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VRAAVLTAYNSPLLVDELPDPEPGPGEVLVRVMASGVNPLDIKIRRGEAPHAQLPPPAVLGIDMAGVVEA VGPRVDRFTVGDEVFGMTGGVGGLQGSLAELAAVDARLIAHKPRTLSMAQAAALPLGFITSWEGLVDRAG VGTGQQVLIHGGAGGVGFLAVQLALARGAQVYATGSTSSQAVIRAAGAVPIDYTATTVDEYVAAHTGGEG FDVVADNVGGATLDASFTAVKRYTGHVVSALGWGTHSLAPLSFRGAAYSGVFTLMPLLTGRGRDHHGEIV AEAAALADSGRLAPRLHPTTFPLDAVNDAHTAVESGSATGKVVVEPNV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5758 | - | - | 100% (328) | alcohol dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_5615 | - | 7e-30 | 30.21% (341) | alcohol dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_4202 | - | 8e-29 | 30.79% (328) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3806 | - | 3e-34 | 32.44% (336) | putative oxidoreductase |
M. gilvum PYR-GCK | Mflv_2124 | - | 2e-44 | 40.00% (310) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv3777 | - | 1e-33 | 32.14% (336) | oxidoreductase |
M. leprae Br4923 | MLBr_00118 | - | 6e-31 | 31.83% (333) | putative oxidireductase |
M. abscessus ATCC 19977 | MAB_1486c | - | 3e-31 | 33.23% (331) | putative oxidoreductase |
M. marinum M | MMAR_3099 | - | 1e-33 | 42.93% (205) | polyketide synthase and peptide synthetase |
M. avium 104 | MAV_3108 | - | 9e-34 | 37.14% (315) | erythronolide synthase, modules 3 and 4 |
M. smegmatis MC2 155 | MSMEG_5164 | - | 9e-36 | 37.58% (314) | zinc-binding alcohol dehydrogenase family protein |
M. thermoresistible (build 8) | TH_1665 | - | 3e-33 | 34.59% (318) | PROBABLE OXIDOREDUCTASE |
M. ulcerans Agy99 | MUL_2209 | - | 1e-32 | 34.15% (328) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3099|M.marinum_M MSLILDRVRELGTQIPDAAALSFVNDRGLVTESMSRVDVVTEMNKVAQFV MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M RQDCGLAPGDRAVLVYPPGLDFVCGLLGCMAAGVIAVPVFPPDPINPQKS MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M GAAFRRVALDCGATAVLTSHHYADARQLEVAAPVGTAFDEDWPNALPWHV MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M TSRGASGRGKSAPRAVSEAISEWAPSPQTPALLQYTSGSTSDPKGVVITH MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M GNVVHQAEFNRRFIGLGPGHRAVFWVPPYHDFGLISGILSALAGNFDLTM MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M MSPMSFIQRPALWFEVMDRVRATVTVAPNFGFELAMRKTTAEQRAGWDLS MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M PLQVIVSAAEPVREDTTRRFFEAFAASGIRREAFCPCYGLAEHTVGITVS MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M GRSSLRVDRSQLEARQLAVPSDAPDAQVLMGCGQPTDDVDVRIVDPELCV MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M PLGDGQVGEIWADSPSKAAGYWGLSAKSRATFQAALAGVEGGRGYLRTGD MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M LGFLHDGELYVCGRIKDLLILAGRNIYPQDIEDSLRDCHPAIRPGGFAAF MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AVVDGNSETLAVLVEVRTDGSPDLLAGVVAAIRAAVLKDHQLRCGVVVLG MAV_3108|M.avium_104 -------------------------------------------------- Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M PPGSVSKTTSGKVQRSRCRARFLDGTLQAQALLVDRRTDDEPVGAAPTTE MAV_3108|M.avium_104 ---------------------------------------------MPGTE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M