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MTTVENAKRIIPGSPQWSALLAKIAAGARDRDLGDENPFDEVNALKRAGFGTLRLPESLGGAGFTVPQLF SAVIDVAQADPIVAHIFRTHFWFTEERLRTSSDPVSQRWLREIADGKIFGNAFSEKGSLAVGSLVFNTRL LPDPADPGALRLNGEKFYSTGTLFADYLTVTATTDHDSVANVVIPADREGVRLVDDWDGFGQRRTGTGTT VLTDVAVSPEEVLTDSPYDADPVPTVQYASLQLFIHAVVAGILANVVDDGVALLRSRERNFSHAVAERPT DDPLLQRQLGVLASTAYVARAAVLDAAAAIGAATDSAKDGVPDADLAAEAQLKVAKVKVHLDDIAPEAAT RLLELGGASAASRQRGLDRHWRNIRTITLHNPVAYKARVIGQNLLHGTPVPANAYF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5001 | - | - | 100% (406) | pesticide degrading monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4391 | - | 5e-80 | 41.21% (398) | acyl-CoA dehydrogenase-family protein |
| M. smegmatis MC2 155 | MSMEG_3259 | - | 6e-77 | 41.13% (389) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1706 | fadE16 | 1e-09 | 22.16% (352) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4370 | - | 3e-10 | 22.31% (372) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1679 | fadE16 | 1e-09 | 22.16% (352) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 7e-10 | 23.73% (375) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1422c | - | 1e-167 | 73.12% (398) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_4034 | fadE | 5e-11 | 22.55% (377) | acyl-CoA dehydrogenase FadE |
| M. avium 104 | MAV_3422 | - | 4e-83 | 42.93% (396) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_3721 | - | 1e-49 | 39.45% (289) | PUTATIVE putative acyl-CoA dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_2626 | fadE25 | 1e-09 | 22.61% (376) | acyl-CoA dehydrogenase FadE25 |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 2e-36 | 29.49% (390) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5001|M.smegmatis_MC2_155 -----------MTTVEN--AKRIIPGSPQWSALLAKIAAGARDR--DLGD
MAB_1422c|M.abscessus_ATCC_199 -----------MTSAPSVLEIRALPGTDTYRNLLAQVAEGARDR--DLDD
MAV_3422|M.avium_104 -----------MPVAFH--RQDTPAGAAAVQPVLAEIAADYRLRLADGGT
TH_3721|M.thermoresistible__bu --------------VPYFDEQRFEALAAEFRPVFDRIRAGAVQR--ERDR
Mb1706|M.bovis_AF2122/97 ------------------------MATPGVVQEVVSVAAEHAER-VDTDC
Rv1679|M.tuberculosis_H37Rv ------------------------MATPGVVQEVVSVAAEHAER-VDTDC
Mflv_4370|M.gilvum_PYR-GCK MASPPANAAEAGIPSAEVNDEDFQAILAATREFVRTAVVPREQE-ILSTD
MMAR_4034|M.marinum_M MTAP------------QVSDEDFAQILAQTRHFVRSVVLPREQQ-ILDED
MLBr_00737|M.leprae_Br4923 MVGWSGNPL----FDLFKLPEEHNELRATIRALAEKEIAPHAAD-VDQRA
MUL_2626|M.ulcerans_Agy99 MAGWAGNPS----FDLFQLPEEHQELRAAIRALAEKEIAPHAAD-VDENS
Mvan_3173|M.vanbaalenii_PYR-1 ------MATDITDRIPDTLLRTPADALAAAEEVAEAIAAGSAER--ERAG
MSMEG_5001|M.smegmatis_MC2_155 ENPFDEVNALKRAGFGTLRLPESLGGAGFTVPQLFSAVIDVAQADPIVAH
MAB_1422c|M.abscessus_ATCC_199 ENPFDQVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAH
MAV_3422|M.avium_104 EPPLRGLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPDLAH
TH_3721|M.thermoresistible__bu ELPFEQIGWLKAAGFGAVRLPVSAGGRGATIPELTRLLIELSTADSNITQ
Mb1706|M.bovis_AF2122/97 AFPAEAVDALRKTGLLGLVLPREIGGMGSGPVEFTEVVAQLSAACGSTAM
Rv1679|M.tuberculosis_H37Rv AFPAEAVDALRKTGLLGLVLPREIGGMGSGPVEFTEVVAQLSAACGSTAM
Mflv_4370|M.gilvum_PYR-GCK QVPDDLREQTKSMGLFGYAIPQEWGGLGLNLAQDVELAMELGYTSLALRS
MMAR_4034|M.marinum_M RVPEDLRDQAKQMGLFGYAIPPQWGGLGLNLVQDVELAMELGYTSLAVRS
MLBr_00737|M.leprae_Br4923 RFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASL
MUL_2626|M.ulcerans_Agy99 RFPQEALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASL
Mvan_3173|M.vanbaalenii_PYR-1 AVLTPQLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVGQ
: :. ** * :. .
