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HAIVAESANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGKYPHPPGASAIIGMEVAGVVAAVSS GVTEWSVGQEVCALLAGGGYAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLL LHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDFVARLQQQNGGADVILDIM GAAYLDRNIDALAIDGQLIVIGLQGGVKGELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASI WPMIADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00118 | - | - | 100% (336) | putative oxidireductase |
| M. leprae Br4923 | MLBr_02355 | - | 2e-33 | 31.15% (305) | polyketide synthase |
| M. leprae Br4923 | MLBr_01229 | pks3 | 1e-32 | 28.85% (312) | mycocerosic acid synthase (polyketide synthase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3806 | - | 1e-142 | 76.31% (325) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1189 | - | 1e-118 | 64.29% (322) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3777 | - | 1e-142 | 76.00% (325) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0207c | - | 1e-103 | 54.74% (327) | quinone oxidoreductase |
| M. marinum M | MMAR_5332 | - | 1e-140 | 73.70% (327) | oxidoreductase |
| M. avium 104 | MAV_0242 | - | 1e-145 | 77.71% (323) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6362 | - | 1e-124 | 65.43% (324) | quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_1665 | - | 1e-117 | 61.85% (325) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_0096 | - | 1e-139 | 73.39% (327) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5615 | - | 1e-118 | 63.27% (324) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00118|M.leprae_Br4923 ---MHAIVAESANQ---MVWREVPDVTAGPGEVLIEVAASGVNRADVLQV
MAV_0242|M.avium_104 MATMRAIVAESADQ---LSWQEVADVSAGPGEVVVKVAAAGVNRADVLQA
Mb3806|M.bovis_AF2122/97 MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
Rv3777|M.tuberculosis_H37Rv MTIMRAVVAESSDR---LVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
MMAR_5332|M.marinum_M MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MUL_0096|M.ulcerans_Agy99 MAFVHAIVAESADH---LVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MSMEG_6362|M.smegmatis_MC2_155 ---MHAIVASVNGG---LNWENVASIAPANGEVLIKVHTAGINRADLLQA
Mflv_1189|M.gilvum_PYR-GCK -------MAETPDQ---LNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA
Mvan_5615|M.vanbaalenii_PYR-1 --MHAIVAQPSSEG---LTWQSVPDIAPAPGEVLIRVAAAGVNRADLLQA
TH_1665|M.thermoresistible__bu ---MRAISVQTSGQ---LSWVEVPDIEPGESEVLIAVHTAGINRADLLQA
MAB_0207c|M.abscessus_ATCC_199 ---MHAITVDNPGGPEALRWTEVPDPVPGPGEILIDVTAAAANRADLLQR
: * .*.. .. .*::: * ::. ****:**
MLBr_00118|M.leprae_Br4923 AGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAEY
MAV_0242|M.avium_104 AGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGGYAEY
Mb3806|M.bovis_AF2122/97 AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
Rv3777|M.tuberculosis_H37Rv AGKYPPPPGVSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAEY
MMAR_5332|M.marinum_M AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MUL_0096|M.ulcerans_Agy99 AGKYPPPPGASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAEY
MSMEG_6362|M.smegmatis_MC2_155 AGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGGYAEY
Mflv_1189|M.gilvum_PYR-GCK AGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGGYAEY
Mvan_5615|M.vanbaalenii_PYR-1 AGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGGYAEF
TH_1665|M.thermoresistible__bu AGKYPPPPGASEILGLEVSGTVAAVGAGVSGWTVGQPVCALLAGGGYAEY
MAB_0207c|M.abscessus_ATCC_199 RGLYSPPPGASSILGLECSGTVAALGADVAHWSVGQPVCALLSGGGYAEK
* *. ***.* :*:* :* : :. .*: *: ** *****:******
MLBr_00118|M.leprae_Br4923 VAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHG
MAV_0242|M.avium_104 VAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLLLVHG
Mb3806|M.bovis_AF2122/97 VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
Rv3777|M.tuberculosis_H37Rv VAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIHG
MMAR_5332|M.marinum_M VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MUL_0096|M.ulcerans_Agy99 VAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIHG
MSMEG_6362|M.smegmatis_MC2_155 VAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLLLVHG
Mflv_1189|M.gilvum_PYR-GCK VAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELLLIHG
