For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3721 | - | - | 100% (353) | putative acyl-CoA dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_3393 | - | 1e-36 | 35.22% (301) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. thermoresistible (build 8) | TH_2583 | - | 7e-09 | 28.51% (221) | PUTATIVE peptidase S1 and S6, chymotrypsin/Hap |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0897 | fadE10 | 4e-10 | 25.89% (224) | acyl-CoA dehydrogenase FADE10 |
| M. gilvum PYR-GCK | Mflv_2446 | - | 4e-09 | 28.45% (239) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv0873 | fadE10 | 4e-10 | 25.89% (224) | acyl-CoA dehydrogenase FADE10 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1422c | - | 2e-49 | 38.36% (292) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_4532 | fadE13 | 3e-08 | 30.20% (202) | acyl-CoA dehydrogenase FadE13 |
| M. avium 104 | MAV_3422 | - | 3e-43 | 36.30% (303) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4547 | - | 1e-58 | 42.71% (288) | acyl-CoA dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_4704 | fadE13 | 3e-09 | 30.20% (202) | acyl-CoA dehydrogenase FadE13 |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 9e-23 | 30.23% (301) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3721|M.thermoresistible__bu --------------------------------------------VPYFDE
MSMEG_4547|M.smegmatis_MC2_155 ------------------------------------------MSTDSFYL
MAB_1422c|M.abscessus_ATCC_199 ---------------------------------------------MTSAP
MAV_3422|M.avium_104 ---------------------------------------------MPVAF
Mb0897|M.bovis_AF2122/97 MAQQTQVTEEQARALAEESRESGWDKPSFAKELFLGRFPLGLIHPFPKPS
Rv0873|M.tuberculosis_H37Rv MAQQTQVTEEQARALAEESRESGWDKPSFAKELFLGRFPLGLIHPFPKPS
MMAR_4532|M.marinum_M -------------------------------------------MSIWNTP
MUL_4704|M.ulcerans_Agy99 -------------------------------------------MSIWNTP
Mflv_2446|M.gilvum_PYR-GCK ------------------------------------------MRRDLFTE
Mvan_3173|M.vanbaalenii_PYR-1 ----------------------------------------MATDITDRIP
TH_3721|M.thermoresistible__bu QR----FEALAAEFRPVFDRIRAGAVQRERD--RELPFEQIGWLKAAGFG
MSMEG_4547|M.smegmatis_MC2_155 KRPTGYDAELRSVFRPIFARIAEGNVGRERN--RILPHEQVRWLNEAGFG
MAB_1422c|M.abscessus_ATCC_199 SVLEIRALPGTDTYRNLLAQVAEGARDRDLD--DENPFDQVRLLKEAGFG
MAV_3422|M.avium_104 HRQDT--PAGAAAVQPVLAEIAADYRLRLADGGTEPPLRGLKLVRDHRLG
Mb0897|M.bovis_AF2122/97 DAEEARTEAFLVKLREFLDTVDGSVIERAAQ----IPDEYVKGLAELGCF
Rv0873|M.tuberculosis_H37Rv DAEEARTEAFLVKLREFLDTVDGSVIERAAQ----IPDEYVKGLAELGCF
MMAR_4532|M.marinum_M EREELRKTVRSFAEREVLPHID--EWERTGE----LPRDLHRRAGAAGLL
MUL_4704|M.ulcerans_Agy99 EREELRKSVRSFAEREVLPHID--EWERTGE----LPLDLHRRAGAAGLL
Mflv_2446|M.gilvum_PYR-GCK DHEAFRELARDFVEKEVVPHYP--DWEKGGR----MPRPVFEQMGSLGIL
Mvan_3173|M.vanbaalenii_PYR-1 DTLLRTPADALAAAEEVAEAIAAGSAERERAG--AVLTPQLRLVAESGLL
. . :
TH_3721|M.thermoresistible__bu AVRLPVSAGGRGATIPELTRLLIELSTADSNITQALRGHFAFAEDRLVAA
MSMEG_4547|M.smegmatis_MC2_155 TLRIPAEQGGFGASLEQTFQLLAELGQADANVAHIWRNHLAFVEDRLNAP
MAB_1422c|M.abscessus_ATCC_199 RLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAHIFRTHFWFVEERLRTL
MAV_3422|M.avium_104 ALRLARELGGAGYTAPEFFDYLVALAAADPDLAHILRIHYALVEELQVTP
Mb0897|M.bovis_AF2122/97 GLKIPSEYGGLNMSQVAYNRVLMMVTTVHSSLGALLSAHQSIGVPEPLKL
Rv0873|M.tuberculosis_H37Rv GLKIPSEYGGLNMSQVAYNRVLMMVTTVHSSLGALLSAHQSIGVPEPLKL
MMAR_4532|M.marinum_M GAGLPESAGGGGGDGADSVIICEQMHQSGAPGGVFASLFTCGIAVPHMIA
MUL_4704|M.ulcerans_Agy99 GAGLPESAGGGGGDGADSVIICEQMHQSGAPGGVFASLFTCGIAVPHMIA
Mflv_2446|M.gilvum_PYR-GCK GVAIPEEYGGGGQPDYRYNVVLQEEAAR-ALVTLSTVRTQLEVILPYFLH
Mvan_3173|M.vanbaalenii_PYR-1 GISVPTAHGGPGLPASTVVEVLRRLARADGAVGQLLLSHFVVAQAISGLG
:. ** .