MSMEG_5001|M.smegmatis_MC2_155 IFRTHFWFTEERLRTS-SDPVSQRWLREIADGKIFGN-AFSEKGSLAVGS
MAB_1422c|M.abscessus_ATCC_199 IFRTHFWFVEERLRTL-ADPVSAAWLTKVNEGNLFAN-AFSEKGSLAVGS
MAV_3422|M.avium_104 ILRIHYALVEELQVTP-RRPGSDRWIAVVAEGGLIGG-ANAEQSQKSVGG
TH_3721|M.thermoresistible__bu ALRGHFAFAEDRLVAA-PGPGRDRWWQRFAAGDLAGN-AWTEIGDVVLG-
Mb1706|M.bovis_AF2122/97 IYLMH--MAAAVTVAASPPPGLPDLLADMASGKQLGTLAFSEPGSRSHFW
Rv1679|M.tuberculosis_H37Rv IYLMH--MAAAVTVAASPPPGLPDLLADMASGKQLGTLAFSEPGSRSHFW
Mflv_4370|M.gilvum_PYR-GCK MFGTNNGIAGQVLVGYGTDEQKKTWLERIASGEIVASFALTEPGAGSNPS
MMAR_4034|M.marinum_M MFGTNNGIAGQVLVGFGTDEQKARWLEPIASGDVVASFALTEPGAGSSPA
MLBr_00737|M.leprae_Br4923 IPAVN-KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAA
MUL_2626|M.ulcerans_Agy99 IPAVN-KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAG
Mvan_3173|M.vanbaalenii_PYR-1 LLLSHFVVAQAISGLGHTQPAP-RIYADLLAGAQLGN-ASAERGTAHALD
: . . . * :*
MSMEG_5001|M.smegmatis_MC2_155 LVFNTRLLPDPADPGALRLNGEKFYSTGTLFADYLTVTAT-----TDHDS
MAB_1422c|M.abscessus_ATCC_199 LVFNTRLLP---VGDAYRLNGEKFYSTGTLFADYLTVTAT-----TDRDS
MAV_3422|M.avium_104 NHRDTRLVT---TPDGLRLRGRKFYSTGAQFSDYLRITAQ-----DDDGA
TH_3721|M.thermoresistible__bu -EANTKVAPS-GDPGTFVVNGQKFYSTGSIFADWIDLYAQR----TDTGE
Mb1706|M.bovis_AF2122/97 APVSTASADGDG----IAVRADKSWVTSAGFADVYVVSVGS--ADGAAGD
Rv1679|M.tuberculosis_H37Rv APVSTASADGDG----IAVRADKSWVTSAGFADVYVVSVGS--ADGAAGD
Mflv_4370|M.gilvum_PYR-GCK GLRTKAVRDGDGPHSGWILNGQKRFITNAPNADLFVTFARSRPADDKGAG
MMAR_4034|M.marinum_M GLRTKAVRDGDD----WLITGQKRFITNAPVADLFVVFARTRPASDKSPG
MLBr_00737|M.leprae_Br4923 SMRTRAKADGDD----WILNGFKCWITNGGKSTWYTVMAVTDPDKGAN-G
MUL_2626|M.ulcerans_Agy99 AMRTRAKADGDD----WILNGTKCWITNGGKSSWYTVMAVTDPENGAN-G
Mvan_3173|M.vanbaalenii_PYR-1 RRTTVTRRDG-----HWVLNGTKYYATGTLGATWIAVAARIE--GRENGD
: . * : *. : .
