For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1665 ()

annotation: PROBABLE OXIDOREDUCTASE
coordinates: 3233785 - 3234768
length: 328

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1665-100% (328)PROBABLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_4621-2e-3730.98% (326) PUTATIVE mycocerosic acid synthase
M. thermoresistible (build 8)TH_2952-2e-3532.82% (323) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3806-1e-13168.92% (325) putative oxidoreductase
M. gilvum PYR-GCKMflv_1189-1e-13071.96% (321) alcohol dehydrogenase
M. tuberculosis H37RvRv3777-1e-13168.62% (325) oxidoreductase
M. leprae Br4923MLBr_00118-1e-11861.85% (325) putative oxidireductase
M. abscessus ATCC 19977MAB_0207c-1e-11361.66% (326) quinone oxidoreductase
M. marinum MMMAR_5332-1e-12566.26% (326) oxidoreductase
M. avium 104MAV_0242-1e-12365.85% (325) quinone oxidoreductase
M. smegmatis MC2 155MSMEG_6362-1e-13370.95% (327) quinone oxidoreductase
M. ulcerans Agy99MUL_0096-1e-12465.64% (326) oxidoreductase
M. vanbaalenii PYR-1Mvan_5615-1e-12668.81% (327) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1189|M.gilvum_PYR-GCK          -------MAETPDQ---LNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA
Mvan_5615|M.vanbaalenii_PYR-1       --MHAIVAQPSSEG---LTWQSVPDIAPAPGEVLIRVAAAGVNRADLLQA
TH_1665|M.thermoresistible__bu      ---MRAISVQTSGQ---LSWVEVPDIEPGESEVLIAVHTAGINRADLLQA
Mb3806|M.bovis_AF2122/97            MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
Rv3777|M.tuberculosis_H37Rv         MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
MMAR_5332|M.marinum_M               MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MUL_0096|M.ulcerans_Agy99           MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MLBr_00118|M.leprae_Br4923          ---MHAIVAESANQ---MVWREVPDVTAGPGEVLIEVAASGVNRADVLQV
MAV_0242|M.avium_104                MATMRAIVAESADQ---LSWQEVADVSAGPGEVVVKVAAAGVNRADVLQA
MSMEG_6362|M.smegmatis_MC2_155      ---MHAIVASVNGG---LNWENVASIAPANGEVLIKVHTAGINRADLLQA
MAB_0207c|M.abscessus_ATCC_199      ---MHAITVDNPGGPEALRWTEVPDPVPGPGEILIDVTAAAANRADLLQR
                                                     : * .*..  .. .*::: * ::. ****:** 

Mflv_1189|M.gilvum_PYR-GCK          AGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGGYAEY
Mvan_5615|M.vanbaalenii_PYR-1       AGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGGYAEF
TH_1665|M.thermoresistible__bu      AGKYPPPPGASEILGLEVSGTVAAVGAGVSGWTVGQPVCALLAGGGYAEY
Mb3806|M.bovis_AF2122/97            AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
Rv3777|M.tuberculosis_H37Rv         AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
MMAR_5332|M.marinum_M               AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MUL_0096|M.ulcerans_Agy99           AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MLBr_00118|M.leprae_Br4923          AGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAEY
MAV_0242|M.avium_104                AGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGGYAEY
MSMEG_6362|M.smegmatis_MC2_155      AGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGGYAEY
MAB_0207c|M.abscessus_ATCC_199      RGLYSPPPGASSILGLECSGTVAALGADVAHWSVGQPVCALLSGGGYAEK
                                     * *. ***.*  :*:* :* :  :. .*: *: ** *****:****** 

Mflv_1189|M.gilvum_PYR-GCK          VAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELLLIHG
Mvan_5615|M.vanbaalenii_PYR-1       VAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELLLVHG
TH_1665|M.thermoresistible__bu      VAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLVMTAGLSAGEWVLIHG
Mb3806|M.bovis_AF2122/97            VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
Rv3777|M.tuberculosis_H37Rv         VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
MMAR_5332|M.marinum_M               VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MUL_0096|M.ulcerans_Agy99           VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MLBr_00118|M.leprae_Br4923          VAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHG
MAV_0242|M.avium_104                VAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLLLVHG
MSMEG_6362|M.smegmatis_MC2_155      VAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLLLVHG
MAB_0207c|M.abscessus_ATCC_199      VVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMMMTTKMSAGQSILIHG
                                    *..** *::*:* .* :  :*.:**********::: : :   . :*:**

