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MLTAHAIKVHESGGPDVLVNEEIDVPEPGSGQVLVRNEAIGLNFLDTYLRSGRYAAETPFVPGHEGAGVV ERVGAGVTDIGVGDRVGYIDPIGAYADLVVRPADRVIPLPPGISTRLAAGMLMKGMTSEYLVRRTYPVRQ GQTILVHAAAGGVGQILCQWARYLGATVIGTVGSAAKRQIAANAGCEHVIVNDEEDLVAAVRDITAGRGV PVVYDGVGGDGFAKSLDCLAPLGTLVAFGAASGPIPPLDVQTLGPKGSLYVTRPMIGPYVATTAELRASA QALFELVLDGYIEVDIANSYPLTEAAGAHADLEARKLTGSTVLIP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4146 | - | - | 100% (325) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3106 | - | 1e-79 | 47.08% (325) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2033 | - | 3e-37 | 36.83% (315) | oxidoreductase, zinc-binding dehydrogenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1489c | qor | 2e-79 | 47.71% (327) | quinone reductase |
| M. gilvum PYR-GCK | Mflv_3686 | - | 1e-80 | 47.73% (331) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv1454c | qor | 2e-79 | 47.71% (327) | quinone reductase |
| M. leprae Br4923 | MLBr_00118 | - | 5e-27 | 30.89% (327) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_3622c | - | 3e-84 | 49.06% (320) | putative quinone oxidoreductase |
| M. marinum M | MMAR_2259 | qor | 4e-77 | 46.65% (328) | quinone reductase Qor |
| M. avium 104 | MAV_3325 | - | 2e-78 | 47.06% (323) | quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_3440 | - | 2e-83 | 50.00% (322) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_1855 | qor | 4e-75 | 46.04% (328) | quinone reductase Qor |
| M. vanbaalenii PYR-1 | Mvan_2724 | - | 4e-80 | 47.99% (323) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4146|M.smegmatis_MC2_155 --------------------------------------------MLTAHA
MAB_3622c|M.abscessus_ATCC_199 ----------------------------------------------MAYA
Mb1489c|M.bovis_AF2122/97 -----------------------------------------------MHA
Rv1454c|M.tuberculosis_H37Rv -----------------------------------------------MHA
MMAR_2259|M.marinum_M ----------------------------------------MVGHDSGVHA
MUL_1855|M.ulcerans_Agy99 ----------------------------------------MVGHDSGVHA
MAV_3325|M.avium_104 -----------------------------------------------MHA
Mflv_3686|M.gilvum_PYR-GCK --------------------------------------------MVDMYA
Mvan_2724|M.vanbaalenii_PYR-1 -----------------------------------------------MYA
TH_3440|M.thermoresistible__bu VQTAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKA
MLBr_00118|M.leprae_Br4923 -----------------------------------------------MHA
*
MSMEG_4146|M.smegmatis_MC2_155 IKVHESGGPDVLVNEEIDVPEPGSGQVLVRNEAIGLNFLDTYLRSGRYAA
MAB_3622c|M.abscessus_ATCC_199 VRIHETGGPEVLRGENVQVGAPGPGEVRIRHHAVGLNFADVYFRTGVYPV
Mb1489c|M.bovis_AF2122/97 IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
Rv1454c|M.tuberculosis_H37Rv IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
MMAR_2259|M.marinum_M IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MUL_1855|M.ulcerans_Agy99 IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MAV_3325|M.avium_104 IEVSETGGPEVLRYVETPTPTAGPGQVLIKAEAIGVNYIDTYFRSGQYPR
Mflv_3686|M.gilvum_PYR-GCK IEVAETGGPEVLSFVETSRPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
Mvan_2724|M.vanbaalenii_PYR-1 IEVAETGGPEVLSFVERPQPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
TH_3440|M.thermoresistible__bu IEVRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
MLBr_00118|M.leprae_Br4923 IVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGKYPH
: .:. : : .* *:: :. * *:* *. :* *.
