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M. bovis AF2122 / 97 Mb3806 (-)

annotation: putative oxidoreductase
coordinates: 4158989 - 4159975
length: 328

VTIMRAVVAESSDRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQAAGKYPPPPGVSDIIGLEVSGIVA
AVGPGVTEWSAGQEVCALLAGGGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPG
QLVLIHGGASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFVARLKQETDGSGAD
IILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQ
AVAASVWPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3806--100% (328)putative oxidoreductase
M. bovis AF2122 / 97Mb3855cpks26e-3831.60% (307) polyketide synthase PKS2
M. bovis AF2122 / 97Mb1213pks31e-3731.27% (307) polyketide beta-ketoacyl synthase PKS3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1189-1e-12368.32% (322) alcohol dehydrogenase
M. tuberculosis H37RvRv3777-0.099.70% (328) oxidoreductase
M. leprae Br4923MLBr_00118-1e-14376.31% (325) putative oxidireductase
M. abscessus ATCC 19977MAB_0207c-1e-11461.90% (315) quinone oxidoreductase
M. marinum MMMAR_5332-1e-15982.93% (328) oxidoreductase
M. avium 104MAV_0242-1e-14577.74% (328) quinone oxidoreductase
M. smegmatis MC2 155MSMEG_6362-1e-12768.62% (325) quinone oxidoreductase
M. thermoresistible (build 8)TH_1665-1e-13168.92% (325) PROBABLE OXIDOREDUCTASE
M. ulcerans Agy99MUL_0096-1e-15882.62% (328) oxidoreductase
M. vanbaalenii PYR-1Mvan_5615-1e-12065.64% (326) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3806|M.bovis_AF2122/97            MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
Rv3777|M.tuberculosis_H37Rv         MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
MMAR_5332|M.marinum_M               MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MUL_0096|M.ulcerans_Agy99           MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MLBr_00118|M.leprae_Br4923          ---MHAIVAESANQ---MVWREVPDVTAGPGEVLIEVAASGVNRADVLQV
MAV_0242|M.avium_104                MATMRAIVAESADQ---LSWQEVADVSAGPGEVVVKVAAAGVNRADVLQA
MSMEG_6362|M.smegmatis_MC2_155      ---MHAIVASVNGG---LNWENVASIAPANGEVLIKVHTAGINRADLLQA
Mflv_1189|M.gilvum_PYR-GCK          -------MAETPDQ---LNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA
Mvan_5615|M.vanbaalenii_PYR-1       --MHAIVAQPSSEG---LTWQSVPDIAPAPGEVLIRVAAAGVNRADLLQA
TH_1665|M.thermoresistible__bu      ---MRAISVQTSGQ---LSWVEVPDIEPGESEVLIAVHTAGINRADLLQA
MAB_0207c|M.abscessus_ATCC_199      ---MHAITVDNPGGPEALRWTEVPDPVPGPGEILIDVTAAAANRADLLQR
                                                     : * .*..  .. .*::: * ::. ****:** 

Mb3806|M.bovis_AF2122/97            AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
Rv3777|M.tuberculosis_H37Rv         AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
MMAR_5332|M.marinum_M               AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MUL_0096|M.ulcerans_Agy99           AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MLBr_00118|M.leprae_Br4923          AGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAEY
MAV_0242|M.avium_104                AGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGGYAEY
MSMEG_6362|M.smegmatis_MC2_155      AGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGGYAEY
Mflv_1189|M.gilvum_PYR-GCK          AGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGGYAEY
Mvan_5615|M.vanbaalenii_PYR-1       AGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGGYAEF
TH_1665|M.thermoresistible__bu      AGKYPPPPGASEILGLEVSGTVAAVGAGVSGWTVGQPVCALLAGGGYAEY
MAB_0207c|M.abscessus_ATCC_199      RGLYSPPPGASSILGLECSGTVAALGADVAHWSVGQPVCALLSGGGYAEK
                                     * *. ***.*  :*:* :* :  :. .*: *: ** *****:****** 

Mb3806|M.bovis_AF2122/97            VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
Rv3777|M.tuberculosis_H37Rv         VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
MMAR_5332|M.marinum_M               VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MUL_0096|M.ulcerans_Agy99           VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MLBr_00118|M.leprae_Br4923          VAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHG
MAV_0242|M.avium_104                VAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLLLVHG
MSMEG_6362|M.smegmatis_MC2_155      VAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLLLVHG
Mflv_1189|M.gilvum_PYR-GCK          VAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELLLIHG
Mvan_5615|M.vanbaalenii_PYR-1       VAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELLLVHG
TH_1665|M.thermoresistible__bu      VAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLVMTAGLSAGEWVLIHG
MAB_0207c|M.abscessus_ATCC_199      VVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMMMTTKMSAGQSILIHG
                                    *..** *::*:* .* :  :*.:**********::: : :   . :*:**

Mb3806|M.bovis_AF2122/97            GASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
Rv3777|M.tuberculosis_H37Rv         GASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
MMAR_5332|M.marinum_M               GASGIGSHAIQVCTALGARVAVTAGSSEKLQLCRDLGAQITINYRDEDFV
MUL_0096|M.ulcerans_Agy99           GACGIGSHAIQVCTALGARVAVTAGSSEKLQLSRDLGAQITINYRDEDFV
MLBr_00118|M.leprae_Br4923          GTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDFV
MAV_0242|M.avium_104                GASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRDEDFV
MSMEG_6362|M.smegmatis_MC2_155      GASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYREEDFV
Mflv_1189|M.gilvum_PYR-GCK          GASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHHEDFV
Mvan_5615|M.vanbaalenii_PYR-1       GASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHNEDYV
TH_1665|M.thermoresistible__bu      GASGVGSHAVQVARALDARVAVTAGTRHKLELCRELGAEVTICYREEDFV
MAB_0207c|M.abscessus_ATCC_199      GASGIGTHTIQVAKALGLRVAVTAGTPEKLDACRDLGADLAINYRDTDFV
                                    *:.*:*:* :**  *:  :**:***: .**  .  ***:::* *:. *:*

Mb3806|M.bovis_AF2122/97            ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
Rv3777|M.tuberculosis_H37Rv         ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
MMAR_5332|M.marinum_M               ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MUL_0096|M.ulcerans_Agy99           ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MLBr_00118|M.leprae_Br4923          ARLQQQN---GGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKGE
MAV_0242|M.avium_104                ARLADET---GGADVILDIMGAAYLDRNIDALATDGQLVIIGMQGGVKAE
MSMEG_6362|M.smegmatis_MC2_155      ERLRRET---DGADVILDIMGAAYLDRNVDALATGGRLVIIGMQGGVKAE
Mflv_1189|M.gilvum_PYR-GCK          EVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGGTKAE
Mvan_5615|M.vanbaalenii_PYR-1       GVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGGAKAE
TH_1665|M.thermoresistible__bu      ERVRAETDG-AGADVVLDIMGAAYLGRNVDALATDGRLVVIGMQGGRRAE
MAB_0207c|M.abscessus_ATCC_199      QAVHSFTDG-SGVDRILDIMGAKYLSRNVDALGNDGHLVIIGMQGGVTAE
                                      :        *.* :****** **.**:::*. .*:*::**:***  .*

Mb3806|M.bovis_AF2122/97            LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
Rv3777|M.tuberculosis_H37Rv         LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
MMAR_5332|M.marinum_M               LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MUL_0096|M.ulcerans_Agy99           LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MLBr_00118|M.leprae_Br4923          LNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVR
MAV_0242|M.avium_104                LNIGKLLAKRARVIGTTLRGRPVSGPNSKTEIVQAVTASVWPMIADGRVR
MSMEG_6362|M.smegmatis_MC2_155      LNIGKLLGKRAGVIATSLRPRPVDGPGGKGEIVRAVRENVWPMIADGRVK
Mflv_1189|M.gilvum_PYR-GCK          INLGKLLAKRGSVMATALRSRPVTGRGSKSVIVSEVIENVWPLVADGQVR
Mvan_5615|M.vanbaalenii_PYR-1       LNIGKLLTKRGSVIATALRSRPVHGRGGKADIVARVGAELWPLVADGQVR
TH_1665|M.thermoresistible__bu      LDLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQVR
MAB_0207c|M.abscessus_ATCC_199      LNIAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLVEAGKVR
                                    :::.*:: **. : .::** **: *  .*  *.  *  .:**::  . *:

Mb3806|M.bovis_AF2122/97            PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
Rv3777|M.tuberculosis_H37Rv         PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
MMAR_5332|M.marinum_M               PIIGSRLPIGQAAQAHQLLLSGQSYGKTLLTVDG-----------
MUL_0096|M.ulcerans_Agy99           PIIGSRLPIGQAAQAHQLLLSGQSYGKILLTVDG-----------
MLBr_00118|M.leprae_Br4923          PIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
MAV_0242|M.avium_104                PIIGARLPIQQAGDAHRRLVASEVTGKIVLTV-------------
MSMEG_6362|M.smegmatis_MC2_155      PIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE-----------
Mflv_1189|M.gilvum_PYR-GCK          PVIGAEFPISEAQAAHELLASGDVSGKVILRVDV-----------
Mvan_5615|M.vanbaalenii_PYR-1       PVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV-----------
TH_1665|M.thermoresistible__bu      PVVGAEFPIQEAQAAHELLASGDVYGKVLLCVED-----------
MAB_0207c|M.abscessus_ATCC_199      PVVGAEIPLSQAAEAHRLLENGAVVGKVLLTR-------------
                                    *::*:.:.: :*  .*  :  .   ** :*