TH_3721|M.thermoresistible__bu PGPGR--DRWWQRFAAGDLAGNAWTEIGDVVLGEANTKVAPSGDPG----
MSMEG_4547|M.smegmatis_MC2_155 VTEEN--NTWIKRFLAGEFVGGGWTEANNGTLANIATTITARDD------
MAB_1422c|M.abscessus_ATCC_199 ADPVS--AAWLTKVNEGNLFANAFSEKGSLAVGSLVFNTRLLPVGD----
MAV_3422|M.avium_104 RRPGS--DRWIAVVAEGGLIGGANAEQSQKSVGGNHRDTRLVTTPD----
Mb0897|M.bovis_AF2122/97 AGTAEQKRRFLPRCAAG-AISAFLLTEPDVGSDPARMASTATPIDDG--Q
Rv0873|M.tuberculosis_H37Rv AGTAEQKRRFLPRCAAG-AISAFLLTEPDVGSDPARMASTATPIDDG--Q
MMAR_4532|M.marinum_M SGDERLIEEFVRPTLAGDKIGALAITEPGGGSDVGHLRTSAVRDGD----
MUL_4704|M.ulcerans_Agy99 SGDERLIEEFVRPTLAGNKIGALAITEPGGGSDVGHLRTSAVREGD----
Mflv_2446|M.gilvum_PYR-GCK YANAEQRERWFPGLASGTLLTAIAMTEPGTGSDLAGMRTTAVRDGSGPDA
Mvan_3173|M.vanbaalenii_PYR-1 HTQPAP--RIYADLLAGAQLGNASAERG--TAHALDRRTTVTRRDG----
*
TH_3721|M.thermoresistible__bu TFVVNGQKFYSTGSIFADWIDLYAQRTDTGEF-----VIAAVDAHADGVT
MSMEG_4547|M.smegmatis_MC2_155 HWLVSGAKYYATGSLYADWLDVIG-RGDDGEL-----WTALVRSDDPGVK
MAB_1422c|M.abscessus_ATCC_199 AYRLNGEKFYSTGTLFADYLTVTA-TTDRDSV-----ASVIVPGDRDGVR
MAV_3422|M.avium_104 GLRLRGRKFYSTGAQFSDYLRITA-QDDDGAP-----TAVVIPVDRAGVE
Mb0897|M.bovis_AF2122/97 AYELEGVKLWTTNGVVADLLVVMARVPRSEGHRG-GISAFVVEADSPGIT
Rv0873|M.tuberculosis_H37Rv AYELEGVKLWTTNGVVADLLVVMARVPRSEGHRG-GISAFVVEADSPGIT
MMAR_4532|M.marinum_M HFIVNGAKTYITSGVRADFVVTAVRTGGPGAG---GVSLLVVEKGTPGFV
MUL_4704|M.ulcerans_Agy99 HFIVNGAKTYITSGVRADFVVTAVRTGGPGAG---GVSLLVVEKGTPGFV
Mflv_2446|M.gilvum_PYR-GCK DYIVNGAKTFITGGMQADLVIVVARTSTDPDNRRKGLTLLVVEDGMEGFT
Mvan_3173|M.vanbaalenii_PYR-1 HWVLNGTKYYATGTLGATWIAVAARIEGRENG---DTATAFVRPDQEGVT
: * * : *. : : : *.