MSMEG_5001|M.smegmatis_MC2_155 VANVVIPADREGVRLVDD-WDGFGQRRTGTGTTVLTDVAVSPEEVLTD-S
MAB_1422c|M.abscessus_ATCC_199 VASVIVPGDRDGVRLVDD-WDGFGQRRTGTGTTIFSQVDVAADEILSE-T
MAV_3422|M.avium_104 PTAVVIPVDRAGVEHLDD-WDGIGQRQTGSGTTVFNDVAVADDEVFPL-G
TH_3721|M.thermoresistible__bu FVIAAVDAHADGVTHADD-WDGFGQRTTGSGTSTYRDVRVPAENLIPF-A
Mb1706|M.bovis_AF2122/97 VDLYAVPADTPGLRVAGT-FTGMGLRGN-ASAPMAVDIRIPDSYRLG--E
Rv1679|M.tuberculosis_H37Rv VDLYAVPADTPGLRVAGT-FTGMGLRGN-ASAPMAVDIRIPDSYRLG--E
Mflv_4370|M.gilvum_PYR-GCK IAVFLVPADTPGVDIGAK-DKKMGQEGAWTADVNFTDVEVPDTALVGG-S
MMAR_4034|M.marinum_M IAVFLVPAQSAGVEVGAK-DAKMGQEGAWTADVSFTDVRVDDAALVGG-S
MLBr_00737|M.leprae_Br4923 ISAFIVHKDDEGFSIGPK-EKKLGIKGSPTTELYFDKCRIPGDRIIG--E
MUL_2626|M.ulcerans_Agy99 ISAFVVHKDDEGFVVGPK-ERKLGIKGSPTTELYFENCRVPGDRMIG--E
Mvan_3173|M.vanbaalenii_PYR-1 TATAFVRPDQEGVTLDLESWSAFGQRGTASGEVRLNNVVVDDDLLIDEGP
: . *. :* . : . : .
MSMEG_5001|M.smegmatis_MC2_155 PYDADPVPTVQ-YASLQLFIHAVVAGILANVVDDGVALLRSRERNFSHAV
MAB_1422c|M.abscessus_ATCC_199 PYDAAPVPTTQ-YASLQLYILAIVAGVLRAVVDDGEALLRSRQRNFSHAL
MAV_3422|M.avium_104 --STIGVNRAR-GALVQLYLHAVAAGILRSLTEDAAALVRGRRRTYTFAS
TH_3721|M.thermoresistible__bu T-----RFRYQ-TAFYQLFHLATLAGIAHAATAELAQRVRGRTRTFSHGN
Mb1706|M.bovis_AF2122/97 AGGGFGIMMQTVLPWFNLGNAAVSLGLATAATGAAVKHVGTARL---EHL
Rv1679|M.tuberculosis_H37Rv AGGGFGIMMQTVLPWFNLGNAAVSLGLATAATGAAVKHVGTARL---EHL
Mflv_4370|M.gilvum_PYR-GCK EDLGYRAAMTS-LARGRVHIAALAVGAAQRALDESVAYAATA-----TQG
MMAR_4034|M.marinum_M EDIGYRAAMTS-LARGRVHIAAIAVGAAQRALDESVAYASTA-----TQG
MLBr_00737|M.leprae_Br4923 PGTGFKTALAT-LDHTRPTIGAQAVGIAQGALDAAIVYTKDR-----KQF
MUL_2626|M.ulcerans_Agy99 PGTGFKTALAT-LDHTRPTIGAQAVGIAQGALDAAIAYTKDR-----KQF
Mvan_3173|M.vanbaalenii_PYR-1 PPDPITADPSVLGAFDQALHAAIDIGIARAALEDGAVFVRTRSRPWKEAL
. * *
MSMEG_5001|M.smegmatis_MC2_155 AE---RPTDDPLLQRQLGVLASTAYVARAAVLDAAAAIGAATDSAKDGVP
MAB_1422c|M.abscessus_ATCC_199 TE---RPVDDPLLQRTLGELSATAFAAEATVLAAADAIEAATATLRDGVP
MAV_3422|M.avium_104 AD---TPTADPQLLQIVGEIDAVAYTAHALVRNAAAELAPALQAARDTGI
TH_3721|M.thermoresistible__bu AP---RYAADPQIQQVVGEVMAAAFAAEAIALRAAEDXXXRRRSS-----
Mb1706|M.bovis_AF2122/97 GG---SLAELPTIRAQIARMGTTLAAQKAYLEVAANSVSSPDDTTLTHV-