QLLSVVCGQAAEVLGIGAASVDIDRSLGDQGLNSIGVTELASRLTQVLGQ MAV_3108|M.avium_104 QHLDYLKRLTADLR------------------------------------ Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M DVQPVDIFNHPTVGDLVQILSPGEKTRHQRGVRERLGHHAASGAGAVALP MAV_3108|M.avium_104 --------------------------RTRRRVAELEGR-----------L Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M ADPVAIVGIGCRFPGGVDSADSLWDMVVSARDVISDFPGDRGWDAGRLFD MAV_3108|M.avium_104 SEPVAVVGMACRYAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M PDPDALGKTYCAVGGFLEDAAGFDAGFFGIAPREALAMDPQQRVLLEVSW MAV_3108|M.avium_104 PDPDAKGKMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICW Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M EALEDAGIDPKALRGSATGVFVGTWAQPYGDGGSDSADGYAMTGTATSVA MAV_3108|M.avium_104 EALERAGIDPSALRGTATGVFAGVIHAGYGGEVKGELEGYGLTGSTLSVT Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M SGRVAYVLGLEGPAVSVDTACSSSLVAVHQAVQSLRLGECDLALAGGVTV MAV_3108|M.avium_104 SGRVSYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M MATPSVFVGFSRQRGLAPDGRCKAFAEAADGVGWGEGAGVLVLQRLSDAR MAV_3108|M.avium_104 MATPAAFVEFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADAR Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M RQGRVVLGVVRGSAVNQDGASHGLTAPNGPAQQRVIRAALAGAGLGPADV MAV_3108|M.avium_104 RLGHPVWAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M DVVEAHGTGTRLGDPIEAQALLAVYGQDREPGRPLWVGSIKSNMGHAQAA MAV_3108|M.avium_104 DVVEGHGTGTVLGDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTSAA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AGVAGVIKMVQAMRHGLLPETLHVDEPSGQVDWSAGAVEVLSRARSWLGV MAV_3108|M.avium_104 AGVAGVIKMVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWP-E Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M PGRPRRAGVSSFGISGTNAHVIVEQALPEVAESGGVSGVCGQGVGSVESV MAV_3108|M.avium_104 HGGPRRAGVSSFGISGTNAHVIVEQAP-AAAETEAAP---------ASST Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M VRASVVPWVLSAQSRQALVAQASRLLGRVGGDDGLDPVDVGLSLA-QRCV MAV_3108|M.avium_104 MPDAVVPWVVSARSAEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M FEHRAVVVGRDREALLAGLTGLARGGPGAGVVVGQAAAVGKTVLVFPGQG MAV_3108|M.avium_104 FEHRAVVVGRERGALATGLAGLASGRPGPATVVGRARSTGKTVLVFPGQG Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AQWTGMGRGLHGQFPAFARAFDAAVDELDQHLPMPLREVMWGTDKGLLDS MAV_3108|M.avium_104 SQTLGMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGADPELLQS Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M TEFAQPALFALEVGLWALLEHWGIRPDFVLGHSVGELSAAHVAGVLSLAD MAV_3108|M.avium_104 TEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLSLRD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AAMLVAARGRLMQGLPAGGVMVALGVGEQEVDPLLAESAHPVSIAAINAP MAV_3108|M.avium_104 AARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGG---GVSIAAVNGP Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M EQVVISGAQAAVMTIADQLAARGHRVQQLAVSHAFHSPLMEPIVEEFAEI MAV_3108|M.avium_104 DAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGFAAA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AGRVTVEAPRIGVISNLTGELAGPGYGSKAYWREHIRRPVRFSDSVACAR MAV_3108|M.avium_104 