MSMEG_4146|M.smegmatis_MC2_155 --ETPFVPGHEGAGVVERVGAGVT-----DIGVGDRVGYID-PIGAYADL
MAB_3622c|M.abscessus_ATCC_199 --ALPAGMGVAGSGIIEAVGPGVS-----QFGPGDRVTYTGSPLGAYSTE
Mb1489c|M.bovis_AF2122/97 --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSAS-ANGAYAEF
Rv1454c|M.tuberculosis_H37Rv --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSAS-ANGAYAEF
MMAR_2259|M.marinum_M --ELPFVIGSEVCGTVVALGPGATAADAGGIAVGDRVVSAS-ANGGYAEF
MUL_1855|M.ulcerans_Agy99 --ELPFVIGSEVCGTVVAVGPGATAADAGGIAVGDRVVSAS-ANGGYAEF
MAV_3325|M.avium_104 --ELPFIIGQELCGTVAAAGDGVD-----GFKVGDRVVSAA-ATGGYAEY
Mflv_3686|M.gilvum_PYR-GCK --ETPFIAGSEVCGVIEEVGEDVA-----ALNVGDRVVTTQ-SQGAYAEY
Mvan_2724|M.vanbaalenii_PYR-1 --EVPFVVGTEVCGVIEAVGEGVA-----ALKVGDRVVTDK-SLGAYAEY
TH_3440|M.thermoresistible__bu --EVPFIVGTEVCGTVEAVGDGVA-----ALRVGDRVLTDK-ANGAYAEY
MLBr_00118|M.leprae_Br4923 PPGASAIIGMEVAGVVAAVSSGVT-----EWSVGQEVCALL-AGGGYAEY
. * .* : . .. *:.* . *.*:
MSMEG_4146|M.smegmatis_MC2_155 VVRPADRVIPLPPGISTRLAAGMLMKGMTSEYLVRRTYPVRQGQTILVHA
MAB_3622c|M.abscessus_ATCC_199 RVMPAAHLIGLPDGISCDTAAAITMRGLTTAYLLRRIHPLRAGDTVLLHA
Mb1489c|M.bovis_AF2122/97 CTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHA
Rv1454c|M.tuberculosis_H37Rv CTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHA
MMAR_2259|M.marinum_M CTAPAALTAKVPDGVSAEVAASALLKGLTAHYLLKSVYPVADGDAILVHA
MUL_1855|M.ulcerans_Agy99 CTAPAALTAKVPDVVSAEVAASALLKGLTAHYLLKSVCPVADGDAILVHA
MAV_3325|M.avium_104 ATAPASLTAHVPDGVAADVAASALLKGLTAHYLLTSVYPVQAGDTVLVHA
Mflv_3686|M.gilvum_PYR-GCK CVAPADFVAYVPDAVAPEVAASALLKGMTAHYLLKSTYPVQQGDAILVHA
Mvan_2724|M.vanbaalenii_PYR-1 CLAPADFVAYVPDGVAPEVAASALLKGMTAHYLIKSTYPVQQGDVVLLHA
TH_3440|M.thermoresistible__bu TVAPADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHA
MLBr_00118|M.leprae_Br4923 VAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHG
** :* : *. . * : : *: :*:*.
MSMEG_4146|M.smegmatis_MC2_155 AAGGVGQILCQWARYLGATVIGTVGSAAKRQIAANAGCEHVIVNDEE---
MAB_3622c|M.abscessus_ATCC_199 AAGGVGLLFLQWANLLGVNVIGTVSNEEKAEIARANGCAHVLIYPRE---
Mb1489c|M.bovis_AF2122/97 GAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED---
Rv1454c|M.tuberculosis_H37Rv GAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED---
MMAR_2259|M.marinum_M GAGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGAAEVLDYPTD---
MUL_1855|M.ulcerans_Agy99 GAGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGATEVLDYPTD---
MAV_3325|M.avium_104 GAGGVGLILTQWAHLLGARVITTVSTPEKARRSAQAGANEVLSYPDD---
Mflv_3686|M.gilvum_PYR-GCK GAGGVGLLLTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPSQDAG
Mvan_2724|M.vanbaalenii_PYR-1 GAGGVGLILTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPDD---
TH_3440|M.thermoresistible__bu GAGGVGLILTQWATHLGARVITTVSTPQKAELSRKAGAAEVLDYPTD---
MLBr_00118|M.leprae_Br4923 GTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDE---
.:.*:* * * *.. * *... * . . *. .: :
MSMEG_4146|M.smegmatis_MC2_155 ---DLVAAVRDITAGRGVPVVYDGVGGDGFAKSLDCLAPLGTLVAFGAAS
MAB_3622c|M.abscessus_ATCC_199 ---DVPRRVREITGGVGVPVVYDGIGKATYQSSLDSLSPRGLLVCFGTAS
Mb1489c|M.bovis_AF2122/97 -AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAAS
Rv1454c|M.tuberculosis_H37Rv -AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAAS
MMAR_2259|M.marinum_M -AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAAS
MUL_1855|M.ulcerans_Agy99 -AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAAS
MAV_3325|M.avium_104 -ADEFGNRIRALTDGAGVAAVYDGVGASTFDASLASLAVRGTLALFGAAS
Mflv_3686|M.gilvum_PYR-GCK GAAAFGDRIRELTDGDGVAAVYDGVGASTFEASLASLAIRGTLALFGAAS
Mvan_2724|M.vanbaalenii_PYR-1 -PKAFGDRIRELTDGDGVAAVFDGVGASTFEASLASLAVRGTLALFGAAS
TH_3440|M.thermoresistible__bu -PEEFGARIRDLTGGEGVPVVYDGVGRSTFDASLASLAVRGTLALFGAAS
MLBr_00118|M.leprae_Br4923 ---DFVARLQQQNG--GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQG
. :: . *. .: * :* .: .*: * * :* .