TH_3721|M.thermoresistible__bu H-ADDWDGFGQRTTGSGTSTYRDVRVPAENLIPFA-------TRFRYQTA
MSMEG_4547|M.smegmatis_MC2_155 L-VDDWRGFGQRATASGSVHYDNARAERGNVFPAV-------ERFAYQPH
MAB_1422c|M.abscessus_ATCC_199 L-VDDWDGFGQRRTGTGTTIFSQVDVAADEILSETPY--DAAPVPTTQYA
MAV_3422|M.avium_104 H-LDDWDGIGQRQTGSGTTVFNDVAVADDEVFPLG----STIGVNRARGA
Mb0897|M.bovis_AF2122/97 V-ERRNKFMGLRGIENGVTRLHRVRVPKDNLIGREG---DGLKIALTTLN
Rv0873|M.tuberculosis_H37Rv V-ERRNKFMGLRGIENGVTRLHRVRVPKDNLIGREG---DGLKIALTTLN
MMAR_4532|M.marinum_M V-SRKLDKMGWRSSDTAELSYTDARVPAANLVGAEN---SGFAQIAQAFV
MUL_4704|M.ulcerans_Agy99 V-SRKLDKMGWRSSDTAELSYTDARIPAANLVGAEN---SGFAQIAQAFV
Mflv_2446|M.gilvum_PYR-GCK R-GRELEKMGCKVQDTAELSFVDVRVPAANVLGEVD---EAFGYLGHNLA
Mvan_3173|M.vanbaalenii_PYR-1 LDLESWSAFGQRGTASGEVRLNNVVVDDDLLIDEGPPPDPITADPSVLGA
:* : .. . :.
TH_3721|M.thermoresistible__bu FYQLFHLATLAGIAHAATAELAQRVRGRTRTFSHGNAP---RYAADPQIQ
MSMEG_4547|M.smegmatis_MC2_155 FYQIAMLAVLTGITKAVQRDGSAALKQRKRNYPQGLSE---VPSDDAQLL
MAB_1422c|M.abscessus_ATCC_199 SLQLYILAIVAGVLRAVVDDGEALLRSRQRNFSHALTE---RPVDDPLLQ
MAV_3422|M.avium_104 LVQLYLHAVAAGILRSLTEDAAALVRGRRRTYTFASAD---TPTADPQLL
Mb0897|M.bovis_AF2122/97 AGRLSLPAIATGVAKQALKIAREWSVERVQWGKPVGQH---EAVASKISF
Rv0873|M.tuberculosis_H37Rv AGRLSLPAIATGVAKQALKIAREWSVERVQWGKPVGQH---EAVASKISF
MMAR_4532|M.marinum_M SERIALAAQAYSSAQRCLDITVQWCRDRETFGRPLISR---QSVQNTLAE
MUL_4704|M.ulcerans_Agy99 SERIALAAQAYSSAQRCLDITVQWCRDRETFGRPLISR---QSVQNTLAE
Mflv_2446|M.gilvum_PYR-GCK QERLTVAVGSVAQARSAIAAAIDYTRNRKAFGTPVASF---QNTKFELAA
Mvan_3173|M.vanbaalenii_PYR-1 FDQALHAAIDIGIARAALEDGAVFVRTRSRPWKEALDAGIERADQEPHVV
: . . : *
TH_3721|M.thermoresistible__bu QVVGEVMAAAFAAEAIALRAAEDXX--XRRRSSAAPPRRR----------
MSMEG_4547|M.smegmatis_MC2_155 QVIGEVSAEAFGAEAALALSARTLDRVVAGRLAGSEDRARQLLIDAEVAV
MAB_1422c|M.abscessus_ATCC_199 RTLGELSATAFAAEATVLAAADAIEAATATLRDGVPDAQLAQEAQ--VAV
MAV_3422|M.avium_104 QIVGEIDAVAYTAHALVRNAAAELAPALQAARDTGIDPELEAAAS--IAA
Mb0897|M.bovis_AF2122/97 IAATNYALDAVVELSSQMADEGRNDIRIEAALAKLWSSEMACLVG-----
Rv0873|M.tuberculosis_H37Rv IAATNYALDAVVELSSQMADEGRNDIRIEAALAKLWSSEMACLVG-----
MMAR_4532|M.marinum_M MARRIDVARVYSRSVVERQLAGEHDLIPQVCFAKNTAVEAGEWVA-----
MUL_4704|M.ulcerans_Agy99 MARRIDVARVYSRSVVERQLAGEHDLIPQVCFAKNTAVEAGEWVA-----
Mflv_2446|M.gilvum_PYR-GCK CSTEVEAAQAMLDRAVSLHVEGELSG-ADAARTKLFCTEMQQRVV-----
Mvan_3173|M.vanbaalenii_PYR-1 RRFGELTARLYALEALLARGTALIDEAYAAPEVTRDAAAQASLTVA----
TH_3721|M.thermoresistible__bu ------------TRPRSCWDATRSSSVC-------VPR--------SRPP
MSMEG_4547|M.smegmatis_MC2_155 TQAQLVIIGAALRSTTKVFDALGASAVS-------EELGLDRHWRNARTL
MAB_1422c|M.abscessus_ATCC_199 AKAKVHIDAVALDAATKLLDLGGASAAS-------RTRNLDRHWRNIRTI
MAV_3422|M.avium_104 ARVKVAIQEPALRAASRVFDAGGASAVQ-------ASALLDRHWRNLRTL
Mb0897|M.bovis_AF2122/97 ------------DELLQIRGGRGYETAESLAARGERAVPVEQMVRDLRIN
Rv0873|M.tuberculosis_H37Rv ------------DELLQIRGGRGYETAESLAARGERAVPVEQMVRDLRIN
MMAR_4532|M.marinum_M ------------NQAVQLFGGMGYMAES----------EIERQYRDMRIL
MUL_4704|M.ulcerans_Agy99 ------------NQAVQLFGGMGYMAES----------EIERQYRDMRIL
Mflv_2446|M.gilvum_PYR-GCK ------------DRCLQLFGGYGYMMEY----------PIARLYTDARVA
Mvan_3173|M.vanbaalenii_PYR-1 -AAKALAQQDAVEIAGAIFELTGTSGTDG-------AVNLDRHWRNVRVH
*
TH_3721|M.thermoresistible__bu RCTSPWAPRP-------MSG------------------------------
MSMEG_4547|M.smegmatis_MC2_155 ASHNPVVYKARILGDWFINGKDPVPDLASRGRGGQGN-------------