AAGIEPRPPRIPLVSNLTGQLAGPGYGTPQYWVDHVRRPVRFVDGVRLAE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AQGATHFVEAGPGAGLTAAIEQSLGSVAATVVAVLGKQRPEPDSLLDAAA MAV_3108|M.avium_104 SQGAGVFLEVGPGAALTSAVEQSLTSDRAMSVVTMPKGRPEVDSLLTAAA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M QLFASGARLDWPAVFLGWGGRRVSLPTYAFMRQRFWLTPHLAGSVGAAEL MAV_3108|M.avium_104 RLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLSGDAVGSANIASL Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M GSGNPRHPLLDAVVEHPDSGEVILAGRLSRRAQPWLADHVIGGLVLLPGT MAV_3108|M.avium_104 GLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAAQPWLADHAVAGTVLFPGA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M GFVELVIRAGDQLGCAAIDELTLTNPLIVPDGSEVQVQVVVG-AAERSGR MAV_3108|M.avium_104 GFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVADAAGQPGS Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M RTVSVYSRADHIGAAWVQHAEGALGVDPMPASGDFSVWPPSGAEAVRVSD MAV_3108|M.avium_104 RSVAVYSRVAQS--EWTLHAEGVLSEAAPAPAAELSVWPPADAEAVDVAG Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AYERLAQLGYRYGPAFRGIEAIWRRGTEVYAEVAIPADAELGINGYGIHP MAV_3108|M.avium_104 GYDDLAGRGYGYGPAFRGLRAVWRRGAETFAEVELPEQAGVSTGRFGIHP Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M VLLDAVLQAAAVAVDSGDTRLPYSWRGISLHAAAAKRIRARIAPVGEVGY MAV_3108|M.avium_104 VLLDAALHALGVADKRLETVLPFSWQGVSLHAAGASRVRVRLAPAGAGAV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M AVECADVAGLPVLTMGSLVTRPVSAEQLHAGAATAIGRPAQGLLELAWSP MAV_3108|M.avium_104 SVELADASGVPVLSVRELVTRAVSAEQLAAAVAVRSG--SGELLDVAWSV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M ISPAHGALDGGGHQTVLSWADFTAGAAAAADGVGGRAVAVVWESRTAETD MAV_3108|M.avium_104 IEPRNSLPDN-----------------PISEGVT------VWEPAAVDGA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M VVGSVYARIHAALSVLQHWLAQDQLASLVVVTHGAVGLPGEAITDLAGSA MAV_3108|M.avium_104 GPAAVHAATHQALGVLQSRLAGEAGGVLVVSTRGAVGLPGEDVADLAGAA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M VWGLARSAQAESPGRIVLVDIDTPNTPDLGVLLAGREPQLVVRGDSVFCA MAV_3108|M.avium_104 VWGLVRSAQAEHPGRVVLVDTDG--SLDLATVIGCGEPQLVVRDGVAYRA Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M RLRPV--EAPLEVPVGQSAWQLSTGGGGTLADIVVQPCPPAQAPLEPGQV MAV_3108|M.avium_104 RLRPAGRRALLELPGPPAVWRLAAGDAGTLEDLAVQEHP--AAELAPGQV Mvan_5758|M.vanbaalenii_PYR-1 ----------------MRAAVLTAYNSPLLVDELPDPEP------GPGEV Mflv_2124|M.gilvum_PYR-GCK ------------MSDRMKAVVLARFGGADAFELRDVAVP----HVGPRQV MAB_1486c|M.abscessus_ATCC_199 ---------------MTQAIVATSYGGADVLEFRDITTP----GPGPGQV Mb3806|M.bovis_AF2122/97 -------------MTIMRAVVAESSDRLVWQEVPDVSAG-------PGEV Rv3777|M.tuberculosis_H37Rv -------------MTIMRAVVAESSDRLVWQEVPDVSAG-------PGEV MLBr_00118|M.leprae_Br4923 ----------------MHAIVAESANQMVWREVPDVTAG-------PGEV TH_1665|M.thermoresistible__bu ----------------MRAISVQTSGQLSWVEVPDIEPG-------ESEV MUL_2209|M.ulcerans_Agy99 ----------------MKAMAQRTWNPAEPLEFIELPTP----EPQAGEV MSMEG_5164|M.smegmatis_MC2_155 ----------MPTMTAIGSFAALPVDDPDSLQDITIEVP----ELRPHDV . : :* MMAR_3099|M.marinum_M RVAVAAAGVNFRDVLMA-----LGMYPGAQP----VLGGEGSGVVLEVGP MAV_3108|M.avium_104 