For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPTMTAIGSFAALPVDDPDSLQDITIEVPELRPHDVLVRVEAVSVNPVDIKRRRSLSPSAEPTILGFDAA GVVEAVGSEVTTLSVGDEVWYAGDVSRPGTNAQLHAVDERIVARKPRSLSFRDAAALPLTTITAWETLFE RFNLTADSRGDLLVLGAAGGVGSVMIQLAKKLTGVRVIATASRDESRQWARDLGADEVIDHHDLRTQALD VAPDGVDYLFTPFSAGNVDVFADIVRPFGHITAIDEPEGLDLVGLKTKSIAWHWELMFTRPLTGYDIAAQ QRLLADAADLVDRGELRTTLTTAIDGFTAANLREAHRMVESGRMVGKVVVSR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5164 | - | - | 100% (332) | zinc-binding alcohol dehydrogenase family protein |
M. smegmatis MC2 155 | MSMEG_4146 | - | 6e-22 | 30.72% (319) | quinone oxidoreductase |
M. smegmatis MC2 155 | MSMEG_5762 | - | 1e-21 | 32.48% (234) | zinc-binding oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3806 | - | 7e-21 | 30.00% (320) | putative oxidoreductase |
M. gilvum PYR-GCK | Mflv_2124 | - | 3e-32 | 33.94% (327) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv3777 | - | 2e-20 | 29.69% (320) | oxidoreductase |
M. leprae Br4923 | MLBr_00118 | - | 3e-20 | 29.34% (317) | putative oxidireductase |
M. abscessus ATCC 19977 | MAB_0207c | - | 1e-25 | 31.58% (342) | quinone oxidoreductase |
M. marinum M | MMAR_2950 | - | 4e-25 | 32.83% (329) | oxidoreductase |
M. avium 104 | MAV_3108 | - | 1e-22 | 32.42% (330) | erythronolide synthase, modules 3 and 4 |
M. thermoresistible (build 8) | TH_1665 | - | 1e-17 | 27.36% (318) | PROBABLE OXIDOREDUCTASE |
M. ulcerans Agy99 | MUL_2209 | - | 2e-25 | 32.83% (329) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_5758 | - | 9e-36 | 37.58% (314) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment MAV_3108|M.avium_104 MPGTEQHLDYLKRLTADLRRTRRRVAELEGRLSEPVAVVGMACRYAGGVD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 SPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMYTRQGSFLQ Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 HAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDPSALRGTAT Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 GVFAGVIHAGYGGEVKGELEGYGLTGSTLSVTSGRVSYVLGLEGPAVSVD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 TACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALAP Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 DGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVWAVLRGSAVNQD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 GASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGTGTVLGDPIEA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 QALLATYGQDRPADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQALRHGVM Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 PKTMHVDVPSPHVDWSAGAVSLLTDPRPWPEHGGPRRAGVSSFGISGTNA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 HVIVEQAPAAAETEAAPASSTMPDAVVPWVVSARSAEALAGQARRLLDHV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 TADAQASPLDVGWSLVSTRAVFEHRAVVVGRERGALATGLAGLASGRPGP Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 ATVVGRARSTGKTVLVFPGQGSQTLGMGRQLYERFEVFAGALDEAVAVVD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 EHSRLSVREVMWGADPELLQSTEFAQPALFVFEVALAALWESLGVTPDVV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 MGHSVGEIAAACVAGVLSLRDAARLVAARGALMAALPPGGVMVAVTAGES Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 QVGPLLGGGVSIAAVNGPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVS Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 HAFHSALMEPMLDGFAAAAAGIEPRPPRIPLVSNLTGQLAGPGYGTPQYW Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 VDHVRRPVRFVDGVRLAESQGAGVFLEVGPGAALTSAVEQSLTSDRAMSV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 VTMPKGRPEVDSLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFAR Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 RRFWLSGDAVGSANIASLGLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 QPWLADHAVAGTVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAG Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 GTVQLQVVVADAAGQPGSRSVAVYSRVAQSEWTLHAEGVLSEAAPAPAAE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 LSVWPPADAEAVDVAGGYDDLAGRGYGYGPAFRGLRAVWRRGAETFAEVE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 LPEQAGVSTGRFGIHPVLLDAALHALGVADKRLETVLPFSWQGVSLHAAG Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 ASRVRVRLAPAGAGAVSVELADASGVPVLSVRELVTRAVSAEQLAAAVAV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 RSGSGELLDVAWSVIEPRNSLPDNPISEGVTVWEPAAVDGAGPAAVHAAT Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 HQALGVLQSRLAGEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQ Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 AEHPGRVVLVDTDGSLDLATVIGCGEPQLVVRDGVAYRARLRPAGRRALL Mvan_5758|M.vanbaalenii_PYR-1 ---------------MRAAVLTAYNSP----------------------- MSMEG_5164|M.smegmatis_MC2_155 ---------MPTMTAIGSFAALPVDDP----------------------- MMAR_2950|M.marinum_M ------------MKAMAQRTWNPAEP------------------------ MUL_2209|M.ulcerans_Agy99 ------------MKAMAQRTWNPAEP------------------------ Mb3806|M.bovis_AF2122/97 ------------MTIMRAVVAESSD------------------------- Rv3777|M.tuberculosis_H37Rv ------------MTIMRAVVAESSD------------------------- MLBr_00118|M.leprae_Br4923 ---------------MHAIVAESAN------------------------- TH_1665|M.thermoresistible__bu ---------------MRAISVQTSG------------------------- MAB_0207c|M.abscessus_ATCC_199 ---------------MHAITVDNPGGP----------------------- Mflv_2124|M.gilvum_PYR-GCK -----------MSDRMKAVVLARFGGA----------------------- : MAV_3108|M.avium_104 ELPGPPAVWRLAAGDAGTLEDLAVQEHPAAELAPGQVRVRVAAAGVNFRD Mvan_5758|M.vanbaalenii_PYR-1 ---------------------LLVDELPDPEPGPGEVLVRVMASGVNPLD MSMEG_5164|M.smegmatis_MC2_155 -------------------DSLQDITIEVPELRPHDVLVRVEAVSVNPVD MMAR_2950|M.marinum_M ---------------------LELIELPTPEPKAGEVRVQVQAIGVNPVD MUL_2209|M.ulcerans_Agy99 ---------------------LEFIELPTPEPQAGEVRVQVQAIGVNPVD Mb3806|M.bovis_AF2122/97 --------------------RLVWQEVPDVSAGPGEVLIKVAASGVNRAD Rv3777|M.tuberculosis_H37Rv --------------------RLVWQEVPDVSAGPGEVLIKVAASGVNRAD MLBr_00118|M.leprae_Br4923 --------------------QMVWREVPDVTAGPGEVLIEVAASGVNRAD TH_1665|M.thermoresistible__bu --------------------QLSWVEVPDIEPGESEVLIAVHTAGINRAD MAB_0207c|M.abscessus_ATCC_199 -------------------EALRWTEVPDPVPGPGEILIDVTAAAANRAD Mflv_2124|M.gilvum_PYR-GCK -------------------DAFELRDVAVPHVGPRQVRVRVHATAVNPLD : :: : * : . * * MAV_3108|M.avium_104 VLVALG----------MYPGAAQLGAEGAGVVTEVGAGVTDVAVGDAVMG Mvan_5758|M.vanbaalenii_PYR-1 IKIRRGE-----APHAQLPPPAVLGIDMAGVVEAVGPRVDRFTVGDEVFG MSMEG_5164|M.smegmatis_MC2_155 IKRRRS--------LSPSAEPTILGFDAAGVVEAVGSEVTTLSVGDEVWY MMAR_2950|M.marinum_M WKMRSSGPLRLAARLIGPKPPVVVGVDFAGVVEAVGPGVTRAAPGDRVVG MUL_2209|M.ulcerans_Agy99 WKMRSSGPLRLAARLIGPKPPVVVGVDFAGVVEAVGPGVTRAAPGDRVVG Mb3806|M.bovis_AF2122/97 VLQAAGK------YPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVC- Rv3777|M.tuberculosis_H37Rv VLQAAGK------YPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVC- MLBr_00118|M.leprae_Br4923 VLQVAGK------YPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVC- TH_1665|M.thermoresistible__bu LLQAAGK------YPPPPGASEILGLEVSGTVAAVGAGVSGWTVGQPVC- MAB_0207c|M.abscessus_ATCC_199 LLQRRGL------YSPPPGASSILGLECSGTVAALGADVAHWSVGQPVC- Mflv_2124|M.gilvum_PYR-GCK YQIRRGD------YTDLVPLPAIIGHDISGVIEEVGSHVTEFRAGDAVYY . . :* : :* : :.. * *: * MAV_3108|M.avium_104 IFGLVG-------SEAAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYYGLS Mvan_5758|M.vanbaalenii_PYR-1 MTGGVGGLQGSLAELAAVDARLIAHKPRTLSMAQAAALPLGFITSWEGLV MSMEG_5164|M.smegmatis_MC2_155 AGDVSR--PGTNAQLHAVDERIVARKPRSLSFRDAAALPLTTITAWETLF MMAR_2950|M.marinum_M GTNFSRGQRGSYADTVLVREDQLCRVPDTVDIAVAAALPVGGVTAWMAVV MUL_2209|M.ulcerans_Agy99 GTNFSRGQRGSYADTVLVREDQLCRVPDTVDIAVAAALPVGGVTAWMAVV Mb3806|M.bovis_AF2122/97 --ALLAG--GGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLV Rv3777|M.tuberculosis_H37Rv --ALLAG--GGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLV MLBr_00118|M.leprae_Br4923 --ALLAG--GGYAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLV TH_1665|M.thermoresistible__bu --ALLAG--GGYAEYVAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLV MAB_0207c|M.abscessus_ATCC_199 --ALLSG--GGYAEKVVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMM Mflv_2124|M.gilvum_PYR-GCK TPKIFGGP-GSYAEQHVADVDLVGRKPDNLDHLEAASLTLVGGTVWESLV . . : * . :*.:. * : : MAV_3108|M.avium_104 VLAGLRAGQR----VLVHAATGGVGMAAVQLARHWGAEVFATASRG-KWD Mvan_5758|M.vanbaalenii_PYR-1 DRAGVGTGQQ----VLIHGGAGGVGFLAVQLALARGAQVYATGSTS-SQA MSMEG_5164|M.smegmatis_MC2_155 ERFNLTADSRGD--LLVLGAAGGVGSVMIQLAKKLTGVRVIATASR-DES MMAR_2950|M.marinum_M ELGRIRQVPPADRRVLVLGASGGVGQLAVQIAKLQEAFVVGVCSTK-NVE MUL_2209|M.ulcerans_Agy99 