MAB_1422c|M.abscessus_ATCC_199 SLHNPVHYKARVIGQNLLHGTPLPANAYF---------------------
MAV_3422|M.avium_104 FSHNPTVYKARVLGDVVVNGAALPDTSFF---------------------
Mb0897|M.bovis_AF2122/97 RIFEGSSEIMRLLIAREAVDAHLTAAGDLANPKADLRQKAAAAAGASGFY
Rv0873|M.tuberculosis_H37Rv RIFEGSSEIMRLLIAREAVDAHLTAAGDLANPKADLRQKAAAAAGASGFY
MMAR_4532|M.marinum_M GIGGGTTEILTALAAKLLGYQS----------------------------
MUL_4704|M.ulcerans_Agy99 GIGGGTTEILTALAAKLLGYQS----------------------------
Mflv_2446|M.gilvum_PYR-GCK RIYAGTSEVMKVMIAKSLGL------------------------------
Mvan_3173|M.vanbaalenii_PYR-1 SLHDPARWKYVHLGNHTLHDTRPPRLGLIL--------------------
TH_3721|M.thermoresistible__bu --------------------------------------------------
MSMEG_4547|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1422c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3422|M.avium_104 --------------------------------------------------
Mb0897|M.bovis_AF2122/97 AKWLPKLVFGEGQLPTTYREFGALATHLRFVERSSRKLARNTFYGMARWQ
Rv0873|M.tuberculosis_H37Rv AKWLPKLVFGEGQLPTTYREFGALATHLRFVERSSRKLARNTFYGMARWQ
MMAR_4532|M.marinum_M --------------------------------------------------
MUL_4704|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2446|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3173|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3721|M.thermoresistible__bu --------------------------------------------------
MSMEG_4547|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1422c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3422|M.avium_104 --------------------------------------------------
Mb0897|M.bovis_AF2122/97 ASLEKKQGFLGRIVDIGAELFAISAACVRAEAQRTADPVEGEQAYELAEA
Rv0873|M.tuberculosis_H37Rv ASLEKKQGFLGRIVDIGAELFAISAACVRAEAQRTADPVEGEQAYELAEA
MMAR_4532|M.marinum_M --------------------------------------------------
MUL_4704|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2446|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3173|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3721|M.thermoresistible__bu --------------------------------------------------
MSMEG_4547|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1422c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3422|M.avium_104 --------------------------------------------------
Mb0897|M.bovis_AF2122/97 FCQQATLRVEALFDALWSNTDSIDVRLANDVLEGRYTWLEQGILDQSEGT
Rv0873|M.tuberculosis_H37Rv FCQQATLRVEALFDALWSNTDSIDVRLANDVLEGRYTWLEQGILDQSEGT
MMAR_4532|M.marinum_M --------------------------------------------------
MUL_4704|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2446|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3173|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3721|M.thermoresistible__bu --------------------------------
MSMEG_4547|M.smegmatis_MC2_155 --------------------------------
MAB_1422c|M.abscessus_ATCC_199 --------------------------------
MAV_3422|M.avium_104 --------------------------------
Mb0897|M.bovis_AF2122/97 GPWIASWEPGPSTEANLARRFLTVSPSSEAKL
Rv0873|M.tuberculosis_H37Rv GPWIASWEPGPSTEANLARRFLTVSPSSEAKL
MMAR_4532|M.marinum_M --------------------------------
MUL_4704|M.ulcerans_Agy99 --------------------------------
Mflv_2446|M.gilvum_PYR-GCK --------------------------------
Mvan_3173|M.vanbaalenii_PYR-1 --------------------------------