RVRVAAAGVNFRDVLVA-----LGMYPGAA-----QLGAEGAGVVTEVGA Mvan_5758|M.vanbaalenii_PYR-1 LVRVMASGVNPLDIKIR-----RGEAPHAQLPPPAVLGIDMAGVVEAVGP Mflv_2124|M.gilvum_PYR-GCK RVRVHATAVNPLDYQIR-----RGDY-TDLVPLPAIIGHDISGVIEEVGS MAB_1486c|M.abscessus_ATCC_199 LINVKAAGVNPIDWKLY-----SGAFGTDPDKLPMRLGLEISGTIAAVGA Mb3806|M.bovis_AF2122/97 LIKVAASGVNRADVLQA-----AGKYPPPPG-VSDIIGLEVSGIVAAVGP Rv3777|M.tuberculosis_H37Rv LIKVAASGVNRADVLQA-----AGKYPPPPG-VSDIIGLEVSGIVAAVGP MLBr_00118|M.leprae_Br4923 LIEVAASGVNRADVLQV-----AGKYPHPPG-ASAIIGMEVAGVVAAVSS TH_1665|M.thermoresistible__bu LIAVHTAGINRADLLQA-----AGKYPPPPG-ASEILGLEVSGTVAAVGA MUL_2209|M.ulcerans_Agy99 RVQVQAIGVNPVDWKMRSSGPLRLAARLIGPKPPVVVGVDFAGVVEAVGP MSMEG_5164|M.smegmatis_MC2_155 LVRVEAVSVNPVDIKRR--------RSLSPSAEPTILGFDAAGVVEAVGS : * : .:* * :* : :* : *.. MMAR_3099|M.marinum_M QVSGVGVGDAVMGLIAGVG-------PLAVVDARLLVRVPSGWSLAEAAG MAV_3108|M.avium_104 GVTDVAVGDAVMGIFGLVG-------SEAAVDRRLVTRVPPGWSMAQAAG Mvan_5758|M.vanbaalenii_PYR-1 RVDRFTVGDEVFGMTGGVGGLQGSLAELAAVDARLIAHKPRTLSMAQAAA Mflv_2124|M.gilvum_PYR-GCK HVTEFRAGDAVYYTPKIFGG-PGSYAEQHVADVDLVGRKPDNLDHLEAAS MAB_1486c|M.abscessus_ATCC_199 GVDGLVPGDDVIAAGQIGG-----YATRVIAAADQVFKKPASLSFNEAAG Mb3806|M.bovis_AF2122/97 GVTEWSAGQEVCALLAGGG-----YAEYVAVPADQVLPIPPSVNLVDSAA Rv3777|M.tuberculosis_H37Rv GVTEWSAGQEVCALLAGGG-----YAEYVAVPADQVLPIPPSVNLVDSAA MLBr_00118|M.leprae_Br4923 GVTEWSVGQEVCALLAGGG-----YAEYVAVPASQVMPIPKGVNVVDSAG TH_1665|M.thermoresistible__bu GVSGWTVGQPVCALLAGGG-----YAEYVAVPAEQVMPIPESVEIRYAAA MUL_2209|M.ulcerans_Agy99 GVTRAAPGDRVVGGTNFSRGQRGSYADTVLVREDQLCRVPDTVDIAVAAA MSMEG_5164|M.smegmatis_MC2_155 EVTTLSVGDEVWYAGDVSRP--GTNAQLHAVDERIVARKPRSLSFRDAAA * *: * . : * . :*. MMAR_3099|M.marinum_M VPVAFLTAWYGLADLAGVR----AGESVLVHAGTGGVGMAAVQLARLWG- MAV_3108|M.avium_104 IPVVFLTAYYGLSVLAGLR----AGQRVLVHAATGGVGMAAVQLARHWG- Mvan_5758|M.vanbaalenii_PYR-1 LPLGFITSWEGLVDRAGVG----TGQQVLIHGGAGGVGFLAVQLALARG- Mflv_2124|M.gilvum_PYR-GCK LTLVGGTVWESLVTRAQLT----VGETILIHGGAGGVGTIAIQVAKAMG- MAB_1486c|M.abscessus_ATCC_199 FLLTG-QTAVHLLEATNVT----EGDTVLIHGAAGGVGLLATQLAKARG- Mb3806|M.bovis_AF2122/97 LPEVACTVWSNLVMTAHLR----PGQLVLIHGGASGIGSHAIQVARALA- Rv3777|M.tuberculosis_H37Rv LPEVACTVWSNLVMTAHLR----PGQLVLIHGGASGIGSHAIQVVRALA- MLBr_00118|M.leprae_Br4923 IPEVACTVWSNLVMAAHLS----AGQLLLLHGGTSGIGSHGIQVARALG- TH_1665|M.thermoresistible__bu LPEVACTVWSNLVMTAGLS----AGEWVLIHGGASGVGSHAVQVARALD- MUL_2209|M.ulcerans_Agy99 LPVGGVTAWMAVVELGRIRQVPSADRRVLVLGASGGVGQLAVQIAKLQE- MSMEG_5164|M.smegmatis_MC2_155 LPLTTITAWETLFERFNLTAD--SRGDLLVLGAAGGVGSVMIQLAKKLTG . : : :*: ..:.*:* *:. MMAR_3099|M.marinum_M AKVFVTASR-GKWDTLRSMGFDDSRIGDSRSLEFAEKFFAATRGRG-VDV MAV_3108|M.avium_104 AEVFATASR-GKWDTLRAMGFDDAHIADSRTLDFEQKFGAAPGG---MDV Mvan_5758|M.vanbaalenii_PYR-1 AQVYATGST-SSQAVIRAAGAVP---IDYTATTVDEYVAAHTGGEG-FDV Mflv_2124|M.gilvum_PYR-GCK ARVITTAKA-GDHAFVNSLGADVA--IDHTSTDYVDAVAEATRGRG-VDV MAB_1486c|M.abscessus_ATCC_199 ATVVATASA-ARHDQLRGYGA--------LPVEYGPGLQERVSAIGPVDA Mb3806|M.bovis_AF2122/97 ARVAITAGSPEKLELCRDLGAQIT--INYRDEDFVARLKQETDGSG-ADI Rv3777|M.tuberculosis_H37Rv