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ADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLRLYERHGLVTPARSEGGTRRYSADDLVRLQRVSVLIE AGINLAGISRILNLEDDNAALAAANCDLLASNRSLRDAARAAVRLMNHGRSAENGEGGDTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2990 | hspR_2 | - | 100% (132) | heat shock protein transcriptional repressor HspR_2 |
| M. marinum M | MMAR_0640 | hspR | 2e-14 | 43.43% (99) | heat shock protein transcriptional repressor HspR |
| M. marinum M | MMAR_3703 | - | 3e-05 | 26.74% (86) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0361 | hspR | 2e-13 | 42.42% (99) | HEAT shock protein transcriptional regulator HspR |
| M. gilvum PYR-GCK | Mflv_0257 | - | 6e-14 | 42.72% (103) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0353 | hspR | 2e-13 | 42.42% (99) | HEAT shock protein transcriptional repressor HspR |
| M. leprae Br4923 | MLBr_02493 | hspR | 1e-13 | 50.00% (74) | heat shock regulator |
| M. abscessus ATCC 19977 | MAB_3468 | - | 3e-30 | 67.05% (88) | MerR family transcriptional regulator |
| M. avium 104 | MAV_4105 | - | 5e-45 | 76.11% (113) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_0713 | - | 8e-15 | 46.88% (96) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_2359 | hspR | 8e-14 | 43.43% (99) | PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR |
| M. ulcerans Agy99 | MUL_0596 | hspR | 2e-14 | 43.43% (99) | heat shock protein transcriptional repressor HspR |
| M. vanbaalenii PYR-1 | Mvan_0637 | - | 2e-14 | 44.86% (107) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0257|M.gilvum_PYR-GCK -----------------MSG-----RKEEARTFLISVAAELAGMHAQTLR
Mvan_0637|M.vanbaalenii_PYR-1 -----------------MSAGRPS-RKEDARTFLISVAAELAGMHAQTLR
MSMEG_0713|M.smegmatis_MC2_155 -----------------MSG---K-RNEEARTFLISVAAELAGMHAQTLR
TH_2359|M.thermoresistible__bu -----------------VSRSK-R-SNDDTRTFMISVAAELAGMHAQTLR
Mb0361|M.bovis_AF2122/97 -----------------MAKNPKD---GESRTFLISVAAELAGMHAQTLR
Rv0353|M.tuberculosis_H37Rv -----------------MAKNPKD---GESRTFLISVAAELAGMHAQTLR
MUL_0596|M.ulcerans_Agy99 -----------------MAKNSRE---GEARTFLISVAAELAGMHAQTLR
MLBr_02493|M.leprae_Br4923 ----------------MMTRNSRDPRQQESRTFLISAAAELAGMHAQTLR
MMAR_2990|M.marinum_M ---------------MADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLR
MAV_4105|M.avium_104 ---------------MADRRGNAGAPASDQGVYGISVAAELSGIAVQSLR
MAB_3468|M.abscessus_ATCC_1997 MVPEDVLYPSGSPVPRLEGPRPPELPAPEKGVYGISVAAELSGAATQSLR
: .: **.:***:* .*:**
Mflv_0257|M.gilvum_PYR-GCK TYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRIIE
Mvan_0637|M.vanbaalenii_PYR-1 TYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRIIE
MSMEG_0713|M.smegmatis_MC2_155 TYDRLGLVTPQRTSGGGRRYSERDVDLLREVQRLSQDEGVNLAGIKRIIE
TH_2359|M.thermoresistible__bu TYDRLGLVRPKRSPGGGRRYSWRDVELLREVQRLSQDEGVNLAGIKRIIE
Mb0361|M.bovis_AF2122/97 TYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIE
Rv0353|M.tuberculosis_H37Rv TYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIE
MUL_0596|M.ulcerans_Agy99 TYDRLGLVSPRRTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRIIE
MLBr_02493|M.leprae_Br4923 TYDRLGLVSPSRASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRIIE
MMAR_2990|M.marinum_M LYERHGLVTPARSEGGTRRYSADDLVRLQRVSVLIE-AGINLAGISRILN
MAV_4105|M.avium_104 LYERHGLVTPARSQGGTRRYSADDLARLKRISKLVD-AGVNLAGVARILA
MAB_3468|M.abscessus_ATCC_1997 LWERHGLLAPSRTEGGTRRYSPEDLIRIRRITTLVA-AGVNIAGIAFILE
::* **: * *: ** **** *: ::.: * *:*:**: *:
Mflv_0257|M.gilvum_PYR-GCK LTNQVEALQSRVRELTNEVEHLRSQPR------PKSTALVVWQ-------
Mvan_0637|M.vanbaalenii_PYR-1 LTNQVEALQARVRELSDEVERLRAQPR------PKSTALVVWQ-------
MSMEG_0713|M.smegmatis_MC2_155 LTNQVDALQRRVAELTAEVERLR---K------P-STALVLWQ-------
TH_2359|M.thermoresistible__bu LTNQVEQLQARVKELTQELEQMRSVPRRELAVVPKSTAVVLWK-------
Mb0361|M.bovis_AF2122/97 LTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK-------
Rv0353|M.tuberculosis_H37Rv LTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK-------
MUL_0596|M.ulcerans_Agy99 LTNQVEALQSRLQEMADELETMRAKQRREVALVPRSTALVVWQRAGPAEP
MLBr_02493|M.leprae_Br4923 LTNQVEALQLKLQELTDELVMLRANQRRDLAVVPKSTALVLWQ-------
MMAR_2990|M.marinum_M LEDDNAALAAANCDLLASNRSLRDAARAAVRLMNHGRSAENGEGGDTS--
MAV_4105|M.avium_104 LEDDNATLSAANTDLRSTNRALREAAKTAD-----G-DAATG--------
MAB_3468|M.abscessus_ATCC_1997 LEDDNTALRAAVYDQ---QRRHSDTDR-----------------------
* .: * : :
Mflv_0257|M.gilvum_PYR-GCK -----------------PRHQR--------
Mvan_0637|M.vanbaalenii_PYR-1 -----------------PRNQR--------
MSMEG_0713|M.smegmatis_MC2_155 -----------------PRNNRKR------
TH_2359|M.thermoresistible__bu -----------------PRRSGEKT-----
Mb0361|M.bovis_AF2122/97 -----------------PRR----------
Rv0353|M.tuberculosis_H37Rv -----------------PRR----------
MUL_0596|M.ulcerans_Agy99 AFRHTPPGYGPVPVLKNPERLDPVLKKPEM
MLBr_02493|M.leprae_Br4923 -----------------PRKPR--------
MMAR_2990|M.marinum_M ------------------------------
MAV_4105|M.avium_104 ------------------------------
MAB_3468|M.abscessus_ATCC_1997 ------------------------------