|M.vanbaalenii_PYR-1 RVMSR-LDEMKDLVAAIDQALEKAMTNTPMTDDDMRELFGDGFDDYQAEA
Mflv_0148|M.gilvum_PYR-GCK RVMSR-LDELTELVGAIDQALENAMTNTPMTDDDMRELFGDSFDDYQAEA
MSMEG_2194|M.smegmatis_MC2_155 RVMAR-LGEMKDLVAAIDQALEKAMTNTPMTDDDMRELFGEGFDDYQAEA
TH_2460|M.thermoresistible__bu LLLEQ-ADRLQHTIKAVEELMNAHRHGIQLSAEEQVEIFGS--AVFR---
MAV_3222|M.avium_104 LARAK-LAQIDAQLDSLTRARAVIEWGMRCTCPSIDACTCGIHPTRPAPV
MAB_2309c|M.abscessus_ATCC_199 RISRRWHAHLEARKNAIADMQEKLTGCIGCGCLSMTKCALFNPADILADD
.: :
Mb3367|M.bovis_AF2122/97 EHDHSTVCWILES----------------------------------DLD
Rv3334|M.tuberculosis_H37Rv EHDHSTVCWILES----------------------------------DLD
MUL_0011|M.ulcerans_Agy99 EQKWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPAD
MMAR_0009|M.marinum_M EQKWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPAD
Mvan_1919|M.vanbaalenii_PYR-1 EQKWGETAEWKESQRRTKSYGKDEWVQIKSEGEAVEKALSDAFRAGLPPD
Mflv_0148|M.gilvum_PYR-GCK EQKWGETAEWKESQRRATSYGKDDWVRIKAEGQAVEKALADAFRAGLPAD
MSMEG_2194|M.smegmatis_MC2_155 ERKFGDTAEWKESQRRTKSYSKGQWIQLKDEGEAVEKALADAFRGGLAPD
TH_2460|M.thermoresistible__bu --------------------------------------------------
MAV_3222|M.avium_104 GPDVRSARRF----------------------------------------
MAB_2309c|M.abscessus_ATCC_199 GSTGALLLADLG--------------------------------------
Mb3367|M.bovis_AF2122/97 EPTAIEVSDIHA--------------------------------------
Rv3334|M.tuberculosis_H37Rv EPTAIEVSDIHA--------------------------------------
MUL_0011|M.ulcerans_Agy99 SEEAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGL
MMAR_0009|M.marinum_M SEEAMNAAEQHRRHVNRWFYDCPPAFHRSLGDMYVSDPRYIATYDESFGL
Mvan_1919|M.vanbaalenii_PYR-1 SAEAMNAAEQHRLHVNRWFYDCPPAFHRKLGDMYVSDPRYVATYDESFGL
Mflv_0148|M.gilvum_PYR-GCK SEEAMNAAEQHRHHVNRWFYDCPPAFHRTLGDMYVSDPRYVATYDESFGL
MSMEG_2194|M.smegmatis_MC2_155 SEVAMDAAEQHRLHVNRWFYDCPPDFHRKLGDMYVSDPAYVARYDESFGL
TH_2460|M.thermoresistible__bu --------------------------------------------------
MAV_3222|M.avium_104 --------------------------------------------------
MAB_2309c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3367|M.bovis_AF2122/97 ------------------------
Rv3334|M.tuberculosis_H37Rv ------------------------
MUL_0011|M.ulcerans_Agy99 PGLAAYCREAIHANANRAGG----
MMAR_0009|M.marinum_M PGLAAYCREAIHANANRTGG----
Mvan_1919|M.vanbaalenii_PYR-1 PGLAAYCREAIHANADRAGQ----
Mflv_0148|M.gilvum_PYR-GCK PGLARYCRDAIHANADRS------
MSMEG_2194|M.smegmatis_MC2_155 PGLAAFCRDAIHANADRAGGDVTG
TH_2460|M.thermoresistible__bu ------------------------
MAV_3222|M.avium_104 ------------------------
MAB_2309c|M.abscessus_ATCC_199 ------------------------