Mvan_5615|M.vanbaalenii_PYR-1 VAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELLLVHG
TH_1665|M.thermoresistible__bu VAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLVMTAGLSAGEWVLIHG
MAB_0207c|M.abscessus_ATCC_199 VVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMMMTTKMSAGQSILIHG
*..** *::*:* .* : :*.:**********::: : : . :*:**
MLBr_00118|M.leprae_Br4923 GTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDFV
MAV_0242|M.avium_104 GASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRDEDFV
Mb3806|M.bovis_AF2122/97 GASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
Rv3777|M.tuberculosis_H37Rv GASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQITINYRDEDFV
MMAR_5332|M.marinum_M GASGIGSHAIQVCTALGARVAVTAGSSEKLQLCRDLGAQITINYRDEDFV
MUL_0096|M.ulcerans_Agy99 GACGIGSHAIQVCTALGARVAVTAGSSEKLQLSRDLGAQITINYRDEDFV
MSMEG_6362|M.smegmatis_MC2_155 GASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYREEDFV
Mflv_1189|M.gilvum_PYR-GCK GASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHHEDFV
Mvan_5615|M.vanbaalenii_PYR-1 GASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHNEDYV
TH_1665|M.thermoresistible__bu GASGVGSHAVQVARALDARVAVTAGTRHKLELCRELGAEVTICYREEDFV
MAB_0207c|M.abscessus_ATCC_199 GASGIGTHTIQVAKALGLRVAVTAGTPEKLDACRDLGADLAINYRDTDFV
*:.*:*:* :** *: :**:***: .** . ***:::* *:. *:*
MLBr_00118|M.leprae_Br4923 ARLQQQN---GGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKGE
MAV_0242|M.avium_104 ARLADET---GGADVILDIMGAAYLDRNIDALATDGQLVIIGMQGGVKAE
Mb3806|M.bovis_AF2122/97 ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
Rv3777|M.tuberculosis_H37Rv ARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKAE
MMAR_5332|M.marinum_M ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MUL_0096|M.ulcerans_Agy99 ARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKAE
MSMEG_6362|M.smegmatis_MC2_155 ERLRRET---DGADVILDIMGAAYLDRNVDALATGGRLVIIGMQGGVKAE
Mflv_1189|M.gilvum_PYR-GCK EVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGGTKAE
Mvan_5615|M.vanbaalenii_PYR-1 GVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGGAKAE
TH_1665|M.thermoresistible__bu ERVRAETDG-AGADVVLDIMGAAYLGRNVDALATDGRLVVIGMQGGRRAE
MAB_0207c|M.abscessus_ATCC_199 QAVHSFTDG-SGVDRILDIMGAKYLSRNVDALGNDGHLVIIGMQGGVTAE
: *.* :****** **.**:::*. .*:*::**:*** .*
MLBr_00118|M.leprae_Br4923 LNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVR
MAV_0242|M.avium_104 LNIGKLLAKRARVIGTTLRGRPVSGPNSKTEIVQAVTASVWPMIADGRVR
Mb3806|M.bovis_AF2122/97 LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
Rv3777|M.tuberculosis_H37Rv LNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRVR
MMAR_5332|M.marinum_M LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MUL_0096|M.ulcerans_Agy99 LNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRVR
MSMEG_6362|M.smegmatis_MC2_155 LNIGKLLGKRAGVIATSLRPRPVDGPGGKGEIVRAVRENVWPMIADGRVK
Mflv_1189|M.gilvum_PYR-GCK INLGKLLAKRGSVMATALRSRPVTGRGSKSVIVSEVIENVWPLVADGQVR
Mvan_5615|M.vanbaalenii_PYR-1 LNIGKLLTKRGSVIATALRSRPVHGRGGKADIVARVGAELWPLVADGQVR
TH_1665|M.thermoresistible__bu LDLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQVR
MAB_0207c|M.abscessus_ATCC_199 LNIAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLVEAGKVR
:::.*:: **. : .::** **: * .* *. * .:**:: . *:
MLBr_00118|M.leprae_Br4923 PIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
MAV_0242|M.avium_104 PIIGARLPIQQAGDAHRRLVASEVTGKIVLTV-------------
Mb3806|M.bovis_AF2122/97 PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
Rv3777|M.tuberculosis_H37Rv PVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
MMAR_5332|M.marinum_M PIIGSRLPIGQAAQAHQLLLSGQSYGKTLLTVDG-----------
MUL_0096|M.ulcerans_Agy99 PIIGSRLPIGQAAQAHQLLLSGQSYGKILLTVDG-----------
MSMEG_6362|M.smegmatis_MC2_155 PIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE-----------
Mflv_1189|M.gilvum_PYR-GCK PVIGAEFPISEAQAAHELLASGDVSGKVILRVDV-----------
Mvan_5615|M.vanbaalenii_PYR-1 PVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV-----------
TH_1665|M.thermoresistible__bu PVVGAEFPIQEAQAAHELLASGDVYGKVLLCVED-----------
MAB_0207c|M.abscessus_ATCC_199 PVVGAEIPLSQAAEAHRLLENGAVVGKVLLTR-------------
*::*:.:.: :* .* : . ** :*