Mflv_1189|M.gilvum_PYR-GCK          GASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHHEDFV
Mvan_5615|M.vanbaalenii_PYR-1       GASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHNEDYV
TH_1665|M.thermoresistible__bu      GASGVGSHAVQVARALDARVAVTAGTRHKLELCRELGAEVTICYREEDFV
Mb3806|M.bovis_AF2122/97            GASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
Rv3777|M.tuberculosis_H37Rv         GASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
MMAR_5332|M.marinum_M               GASGIGSHAIQVCTALGARVAVTAGSSEKLQLCRDLGAQITINYRDEDFV
MUL_0096|M.ulcerans_Agy99           GACGIGSHAIQVCTALGARVAVTAGSSEKLQLSRDLGAQITINYRDEDFV
MLBr_00118|M.leprae_Br4923          GTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDFV
MAV_0242|M.avium_104                GASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRDEDFV
MSMEG_6362|M.smegmatis_MC2_155      GASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYREEDFV
MAB_0207c|M.abscessus_ATCC_199      GASGIGTHTIQVAKALGLRVAVTAGTPEKLDACRDLGADLAINYRDTDFV
                                    *:.*:*:* :**  *:  :**:***: .**  .  ***:::* *:. *:*

Mflv_1189|M.gilvum_PYR-GCK          EVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGGTKAE
Mvan_5615|M.vanbaalenii_PYR-1       GVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGGAKAE
TH_1665|M.thermoresistible__bu      ERVRAETDG-AGADVVLDIMGAAYLGRNVDALATDGRLVVIGMQGGRRAE
Mb3806|M.bovis_AF2122/97            ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
Rv3777|M.tuberculosis_H37Rv         ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
MMAR_5332|M.marinum_M               ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MUL_0096|M.ulcerans_Agy99           ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MLBr_00118|M.leprae_Br4923          ARLQQQN---GGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKGE
MAV_0242|M.avium_104                ARLADET---GGADVILDIMGAAYLDRNIDALATDGQLVIIGMQGGVKAE
MSMEG_6362|M.smegmatis_MC2_155      ERLRRET---DGADVILDIMGAAYLDRNVDALATGGRLVIIGMQGGVKAE
MAB_0207c|M.abscessus_ATCC_199      QAVHSFTDG-SGVDRILDIMGAKYLSRNVDALGNDGHLVIIGMQGGVTAE
                                      :        *.* :****** **.**:::*. .*:*::**:***  .*

Mflv_1189|M.gilvum_PYR-GCK          INLGKLLAKRGSVMATALRSRPVTGRGSKSVIVSEVIENVWPLVADGQVR
Mvan_5615|M.vanbaalenii_PYR-1       LNIGKLLTKRGSVIATALRSRPVHGRGGKADIVARVGAELWPLVADGQVR
TH_1665|M.thermoresistible__bu      LDLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQVR
Mb3806|M.bovis_AF2122/97            LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
Rv3777|M.tuberculosis_H37Rv         LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
MMAR_5332|M.marinum_M               LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MUL_0096|M.ulcerans_Agy99           LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MLBr_00118|M.leprae_Br4923          LNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVR
MAV_0242|M.avium_104                LNIGKLLAKRARVIGTTLRGRPVSGPNSKTEIVQAVTASVWPMIADGRVR
MSMEG_6362|M.smegmatis_MC2_155      LNIGKLLGKRAGVIATSLRPRPVDGPGGKGEIVRAVRENVWPMIADGRVK
MAB_0207c|M.abscessus_ATCC_199      LNIAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLVEAGKVR
                                    :::.*:: **. : .::** **: *  .*  *.  *  .:**::  . *:

Mflv_1189|M.gilvum_PYR-GCK          PVIGAEFPISEAQAAHELLASGDVSGKVILRVDV-----------
Mvan_5615|M.vanbaalenii_PYR-1       PVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV-----------
TH_1665|M.thermoresistible__bu      PVVGAEFPIQEAQAAHELLASGDVYGKVLLCVED-----------
Mb3806|M.bovis_AF2122/97            PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
Rv3777|M.tuberculosis_H37Rv         PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
MMAR_5332|M.marinum_M               PIIGSRLPIGQAAQAHQLLLSGQSYGKTLLTVDG-----------
MUL_0096|M.ulcerans_Agy99           PIIGSRLPIGQAAQAHQLLLSGQSYGKILLTVDG-----------
MLBr_00118|M.leprae_Br4923          PIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
MAV_0242|M.avium_104                PIIGARLPIQQAGDAHRRLVASEVTGKIVLTV-------------
MSMEG_6362|M.smegmatis_MC2_155      PIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE-----------
MAB_0207c|M.abscessus_ATCC_199      PVVGAEIPLSQAAEAHRLLENGAVVGKVLLTR-------------
                                    *::*:.:.: :*  .*  :  .   ** :*