Rv1679|M.tuberculosis_H37Rv GG---SLAELPTIRAQIARMGTTLAAQKAYLEVAANSVSSPDDTTLTHV-
Mflv_4370|M.gilvum_PYR-GCK GT---PIGDFQLVQAMLADQQTGVMAGRALVRDAARLWVTGQ-DRRIAP-
MMAR_4034|M.marinum_M GV---TIGSFQLVQAMLADQQTGVLAGRALVRDAARMWVSGA-DRRIAP-
MLBr_00737|M.leprae_Br4923 GE---SISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFIS-
MUL_2626|M.ulcerans_Agy99 GK---SISDFQAVQFMLADMAMKVESARLMVYSAAARAERGESNLGFIS-
Mvan_3173|M.vanbaalenii_PYR-1 DAGIERADQEPHVVRRFGELTARLYALEALLARGTALIDEAYAAPEVTR-
: .. . .:
MSMEG_5001|M.smegmatis_MC2_155 DADLAAEAQLKVAKVKVHLDDIAPEAATRLLELGGASAASRQRGLDRHWR
MAB_1422c|M.abscessus_ATCC_199 DAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASRTRNLDRHWR
MAV_3422|M.avium_104 DPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQASALLDRHWR
TH_3721|M.thermoresistible__bu -----------------------------------AAPPRRRTRPRSCWD
Mb1706|M.bovis_AF2122/97 ------------LGVKASVNDAALTITESAMRVCGGAAFSKHLPIERAFR
Rv1679|M.tuberculosis_H37Rv ------------LGVKASVNDAALTITESAMRVCGGAAFSKHLPIERAFR
Mflv_4370|M.gilvum_PYR-GCK ------------SAAKLFCTEMAGKVADLAVQIHGGSGYMREVPVERIYR
MMAR_4034|M.marinum_M ------------SAAKLFCTEMAGKVADLAVQIHGGSGYMRGVPVERIYR
MLBr_00737|M.leprae_Br4923 ------------AASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMR
MUL_2626|M.ulcerans_Agy99 ------------AASKCLASDVAMEVTTDAVQLFGGAGYTVDFPVERMMR
Mvan_3173|M.vanbaalenii_PYR-1 --DAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSGTDGAVNLDRHWR
:
MSMEG_5001|M.smegmatis_MC2_155 NIRTITLHNPVAYKARVIGQNLLHGTPVPANAYF-
MAB_1422c|M.abscessus_ATCC_199 NIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF-
MAV_3422|M.avium_104 NLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF-
TH_3721|M.thermoresistible__bu ATRSSSVCVPRSRPPRCTSP----WAPRPMSG---
Mb1706|M.bovis_AF2122/97 DARAGSVMAPTADALYDFYGRAVTGLPLF------
Rv1679|M.tuberculosis_H37Rv DARAGSVMAPTADALYDFYGRAVTGLPLF------
Mflv_4370|M.gilvum_PYR-GCK DVRLLRLYEGTSEIQKLIIGGGLVKGAKGK-----
MMAR_4034|M.marinum_M DVRLLRLYEGTSEIQQLIIGSNLIKAANR------
MLBr_00737|M.leprae_Br4923 DAKITQIYEGTNQIQRVVMSRALLR----------
MUL_2626|M.ulcerans_Agy99 DAKITQIYEGTNQIQRVVMSRALLR----------
Mvan_3173|M.vanbaalenii_PYR-1 NVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL
: