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VTIMRAVVAESSDRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQAAGKYPPPPGVSDIIGLEVSGIVA AVGPGVTEWSAGQEVCALLAGGGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPG QLVLIHGGASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFVARLKQETDGSGAD IILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQ AVAASVWPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3806 | - | - | 100% (328) | putative oxidoreductase |
M. bovis AF2122 / 97 | Mb3855c | pks2 | 6e-38 | 31.60% (307) | polyketide synthase PKS2 |
M. bovis AF2122 / 97 | Mb1213 | pks3 | 1e-37 | 31.27% (307) | polyketide beta-ketoacyl synthase PKS3 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1189 | - | 1e-123 | 68.32% (322) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv3777 | - | 0.0 | 99.70% (328) | oxidoreductase |
M. leprae Br4923 | MLBr_00118 | - | 1e-143 | 76.31% (325) | putative oxidireductase |
M. abscessus ATCC 19977 | MAB_0207c | - | 1e-114 | 61.90% (315) | quinone oxidoreductase |
M. marinum M | MMAR_5332 | - | 1e-159 | 82.93% (328) | oxidoreductase |
M. avium 104 | MAV_0242 | - | 1e-145 | 77.74% (328) | quinone oxidoreductase |
M. smegmatis MC2 155 | MSMEG_6362 | - | 1e-127 | 68.62% (325) | quinone oxidoreductase |
M. thermoresistible (build 8) | TH_1665 | - | 1e-131 | 68.92% (325) | PROBABLE OXIDOREDUCTASE |
M. ulcerans Agy99 | MUL_0096 | - | 1e-158 | 82.62% (328) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_5615 | - | 1e-120 | 65.64% (326) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3806|M.bovis_AF2122/97 MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA Rv3777|M.tuberculosis_H37Rv MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA MMAR_5332|M.marinum_M MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA MUL_0096|M.ulcerans_Agy99 MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA MLBr_00118|M.leprae_Br4923 ---MHAIVAESANQ---MVWREVPDVTAGPGEVLIEVAASGVNRADVLQV MAV_0242|M.avium_104 MATMRAIVAESADQ---LSWQEVADVSAGPGEVVVKVAAAGVNRADVLQA MSMEG_6362|M.smegmatis_MC2_155 ---MHAIVASVNGG---LNWENVASIAPANGEVLIKVHTAGINRADLLQA Mflv_1189|M.gilvum_PYR-GCK -------MAETPDQ---LNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA Mvan_5615|M.vanbaalenii_PYR-1 --MHAIVAQPSSEG---LTWQSVPDIAPAPGEVLIRVAAAGVNRADLLQA TH_1665|M.thermoresistible__bu ---MRAISVQTSGQ---LSWVEVPDIEPGESEVLIAVHTAGINRADLLQA MAB_0207c|M.abscessus_ATCC_199 ---MHAITVDNPGGPEALRWTEVPDPVPGPGEILIDVTAAAANRADLLQR : * .*.. .. .*::: * ::. ****:** Mb3806|M.bovis_AF2122/97 AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY Rv3777|M.tuberculosis_H37Rv AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY MMAR_5332|M.marinum_M AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY MUL_0096|M.ulcerans_Agy99 AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY MLBr_00118|M.leprae_Br4923 AGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAEY MAV_0242|M.avium_104 AGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGGYAEY MSMEG_6362|M.smegmatis_MC2_155 AGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGGYAEY Mflv_1189|M.gilvum_PYR-GCK AGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGGYAEY Mvan_5615|M.vanbaalenii_PYR-1 AGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGGYAEF TH_1665|M.thermoresistible__bu AGKYPPPPGASEILGLEVSGTVAAVGAGVSGWTVGQPVCALLAGGGYAEY MAB_0207c|M.abscessus_ATCC_199 RGLYSPPPGASSILGLECSGTVAALGADVAHWSVGQPVCALLSGGGYAEK * *. ***.* :*:* :* : :. .*: *: ** *****:****** Mb3806|M.bovis_AF2122/97 VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG Rv3777|M.tuberculosis_H37Rv VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG MMAR_5332|M.marinum_M VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG MUL_0096|M.ulcerans_Agy99 VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG MLBr_00118|M.leprae_Br4923 VAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHG MAV_0242|M.avium_104 VAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLLLVHG MSMEG_6362|M.smegmatis_MC2_155 VAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLLLVHG Mflv_1189|M.gilvum_PYR-GCK VAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELLLIHG Mvan_5615|M.vanbaalenii_PYR-1 VAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELLLVHG TH_1665|M.thermoresistible__bu VAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLVMTAGLSAGEWVLIHG MAB_0207c|M.abscessus_ATCC_199 VVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMMMTTKMSAGQSILIHG *..** *::*:* .* : :*.:**********::: : : . :*:** Mb3806|M.bovis_AF2122/97 GASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV Rv3777|M.tuberculosis_H37Rv GASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV MMAR_5332|M.marinum_M GASGIGSHAIQVCTALGARVAVTAGSSEKLQLCRDLGAQITINYRDEDFV MUL_0096|M.ulcerans_Agy99 GACGIGSHAIQVCTALGARVAVTAGSSEKLQLSRDLGAQITINYRDEDFV MLBr_00118|M.leprae_Br4923 GTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDFV MAV_0242|M.avium_104 GASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRDEDFV MSMEG_6362|M.smegmatis_MC2_155 GASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYREEDFV Mflv_1189|M.gilvum_PYR-GCK GASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHHEDFV Mvan_5615|M.vanbaalenii_PYR-1 GASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHNEDYV TH_1665|M.thermoresistible__bu GASGVGSHAVQVARALDARVAVTAGTRHKLELCRELGAEVTICYREEDFV MAB_0207c|M.abscessus_ATCC_199 GASGIGTHTIQVAKALGLRVAVTAGTPEKLDACRDLGADLAINYRDTDFV *:.*:*:* :** *: :**:***: .** . ***:::* *:. *:* Mb3806|M.bovis_AF2122/97 ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE Rv3777|M.tuberculosis_H37Rv ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE MMAR_5332|M.marinum_M ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE MUL_0096|M.ulcerans_Agy99 ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE MLBr_00118|M.leprae_Br4923 ARLQQQN---GGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKGE MAV_0242|M.avium_104 ARLADET---GGADVILDIMGAAYLDRNIDALATDGQLVIIGMQGGVKAE MSMEG_6362|M.smegmatis_MC2_155 ERLRRET---DGADVILDIMGAAYLDRNVDALATGGRLVIIGMQGGVKAE Mflv_1189|M.gilvum_PYR-GCK EVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGGTKAE Mvan_5615|M.vanbaalenii_PYR-1 GVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGGAKAE TH_1665|M.thermoresistible__bu ERVRAETDG-AGADVVLDIMGAAYLGRNVDALATDGRLVVIGMQGGRRAE MAB_0207c|M.abscessus_ATCC_199 QAVHSFTDG-SGVDRILDIMGAKYLSRNVDALGNDGHLVIIGMQGGVTAE : *.* :****** **.**:::*. .*:*::**:*** .* Mb3806|M.bovis_AF2122/97 LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR Rv3777|M.tuberculosis_H37Rv LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR MMAR_5332|M.marinum_M LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR MUL_0096|M.ulcerans_Agy99 LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR MLBr_00118|M.leprae_Br4923 LNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVR MAV_0242|M.avium_104 LNIGKLLAKRARVIGTTLRGRPVSGPNSKTEIVQAVTASVWPMIADGRVR MSMEG_6362|M.smegmatis_MC2_155 LNIGKLLGKRAGVIATSLRPRPVDGPGGKGEIVRAVRENVWPMIADGRVK Mflv_1189|M.gilvum_PYR-GCK INLGKLLAKRGSVMATALRSRPVTGRGSKSVIVSEVIENVWPLVADGQVR Mvan_5615|M.vanbaalenii_PYR-1 LNIGKLLTKRGSVIATALRSRPVHGRGGKADIVARVGAELWPLVADGQVR TH_1665|M.thermoresistible__bu LDLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQVR MAB_0207c|M.abscessus_ATCC_199 LNIAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLVEAGKVR :::.*:: **. : .::** **: * .* *. * .:**:: . *: Mb3806|M.bovis_AF2122/97 PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV------------- Rv3777|M.tuberculosis_H37Rv PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV------------- MMAR_5332|M.marinum_M PIIGSRLPIGQAAQAHQLLLSGQSYGKTLLTVDG----------- MUL_0096|M.ulcerans_Agy99 PIIGSRLPIGQAAQAHQLLLSGQSYGKILLTVDG----------- MLBr_00118|M.leprae_Br4923 PIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH MAV_0242|M.avium_104 PIIGARLPIQQAGDAHRRLVASEVTGKIVLTV------------- MSMEG_6362|M.smegmatis_MC2_155 PIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE----------- Mflv_1189|M.gilvum_PYR-GCK PVIGAEFPISEAQAAHELLASGDVSGKVILRVDV----------- Mvan_5615|M.vanbaalenii_PYR-1 PVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV----------- TH_1665|M.thermoresistible__bu PVVGAEFPIQEAQAAHELLASGDVYGKVLLCVED----------- MAB_0207c|M.abscessus_ATCC_199 PVVGAEIPLSQAAEAHRLLENGAVVGKVLLTR------------- *::*:.:.: :* .* : . ** :*