ELGRIRQVPSADRRVLVLGASGGVGQLAVQIAKLQEAFVVGVCSTE-NVE Mb3806|M.bovis_AF2122/97 MTAHLRPGQL----VLIHGGASGIGSHAIQVARALAARVAITAGSPEKLE Rv3777|M.tuberculosis_H37Rv MTAHLRPGQL----VLIHGGASGIGSHAIQVVRALAARVAITAGSPEKLE MLBr_00118|M.leprae_Br4923 MAAHLSAGQL----LLLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLE TH_1665|M.thermoresistible__bu MTAGLSAGEW----VLIHGGASGVGSHAVQVARALDARVAVTAGTRHKLE MAB_0207c|M.abscessus_ATCC_199 MTTKMSAGQS----ILIHGGASGIGTHTIQVAKALGLRVAVTAGTPEKLD Mflv_2124|M.gilvum_PYR-GCK TRAQLTVGET----ILIHGGAGGVGTIAIQVAKAMGARVITTAKAG-DHA : :*: ..:.*:* :*:. . . MAV_3108|M.avium_104 TLRAMGFDDAHIADSRTLDFEQKFGAAPGGMDVVLNSLAGEFNDASLRLL Mvan_5758|M.vanbaalenii_PYR-1 VIRAAGAVPIDYTATTVDEYVAAHTGGEG-FDVVADNVGGATLDAS---- MSMEG_5164|M.smegmatis_MC2_155 RQWARDLGADEVIDHHDLRTQALDVAPDG-VDYLFTPFSAGNVDVF---- MMAR_2950|M.marinum_M MVKDLGADLVLDYNQGDALAQAKPHAPFHVVIDCVGSYSGAGCR------ MUL_2209|M.ulcerans_Agy99 MVKDLGADLVLDYNQGDALAQAKPHAPFHVVIDCVGSYSGAGCR------ Mb3806|M.bovis_AF2122/97 LCRDLGAQITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRN---- Rv3777|M.tuberculosis_H37Rv LCRDLGAQITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRN---- MLBr_00118|M.leprae_Br4923 FCRALGAQITINYRDEDFVARLQQQN--GGADVILDIMGAAYLDRN---- TH_1665|M.thermoresistible__bu LCRELGAEVTICYREEDFVERVRAETDGAGADVVLDIMGAAYLGRN---- MAB_0207c|M.abscessus_ATCC_199 ACRDLGADLAINYRDTDFVQAVHSFTDGSGVDRILDIMGAKYLSRN---- Mflv_2124|M.gilvum_PYR-GCK FVNSLGADVAIDHTSTDYVDAVAEATRGRGVDVVFDTIGGDTLTRS---- . .. MAV_3108|M.avium_104 GPGGRFIEMGKTDLRDPDVVARAHPGVRYRAFDLMEAGPDRIAAMLAEVM Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 ELFAAGALTPLPVKAFDARCAADAYRFVSAARHIGKVVLTMPDGPAGLSG Mvan_5758|M.vanbaalenii_PYR-1 --------------------------FTAVKRYTGHVVSALGWGTHSLAP MSMEG_5164|M.smegmatis_MC2_155 ---------------------------ADIVRPFGHITAIDEPEGLDLVG MMAR_2950|M.marinum_M ----------------------------ALLSSRGRHIMVAGDEPSSALQ MUL_2209|M.ulcerans_Agy99 ----------------------------ALLSSRGRHIMVAGDEPSSAVQ Mb3806|M.bovis_AF2122/97 ---------------------------IDALATDGQLIVIGMQGGVKAEL Rv3777|M.tuberculosis_H37Rv ---------------------------IDALATDGQLIVIGMQGGVKAEL MLBr_00118|M.leprae_Br4923 ---------------------------IDALAIDGQLIVIGLQGGVKGEL TH_1665|M.thermoresistible__bu ---------------------------VDALATDGRLVVIGMQGGRRAEL MAB_0207c|M.abscessus_ATCC_199 ---------------------------VDALGNDGHLVIIGMQGGVTAEL Mflv_2124|M.gilvum_PYR-GCK ---------------------------PLSLADSGRVVSIVDIARPQNLI *: MAV_3108|M.avium_104 GTALITGATGMAGAALARHLVARHRVPHLMLVGRRGEAAPGMAELAAELR Mvan_5758|M.vanbaalenii_PYR-1 --------LSFRGAAYSGVFTLMP-----LLTGRGRDHHGEIVAEAAALA MSMEG_5164|M.smegmatis_MC2_155 --------LKTKSIAWHWELMFTR-----PLTGYDIAAQQRLLADAADLV MMAR_2950|M.marinum_M ----------VVVPPFKSKAILGR-------------PNGARLEPLVDAV MUL_2209|M.ulcerans_Agy99 ----------VVVPPFKSKAILGR-------------PNGARLEPLVDAV Mb3806|M.bovis_AF2122/97 N-------LGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMI Rv3777|M.tuberculosis_H37Rv N-------LGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMI MLBr_00118|M.leprae_Br4923 N-------LGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMI TH_1665|M.thermoresistible__bu D-------LGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMV MAB_0207c|M.abscessus_ATCC_199 N-------IAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLV Mflv_2124|M.gilvum_PYR-GCK E-------AWGRNAAYHFVFTRQNRGK---------------LDALTMLV MAV_3108|M.avium_104 GAGASVSVLSCDVG--DRDAVAAMLAQVPAR---YPLRSVFHAAGVLDDA Mvan_5758|M.vanbaalenii_PYR-1 DSGRLAPRLHPTTF--PLDAVNDAHTAVESG---SATGKVVVEPNV---- MSMEG_5164|M.smegmatis_MC2_155 DRGELRTTLTTAIDGFTAANLREAHRMVESG---RMVGKVVVSR------ MMAR_2950|M.marinum_M AAGKLRVSIAQKLP---LTSAEEAHRLSQTS---RMTGKLILEP------ MUL_2209|M.ulcerans_Agy99 AAGKLRVSIAQKLP---LTSAEEAHRLSQTS---RMTGKLILEP------ Mb3806|M.bovis_AF2122/97 AANRVRPVIGTRLP---IQQAAQAHELMLSG---KTFGKILLTV------ Rv3777|M.tuberculosis_H37Rv AANRVRPVIGTRLP---IQQAAQAHELMLSG---KTFGKILLTV------ MLBr_00118|M.leprae_Br4923 ADGSVRPIIGARMA---VQQAADAHQLLLSG---KVSGKIVLTVAGSGTE TH_1665|M.thermoresistible__bu ASDQVRPVVGAEFP---IQEAQAAHELLASG---DVYGKVLLCVED---- MAB_0207c|M.abscessus_ATCC_199 EAGKVRPVVGAEIP---LSQAAEAHRLLENG---AVVGKVLLTR------ Mflv_2124|M.gilvum_PYR-GCK ERGLVKPVLGATLP---LARMGEAHELLENRRSYALRGKVAIDVAGETVA . : .: MAV_3108|M.avium_104 VIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPG Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 TLLSRHH------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK LPPRIS-------------------------------------------- MAV_3108|M.avium_104 QGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEEPSAMTAHLEERDKAR Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 MSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLDRAALAQHRAALPPLL Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 SELAGRPARRMLEHTDMVSLTGLRARLAGMNPEQRQAELVELVCGNAAAV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 LGHSTADVDPGDAFSDLGFDSLTAVELRNRLKIATGLTLSPTVIFDHPTP Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 AALAEHLGGQLTSAGPTPAAPAETAAPPDRSSRIDEVVSELQTLLTQPGL Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 SPGDRAQLVTRLQSLLSTPPQPSGHPEFPEDAFDDDIATATDSQLFAILD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2950|M.marinum_M -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MAB_0207c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3108|M.avium_104 DEAGP Mvan_5758|M.vanbaalenii_PYR-1 ----- MSMEG_5164|M.smegmatis_MC2_155 ----- MMAR_2950|M.marinum_M ----- MUL_2209|M.ulcerans_Agy99 ----- Mb3806|M.bovis_AF2122/97 ----- Rv3777|M.tuberculosis_H37Rv ----- MLBr_00118|M.leprae_Br4923 ----- TH_1665|M.thermoresistible__bu ----- MAB_0207c|M.abscessus_ATCC_199 ----- Mflv_2124|M.gilvum_PYR-GCK -----