MSMEG_4146|M.smegmatis_MC2_155 GPIPPLDVQTLGPK-----GSLYVTRPMIGPYVATTAELRASAQALFELV
MAB_3622c|M.abscessus_ATCC_199 GPIPSIDAMQLAAK-----GSLFVTRPALADYIADPAERAELAGELFGHV
Mb1489c|M.bovis_AF2122/97 GPVPPVDPQRLNAA-----GSVYLTRPSLFHFTRTGEEFSWRAAELFDAI
Rv1454c|M.tuberculosis_H37Rv GPVPPVDPQRLNAA-----GSVYLTRPSLFHFTRTGEEFSWRAAELFDAI
MMAR_2259|M.marinum_M GPVPPVDPQRLNAA-----GSVYLTRPSLFHFIRTAEEFSWRASELFDAI
MUL_1855|M.ulcerans_Agy99 GPVPPVEPQRLNAA-----GSVYLTRPSLFHFIRTAEEFSWRASELFDAI
MAV_3325|M.avium_104 GPVPPFDPQRLNAA-----GSVFLTRPSLAHFIRTGQEFSWRAEELFAAI
Mflv_3686|M.gilvum_PYR-GCK GPVPPIDPQRLNTA-----GSVFLTRPNLAHHTRTPDEFSWRAGELLTAI
Mvan_2724|M.vanbaalenii_PYR-1 GPVPPVDPQRLNAA-----GSVYLTRPNLAHYTRTPDEFSWRAGELLTAI
TH_3440|M.thermoresistible__bu GPVPPFDPQRLNAA-----GSVYLTRPSLVHFTRTPDEFGWRAGEFLSAV
MLBr_00118|M.leprae_Br4923 GVKGELNLGKVLSKRARIIGSTLRARPVNGPNSKS-EIVAAVTASIWPMI
* .: : . ** :** : : :
MSMEG_4146|M.smegmatis_MC2_155 LDGYIEVDIANSYPLTEAAGAHADLEARKLTGSTVLIP------------
MAB_3622c|M.abscessus_ATCC_199 GAGRIRVDIGRRYSLEEAVTAHRDMESGAIIGQSIFAL------------
Mb1489c|M.bovis_AF2122/97 GSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP------------
Rv1454c|M.tuberculosis_H37Rv GSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP------------
MMAR_2259|M.marinum_M SSGVITIEVGGRYRLADAMKAHQDLEARKTIGSVVLLP------------
MUL_1855|M.ulcerans_Agy99 SSGVITIEVGGRYRLADAMKAHQDLEARKTIGSAVLLP------------
MAV_3325|M.avium_104 AAGDITVEVGGRYPLADAARAHRDLQGRKTTGSIVLLP------------
Mflv_3686|M.gilvum_PYR-GCK ADGALTVTVSNRYALREAEQAHRDLQGRRTVGSVVLIP------------
Mvan_2724|M.vanbaalenii_PYR-1 ADGTLDVTVSHRYALRDAEQAHRDLQGRKTVGSVVLLP------------
TH_3440|M.thermoresistible__bu ADGTLTITVGERYPLAEAERAHRDLEGRKTVGSVVLLP------------
MLBr_00118|M.leprae_Br4923 ADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRH
: :. : :* ** : . *. ::
MSMEG_4146|M.smegmatis_MC2_155 -
MAB_3622c|M.abscessus_ATCC_199 -
Mb1489c|M.bovis_AF2122/97 -
Rv1454c|M.tuberculosis_H37Rv -
MMAR_2259|M.marinum_M -
MUL_1855|M.ulcerans_Agy99 -
MAV_3325|M.avium_104 -
Mflv_3686|M.gilvum_PYR-GCK -
Mvan_2724|M.vanbaalenii_PYR-1 -
TH_3440|M.thermoresistible__bu -
MLBr_00118|M.leprae_Br4923 H