ARVAITAGSPEKLELCRDLGAQIT--INYRDEDFVARLKQETDGSG-ADI MLBr_00118|M.leprae_Br4923 AKVAVTAGSEEKLEFCRALGAQIT--INYRDEDFVARLQQQN--GG-ADV TH_1665|M.thermoresistible__bu ARVAVTAGTRHKLELCRELGAEVT--ICYREEDFVERVRAETDGAG-ADV MUL_2209|M.ulcerans_Agy99 AFVVGVCST-ENVEMVKDLGADLV-----LDYNQGDALAQAKPHAP-FHV MSMEG_5164|M.smegmatis_MC2_155 VRVIATASRDESRQWARDLGADEV-----IDHHDLRTQALDVAPDG-VDY . * . . * . MMAR_3099|M.marinum_M VLNSLAGEFVDASLRLLAPGGRFIEMGKTDIRDPQQIAVEYPGVIYEAFD MAV_3108|M.avium_104 VLNSLAGEFNDASLRLLGPGGRFIEMGKTDLRDPDVVARAHPGVRYRAFD Mvan_5758|M.vanbaalenii_PYR-1 VADNVGGATLDASFTAVKR------------------------------- Mflv_2124|M.gilvum_PYR-GCK VFDTIGGDTLTRSPLSLADS------------------------------ MAB_1486c|M.abscessus_ATCC_199 ALDLVGTDEAADVSLALVADK----------------------------- Mb3806|M.bovis_AF2122/97 ILDIMGASYLDRNIDALATDG----------------------------- Rv3777|M.tuberculosis_H37Rv ILDIMGASYLDRNIDALATDG----------------------------- MLBr_00118|M.leprae_Br4923 ILDIMGAAYLDRNIDALAIDG----------------------------- TH_1665|M.thermoresistible__bu VLDIMGAAYLGRNVDALATDG----------------------------- MUL_2209|M.ulcerans_Agy99 VIDCVGSYSGAGCRALLSSRG----------------------------- MSMEG_5164|M.smegmatis_MC2_155 LFTPFSAGNVDVFADIVRPFG----------------------------- .. : MMAR_3099|M.marinum_M LIEAGPARIQPMLGQLHTLFEASALESLPTRTWDARCAPAAYRFVSQARQ MAV_3108|M.avium_104 LMEAGPDRIAAMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARH Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M IGKVVLTMPTQISDAVAAGTVLITGGTGMVASVLARHLVSSYGVKHVVLA MAV_3108|M.avium_104 IGKVVLTMPDGP-AGLSGGTALITGATGMAGAALARHLVARHRVPHLMLV Mvan_5758|M.vanbaalenii_PYR-1 -------------------------YTGHVVSALG------WGTHSLAPL Mflv_2124|M.gilvum_PYR-GCK ---------------------------GRVVSIVD-----------IARP MAB_1486c|M.abscessus_ATCC_199 ---------------------------GRIATIAG-----------FGRA Mb3806|M.bovis_AF2122/97 --------------------------QLIVIGMQG---------GVKAEL Rv3777|M.tuberculosis_H37Rv --------------------------QLIVIGMQG---------GVKAEL MLBr_00118|M.leprae_Br4923 --------------------------QLIVIGLQG---------GVKGEL TH_1665|M.thermoresistible__bu --------------------------RLVVIGMQG---------GRRAEL MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 ----------------------------HITAIDE-----------PEGL MMAR_3099|M.marinum_M SRRADATAGVAELVADLAAAGAAVAVVACDVADRAAVTRLLDHVSTCHPP MAV_3108|M.avium_104 GRRGEAAPGMAELAAELRGAGASVSVLSCDVGDRDAVAAMLAQVPARYP- Mvan_5758|M.vanbaalenii_PYR-1 SFRGAAYSGVFTLMPLLTGRGR------DHHGEIVAEAAALADSGRLAPR Mflv_2124|M.gilvum_PYR-GCK QNLIEAWGRNAAYHFVFTRQNRGKLDALTMLVERGLVKPVLGATLPLARM MAB_1486c|M.abscessus_ATCC_199 ASDGFKALGGGPGADPGTEIRLAARPELIRLAGNGELKVTVDRTYPLSDA Mb3806|M.bovis_AF2122/97 NLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVRP Rv3777|M.tuberculosis_H37Rv NLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVRP MLBr_00118|M.leprae_Br4923 NLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVRP TH_1665|M.thermoresistible__bu DLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQVRP MUL_2209|M.ulcerans_Agy99 -RHIMVAGDEPSSAVQVVVPPFKSKAILGRPNGARLEPLVDAVAAGKLRV MSMEG_5164|M.smegmatis_MC2_155 DLVGLKTKSIAWHWELMFTRPLTGYDIAAQQRLLADAADLVDRGELRTTL MMAR_3099|M.marinum_M LTGVI-HAAGTLDDAVIASLTPDRVDAVLRAKVDGAWNLHEATRHLGLSM MAV_3108|M.avium_104 LRSVF-HAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSA Mvan_5758|M.vanbaalenii_PYR-1 LHPTT-FPLDAVNDAHTAVESGSATGKVVVEPNV---------------- Mflv_2124|M.gilvum_PYR-GCK GEAHE-LLENRRSYALRGKVAIDVAGETVALPPRIS-------------- MAB_1486c|M.abscessus_ATCC_199 RQAHE-YGQTG-----------HARGKIILLP------------------ Mb3806|M.bovis_AF2122/97 VIGTR-LPIQQAAQAHELMLSGKTFGKILLTV------------------ Rv3777|M.tuberculosis_H37Rv VIGTR-LPIQQAAQAHELMLSGKTFGKILLTV------------------ MLBr_00118|M.leprae_Br4923 IIGAR-MAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH----- TH_1665|M.thermoresistible__bu VVGAE-FPIQEAQAAHELLASGDVYGKVLLCVED---------------- MUL_2209|M.ulcerans_Agy99 SIAQK-LPLTSAEEAHRLSQTSRMTGKLILEP------------------ MSMEG_5164|M.smegmatis_MC2_155 TTAIDGFTAANLREAHRMVESGRMVGKVVVSR------------------ . : MMAR_3099|M.marinum_M FVLCSSIAATVGSSGQANYAAGNAFLDGLAAYRRAGGLPGMSLGWGLWEQ MAV_3108|M.avium_104 FVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M SSTMTAHLSDRDMARIRRIGLAAISPEQAMQLFDAALAVGQPTVLAAHLD MAV_3108|M.avium_104 PSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLD Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M HAVLANHTLSSTLPPLFSTLIKRPLRRLVDNDTPSSTAGFAQRLYGLKPE MAV_3108|M.avium_104 RAALAQH--RAALPPLLSELAGRPARRMLEHTDMVSLTGLRARLAGMNPE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M KQQDLLVDLVCTQAAAVLGHPSATDLNPASTFQNMGFDSLTAVELRNRLK MAV_3108|M.avium_104 QRQAELVELVCGNAAAVLGH-STADVDPGDAFSDLGFDSLTAVELRNRLK Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M TVTGLGLSPTLVFDHPTPTALAG-LIAELIGIAAKGLSPLEEALN----- MAV_3108|M.avium_104 IATGLTLSPTVIFDHPTPAALAEHLGGQLTSAGPTPAAPAETAAPPDRSS Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M ---------NVEETLPAIEAGDKHRVADRLRALLSTITDEEHRLDERIQA MAV_3108|M.avium_104 RIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSG--HPEFPE Mvan_5758|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2124|M.gilvum_PYR-GCK -------------------------------------------------- MAB_1486c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3806|M.bovis_AF2122/97 -------------------------------------------------- Rv3777|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- TH_1665|M.thermoresistible__bu -------------------------------------------------- MUL_2209|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3099|M.marinum_M ASTLDEVLLLVDSELANLEKGPGL- MAV_3108|M.avium_104 DAFDDDIATATDSQLFAILDDEAGP Mvan_5758|M.vanbaalenii_PYR-1 ------------------------- Mflv_2124|M.gilvum_PYR-GCK ------------------------- MAB_1486c|M.abscessus_ATCC_199 ------------------------- Mb3806|M.bovis_AF2122/97 ------------------------- Rv3777|M.tuberculosis_H37Rv ------------------------- MLBr_00118|M.leprae_Br4923 ------------------------- TH_1665|M.thermoresistible__bu ------------------------- MUL_2209|M.ulcerans_Agy99 ------------------------- MSMEG_5164|M.smegmatis_MC2_155 -------------------------